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(S)-5-Chloro-Alpha-(Cyclopropylethynyl)-2-Amino-Alpha-(Trifluoromethyl)-Benzenemethanol

(S)-5-Chloro-Alpha-(Cyclopropylethynyl)-2-Amino-Alpha-(Trifluoromethyl)-Benzenemethanol

Hongda Chemical

Specifications

HS Code

133689

Chemical Formula C13H10ClF3NO
Molecular Weight 289.675

As an accredited (S)-5-Chloro-Alpha-(Cyclopropylethynyl)-2-Amino-Alpha-(Trifluoromethyl)-Benzenemethanol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of (s)-5 - chloro - α-(cyclopropylethynyl)-2 - amino - α-(trifluoromethyl) - benzenemethanol in sealed vial.
Storage ( s)-5 - chloro - α - (cyclopropylethynyl)-2 - amino - α - (trifluoromethyl) - benzenemethanol should be stored in a cool, dry place, away from heat sources and direct sunlight. Keep it in a tightly sealed container to prevent moisture absorption and potential degradation. Store it separately from incompatible substances to avoid chemical reactions. Follow relevant safety regulations for storage.
Shipping Shipping of 5 - chloro - α - (cyclopropylethynyl) - 2 - amino - α - (trifluoromethyl) - benzenemethanol must comply with chemical transport regulations. It will be carefully packaged to prevent damage, with documentation for safe and proper handling during transit.
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(S)-5-Chloro-Alpha-(Cyclopropylethynyl)-2-Amino-Alpha-(Trifluoromethyl)-Benzenemethanol (S)-5-Chloro-Alpha-(Cyclopropylethynyl)-2-Amino-Alpha-(Trifluoromethyl)-Benzenemethanol
General Information
Historical Development
Alas! Today there is a thing called (S) -5 -chloro - α - ( cyclopropyl ethynyl) -2 -amino - α - ( trifluoromethyl) -benzyl alcohol. The research and development of this thing has gone through years. In the past, various sages studied diligently in the field of chemistry, exploring the properties of substances and the rules of reaction. At first, I only knew a little about its related basics. After countless experiments, or subtle changes between bottles and dishes, or opportunities for breakthroughs in the data. Gradually clarify the synthesis path of this compound, from ignorance to knowledge, every step is concentrated. From its concept to maturity, it is like a babbling trickle converging into a river. Looking at its historical evolution, it is the crystallization of the wisdom and sweat of many chemists, adding a bright pearl to the chemical treasure house and paving the way for subsequent research and application.
Product Overview
There is now a product named (S) - 5 - chloro - α - ( cyclopropyl ethynyl) - 2 - amino - α - ( trifluoromethyl) - benzyl alcohol. Its shape is specific and contains a unique chemical structure. This is prepared by fine chemical techniques.
The characteristics of this product are of special significance in the field of chemistry. The combination of chlorine, cyclopropyl ethynyl, amino and trifluoromethyl in its structure gives it special physical and chemical properties. Or it can be used in organic synthesis and other fields to provide new possibilities for many chemical reactions, or it has potential applications in fields such as pharmaceutical research and development. With its unique structure and properties, it may be able to act on specific biological targets, contributing to the creation of new drugs.
Physical & Chemical Properties
There is now a substance named (S) -5 -chloro-alpha- (cyclopropylethynyl) -2 -amino-alpha- (trifluoromethyl) -benzyl alcohol. The physical and chemical properties of this substance are relevant to our research. Its color state is also in the shape of crystal or powder, and its appearance can be seen. Its melting point is high and low, just like the characteristics of the substance. At a specific temperature, the state of matter gradually changes, which is a sign of energy conversion. In terms of solubility, it may be soluble or insoluble in various solvents, revealing the mystery of its affinity with solvent molecules. As for chemical activity, due to its unique structure, it contains chlorine, trifluoromethyl and other groups, which may easily react with other substances for substitution and addition, resembling an active role on the stage of chemical reactions. Exploring the properties of this substance is like exploring the unknown, which can open up paths for subsequent applications, and may be of extraordinary use in the fields of chemical industry and medicine.
Technical Specifications & Labeling
Today there is a product, the name (S) - 5 - chloro - α - ( cyclopropyl ethynyl) - 2 - amino - α - ( trifluoromethyl) - benzyl alcohol. To clarify its technical specifications and identification (product parameters), it is time to study it in ancient ways.
This substance is also prepared in accordance with precise regulations. From the selection of raw materials, it is necessary to be pure and free of impurities, and the amount of each material is in a fixed ratio. In the reactor, control the temperature and pressure to make it orderly. When reacting, observe its changes and adjust according to regulations.
As for the logo, when the name is stated, the book is clearly placed, and the chemical formula is attached, which makes it easy for people to recognize. Mark the number of its purity, indicating the amount of impurities contained. Remember its properties, such as color and state. Also record its storage method to prevent its deterioration. In this way, the details of the technical specifications and labels of this thing can be passed down to future generations, so that those who use it can learn from it.
Preparation Method
The method of preparing (S) -5 -chloro-alpha- (cyclopropyl ethynyl) -2 -amino-alpha- (trifluoromethyl) -benzyl alcohol is related to the raw materials and production process, reaction steps and catalytic mechanism. First, the appropriate raw materials need to be selected, such as benzene derivatives with specific structures, halogenated compounds and reagents containing cyclopropyl ethynyl groups and trifluoromethyl groups. In the reaction step, the benzene derivative is first reacted with the halogenated compound under specific conditions to form a preliminary structure. Then cyclopropyl ethynyl is introduced, and the reaction temperature, duration and catalyst need to be controlled. Then through the modification step, the amino group is added and the α-site structure is adjusted. The catalyst used is a metal complex or the like to promote the reaction to proceed efficiently and selectively. After a series of delicate steps, the target product can be obtained.
Chemical Reactions & Modifications
I will study the reaction and modification of (S) -5-Chloro-Alpha- (Cyclopropylethynyl) -2-Amino-Alpha- (Trifluoromethyl) -Benzenemethanol. A chemist, studying the study of material changes. This compound has a delicate structure and unique characteristics. The way of reaction is related to the breaking and formation of bonds, and the rearrangement of atoms. To change its properties, you need to clarify its mechanism and observe its environment. Or adjust the temperature, pressure, or add a catalyst to lead the reaction to the desired path. When modifying, consider its impact, taking into account the purity of the product and the optimization of its properties. This is a common way of chemical research. In the exploration of the reaction and modification of this compound, we also follow this principle to achieve good results, adding bricks and mortar to the field of chemistry and promoting its progress and development.
Synonyms & Product Names
(S) -5-chloro-alpha- (cyclopropylethynyl) -2-amino-alpha- (trifluoromethyl) benzyl alcohol is a compound whose nickname and trade name are also valued by researchers in today's chemical field. Although this substance is known to everyone under scientific names, in actual research and development and trading scenarios, nicknames and trade names are more commonly used.
In the development of chemistry in the past, many substances have different names. When we study this (S) -5-chloro-alpha- (cyclopropylethynyl) -2-amino-alpha- (trifluoromethyl) benzyl alcohol, we must check its previous nicknames and trade names in the market. In this way, there can be no mistakes in literature review, purchase of experimental materials, etc. Or because of the unique structure and different properties, it may have unique names for different uses and manufacturers. Therefore, knowing its synonyms and trade names is an indispensable part of in-depth research on this thing.
Safety & Operational Standards
(I am a chemical researcher, and today I am discussing the safety and operation specifications of (S) -5 -chloro - α - ( cyclopropyl ethynyl) -2 -amino - α - ( trifluoromethyl) -benzyl alcohol.)
This chemical product has a unique molecular structure, and its chlorine, cyclopropyl ethynyl, amino and trifluoromethyl are connected to benzyl alcohol. During operation, the ventilation of the first environment. Because it may be volatile, if it accumulates in a closed space, it may cause qualitative changes in the air and endanger the health of the operator.
Furthermore, contact with this product, complete protective equipment is necessary. Gloves should be chemically resistant to prevent the product from penetrating into the skin of the hands; anti-goggles can protect the eyes from accidental splashing; wearing protective clothing can prevent the product from contaminating the clothing and body.
When storing, choose a cool, dry and well-ventilated place. Keep away from fire and heat sources to prevent chemical changes due to rising temperature and cause danger. This product may react violently with certain substances, so it cannot be stored in one place with strong oxidants, strong acids and alkalis.
During operation, strictly follow the standard steps. When weighing, use accurate equipment to ensure that the dosage is correct; during mixing and reaction, pay close attention to changes in temperature and pressure. If there is any abnormality, take measures quickly. After the experiment, properly dispose of the remaining products and waste, and do not discard them at will to avoid polluting the environment. In this way, the operation is safe and the product research is advanced in an orderly manner.
Application Area
(S) -5 - - α - ( cyclopropylethynyl) -2 -amino - α - ( trifluoromethyl) -benzyl alcohol, the application field of this substance is particularly critical. The chemical research of ancient times has many uses for exploring new substances. This compound may have unique capabilities in the field of pharmaceutical research and development. With its exquisite structure and unique characteristics, it can be used as a key component of targeted drugs, accurately acting on diseased cells and helping to heal diseases. Or in materials science, because of its special chemical properties, it can provide an opportunity for the creation of new materials, making materials have extraordinary properties, such as better stability and functionality. Its application potential is like a treasure hidden in the fog, waiting for our chemical researchers to use the key to study and open the door to its application, contributing to the development of various fields.
Research & Development
I have been dedicated to the research and development of (S) -5-chloro-alpha - (cyclopropylethynyl) -2-amino-alpha - (trifluoromethyl) benzyl alcohol for a long time. This compound has unique characteristics and great potential. I have delved into its synthesis path and tried various methods to optimize the process and improve the yield and purity.
During the experiment, the reaction conditions were carefully regulated, and the temperature, pressure, and catalyst dosage were all cautious. At the beginning, the results were not obvious, and the yield was quite low, but I was not discouraged. I have repeatedly studied ancient books and cutting-edge literature, learned from the methods of the sages, and combined with current technology. In the end, I have obtained something, and after many improvements, the synthesis method has been perfected day by day.
I also consider its application prospects. This product may have extraordinary value in the fields of medicine and materials. Further investigation will be conducted in the future, hoping to open up a wide range of fields for it, promote progress in related fields, and contribute to our generation's chemical research.
Toxicity Research
In the field of chemistry, there is a name (S) - 5 - Chloro - Alpha - (Cyclopropylethynyl) - 2 - Amino - Alpha - (Trifluoromethyl) - Benzenemethanol. We devote ourselves to toxicological research.
This substance also has a unique molecular structure, which may show strange properties in reactions. However, its toxicity is unknown, so it must be carefully studied. Observe its shape, observe its change, and test it with various experiments. Or in the body of a living being, observe its influence, observe its growth and metabolic changes.
We study day and night to fully understand the secrets of its toxicity. It may damage the structure of cells, or disrupt the balance of the body. Only by scientific methods can we explore the depth of its toxicity, and when using this substance for the world, understand its advantages and disadvantages, prevent its harm and benefit from it. This is the important task of our chemical researchers.
Future Prospects
Today there is a product named (S) -5 -chloro-alpha- (cyclopropylethynyl) -2 -amino-alpha- (trifluoromethyl) -benzyl alcohol. We are chemical researchers. Looking at the characteristics and structure of this product, we are excited to think about its future development.
Although this product is in front of our eyes, its future scene is like a star waiting to be discovered. Its unique structure may lead to new paths in chemical reactions, which can be used in pharmaceutical research and development, or it can become a sharp blade against diseases and eliminate diseases for patients; in the creation of materials, it may also bring novelty and give materials extraordinary properties.
With the heart of exploration, we should hold the pen of research and draw the future of this object. With time and unremitting efforts, it may be able to make it shine in various fields, contribute to human well-being, live up to the mission of scientific research, and develop the infinite possibilities of the future.
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Frequently Asked Questions

As a leading (S)-5-Chloro-Alpha-(Cyclopropylethynyl)-2-Amino-Alpha-(Trifluoromethyl)-Benzenemethanol supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What is the chemical structure of (S) -5-Chloro-Alpha- (Cyclopropylethynyl) -2-Amino-Alpha- (Trifluoromethyl) -Benzenemethanol?
This is the chemical name of (S) - 5 - - α - ( cyclopropylethynyl) - 2 - amino - α - ( trifluoromethyl) - benzyl alcohol. To know its chemical structure, it is necessary to analyze the meanings of each part of its name.
" (S) " means that the compound is chiral and is of the S configuration. " 5-Chloro "indicates that the benzene ring has a chlorine atom substituted at position 5 ;“α - ( cyclopropyl ethynyl) " refers to the cyclopropyl ethynyl group attached to the α-position carbon connected to the benzene ring; "2-amino" epitene ring has an amino group ;“α - ( trifluoromethyl) "The alpha-position carbon also has trifluoromethyl;" benzyl alcohol "indicates that this compound has benzyl alcohol as the basic structure.
Its chemical structure is roughly as follows: benzene ring as the base, chlorine atom at No. 5, amino group at No. 2; benzene ring side chain α-carbon is connected with cyclopropyl ethynyl group at one end, trifluoromethyl group at the other end, and this α-carbon is also connected with hydroxyl group to form benzyl alcohol structure. The side chain of cyclopropyl ethynyl group, cyclopropyl group has a ternary carbon ring, ethynyl group is a carbon-carbon triple bond structure; trifluoromethyl is a carbon atom connected to three fluorine atoms. In this way, the chemical structure of this compound will be roughly clear.
What are the physical properties of (S) -5-Chloro-Alpha- (Cyclopropylethynyl) -2-Amino-Alpha- (Trifluoromethyl) -Benzenemethanol?
(S) - 5 -chloro - α - ( cyclopropylethynyl) - 2 -amino - α - ( trifluoromethyl) -benzyl alcohol, which is an organic compound. Its physical properties are as follows:
In normal condition, it may be a white to off-white solid. Due to the interaction of many groups in the molecular structure, the molecules are arranged in an orderly manner and will be solid to a certain extent.
As for the melting point, due to the strong electronegativity of groups such as chlorine and trifluoromethyl, the intermolecular force is enhanced, and the estimated melting point is relatively high. However, the exact value needs to be determined accurately by experiments.
In terms of solubility, the molecule contains polar amino and hydroxyl groups, as well as non-polar benzene ring, cyclopropyl ethynyl group and other groups. Therefore, in polar organic solvents such as methanol and ethanol, there may be a certain solubility, because polar groups can form hydrogen bonds with polar solvents and other interactions; in non-polar organic solvents such as n-hexane, the solubility may be limited, because the non-polar part and the non-polar solvent have a weak force.
The density is also affected by the molecular structure. Many halogen atoms increase the molecular weight, the structure is compact, and the density may be greater than that of common organic solvents and water. However, the actual density still needs to be based on experimental measurements.
The physical properties of this compound have a profound impact on its application in chemical synthesis, drug development and other fields. By understanding its physical properties, we can better manipulate the reaction conditions, achieve the desired synthesis goals, and lay the foundation for its potential application in the pharmaceutical field.
What is the main use of (S) -5-Chloro-Alpha- (Cyclopropylethynyl) -2-Amino-Alpha- (Trifluoromethyl) -Benzenemethanol?
(S) - 5 - α - ( cyclopropyl ethynyl) - 2 - amino - α - ( trifluoromethyl) - benzyl alcohol, an organic compound. It has a wide range of uses and is often a key intermediate in the synthesis of specific drugs in the field of medicinal chemistry. With its unique chemical structure, it can play a key role in the construction of biologically active molecular structures and help to develop new drugs for specific diseases.
In the field of organic synthesis, as a characteristic structural unit, it can participate in a variety of chemical reactions, such as the formation reaction of carbon-carbon bonds and carbon-nitrogen bonds, etc., so as to prepare organic materials with complex structures and special properties, and contribute to the development of materials science.
In the process of drug development, because it contains special functional groups, or endows the synthesized drugs with unique pharmacological activities, such as better targeting and higher bioavailability, it brings hope for the creation of drugs to overcome difficult diseases.
Furthermore, in the cutting-edge field of chemical research, as a research object, it can help researchers to deeply explore basic chemical problems such as organic reaction mechanism and stereochemistry, and promote the theoretical development and technological innovation of chemistry. Overall, this compound has indispensable uses in many important fields and is of great significance to scientific progress and practical applications.
What are the preparation methods of (S) -5-Chloro-Alpha- (Cyclopropylethynyl) -2-Amino-Alpha- (Trifluoromethyl) -Benzenemethanol?
The preparation method of (S) - 5 - - α - ( cyclopropylethynyl) - 2 - amino - α - ( trifluoromethyl) - benzyl alcohol has been around for a long time, and with the changes of years, a variety of exquisite methods have been developed.
In the past, the commonly used method was to use specific halogenated benzene derivatives as starting materials. First, halogenated benzene is introduced into trifluoromethyl through a series of reactions. This step requires careful control of the reaction conditions. Due to the difficulty of introducing trifluoromethyl, the reagents and environmental requirements are strict. Then, at a specific location of the benzene ring, an amino group is added by clever organic synthesis methods. This process requires precise control of the reaction check point and reagent activity to prevent side reactions.
Furthermore, to obtain the key structure of cyclopropylacetynyl, the reaction path needs to be carefully designed. Cyclopropane derivatives often interact with acetylation reagents to generate intermediates containing cyclopropylacetynyl groups, which are then combined with modified benzene derivatives. This binding step requires finding suitable catalysts and reaction solvents to improve the reaction efficiency and product purity.
In addition, modern preparation methods often rely on transition metal catalysis to achieve precise synthesis. For example, the cross-coupling reaction catalyzed by palladium can efficiently form carbon-carbon bonds and carbon-heteroatomic bonds, which greatly improves the yield and selectivity of the target product. And in the reaction process, pay attention to the application of green chemistry concepts, and strive to reduce the generation of waste and improve atomic economy.
At the same time, chiral control is also the key to the preparation of (S) -configuration products. Chiral catalysts or chiral auxiliaries can be used to induce the reaction to generate products of specific configurations. During the reaction process, advanced analytical techniques, such as high performance liquid chromatography, nuclear magnetic resonance, etc., can be used to monitor the reaction progress and product purity in real time to ensure that the product meets the expected quality.
Looking at the various preparation methods, each has its own advantages and disadvantages, and the best method should be carefully selected according to the actual needs and conditions, so as to achieve the purpose of high-efficiency and high-quality preparation of (S) - 5 - chloropropyl - α - ( cycloethynyl) - 2 - amino - α - ( trifluoromethyl) - benzyl alcohol.
(S) -5-Chloro-Alpha- (Cyclopropylethynyl) -2-Amino-Alpha- (Trifluoromethyl) -Benzenemethanol What are the precautions during use?
(S) - 5 - - α - ( cyclopropyl ethynyl) - 2 - amino - α - ( trifluoromethyl) - benzyl alcohol. When using this substance, all kinds of matters must not be ignored.
First, safety is essential. This substance may have special chemical activity and is related to the risk of explosion, corrosion, toxicity, etc. In the place of operation, all kinds of protective equipment should be prepared, such as gas masks, protective gloves, goggles, etc., to ensure personal safety. And the operation must be well ventilated to prevent the accumulation of harmful gases.
Second, accurate access. Because it is a fine chemical, accurate dosage is crucial. When taking it, an accurate measuring tool must be used, and it must be strictly measured according to the experimental or production requirements. If the dosage is deviated, or the reaction results are very different, it will affect the product quality.
Third, store it properly. According to its physical and chemical properties, choose suitable storage conditions. Avoid high temperature, open flame, humid place, or need to be in a specific temperature and humidity environment to ensure its chemical stability and prevent deterioration or degradation.
Fourth, be familiar with the reaction. Before use, you must know the chemical reaction mechanism and conditions involved. Understand the influence of factors such as the proportion of reactants, reaction temperature, and duration on the results, in order to effectively control the reaction process and obtain the expected product.
Fifth, compliance disposal. Residual materials and waste after use cannot be discarded at will. They should be properly disposed of in accordance with relevant regulations and standards to prevent environmental pollution and ensure subsequent environmental and personal safety. In this way, this material can be used safely and effectively.