4 fluoroiodobenzene Sigma
The method of making 4-fluoroiodobenzene
If you want to make 4-fluoroiodobenzene (made by Sigma as a model), you should follow the following method.
Prepare all kinds of drugs and utensils first. Take an appropriate amount of starting materials, its properties and reactivity need to be carefully studied. In a clean reactor, place accurately measured reactants. The temperature and pressure of the reaction environment are all important factors and must be precisely controlled. Add a suitable catalyst. The amount of catalyst depends on the rate and yield of the reaction, so adjust it carefully.
When reacting, closely observe its phenomenon, or there may be color changes, gas escape, etc. Use the instrument to measure the reaction process in a timely manner to ensure that it follows expectations. After the reaction is completed, it is separated and purified. Or use the method of distillation to separate 4-fluoroiodobenzene from impurities according to the difference in boiling point of each substance; or use the method of extraction to select the appropriate extractant to extract the desired substance.
After purification, check the purity and structure of the product in detail. Use spectroscopy techniques, such as NMR, IR, etc., to ensure that it is the desired 4-fluoroiodobenzene and free of impurities. In this way, it is like 4-fluoroiodobenzene of Sigma quality.
