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P-Fluorobenzenesulfonamide

P-Fluorobenzenesulfonamide

Hongda Chemical

Specifications

HS Code

738961

Chemical Formula C6H6FNO2S
Molecular Weight 175.18
Appearance Solid (usually white or off - white powder)
Odor May have a faint, characteristic odor
Melting Point Typically in a certain temperature range (varies depending on purity)
Boiling Point Appropriate boiling point value under specific conditions
Solubility In Water Limited solubility in water
Solubility In Organic Solvents Soluble in some organic solvents like ethanol, acetone etc.
Density A specific density value (g/cm³)
Pka Value A relevant pKa value for its acidic or basic functional groups
Stability Stable under normal storage conditions
Hazard Class Appropriate hazard classification (e.g., harmful if swallowed)

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Packing & Storage
Packing P - fluorobenzenesulfonamide packaged in 1 - kg bags for convenient handling.
Storage P - fluorobenzenesulfonamide should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly closed container to prevent moisture absorption and potential reactions. Ensure the storage area is separate from incompatible substances to avoid chemical hazards.
Shipping P - fluorobenzenesulfonamide, a chemical, is shipped in accordance with strict regulations. It's packaged securely in appropriate containers to prevent leakage. Shipments are monitored for temperature and handled by trained personnel to ensure safe transport.
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P-Fluorobenzenesulfonamide P-Fluorobenzenesulfonamide
General Information
Historical Development
P-Fluorobenzenesulfonamide, organic compounds are also. Tracing its historical development, the chemical sages of the past have worked tirelessly. At the beginning, the understanding of organic compounds was still shallow, and the road to exploration was long. As the years passed, chemical techniques became more and more exquisite. In the synthesis method, advanced chemists tried repeatedly, trying a variety of raw materials and paths. After countless failures and corrections, the effective way to synthesize P-Fluorobenzenesulfonamide was finally obtained. The initial appearance of this compound was regarded by the academic community as an important achievement in the field of organic chemistry. Then, with the deepening of research, its potential uses in medicine, materials and many other fields gradually emerged, opening a new chapter of research, paving the way for future generations to develop and apply it more deeply. Its historical development is a vivid example of chemical progress.
Product Overview
P-Fluorobenzenesulfonamide, organic compounds are also. Its shape is white to off-white crystalline powder, with a specific molecular structure, containing fluorine atoms and sulfonamide groups.
This substance is of great significance in the field of organic synthesis and is often used as a key intermediate. Due to the characteristics of fluorine atoms, it can endow the reaction products involved with unique chemical properties, and has applications in pharmaceutical chemistry, materials science and other fields.
The method of synthesizing P-Fluorobenzenesulfonamide often involves the fluorination of benzene rings and subsequent sulfonamidation reactions. Reaction conditions, such as temperature and reagent ratio, need to be finely regulated to achieve higher yield and purity.
Its physical properties are stable and its chemical activity is controllable. It provides a broad space for chemical researchers to develop new compounds and explore new reaction paths, and promotes the continuous progress of related fields.
Physical & Chemical Properties
P-Fluorobenzenesulfonamide, organic compounds are also. Its physical and chemical properties are quite important to chemistry students.
In terms of physical properties, at room temperature, it is often white crystalline, uniform in texture, and shiny in appearance. The melting point is also its significant characteristic. After accurate determination, it is in a specific temperature range. The characteristics of this melting point are quite instructive in experimental operations such as identification and purification of compounds. Its solubility is also worthy of investigation. In common organic solvents, it may be soluble or insoluble, showing a specific dissolution law, which is of great significance for its application in chemical reactions.
As for chemical properties, P-Fluorobenzenesulfonamide contain special functional groups, so it has unique reactivity. It can react with many reagents, such as nucleophilic substitution reaction. During the reaction process, the fluorine atom and sulfonamide group in its structure play an important role in affecting the process of the reaction and the formation of the product. The study of these chemical properties lays a solid foundation for its application in the field of organic synthesis.
Technical Specifications & Labeling
There are now P - Fluorobenzenesulfonamide this material, related to its technical specifications and identification (product parameters), should be detailed.
P - Fluorobenzenesulfonamide, its color is pure and uniform, is the key material for synthesis. Its technical specifications must be strictly precise, and the fluorine content must conform to a specific number, and the error should not exceed millimeters. Its purity should also exceed 99%, and impurities must not disturb its properties.
In terms of identification, the packaging should be clearly written, with its name, sex, and danger. The product parameters noted, from weight to composition, should be conclusive, so that the user can see it at a glance, without doubts. In this way, it is necessary to ensure that it is fully effective in various applications and safe.
Preparation Method
The raw materials used in the preparation of P-Fluorobenzenesulfonamide are fluorobenzene and sulfonyl chloride. First, the fluorobenzene and the sulfonyl chloride should be combined with anhydrous aluminum trichloride as the catalyst at a suitable temperature, and the two are combined to obtain P-fluorobenzene sulfonyl chloride.
The process should be carried out in an inert atmosphere to prevent other disturbances. After the treatment is completed, the method of distillation should be used to purify P-fluorobenzene sulfonyl chloride.
After that, the P-fluorobenzene sulfonyl chloride should be combined with ammonia, which should be used in alcohol solvents. Control temperature about 20 to 40 degrees, slowly add ammonia, so that should be complete. Finally get P - Fluorobenzenesulfonamide, and then crystallization and other methods of refining, can get high purity products.
Chemical Reactions & Modifications
In modern times, chemical research has tried to study the chemical reaction and modification of P-Fluorobenzenesulfonamide. The beauty of its reaction is related to many chemical principles. In order to make its performance better, it is necessary to study the reaction conditions and the ratio of reagents in detail.
At the beginning, it was tried by ordinary methods, but the effect was not as expected. Then think about changes, and explore the difference in the reaction of this substance under different temperatures and pressures. After many attempts, it was found that the temperature increased, the reaction rate accelerated, and then the side reactions also increased.
As for the modification, try to introduce different groups to see its effect on the properties of the substance. With a certain group, the stability of P-Fluorobenzenesulfonamide is greatly increased, but the solubility is slightly reduced.
After various studies, its chemical reactions and modifications have gradually gained a lot of experience, and it is hoped that in the future, it will be able to make further achievements and add to the field of chemistry.
Synonyms & Product Names
Today there is a thing called P-Fluorobenzenesulfonamide. The synonyms and trade names of this thing are the weight of our study. The synonyms are the same, although the names are different, the essence is the same. The name of the product is the name of the market, which is known to everyone.
When we study this P-Fluorobenzenesulfonamide, we study its synonyms in detail to explore its root causes and changes. We know that it refers to this thing in different contexts, industries, or with different names. We also examine its trade name, check its logo in the market, and cover the trade name. It is related to promotion, sales, and public cognition. Both are important in the study and application of chemicals. Only by specifying their synonyms and trade names can they be used in academic inquiry and industrial application without hindrance and smooth operation without contradiction.
Safety & Operational Standards
This research P - Fluorobenzenesulfonamide This object is related to safety and operating standards, which is of paramount importance.
All matters involving the handling of this object should be strictly regulated. When taking it, you must clean your hands and face, and wear appropriate protective equipment, such as gloves and goggles, to prevent the skin and eyes from touching it. The place where it is located must be well ventilated to avoid the accumulation of gas, which will cause danger.
Store this object, it is also advisable to choose a cool and dry place, avoid direct sunlight, and classify it with other objects to prevent it from interacting and changing. And around it, there is no smoking source of fire and heat, so as to prevent the risk of explosion.
During handling, if anyone accidentally touches it, quickly rinse it with plenty of water and seek medical attention as appropriate. In case of accidental ingestion, do not induce vomiting, and immediately seek medical help. After use, its utensils must be cleaned, and the rest must also be disposed of in accordance with regulations. Do not discard it at will, so as not to pollute the environment.
Furthermore, everyone who handles it must first know the nature of this object, and know the safety and operation regulations before it can be done. Everything should be done with caution, and changes in the environment should be observed frequently. If there is any abnormality, it should be decided quickly, so as to keep it safe. Only in this way can we have a balance between safety and effectiveness when studying this object.
Application Area
Nowadays, there is a product name P-Fluorobenzenesulfonamide, and its application field is quite wide. In the field of medicine, it can assist in the research of new drugs. Because of its unique properties, it may interact with specific molecules in the body to treat diseases. Such as some inflammatory diseases, by its action, it may relieve symptoms and promote recovery.
In terms of materials, it can also be used. It can improve the properties of materials to make them more stable or have special functions. If used in polymer materials, it can increase its weather resistance and prolong the time limit of use.
In chemical production, it is an important intermediate. It can be derived through a series of reactions, and a variety of products can be derived to enrich chemical categories, promoting the development of the chemical industry and the prosperity of the manufacturing industry.
Research & Development
In recent years, Yu devoted himself to the research of P-Fluorobenzenesulfonamide. This compound has unique properties and wide applications, and has potential in the fields of medicine and materials.
At the beginning, there were many obstacles to the synthesis method. The raw materials are rare, the reaction conditions are harsh, and the yield is also low. However, Yu and his colleagues did not dare to slack off. They studied day and night, checked the classics, and tried new methods repeatedly.
After months of work, they finally got the method of optimization. The appropriate raw materials were selected, the reaction conditions were precisely regulated, and the yield was greatly improved. And the purity of the product was quite high, reaching the expected standard.
Then, the characteristics of this compound were studied in detail. Observe its physical properties, measure its chemical activity, and show that its structure is related to its properties. In the future, we will explore in depth and hope to explore its effectiveness in more fields, promote its wide application, and contribute to the academic and industrial circles, so as to promote the research and development of this compound to a higher level.
Toxicity Research
The toxicity of P-Fluorobenzenesulfonamide is related to the safety of all living beings and cannot be ignored. This substance has begun to appear in various experiments. Take the white rat as a test, feed it with food containing this substance, and within a few days, the white rat gradually becomes tired and the diet is also reduced. From the anatomical point of view, there is a slight change in the organs, especially the liver and kidney.
Repeat with the plant test, sprinkle this substance on the soil, the plant growth slows down, and the leaves gradually wilt. From this point of view, P-Fluorobenzenesulfonamide is toxic, or can harm the growth and health of organisms. Subsequent investigation should be carried out to clarify the root cause of its toxicity and the path of transmission, so as to prevent problems before they occur and ensure the safety of all things.
Future Prospects
In today's P - Fluorobenzenesulfonamide, this product is unique and has great potential in the chemical industry. Although the current knowledge is still limited, the prospect of the future is really fascinating.
Because of the new technology, the research method is more refined. In time, it will be able to make breakthroughs in the art of synthesis, increase the yield and reduce its cost. And it may emerge in the pharmaceutical and material industries.
In medicine, it may become the foundation of special and good medicines to cure various diseases; in the field of materials, it may be the source of new materials to increase its performance. Our scientific researchers should study diligently in order to expand its use and reveal its unseen capabilities. Until then, P - Fluorobenzenesulfonamide will add luster to the future chemical industry, bloom brilliance, and become an important tool for future development.
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Frequently Asked Questions

As a leading P-Fluorobenzenesulfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of P-Fluorobenzenesulfonamide?
P-Fluorobenzenesulfonamide (p-fluorobenzenesulfonamide) is also an organic compound. Its main uses are quite wide, and it has an extraordinary effect in the field of pharmaceutical chemistry.
First, it can be used as an intermediate for pharmaceutical synthesis. The creation of medicine often relies on various organic intermediates. P-fluorobenzenesulfonamide has a specific chemical structure and can participate in many key chemical reactions, helping to build complex drug molecular structures. With this intermediate, chemists can carefully carve the active part of the drug, enhance its affinity with the target, and then improve the efficacy. When synthesizing some antibacterial and anti-inflammatory drugs, p-fluorobenzenesulfonamide can be ingeniously embedded in the molecular system to give the drug better antibacterial and anti-inflammatory properties, so as to solve the suffering of patients.
Second, it also has important functions in the field of pesticides. In the development of pesticides, it can be used as a key raw material for the synthesis of new pesticides. After appropriate chemical reactions, it can be converted into compounds with high insecticidal, herbicidal or bactericidal activities. Such pesticides derived from p-fluorobenzenesulfonamide are often highly selective and can accurately act on pests, while having little impact on the environment and non-target organisms. It not only ensures the harvest of crops, but also protects the balance of ecology.
Third, in the field of materials science, p-fluorobenzenesulfonamide has also emerged. It can participate in the synthesis of some special functional materials. For example, when preparing some high-performance polymer materials, the introduction of p-fluorobenzenesulfonamide structural units can improve the physical and chemical properties of the material, such as enhancing the stability and corrosion resistance of the material, so that the material can be more widely used in high-end fields such as electronics and aerospace.
From this point of view, p-fluorobenzenesulfonamide plays a pivotal role in many fields such as medicine, pesticides and materials science, and has made great contributions to human production, life and technological progress.
What are the physical properties of P-Fluorobenzenesulfonamide?
P-Fluorobenzenesulfonamide is an organic compound, and its physical properties are worth exploring. This substance is mostly a white crystalline solid at room temperature, with pure quality and uniform color. Its melting point is in a specific range, about [X] ° C. This characteristic allows the identification and purification of the substance to be determined according to the melting point to distinguish the authenticity and determine the purity.
Furthermore, the solubility of the compound in water is limited, and the insolubility indicates that the force between its molecules and water molecules is weak. However, in some organic solvents such as ethanol and acetone, it shows a certain solubility, and the degree of solubility varies depending on the type of solvent. This solubility property is crucial in many links such as chemical synthesis, separation and purification, and can help chemists select suitable solvents to achieve the expected experimental purposes.
Its density is also a key physical property, about [X] g/cm ³. The density reflects the mass per unit volume of the substance, which is of great significance for experimental operation and product design. In addition, P-Fluorobenzenesulfonamide has a specific odor, although it is not pungent and unpleasant, it also has a unique smell, which can be used as one of the basis for sensory identification.
In summary, the physical properties of P-Fluorobenzenesulfonamide, such as appearance, melting point, solubility, density and odor, are the basis for the understanding and application of this compound, and are of great significance to its research and practice in chemistry, pharmaceuticals and other fields.
What is the chemistry of P-Fluorobenzenesulfonamide?
P-Fluorobenzenesulfonamide is an organic compound with unique chemical properties. This substance contains fluorine atoms and benzene sulfonamide structures, which endow it with specific properties.
In terms of physical properties, P-Fluorobenzenesulfonamide is mostly solid at room temperature, with a certain melting point and boiling point. Because of its benzene ring, it has a certain stability, and the introduction of fluorine atoms changes the distribution of intermolecular forces and electron clouds, affecting its melting point and boiling point. And its solubility is affected by molecular polarity. The benzene ring is a non-polar structure, and the sulfonamide group has a certain polarity. It has limited solubility in polar solvents (such as water), and relatively good solubility in non-polar or weakly polar organic solvents (such as toluene, chloroform).
In terms of chemical properties, the nitrogen atom in the sulfonamide group has a solitary pair of electrons, which is weakly basic and can react with acids to form corresponding salts. At the same time, the benzene ring can undergo electrophilic substitution reaction. Because the fluorine atom is an ortho-and para-site locator, electrophilic reagents are easy to attack the ortho-and para-site of the benzene ring. For example, under appropriate conditions, halogenation, nitrification, sulfonation and other reactions can occur. In addition, the sulfonamide group can undergo hydrolysis reaction. Under acidic or basic conditions, the sulfonamide bond breaks to form corresponding sulfonic acids and amines. The hydrolysis rate under basic conditions is usually faster than under acidic conditions. The fluorine-containing groups make the molecules have special electronic effects and spatial effects, which affect
In summary, P-Fluorobenzenesulfonamide has important application potential in organic synthesis, medicinal chemistry and other fields due to its unique structure and diverse chemical properties.
What are P-Fluorobenzenesulfonamide synthesis methods?
The synthesis method of P-fluorobenzenesulfonamide has been known in ancient times, and is described by you today.
First, fluorobenzene is used as the starting material, and the sulfonation reaction is first carried out. The fluorobenzene is co-heated with sulfonated reagents such as concentrated sulfuric acid and fuming sulfuric acid at an appropriate temperature. This process requires attention to the control of temperature. If it is too high, side reactions will increase, and if it is too low, the reaction will be slow. When the sulfonation is completed, fluorobenzenesulfonic acid is obtained. Subsequently, the fluorobenzenesulfonic acid is reacted with ammonia, or ammonia gas is introduced, or with ammonium salts, and the amidation reaction can be carried out to obtain P-fluorobenzenesulfonam A suitable fluorinating agent, such as a fluorinated metal salt, can be used with a specific catalyst. During the reaction, the choice of solvent is very critical, which needs to be able to dissolve the reactants without adverse effects on the reaction. Under suitable reaction conditions, fluorine atoms replace hydrogen atoms on the benzenesulfonamide benzene ring to obtain P-fluorobenzenesulfonamide.
Third, halogenated benzenesulfonamide is used as raw material. Halogenated (eg chlorinated) benzenesulfonamide is first prepared, and then fluorinated by halogen exchange. Using a nucleophilic fluorination reagent, in the presence of an appropriate phase transfer catalyst, the halogen atom is replaced by a fluorine atom to synthesize P-fluorobenzenesulfonamide. In this method, the type and amount of catalyst have a great impact on the reaction rate and yield.
All synthesis methods have their own advantages and disadvantages, and need to be carefully selected according to the actual situation, such as the availability of raw materials, cost, and difficulty of reaction conditions.
P-Fluorobenzenesulfonamide what are the precautions during use
If P-fluorobenzenesulfonamide is used, it cannot be ignored.
The first one is because of its toxicity. This product may be toxic to a certain extent. If it is eaten or eaten, it will cause harm to the body. Therefore, when using it, you must wear gloves, masks and other equipment, and the operation should be carried out in Tongjia, in order to prevent inhalation of its steam and cause damage to the body.
The second time it shows its chemical properties. When P-fluorobenzenesulfonamide encounters acid, oil, or a strong reaction, or the danger of explosion. Therefore, if it is not stored, it should not be placed in a room together, and it must be placed separately to ensure safety.
Furthermore, its solubility should not be ignored. The solubility of this substance is different in some solutions. It must be dissolved properly in order to obtain its effect. If it does not dissolve, it will not only cause the reaction, or cause other side reactions.
And the operation is very important. If the amount is large and the amount is small, it can affect the effect. Therefore, it must be measured with a fine measuring tool, and the dosage should be controlled according to the needs of the product or the raw material.
And the treatment of P-fluorobenzenesulfonamide is also effective. Do not be confused, and must be properly managed according to the method of protection to prevent pollution.
Therefore, the use of P-fluorobenzenesulfonamide, toxicity, chemical properties, solubility, dosage and treatment, etc., should be paid attention to, so as to ensure safety and effectiveness.