1bromo4fluoro2iodobenzene properties applications synthesis
1 - bromo - 4 - fluoro - 2 - iodobenzene
1 - bromo - 4 - fluoro - 2 - iodobenzene
1 - bromo - 4 - fluoro - 2 - iodobenzene, the chemical formula is\ (C_ {6} H_ {3} BrFI\), which is colored to light. It has a certain density, and the phase density under normal conditions is generally high for benzene derivatives due to the presence of bromine, fluorine and iodine atoms in the molecule. The melting temperature is low, and the boiling temperature is affected by the molecular force and the molecular weight. Due to the multi-element atoms, the molecular force increases, and the boiling phase is high. Compounds are insoluble in water because of their non-soluble properties, while water is soluble. According to the principle of similar miscibility, the two are mutually soluble. But they are soluble in multi-soluble substances, such as ether, carbon tetrachloride, etc. Because of their multi-soluble properties or weak properties, 1-bromo-4-fluoro-2-iodobenzene is similar.
Second, the use of
In the field of chemical synthesis, 1-bromo-4-fluoro-2-iodobenzene plays an important role. First, aromatic compounds that can be used for construction. Because the molecule contains three different elements of the atom, the different anti-activity of the element can be used to replace the anti-element step by step. For example, in this case, the iodine atom can be used to form a new carbon-carbon atom, such as a Grignard atom, and a specific carbon-carbon atom can be introduced, which provides the possibility of synthesizing materials with specific properties and functions. Second, in the field of materials, it can be used as a starting material for synthesizing new optical materials. Through chemical modification, the photophysics of materials can be improved, such as light waves, quantum efficiency, etc., to meet the needs of different optical applications, such as optical diodes (OLEDs).
III. Synthesis
1. ** Starting material with benzene derivatives **: 4-fluoro-2-iodoaniline can be used. First, the diazotization reaction rate, the amino group reaction rate, and then the bromination reaction rate. Sandmeyer reaction rate to obtain 1-bromo-4-fluoro-2-iodobenzene. In this reaction process, the formation of diazonium needs to be carried out under low temperature and acid conditions to maintain the quality of diazonium and avoid its decomposition. And the bromination reaction rate needs to be controlled to improve the performance of the target material.
2. ** Mixture method **: With 1-bromo-4-fluorobenzene raw materials, in the presence of catalysis, iodization such as iodization can be used to replace the atom at a specific position on the benzene with an iodine atom to obtain 1-bromo-4-fluoro-2-iodobenzene. Catalysis can be used as a catalyst or a catalyst, etc., and the reaction is usually performed in a solution. It is necessary to pay attention to the operation of water and oxygen in the reaction system to prevent side reactions and improve the reaction efficiency.
