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O-Trifluoromethyliodobenzene

O-Trifluoromethyliodobenzene

Hongda Chemical

Specifications

HS Code

641446

Chemical Formula C7H5F3I
Molecular Weight 286.01
Appearance Colorless to light yellow liquid
Boiling Point 196 - 198 °C
Density 1.84 g/cm³
Flash Point 80 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ether, chloroform
Vapor Pressure Low vapor pressure at room temperature
Stability Stable under normal conditions but may react with strong oxidizing agents

As an accredited O-Trifluoromethyliodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing O - trifluoromethyliodobenzene packaged in 500 - gram bottles for chemical use.
Storage O - trifluoromethyliodobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. It should be kept in a tightly - sealed container to prevent leakage and exposure to air and moisture, which could potentially cause degradation or dangerous reactions. Store it separately from oxidizing agents and incompatible substances.
Shipping O - trifluoromethyliodobenzene is shipped in specialized, well - sealed containers. Due to its chemical nature, it's transported in accordance with hazardous materials regulations, ensuring proper handling and safety during transit.
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O-Trifluoromethyliodobenzene O-Trifluoromethyliodobenzene
General Information
Historical Development
In the past, there were people who studied chemistry, specializing in one thing, called O-Trifluoromethyliodobenzene. The research and development of this thing has gone through years. At the beginning, everyone's understanding of it was still shallow, and the road to exploration was full of thorns. However, the wise men did not give up their research, or operated it day and night in the laboratory, and tried it with different methods. After repeated trials and corrections, they gradually gained something. With the passage of time, the technology has become more and more mature, and they have a deeper understanding of its nature and production method. People continue to improve their processes, so that their quality can be improved, and their output can also increase. Although this process is difficult, with their determination, the chemists finally made O-Trifluoromethyliodobenzene occupy a place in both academia and industry. Its development process can be described as a good story in the history of chemical exploration.
Product Overview
"Chemical Description"
There is a substance named O-Trifluoromethyliodobenzene. This substance has unique properties. Its shape may be liquid, color or clear.
From its composition, it contains fluorine, iodine, carbon and hydrogen elements. Fluorine is active and attached to molecules, giving this substance special chemical activity. Iodine atoms are also among them, increasing the diversity of its reactions.
View its use, in the field of organic synthesis, it is often a key reagent. It can introduce special groups into organic molecules to help form complex and delicate structures. In pharmaceutical research and development, or the creation of new drugs containing this structure, to meet the needs of disease treatment; in material science, or to lay the foundation for the synthesis of new materials, endowing materials with specific properties.
Although it has great uses, when operating it, be cautious. Because of its high chemical activity, or in combination with other things, it causes danger. Strict procedures must be followed to ensure safety and security, so as to make good use of this product for the advancement of science and technology and the benefit of people's livelihood.
Physical & Chemical Properties
There is a substance named O-Trifluoromethyliodobenzene. The physical and chemical properties of the substance are related to the research. Looking at its shape, at room temperature, or in a liquid state, it has a special color and taste. The genera of its boiling point and melting point are all characterized. The boiling point is related to the temperature of gasification, and the melting point is the degree of solidification.
In terms of chemistry, the existence of atoms such as fluorine and iodine in its structure makes it uniquely reactive. Fluorine atoms are highly electronegative, causing molecular electron clouds to diverge and easily react with nucleophiles. Although iodine atoms are more active, their reactivity in the structure of the substance is also affected by surrounding groups.
The physical and chemical properties of this substance have potential uses in various fields such as chemical engineering and materials, and need to be investigated in detail to clarify its properties and make the best use of it.
Technical Specifications & Labeling
Today there is a thing called O-Trifluoromethyliodobenzene. In terms of the technical specifications and identification (product parameters) of the thing, our generation needs to study it in detail.
Looking at its craftsmanship, we should follow the rules of precision. The selection of raw materials must be pure and flawless, and the content of impurities should not exceed the limit of trace amounts. The reaction conditions, temperature and pressure must be strictly controlled, and the difference of millimeters may cause changes in quality. The synthesis process, steps are well-organized, and the products of each step should meet the established standards.
As for the identification, the product parameters should be clearly identifiable. The proportion of the elements contained is accurate to the decimal place. Physical properties, such as color, state, and taste, must be recorded in detail. The key to chemical properties, stability, reactivity, etc., cannot be missed. In this way, this product can be used in the application, each appropriate, to show its ability, in line with everyone's requirements.
Preparation Method
In order to prepare O-Trifluoromethyliodobenzene, it is necessary to clarify its raw materials and production process, reaction steps and catalytic mechanism.
The precursor materials are mainly fluorine-containing reagents and iodine-substituted benzene compounds. The production process, the control of the first reaction environment, temperature, pressure and solvent are all key. The reaction steps take nucleophilic substitution or addition reaction as the diameter. If nucleophilic substitution is selected, the fluorine atom of the fluorine reagent attacks the specific check point of the iodine-substituted benzene, breaks the old bond and forms a new bond.
The catalytic mechanism is also important. The selection of a suitable catalyst can reduce the reaction energy barrier and promote the reaction rate. Such as metal catalysts, by means of their empty orbitals complexed with the reactants, the
When operating, follow the procedures, control the reaction process, and maintain the purity and yield of the product. In this way, a good method of O-Trifluoromethyliodobenzene is obtained.
Chemical Reactions & Modifications
Modern chemical refinement, in the research of various compounds, with each passing day. Today, O -Trifluoromethyliodobenzene this substance, and its chemical reaction and modification are quite important in the academic community.
In the past, to make O -Trifluoromethyliodobenzene, the reaction was difficult and the yield was not good. The method used often encountered obstacles, or the reaction conditions were harsh, or the side reactions were frequent, resulting in impure products.
After all the sages worked hard, the improved method gradually emerged. With the intervention of new catalysts, the reaction was mild and fast, and the yield was also increased. Or adjust the reaction medium to optimize the reaction path, and the quality and quantity of the product were improved. As a result, O -Trifluoromethyliodobenzene in various fields of application, but also because of the modification and wider, the wonderful chemistry, can be seen here, the future research, must be higher.
Synonyms & Product Names
I tried to study the technology of chemical industry, and in the field of organic, I came across a product named O-Trifluoromethyliodobenzene. This product has various different names, and its business name is also special.
O-Trifluoromethyliodobenzene, from its structure perspective, fluorine, iodine-based, fluorine-containing, active and has special physical and chemical properties, iodine is also an important element in organic synthesis. Its synonym, or according to its functional group position and structural characteristics, is the convenience of the identification of chemical products. The business name involves the market and production, so each producer may have different names.
We study this product to understand its nature and explore its use. In the process of organic synthesis, or as a key material, it helps to form new drugs and new materials. Therefore, the study of its different names and commercial names can communicate the context of the chemical industry, gather the knowledge of all parties, and promote the prosperity of this industry. Although the name is unique, the essence of natural things is the same, and it will be well used by our generation.
Safety & Operational Standards
There is a chemical product O-trifluoromethyl iodobenzene, which needs to be detailed in terms of its safety and operation specifications.
O-trifluoromethyl iodobenzene is a commonly used product in chemical research, but its properties are latent risk, so safe operation is essential.
Where this material is involved, the first place should be ventilated. Handle in a well-ventilated place to avoid the accumulation of harmful gases and ensure the safety of the experimenter. In addition, the experimenter must wear suitable protective equipment, such as gloves, goggles and lab clothes. The gloves should be resistant to chemical corrosion, the goggles can resist liquid splashing and damage the eyes, and the lab clothes can protect the body from harmful substances.
When operating, the movement should be steady and careful. When measuring this substance, use a precise measuring tool to control the amount to avoid waste and danger. During the transfer process, beware of spillage. If it is accidentally spilled, clean it up quickly according to the established process. Cover it with adsorbent first, and then collect the waste properly to prevent pollution to the environment.
There are also regulations for storage. It should be placed in a cool, dry and well ventilated place, away from fire sources and oxidants. Store it in categories, and avoid mixing with conflicting substances. Regularly check the storage status to see if the packaging is damaged or leaked.
After the experiment, the instrument must be washed. Remove residual O-trifluoromethyliodobenzene to ensure safe and accurate use next time.
When using O-trifluoromethyl iodobenzene, people strictly abide by safety and operating standards to avoid danger and promote the smooth progress of chemical research.
Application Area
Today there is a thing called O-Trifluoromethyliodobenzene. This thing has its uses in various fields.
In the field of medicine, it can be used as a raw material for creating new agents. With its unique structure, it can help doctors make drugs with special curative effects to treat various diseases and save patients from pain.
In the field of materials, it also develops its strengths. It can be used to synthesize materials with specific properties, or increase their stability, or give them new functions, making materials suitable for different scenarios, such as aerospace equipment, or components of electronic equipment.
In the field of chemical research, it is the key to exploring new reactions and new mechanisms. With this, chemists can expand the territory of chemical cognition, discover what has not been discovered before, and promote the progress of chemistry.
From this perspective, O - Trifluoromethyliodobenzene has extraordinary value in many application fields such as medicine, materials, and chemical research, and it is something that cannot be underestimated.
Research & Development
I am committed to the study of O-Trifluoromethyliodobenzene. This material has unique properties and has great potential in various fields of chemical industry. At the beginning, I explored the method of its synthesis. After many attempts, after repeatedly preparing raw materials and adjusting reaction conditions, a feasible path was finally found. Then I studied its properties and gained insight into its performance in different environments.
During the research process, I encountered many problems. If the reaction efficiency is not as expected, the purity of the product is also insufficient. However, I and my colleagues worked tirelessly to study, consult ancient and modern classics, learn from the wisdom of predecessors, and combine modern methods to find ways to improve.
Today, O-Trifluoromethyliodobenzene has gradually developed its strengths and emerged in the fields of material synthesis and drug research and development. In the future, we will continue to focus on this, with the hope of expanding its application, promoting the development of this field, and adding new colors and creating more possibilities for the industry.
Toxicity Research
In the recent O-Trifluoromethyliodobenzene products, its toxicity research is of paramount importance. We need to investigate this substance in detail, and explore its impact on people, all kinds of people and surroundings in various environments.
Test its toxicity, when tested in different creatures, observe the symptoms after their ingestion and exposure. Or there is an acute poison, which is imminent to touch, causing the subject to show abnormalities quickly; or there is a chronic harm, which is only apparent after accumulation, resulting in damage to vitality.
It is also necessary to observe its dispersion, decomposition, and combination with other substances between water and soil. If it escapes in the atmosphere, it can be sown with the wind; if it enters the river and sea, it can be a sewage source and harm the aquarium.
When we study this toxicity, we must use rigorous methods to seek conclusive evidence. It is necessary to clarify its harm, which is the foundation of protection and governance, to ensure the safety of all beings and the cleanliness of the environment.
Future Prospects
I have tried to study O-Trifluoromethyliodobenzene this thing, and I feel that its development in the future is quite impressive. Its unique nature has potential uses in various fields.
Looking at today's world, science and technology are changing day by day, this compound may be able to be used in the development of medicine, shine. With its characteristics, it may help doctors make special drugs and solve people's suffering. In the field of materials science, it is also expected to become a source of innovation, shaping new materials, and meeting future diverse needs.
Although it is not widely used at present, I firmly believe that with time, with the deepening of research and the advancement of technology, it will be able to develop its extraordinary power. The road to the future may be as bright as the stars, opening up a new realm for our generation, leading the ship of science and technology to the unknown and wonderful realm.
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Frequently Asked Questions

As a leading O-Trifluoromethyliodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of O-Trifluoromethyliodobenzene?
O-trifluoromethyl iodobenzene is an important raw material for organic synthesis. It has a wide range of uses and is often a key intermediate for the creation of new drugs in the field of medicinal chemistry. In the development of cover drugs, the precise design of molecular structures is crucial. The trifluoromethyl and iodine atoms of O-trifluoromethyl iodobenzene have unique chemical properties. Trifluoromethyl can change the lipophilic and metabolic stability of compounds, etc. Iodine atoms are prone to various nucleophilic substitution and coupling reactions, which help to construct complex drug molecular structures and improve drug activity and efficacy.
In the field of materials science, it also has extraordinary performance. It can be used to prepare organic materials with special functions, such as optoelectronic materials. By participating in specific chemical reactions, trifluoromethyl can be introduced to adjust the electron cloud distribution and intermolecular forces of the material, thereby optimizing the optical and electrical properties of the material, such as improving the luminous efficiency and improving the charge transport capacity, etc., for the development of advanced materials such as organic Light Emitting Diode (OLED) and organic solar cells.
In pesticide chemistry, it is also indispensable. With its unique structure, synthetic pesticides often have the advantages of high efficiency, low toxicity and high selectivity. The presence of trifluoromethyl can enhance the interaction between pesticide molecules and specific receptors in the target organism, and iodine atoms are conducive to the moderate degradation of pesticide molecules in the environment, reducing residues, and meeting the development needs of modern green pesticides. Overall, O-trifluoromethyliodobenzene plays a key role in many chemical-related fields, promoting technological innovation and progress in various fields.
What are the physical properties of O-Trifluoromethyliodobenzene?
O-trifluoromethyl iodobenzene is also an organic compound. Its physical properties are particularly important, and it is quite useful in the field of chemical industry and scientific research.
Looking at its properties, under normal circumstances, O-trifluoromethyl iodobenzene is a colorless to light yellow liquid with a clear texture and no impurities visible to the naked eye. It has a special smell, although it is not stinky and pungent, it is also different from ordinary odorless substances, and its unique smell can be sensed when smelled.
When it comes to boiling point, it is about 184-186 ° C. At this temperature, the substance gradually changes from liquid to gaseous state, and this characteristic can be exploited in the process of separation and purification. By controlling the temperature, O-trifluoromethyliodobenzene is separated from other substances according to the boiling point to achieve a pure state.
The melting point is about -28 ° C. When the temperature drops below the melting point, the substance will solidify from a liquid state to a solid state. This phase transition is important for storage and transportation under specific conditions.
In terms of density, it is about 1.88 g/cm ³. This value indicates that its density is greater than that of common water, so in the aqueous solution, O-trifluoromethyliodobenzene will settle at the bottom.
Solubility is also an important physical property. It is insoluble in water, but it can be miscible with many organic solvents, such as ether, dichloromethane, toluene, etc. This solubility property facilitates the choice of reaction medium in the process of organic synthesis. Chemists can choose suitable organic solvents according to the needs of the reaction, so that O-trifluoromethyl iodobenzene is evenly dispersed in it, so as to promote the smooth progress of the reaction.
And because it contains trifluoromethyl and iodine atoms, the intermolecular forces have unique characteristics, which in turn affect its physical properties, so that it exhibits different behaviors and characteristics in the research and application of organic chemistry.
What are O-Trifluoromethyliodobenzene synthesis methods?
There are several common methods for preparing o-trifluoromethyl iodobenzene. First, it starts with o-trifluoromethylaniline, and can be formed by the reaction of diazotization and iodine substitution. First, the o-trifluoromethylaniline and sodium nitrite are diazotized in an acidic medium at low temperature to form a diazonium salt. Then, the diazonium salt reacts with an iodine source such as potassium iodide or sodium iodide, and the diazonium group is replaced by an iodine atom to obtain o-trifluoromethyliodobenzene. This step is clear, and the diazotization reaction needs to be carefully controlled at low temperature to prevent the decomposition of diazonium salts.
Second, it can be started from o-trifluoromethylhalobenzene. If it is o-trifluoromethylchlor In the presence of suitable ligands and bases, suitable metal catalysts, such as palladium and copper complexes, are reacted with iodizing reagents, and chlorine or bromine atoms are replaced by iodine atoms to obtain the target product. Among them, the choice of metal catalysts and ligands is very important, which is related to the reactivity and selectivity.
There are also those who use o-trifluoromethylphenylboronic acid as a raw material to react with iodizing reagents under the action of oxidizing agents. o-trifluoromethylphenylboronic acid reacts with an iodine source, such as N-iodosuccinimide (NIS), in the presence of suitable oxidizing agents, to generate o-trifluoromethylbenzene. In this process, the amount of oxidant and reaction conditions need to be regulated in detail to achieve a good yield. Various preparation methods have their own advantages and disadvantages, and the implementation should be based on factors such as raw material availability, cost, and difficulty of reaction conditions.
What O-Trifluoromethyliodobenzene need to pay attention to when storing and transporting
O-trifluoromethyl iodobenzene, as well as organic compounds, should be paid attention to when storing and transporting.
First word storage. This substance has a certain chemical activity and should be stored in a cool, dry and well-ventilated place. Due to heat or moisture, or to cause it to undergo chemical reactions, its quality is damaged. For example, under high temperature, its structure may change, and iodine atoms may fall off more easily, causing the compound to deteriorate. And it should be kept away from fires, heat sources, and open flames to prevent the risk of fire, which may be flammable or combustible. In addition, it needs to be stored separately from oxidants, reducing agents, and bases, because O-trifluoromethyl iodobenzene may react violently with them. In case of strong oxidizing agent, or fluoromethyl is partially oxidized, the product is complicated and unusable.
Times and transportation. During transportation, the packaging must be tight. Use suitable packaging materials to ensure that it is not damaged and leaked on the bumpy road. And the transportation vehicle should be equipped with the corresponding variety and quantity of fire equipment and leakage emergency treatment equipment. If there is a leak during transportation, it can be dealt with in time. During transportation, it is also necessary to prevent sun exposure, rain and high temperature. During summer transportation, it is advisable to choose a cool time in the morning and evening to avoid direct sunlight. For transportation personnel, they should undergo special training and be familiar with the characteristics and emergency treatment methods of O-trifluoromethyl iodobenzene. When loading and unloading, it should also be handled lightly to avoid package damage caused by rough operation. In this way, the safety of storage and transportation can be guaranteed, so that O-trifluoromethyl iodobenzene can be delivered to the required place in good condition.
What are the security risks associated with O-Trifluoromethyliodobenzene?
O-trifluoromethyl iodobenzene is also a commonly used raw material in organic synthesis. It is related to safety risks and needs to be carefully inspected.
This substance has the risk of explosion. In case of open flame and hot topic, it is very easy to burn. If it is mixed with oxidants, the reaction is particularly strong, and there is a risk of explosion. Therefore, when storing and using, it must be kept away from fire sources, heat sources and strong oxidants, and it should be placed in a well-ventilated place to prevent the accumulation of combustible gases.
Toxicity should not be underestimated. Contact with this product may have irritating effects on the eyes, skin, and respiratory mucosa. If inhaled carelessly, it can cause cough, shortness of breath, breathing difficulties and other diseases; percutaneous absorption or ingestion may damage the internal organs. When operating, it must be strictly equipped with protective equipment, such as goggles, gas masks, protective gloves, etc., to avoid contact with it.
Furthermore, it may be harmful to the environment. In soil, water, or difficult to degrade, and or enriched by the food chain, endangering the ecological balance. Therefore, the waste generated during production and use must not be discarded at will, and must be properly disposed of in accordance with relevant environmental regulations.
In short, in the operation and management of O-trifluoromethyl iodobenzene, it is necessary to be cautious and strictly abide by safety procedures to avoid accidents and protect people's safety and the environment.