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Pentafluorobenzenesulfonyl Chloride

Pentafluorobenzenesulfonyl Chloride

Hongda Chemical

Specifications

HS Code

626162

Chemical Formula C6ClF5O2S
Molecular Weight 278.57
Appearance Colorless to pale yellow liquid
Boiling Point Around 180 - 185 °C
Density Data may vary, but typically in range for organic sulfonyl chlorides
Solubility Soluble in many organic solvents
Vapor Pressure Relatively low at room temperature
Reactivity Highly reactive, especially towards nucleophiles
Hazard Corrosive, can cause severe skin and eye burns

As an accredited Pentafluorobenzenesulfonyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100 mL of Pentafluorobenzenesulfonyl Chloride in a sealed, corrosion - resistant bottle.
Storage Pentafluorobenzenesulfonyl chloride should be stored in a cool, dry, well - ventilated area away from heat, ignition sources, and incompatible substances. It must be kept in a tightly - sealed container to prevent leakage. Due to its reactive nature, store it separately from bases, water - containing materials, and reducing agents. Follow all safety regulations for handling and storage of such corrosive and reactive chemicals.
Shipping Pentafluorobenzenesulfonyl chloride, a hazardous chemical, must be shipped in accordance with strict regulations. It should be in a well - sealed, corrosion - resistant container, labeled clearly, and transported by carriers licensed for such chemicals.
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Pentafluorobenzenesulfonyl Chloride Pentafluorobenzenesulfonyl Chloride
General Information
Historical Development
In the field of chemical industry, there is a thing called Pentafluorobenzenesulfonyl Chloride. Its beginning is due to the research of the sages. At the beginning, the knowledge was fresh, and it only existed in the study of the Fang family. However, as the years passed, the workers studied hard, and its nature and use gradually became clear.
First, it was difficult to make, the production was rare, and the price was high, and it was only used for rare research. Later, the technique gradually refined, the method gradually improved, and the production increased. It has emerged in the fields of medicine and materials. What was difficult to make in the past has now become a widely used thing. From little known to manifest in various industries, this is the way of its development. Although it was difficult in the past, with the determination of the people and the progress of the art industry, it has achieved today's prosperity. Those who come later should follow this ambition, push its new use, expand its broad path, and shine the brilliance of chemical industry.
Product Overview
Pentafluorobenzenesulfonyl chloride is an important reagent for organic synthesis. Its color is colorless to light yellow liquid, with pungent odor and lively properties.
This product has a wide range of uses in the field of organic synthesis. It is often used as a sulfonylation reagent. It can introduce pentafluorobenzenesulfonyl groups to help build a variety of organic compound structures. It can react with many compounds such as alcohols and amines to generate corresponding sulfonyl esters and sulfonamides.
Because of its fluorine-containing atoms, it endows the product with unique properties, such as improving chemical stability and changing electron cloud distribution. In the fields of medicine and materials science, the reaction of pentafluorobenzenesulfonyl chloride may create new substances with special properties.
Although it is lively, extra caution is required during operation to prevent adverse reactions caused by improper contact with water, alkali and other substances. When storing, it should be placed in a cool, dry and well-ventilated place.
Physical & Chemical Properties
In the case of pentafluorobenzenesulfonyl chloride, its substance has special physicochemical properties. Looking at its shape, it may be a colorless to slightly yellow liquid at room temperature, clear and translucent, like the clarity of autumn dew. Its smell is pungent, and it smells like a needle into the nose, making it unbearable.
As for its boiling point, it is about a certain range, which is the critical point of gasification. Its density is different from that of normal substances, and it is heavier than water. It sinks in water and does not float. As for its solubility, it is soluble and miscible in many organic solvents, such as alcohols and ethers, but insoluble in water, like oil and water, which are distinct.
And the chemical activity of this substance is quite high, and it is easy to react when it encounters alkali, and the sulfonyl chloride group changes to form a salt of sulfonic acid. It has a wide range of uses in organic synthesis and is a good material for chemical preparation.
Technical Specifications & Labeling
Pentafluorobenzenesulfonyl chloride is an important product in the chemical industry. Its process specifications are related to the quality. When preparing, the proportion of materials, the temperature and duration of the reaction are all key. It must be precisely controlled to ensure a smooth reaction.
The standard of inspection is related to the purity of the product. Looking at its color, it should be pure and free of impurities. Measure its purity, when it reaches a very high standard. The content of impurities must be strictly limited. In this way, it is a qualified product.
Pentafluorobenzenesulfonyl chloride is useful in many fields. However, the process specifications and testing standards cannot be slack. Only by strictly observing its regulations can we obtain high-quality products to meet the needs of all parties.
Preparation Method
Pentafluorobenzene sulfonyl chloride is an important agent in organic synthesis. The method of its preparation is related to the raw material and production process, reaction steps, and catalytic mechanism, which cannot be ignored.
To prepare this substance, pentafluorobenzene is often used as the initial raw material, supplemented by chlorosulfonic acid. The two are mixed, and at a specific temperature, the temperature is controlled, and the reaction is slowly stirred. The reaction proceeds in sequence, the first is electrophilic substitution, and the sulfonic acid group enters the pentafluorobenzene ring to form pentafluorobenzene sulfonic acid. Then, at the place of sulfoxide chloride, the hydroxyl group is easily chlorine, and then pentafluorobenzene sulfonyl chloride is obtained.
The An appropriate amount of catalyst can reduce the activation energy, promote molecular collision, and increase the frequency of the reaction. The order of the reaction steps is also heavy. First stabilize the sulfonic acid, then chlorinate, do not be impatient and do not mess. The purity of raw materials and the appropriate proportion are the basis for the quality and quantity of the product. In this way, the best system is obtained.
Chemical Reactions & Modifications
I tried to study the reaction and modification of pentafluorobenzenesulfonyl chloride. The reaction of this compound is very complicated, and its properties also have variable domains.
At first, pentafluorobenzenesulfonyl chloride reacts with various substances, such as when it encounters with alcohols, it often forms esters. Its reaction speed depends on the genus of temperature and catalyst. In the past, the reaction rate was not perfect, and the secondary reaction occurred frequently.
Then think about the way of modification. After many tests, it was found that the addition of a certain agent can change the way. Under suitable temperature and pressure, the selectivity of the reaction is greatly increased, and the secondary reaction is reduced. And the stability of its substances also changes, and it can be more stable in various environments.
Although progress has been made in the synthesis and modification of pentafluorobenzenesulfonyl chloride, there are still unknowns. It is still necessary to study diligently to obtain better methods and make the best use of them.
Synonyms & Product Names
Today there is a thing called Pentafluorobenzenesulfonyl Chloride. There are many names and aliases. This chemical thing may have different names in the industry.
Or because of its characteristics, uses, or differences in origin and production methods, it is also known as the same thing.
Its commercial name, or due to marketing activities and product positioning needs, is also known as another name.
Although the names are different, they all refer to this Pentafluorobenzenesulfonyl Chloride. Looking at its various names, it is just like the stars, although each has its own appearance, it actually belongs to the same place, all of which identify this unique chemical product.
Safety & Operational Standards
In the case of pentafluorobenzenesulfonyl chloride, chemical substances are also included. It is crucial to the safety and operation specifications of this substance.
It is active, highly corrosive and irritating. During operation, protective equipment must be worn, such as protective clothing, protective gloves and goggles, to prevent skin and eyes from touching it. And the operation should be done in a well-ventilated place or in a fume hood to prevent its volatile gas from entering the body.
When storing, keep it in a cool, dry and well-ventilated place, away from fire and heat sources. Do not mix with alkalis, alcohols, etc., to prevent chemical reactions. When handling, be sure to pack and unload lightly to avoid leakage due to damage to its container.
If it is unfortunate to leak, quickly evacuate the surrounding people and set up an isolation area. Emergency responders need professional protective equipment and do not touch it directly. Small leaks can be adsorbed with inert materials such as sand and vermiculite and collected in a closed container. If a large amount of leakage, it is necessary to build a dike or dig a pit for containment, transfer it to a tanker or a special collector with a pump, and recycle or dispose of it harmlessly.
During use, also strictly abide by the operating procedures, do not use in excess, and make a record. After the experiment, properly dispose of the remaining items and do not discard them at will. Only in this way can the operation be safe and accidents can be avoided.
Application Area
Pentafluorobenzenesulfonyl chloride is a chemical substance, and its application field is wide. In the field of organic synthesis, it can be a powerful sulfonation reagent. With its high activity, it can react with many substrates to obtain various compounds containing sulfonyl groups. These compounds play a huge role in the creation of medicine and pesticides.
In the field of material science, pentafluorobenzenesulfonyl chloride participates in the synthesis of polymers with unique properties. Or increase its chemical stability, or change its electrical properties, it can be used to manufacture high-end electronic materials and special functional coatings.
Furthermore, in the field of surface modification, treating the surface of the material with this material can give the material specific surface properties, such as hydrophobic, oil-repellent, etc., which are used in the preparation of self-cleaning materials and anti-fouling coatings. Therefore, pentafluorobenzenesulfonyl chloride plays an indispensable role in many fields.
Research & Development
In the field of chemical industry, new products emerge one after another. Pent afluorobenzenesulfonyl Chloride is also the object of our dedicated research. Its unique nature seems to contain the wonders of creation. We investigate its essence, explore its origin, and want to understand its effectiveness in various reactions.
At the beginning, analyze its structure, observe its bonding, and see its essence. Then, try various conditions, observe the change of its reaction, or temperature or pressure, or add various agents, hoping to obtain the best method to promote its efficient generation.
The road to research is not smooth. There are many problems, such as the impure reaction, the yield is not as expected. However, we are not discouraged, repeated research, easier strategies, and unremitting progress.
With time, we have obtained a complete method, so that this Pent afluorobenzenesulfonyl Chloride product, both abundant and pure. Then it can be widely used in the fields of medicine and materials, to develop its talents, to help the industry's prosperity, and the advancement of science and technology. This is our grand wish for research and exploration.
Toxicity Research
Nowadays, there is a substance, named Pentafluorobenzenesulfonyl Chloride, which is important for our generation to study toxicology. This chemical substance, its nature is unknown, or contains toxic substances. Looking at its structure, it is a genus of pentafluoride, connected to sulfonyl chloride, or has special chemical properties.
To demonstrate its toxicity, various tests should be conducted. Take animals as tests, observe the changes in body shape and behavior after ingesting this substance, and the appearance of viscera functions. Observe whether it has any symptoms of discomfort, such as vomiting, fatigue, body weight loss, etc. It is also necessary to detect its damage to the organs, liver, kidneys, lungs, and whether there are signs of disease.
And study whether the residual and transformed state of this substance in the environment will accumulate in water and soil, and then harm organisms. In this way, we can know the toxicity of Pentafluorobenzenesulfonyl Chloride, and provide evidence for protection and application to ensure the safety of people, things and the environment.
Future Prospects
Wuguan pentafluorobenzenesulfonyl chloride has unique properties and great potential in the field of chemical industry. Although it is not widely used today, the future prospects are limitless.
This material is lively and can be used to create novel compounds, which can be used in the process of pharmaceutical research and development, or can be the key to finding effective medicines. It is also expected to emerge in materials science and create new materials with excellent performance, such as those with extraordinary weather resistance and anti-corrosion characteristics.
Our generation of chemical researchers should study it carefully, explore its subtlety, and tap its potential. Over time, pentafluorobenzenesulfonyl chloride will be able to shine, demonstrate its exceptional value in various industries, and pave the way for future development.
Where to Buy Pentafluorobenzenesulfonyl Chloride in China?
As a trusted Pentafluorobenzenesulfonyl Chloride manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading Pentafluorobenzenesulfonyl Chloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the physical properties of pentafluorobenzenesulfonyl chloride?
Wuhe realgar is the essence of pure yang. It is strong and toxic in nature. It has the functions of drying dampness and removing phlegm, killing insects and detoxifying, chasing cold to remove dampness, and cutting malaria. Its color is as beautiful as a chicken crown, the quality is brittle and the body is light, and it turns into powder when studied.
Realgar is born in the yang of mountains, collected in the land of five rivers, and obtains the qi of pure yang in heaven and earth, and contains the essence of mountains and rivers. Its nature is strong, and it burns when it encounters fire. Smoke and odor are produced. This is its great nature.
In the way of medicine, realgar can dry dampness and remove phlegm, so that the evil of dampness does not gather, and phlegm and saliva can be melted. Repels cold and removes dampness, makes cold evil escape far away, and dampness evil dissipates. The effect of cutting malaria is particularly peculiar, which can slow down the disease of malaria.
However, realgar is poisonous, so use it with caution. If you take it too much, it may cause poisoning, and if it is light, your head will be dizzy, and if it is serious, your life will be endangered. When using it externally, you should not apply it on a large area to prevent its poison and evil from invading.
Therefore, although realgar has many wonderful physical properties, those who use it must carefully examine its nature, abide by the law, and weigh the pros and cons. Only then can they do their best to avoid its harm, protect their health, and do not make poison evil a disaster.
What are the chemical properties of pentafluorobenzenesulfonyl chloride?
The blue mist in the five rivers of the sea is quite unique in its chemical properties. The water quality of the five rivers where this fish is located is specific, which makes it have different chemical characteristics.
First, the body of the sea fish is rich in trace elements. Under the nourishment of the water and soil of the five rivers, the sea fish absorbs many trace elements in the water, such as iron, zinc, selenium, etc. Iron is involved in the transportation and storage of oxygen in the sea fish, which is related to its respiration and energy metabolism. Zinc is a component of various enzymes and plays an important role in the growth, immunity and reproduction of the sea fish. Selenium has antioxidant effects, which can protect the cells of the sea fish from free radical damage and maintain the normal physiological function of the body.
Second, the mucus on the surface of the fish contains special chemical components. This mucus not only reduces the resistance of the fish to swim in the water, but also has certain antibacterial and antiviral properties. Studies have shown that the mucus contains a variety of bioactive substances, such as mucopolysaccharides and proteins. Mucopolysaccharides can regulate immune function and enhance the resistance of the fish to diseases; protein plays a key role in maintaining the structure and function of the mucus.
Third, the chemical composition of the muscles of the fish also has characteristics. Its muscles are rich in high-quality protein, and the composition of amino acids is reasonable, which meets the nutritional needs of the human body. At the same time, the fat content in the muscles is moderate, and most of them are unsaturated fatty acids, such as oleic acid and linoleic acid. These unsaturated fatty acids are beneficial to human cardiovascular health, can reduce blood lipids and prevent cardiovascular diseases.
Furthermore, the enzymes in the body of the bark also have special chemical properties. Many digestive enzymes, metabolic enzymes, etc. play an indispensable role in the process of digesting food, obtaining energy and maintaining physiological balance in the bark. Its activities and characteristics are affected by the ecological environment of Wuhe, and adapt to local food sources and living conditions.
In summary, the chemical properties of the blue mist of Wuhe bark are diverse and unique, which not only stem from the unique water environment in which it grows, but also have an important impact on its survival and edible value.
In which fields is pentafluorobenzenesulfonyl chloride used?
The sea serpent of the five lakes is often used in the remote mountains and seas, and in the deep realm of the river.
The mountains and rivers of Fu, the secluded places of the forest, are often like elephants. The sea serpent of the five lakes is a place of seclusion, and it is also a place of seclusion. In the depths of the mountains, ancient trees are in the sky, and vines are intertwined, where people are rarely able to go, and it is an occasional place. It is diffuse, there is light in the sky, like fantasy and reality, like the sky. Practitioners in the mountains may be able to meet them, with auspicious omens, which can help them to clear and understand the wonders of the sky and the earth.
And on the banks of the big mountains, the marsh is muddy, the water is vast, and the realm of ordinary people, the sea serpent of the five lakes may also be reduced. Here, the surface of the water is covered by the sea, and the water light shines on each other, as if it were an illusion. Some people may have to use it as a warning or protection from the gods.
In addition, the sea is lonely overseas, and the fire of the people is also often shipped. The strange rocks on the sea are jagged, and the coconut forest is swaying, and it is like a fairy mountain, and it is at the end of the sea. Seafarers have sailed here, looking at the sea in the middle of the sea, often looking at the immortals, and their hearts are headed for it, or they are angry because of fear.
In short, the Five Lakes Sea Serpent is mostly used in places where people are scarce and nature is quiet, where the world is sympathetic, and it attracts people's reverie and awe of the unknown world.
What is the preparation method of pentafluorobenzenesulfonyl chloride?
The method of the five beams is to carefully select the good ones. The first one to do so is to remove the good ones, such as panning for gold in the sand, making the good ones, and the foundation of the square.
Its smelting is good, and the heat is essential. With a suitable heat, the heat will be melted without burning, just right. It is not advisable for the fire to be weak and the fire to be easy to burn. When it melts into a liquid, such as red gold flowing, the heat will be heavy and prevent the dust from falling.
Connect the next shape. The first fine mold is made, and the shape and flower of the mold are all determined according to the desired pattern. Melt the mold into the mold, do it properly and slowly, so that the liquid is evenly distributed, and fill in the mold. If there is a bubble, it can be drawn out by the method, so as not to have flaws in the mold.
Wait for it to cool, this process can't be rushed. Slowly cold, so that the mold can be set slowly, so that it can be solid and durable. Cold, be careful of the mold, the shape of this mold has been formed, but it still needs to be polished.
The work of polishing, especially the heart. Use the appropriate tools to rub, first remove the hair, and then make the surface as smooth as ice. The grinding force should be uniform, and it should not be biased, so that the surface is flat and bright, and the reflection is clear, so that it can illuminate people's eyebrows and eyes, and you are done. In this way, the five beams are completed, which can be used by people to reflect the posture of objects.
What should be paid attention to when using pentafluorobenzenesulfonyl chloride?
Five Ocean Immortal Grass Spiritual Liquid, this is a rare thing. When using it, many matters need to be paid attention to.
The choice of the first time. Between heaven and earth, yin and yang are orderly, and the five elements circulate, all following the time. Use it when you choose good luck, in order to conform to the times of the sky, and use the spiritual energy of heaven and earth to help its medicinal effects flow smoothly. Looking at the sky, the dawn is just beginning to dawn, the yang energy is gradually rising, and all things are recovering. This is the beginning of the day, full of vitality, which can be used to attract yang qi into the body, smooth qi and blood and stimulate the spirit; or on the night of the full moon, the moon is as bright as water, and the yin qi is full. Use it to absorb the effect of yin and moisturize, and it is better to Do not use it when the yin and yang are confused, the wind and rain are dark, so as not to take advantage of the evil energy to enter and cause disaster.
Furthermore, you must cleanse your body and mind before use. If the body is clean, there will be no obscene interference, and if the mind is clean, there will be no distractions. First bathe in fragrant soup, wash the dust, and remove all kinds of uncleanness from the body. Then in the quiet room, sit upright, abandon the troubles of the world, and make the mind peaceful. If the mind is distracted and distracted, even the fairy grass spiritual liquid will be difficult to do its best.
The dosage used must be accurate. The medicinal power of this spiritual liquid is mellow, and it is comparable to something unusual. If it is too much, it may cause qi and blood rebellion, and damage to the viscera; if it is less effective, it will be difficult to show, and it will be a waste of treasures. When following the doctor's advice, or according to the experience passed down by predecessors, the appropriate dose should be determined. And do not increase or decrease without authorization, so as not to cause serious trouble.
You also need to recuperate after use. The diet should be light, and avoid spicy and thick-tasted, cold and greasy things, so as not to hurt the spleen and stomach and hinder the medicinal power. Living should be regular, go to bed early and get up early, avoid overwork, so that the body can rest and recuperate, so that the effect of fairy grass and spiritual liquid can slowly nourish the whole body and achieve the purpose of strengthening the body and prolonging life