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O-Chlorofluorobenzene

O-Chlorofluorobenzene

Hongda Chemical

Specifications

HS Code

342363

Chemical Formula C6H4ClF
Molar Mass 130.546 g/mol
Appearance Colorless to light - yellow liquid
Odor Characteristic aromatic odor
Density 1.268 g/cm³ at 20 °C
Boiling Point 129 - 131 °C
Melting Point -37 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in many organic solvents like ethanol, ether
Flash Point 30 °C
Vapor Pressure 3.73 kPa at 25 °C
Refractive Index 1.5025 (20 °C)

As an accredited O-Chlorofluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing O - chlorofluorobenzene: Packed in 25 - kg drums for safe storage and transport.
Storage O - chlorofluorobenzene should be stored in a cool, well - ventilated warehouse. Keep it away from ignition sources and heat. Store it separately from oxidizing agents and reactive chemicals. Ensure containers are tightly sealed to prevent leakage. Use appropriate storage materials resistant to its corrosive nature, following all safety regulations for hazardous chemicals.
Shipping O - chlorofluorobenzene is shipped in tightly - sealed, corrosion - resistant containers. It must comply with hazardous chemical shipping regulations, with proper labeling indicating its properties to ensure safe transportation.
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O-Chlorofluorobenzene O-Chlorofluorobenzene
General Information
Historical Development
In the past, there were chemists who studied a thing called O-Chlorofluorobenzene. The beginning of this thing first appeared in the process of studying chemistry by various sages. At that time, the public devoted themselves to exploring the properties and structure of matter.
O-Chlorofluorobenzene first came out, and everyone was amazed. Because of its unique quality, it is useful in all things in the chemical industry. With the passage of time, those who study it have become more and more popular, and they know that it can be used in the pharmaceutical, material and other industries.
People in the past have repeatedly tested in the laboratory to analyze its composition and measure its characteristics to see if it can be used. Subsequent scholars have continued the work of their predecessors, further refined their research, and expanded their applications, making O-Chlorofluorobenzene an indispensable material in the field of industry. Its historical development depends on the efforts and wisdom of researchers of all dynasties.
Product Overview
"Overview of O-Chlorofluorobenzene Products"
There is a product today called O-Chlorofluorobenzene. Its shape is colorless and its smell is unique. It is a key raw material for organic synthesis and has a wide range of uses in medicine, pesticides, dyes and other fields.
The preparation of this product requires multiple complicated processes, and the reaction conditions are strictly controlled. Temperature, pressure, and catalyst dosage are all related to product quality and yield.
In terms of its characteristics, it has good chemical stability, and there is a risk of explosion in case of open flame and hot topic. When storing, it should be placed in a cool and ventilated place, away from fire and heat sources. The advent of O-Chlorofluorobenzene has injected vitality into the development of many industries, but its production and use should also be handled with caution to ensure safety in order to maximize its effectiveness.
Physical & Chemical Properties
O-Chlorofluorobenzene is an organic compound. Its physical properties, at room temperature, are colorless liquids with a special odor. Its boiling point is about a certain value, which is related to the difficulty of its gasification. Its density is also a specific value, which is related to the ratio of its mass to volume.
On its chemical properties, the substitution of chlorine and fluorine on the benzene ring gives it a unique reactivity. It can react with many reagents, or nucleophilic substitution, or electrophilic addition. Under appropriate conditions, it can react with bases, and chlorine or fluorine atoms can be replaced by other groups. It can also react with some metal catalysts to initiate specific chemical changes to form a variety of products. Due to its special molecular structure, the distribution of electron clouds varies, thus exhibiting such physical and chemical properties.
Technical Specifications & Labeling
Nowadays, there are products for making O-Chlorofluorobenzene, and their technical specifications and labels (commodity parameters) are of paramount importance. To make this product, it is necessary to follow a precise method. First take an appropriate amount of various raw materials and put them into a special device in a certain order. During this time, the temperature control is very strict, and it must be maintained within a certain range to make the reaction smooth.
After it is made, its logo should not be ignored. Detailed product parameters, such as purity geometry and impurity content, must be clear. In this way, this product can be used in accordance with the regulations used and recognized in the market. The technical specifications and labels for making this product are related to quality and are also practical, so they must be strictly followed.
Preparation Method
To prepare O-Chlorofluorobenzene, it is necessary to clarify its raw materials and production process, reaction steps and catalytic mechanism.
Its raw materials are often fluorobenzene and chlorine. In the reactor, specific catalysts, such as iron-based catalysts, are used to make fluorobenzene and chlorine substitution reaction. First heat up to a suitable temperature, about a hundred degrees, so that the reaction system reaches an active state. On the benzene ring of fluorobenzene, the hydrogen atom is replaced by the chlorine atom, and O-Chlorofluorobenzene is produced.
The first step is to mix the raw materials evenly and introduce them into the reactor. The temperature and pressure are controlled to ensure the steady progress of the reaction. And it takes time to observe the reaction process to make timely adjustments. In the
catalytic mechanism, the activation energy of the catalyst to promote the reaction decreases, making it easier to react with fluorobenzene and chlorine. In this process, the activity check point of the catalyst interacts with the reactants to change the reaction path and accelerate the generation of O-Chlorofluorobenzene. In this way, the preparation method of O-Chlorofluorobenzene can be obtained.
Chemical Reactions & Modifications
I am dedicated to the chemical research of O-Chlorofluorobenzene, and I am well aware of the key to its chemical reaction and modification. The reaction of this substance depends on many factors, such as temperature and catalyst, which can affect the result.
In past experiments, it was observed that at a specific temperature, when encountering a certain type of catalyst, the reaction rate was significantly increased, and the purity of the product was also increased. However, the reaction conditions are slightly different, the results are very different.
In order to achieve better modification effect, we are constantly exploring new methods and paths. Try to mix reactants in different proportions to observe the changes in the reaction. Also explore new catalysts, hoping to make the reaction more efficient and accurate.
After repeated study, we finally found a modified reaction process, which can make O-Chlorofluorobenzene under mild conditions to achieve efficient conversion, and the performance of the product can be optimized. This achievement may provide useful reference for the development of related fields.
Synonyms & Product Names
O-Chlorofluorobenzene, organic compounds are also. Its synonymous name is also known as o-chlorofluorobenzene. This substance is quite useful in the chemical industry and can be used as a key intermediate for fine chemicals such as medicine and pesticides.
Although this substance was not detailed in ancient books, today's chemical research has gradually revealed its properties. Its properties are colorless and transparent liquids with a special odor. During the reaction, its chlorine and fluorine properties make the reaction pathways diverse. Because it contains chlorine and fluorine atoms, it has certain stability and reactivity.
The way of industrial preparation often follows a specific chemical process. Many chemical experts study its method and strive to improve the yield and purity. In the market, the name of o-chlorofluorobenzene is also known to everyone. It is required by many industries due to its unique properties. Its synonymous names refer to the same substance, which is of great significance in chemical research and industrial applications.
Safety & Operational Standards
"O-Chlorofluorobenzene Product Safety and Operation Specifications"
O-Chlorofluorobenzene is also a chemical product. In the process of its production and use, safety and operation standards are of paramount importance.
The first word is safety. This substance is dangerous to a certain extent and is related to human health and environmental safety. Therefore, when storing, choose a cool and ventilated storage, away from fire and heat sources. The storage temperature should not exceed 30 ° C. It should be stored separately from oxidants and edible chemicals, and should not be mixed. When handling, be sure to pack and unload lightly to prevent damage to packaging and containers. If there is a leak, evacuate the personnel from the contaminated area to a safe area as soon as possible, quarantine and strictly restrict access. Emergency responders must wear self-contained positive pressure breathing apparatus and gas-proof clothing. Do not let leaks come into contact with combustible substances, and cut off the source of leakage as much as possible. Small leaks can be absorbed by sand, vermiculite or other inert materials. If there are large leaks, embankments or pits should be built for containment, covered with foam to reduce vapor disasters, and transferred to a tanker or a special collector by pump for recycling or transportation to a waste disposal site for disposal.
Secondary operating specifications. Operators must be specially trained and strictly abide by the operating procedures. It is recommended that operators wear self-priming filter gas masks (half masks), chemical safety protective glasses, anti-poison penetration overalls, and rubber oil-resistant gloves. Keep away from fire and heat sources, and smoking is strictly prohibited in the workplace. Use explosion-proof ventilation systems and equipment. Prevent steam from leaking into the air in the workplace. Avoid contact with oxidants. When filling, the flow rate should be controlled, and there should be a grounding device to prevent static electricity from accumulating. When handling, it should be handled lightly to prevent damage to the packaging and containers. Equip with the corresponding variety and quantity of fire equipment and leakage emergency treatment equipment. Empty containers may have harmful residues and need to be properly disposed of.
Only by strictly observing safety and operating standards can we ensure the safety of personnel and protect the environment, so that the application of O-Chlorofluorobenzene can achieve its good results.
Application Area
O - Chlorofluorobenzene is widely used. In the field of medicine, it can be used as a raw material for various medicines. With its special chemical properties, it can help the molecular structure of the medicine, and increase the specialization and strength of the drug effect.
In the field of agriculture and planting, it also has its use. It can be used to make pesticides, to prevent various pests, and to maintain the prosperity of crops. It can prevent the reproduction of pests, protect the health of crops, and lead to the abundance of agricultural products.
And in the genus of material science, it can be used in the process of synthesizing special materials. Make the material specific, such as better corrosion resistance and heat resistance. Provide excellent materials for the industry, construction and other industries, and help their industries to thrive. From this point of view, O-Chlorofluorobenzene has its merits in all fields of use, contributing a lot to the karma of this world.
Research & Development
I am committed to the research of O-Chlorofluorobenzene. This substance also has unique properties and has great potential in the chemical industry.
Initially involved in its research, explored its structure and characteristics, and analyzed its reaction mechanism through repeated experiments. Observe its reaction with various reagents, and record the phenomena and data in detail.
During the research process, many problems were encountered. For example, the precise control of reaction conditions and the improvement of product purity. However, I made unremitting research, consulted ancient books, and learned from the methods of predecessors, and finally achieved results.
As for development, this substance has broad application prospects. It can be used to synthesize new materials and improve product performance. And it may have wonderful uses in the field of medicine, which is expected to help the research and development of new drugs. I will continue to advance my research with the hope of expanding its application, promoting the development of this substance in various fields, and contributing my modest efforts to the progress of the chemical industry.
Toxicity Research
关于邻氯氟苯毒性研究之述
今研邻氯氟苯之毒性,此为化学探究之重。邻氯氟苯者,化学物质也,于工业多有应用。

首观其对生物之影响。以诸生物为试,察其受邻氯氟苯作用之态。入体后,或损脏器,扰生理之序。如啮齿之属,触之则脏器现异,肝功、肾功皆有变动,或因代谢受乱,毒积体内。

再探其环境毒性。散于环境,经水、土、气传。水生态中,扰水生生物之生,或致种群变。土壤里,抑植被之长,改土质之性。大气间,参化反,或生新毒质。

然今之研尚浅,未明其全。后续当拓深度、广度,究长时影响,析毒理之细,期明邻氯氟苯毒性全貌,为防护、用之规立基,避其害而扬其利,保生态与人安。
Future Prospects
In the future world, science and technology are changing with each passing day, and chemical materials will also have great opportunities. Today, there is O-Chlorofluorobenzene, which is an important product for chemical research.
I have studied this material and know its performance and general nature. However, it has not been developed yet, and there is a possibility of improvement. Or in the field of materials, it can be specially made to assist in the research and development of more special materials, used in aerospace to make equipment more efficient; or in the field of materials, by virtue of its chemical properties, it can be new and new, so as to heal all kinds of diseases.
Furthermore, the method of synthesis is also expected to be innovative. It is not possible to obtain it more easily and safely, with less energy consumption and less pollution. In this way, it is not beneficial for work and production, but also for the well-being of the earth. In this way, O-Chlorofluorobenzene will be developed in the future, filled with hope, and will definitely be able to make great progress and great strength.
Where to Buy O-Chlorofluorobenzene in China?
As a trusted O-Chlorofluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading O-Chlorofluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of O-Chlorofluorobenzene?
O-Chlorofluorobenzene (O-Chlorofluorobenzene) is also an organic compound. It has a wide range of uses and is used in all fields of chemical industry.
First, it is often an important intermediate in the synthesis of medicine. Due to its unique chemical structure, Gai can participate in various reactions and help build complex drug molecular structures. Through specific reaction steps, it can combine with other compounds to obtain pharmaceutical ingredients with specific pharmacological activities, making great contributions to pharmaceutical research and development.
Second, it also plays a key role in the field of pesticides. It can be used as a starting material for the synthesis of new pesticides. Based on it, chemically modified and converted, pesticide varieties with high efficiency, low toxicity and good environmental compatibility can be prepared, which can be used for the control of crop diseases and insect pests to ensure the high yield of agriculture.
Third, in the field of materials science, O-chlorofluorobenzene also has its place. Or it can be used to synthesize special polymer materials, endowing materials with excellent properties such as chemical corrosion resistance and high temperature resistance, expanding the application scenarios of materials, and playing important functions in high-end fields such as aerospace and electronics. Fourth, as an important building block of organic synthesis, chemists have derived many organic compounds with different structures through various reactions, such as nucleophilic substitution, electrophilic substitution, etc., starting from O-chlorofluorobenzene, enriching the variety of organic compounds and promoting the development of organic synthesis chemistry.
What are the physical properties of O-Chlorofluorobenzene?
O-chlorofluorobenzene is also an organic compound. Its physical properties are unique and related to chemical, pharmaceutical and other fields.
First of all, its appearance, under normal circumstances, O-chlorofluorobenzene is a colorless and transparent liquid, and it looks clear, like glass, without special turbidity or impurities. This pure state is crucial in many reactions and applications, and its purity affects the quality and characteristics of subsequent products.
Second, its smell is aromatic, but this fragrance is not pleasant and fragrant, but slightly irritating. Smell it, its taste is pungent, easy to cause discomfort to the human senses. Although this pungent odor can be used as a warning sign in some situations, it needs to be protected during operation to avoid endangering human health.
Furthermore, the boiling point is 126-128 ° C. When heated to this temperature range, O-chlorofluorobenzene will gradually change from liquid to gaseous state. This phase transition characteristic is widely used in chemical operations such as distillation and separation. By controlling the temperature, it can be precisely separated from the mixture to obtain high-purity products.
The melting point is about -48 ° C. In a low temperature environment, O-chlorofluorobenzene will condense into a solid state, just as water turns into ice when cooled. This melting point characteristic needs to be carefully considered during storage and transportation. If the ambient temperature is too low or causes it to solidify, it will affect the use and use.
Its density is about 1.263g/cm ³, which is heavier than water. If accidentally mixed with water, it will sink to the bottom of the water. This density difference is different from that of oil-water separation and other related operations.
In terms of solubility, O-chlorofluorobenzene is slightly soluble in water, but easily soluble in most organic solvents, such as ethanol, ether, etc. This solubility makes it often used as a solvent or reactant in organic synthesis reactions to help the smooth progress of the reaction. Due to its good miscibility with organic solvents, the reactants can be fully contacted to improve the reaction rate and efficiency.
What is the chemistry of O-Chlorofluorobenzene?
O-chlorofluorobenzene is also an organic compound. It has the commonality of halogenated aromatics. Chemical properties are active, and the activities vary due to the presence of chlorine and fluorodihalogen atoms.
Chlorine atoms have certain nucleophilic substitution activities, and can be replaced by nucleophilic groups under appropriate nucleophilic reagents and conditions. This reaction is facilitated by a Dorian base or a metal catalyst. If co-heated with sodium alcohol, chlorine can be replaced by alkoxy groups to form corresponding ether compounds.
Although fluorine atoms have high electronegativity and high C-F bond energy, the substitution reaction is difficult, but they can also be replaced under specific strong nucleophilic reagents and harsh conditions. The ortho-site effect is also obvious. Because fluorine and chlorine are in the ortho-site, the electronic effect affects each other, so that the electron cloud density distribution of the benzene ring changes, and the activity of the benzene ring is different from that of benzene and single halogenated benzene.
In the electrophilic substitution reaction, the halogen atom is a blunt group, so the electrophilic substitution activity of the benzene ring decreases. Because the halogen atom has electron-absorbing induction effect and electron-giving conjugation effect, the induction effect is stronger than that of conjugation, the overall electron cloud density of the benzene ring decreases. However, due to the existence of ortho-dihalogen atoms, the steric resistance affects the attack position of the electrophilic reagent, and the proportion of ortho-substitution products may
O-chlorofluorobenzene can form Grignard reagents when it encounters metals such as magnesium. This Grignard reagent has a wide range of uses and can react with carbonyl compounds to form carbon-carbon bonds and form complex organic compounds. And its chemical properties make O-chlorofluorobenzene an important intermediate in the fields of medicine, pesticides, material synthesis, etc. After various reactions, a variety of organic molecules with specific functions can be prepared.
What is O-Chlorofluorobenzene production method?
In the past, there were many ways to prepare o-chlorofluorobenzene. One is to start with o-chloroaniline, which is formed into diazonium salt with fluoroboronic acid, and then decomposed by heating to obtain o-chlorofluorobenzene. This reaction requires careful temperature control, and the raw materials used may have certain toxicity and danger.
Another method uses o-chlorophenol as raw material, first to make phenol salt, and then co-heat with fluorinated reagents, such as potassium fluoride, to obtain o-chlorofluorobenzene through nucleophilic substitution reaction. This process requires high reaction conditions, and appropriate solvents and catalysts are required to promote the smooth reaction.
There are also benzene as the starting material, which is first chlorinated to obtain chlorobenzene, and then fluorinated. However, the selectivity of this approach is not good, and the products are mostly mixtures. To obtain high-purity o-chlorofluorobenzene, complicated separation and purification steps are required.
In recent times, with the advancement of science and technology, there may be better catalytic synthesis methods. With high-efficiency catalysts, the selectivity and yield of the reaction can be improved under milder conditions, but such new methods are still in the research and development stage and have not been widely used in industrial production.
O-Chlorofluorobenzene what are the precautions during use
O-chlorofluorobenzene is also an organic compound. During its use, all kinds of precautions should not be ignored.
First, it is related to safety protection. This substance has certain toxicity and irritation, and you must take strict care of yourself when you come into contact. When handling, wear suitable protective clothing, protective gloves and goggles to prevent it from touching the skin and eyes. If you accidentally get on your body, rinse with plenty of water as soon as possible, and seek medical treatment in severe cases. Work in a well-ventilated place to avoid the accumulation of volatile gas, which can cause harm to inhalation. If inhaled, quickly move to a fresh air place, and if necessary, perform artificial respiration and seek medical attention.
Second, discuss storage conditions. It should be stored in a cool, dry and well-ventilated place, away from fire and heat sources. Do not mix with oxidants, strong alkalis and other substances to prevent chemical reactions from causing danger. The storage area should be equipped with emergency treatment equipment and suitable containment materials.
Third, about the use of specifications. Read the relevant information carefully before use, and be familiar with its nature and hazards. Act according to the correct operating procedures, and do not use in excess. During experiments or production, accurately measure and properly control the reaction conditions, such as temperature, pressure, etc., to prevent accidents. Properly dispose of the residue after use. According to the prescribed procedures, do not dump it at will, and avoid polluting the environment.
Fourth, pay attention to the transportation link. When transporting dangerous chemicals, choose the appropriate transportation tools and packaging methods. Make sure the packaging is in good condition and prevent leakage. During transportation, avoid sun exposure, rain and high temperature, and special personnel will escort it to ensure transportation safety.