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N-Hydroxy-2-(Trifluoromethyl)Benzene Carboximidoyl Chloride

N-Hydroxy-2-(Trifluoromethyl)Benzene Carboximidoyl Chloride

Hongda Chemical

    Specifications

    HS Code

    453614

    Name N-Hydroxy-2-(Trifluoromethyl)Benzene Carboximidoyl Chloride
    Chemical Formula C8H5ClF3NO
    Molar Mass 225.58 g/mol
    Appearance Typically a solid
    Physical State At Room Temperature Solid
    Solubility Soluble in some organic solvents
    Melting Point Data may vary, typically in a certain temperature range for solid compounds
    Density Data may be available in specific references
    Purity Can be specified as a percentage (e.g., 95%, 98% etc. depending on quality)
    Reactivity Reactive towards nucleophiles

    As an accredited N-Hydroxy-2-(Trifluoromethyl)Benzene Carboximidoyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of N - hydroxy - 2 - (trifluoromethyl)benzene Carboximidoyl Chloride in sealed chemical - grade packaging.
    Storage **Storage of N - hydroxy - 2 - (trifluoromethyl)benzene Carboximidoyl Chloride** Store this chemical in a cool, dry, well - ventilated area, away from heat sources and open flames. It should be kept in a tightly sealed container to prevent moisture ingress, as it may react with water. Due to its potentially reactive nature, store it separately from incompatible substances like bases and reducing agents.
    Shipping Shipment of N - hydroxy - 2 - (trifluoromethyl)benzene Carboximidoyl Chloride must follow strict chemical transport regulations. Use appropriate, sealed containers. Ensure proper labeling and documentation for safe and compliant shipping.
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    N-Hydroxy-2-(Trifluoromethyl)Benzene Carboximidoyl Chloride N-Hydroxy-2-(Trifluoromethyl)Benzene Carboximidoyl Chloride
    General Information
    Historical Development
    N-Hydroxy-2- (Trifluoromethyl) Benzene Carboximidoyl Chloride is an important compound in the field of organic chemistry. Tracing its historical development, early chemical research was limited to basic organic synthesis. At that time, the exploration of fluorine-containing compounds was still shallow, and it was difficult to prepare such compounds with special groups.
    However, with the refinement of chemical theory and the innovation of experimental technology, scientists have gradually deepened their understanding of fluorine-containing structures and reactivity. Many new synthesis strategies have emerged to assist in the synthesis of N-Hydroxy-2- (Trifluoromethyl) Benzene Carboximidoyl Chloride. The potential of this compound in the fields of medicine and materials science has begun to emerge, promoting in-depth research. Its historical development has witnessed continuous breakthroughs and progress in chemistry, and is of great significance in modern chemical research.
    Product Overview
    N-Hydroxy-2- (Trifluoromethyl) Benzene Carboximidoyl Chloride is a special product I have encountered in the process of chemical research. Its unique nature, with halogenated imino group, and containing trifluoromethyl benzene ring and hydroxyl group. This product is in the field of organic synthesis, or can be used as a key intermediate.
    Its shape or solid shape, color or white to yellowish, depending on the preparation method and purity. From the perspective of its molecular structure, the introduction of trifluoromethyl increases its fat solubility and chemical stability; while the coexistence of hydroxyl and imine chlorine gives it active reactivity. It may involve various reactions such as nucleophilic substitution and condensation, which is the cornerstone of building a complex organic structure, and has potential in the creation of novel drugs, functional materials, etc. We need to explore it in depth to find out more applications.
    Physical & Chemical Properties
    Today there is a thing called N - Hydroxy - 2 - (Trifluoromethyl) Benzene Carboximidoyl Chloride. Its physical and chemical properties are quite important. Look at its shape, or for a specific state, or with a unique color. Its properties, in different environments, have different manifestations. When heated, or melted or melted, the degree of temperature has its own fixed number. When encountering solvents, it is soluble or insoluble, and it also has its own laws. And its chemical activity cannot be underestimated, and it can react with other things to form new substances. This is the key to studying the physical and chemical properties of this thing. Scholars should explore it in detail to understand why it is, so as to make the best use of it.
    Technical Specifications & Labeling
    Today there is a product called N-Hydroxy-2- (Trifluoromethyl) Benzene Carboximidoyl Chloride. It is very important to study the process specification and identification (product parameters).
    Looking at this substance, the process specification needs to clarify the method of its preparation. From the selection of raw materials, it is necessary to be pure and free of impurities. The reaction conditions, such as temperature, pressure, time, etc., must be precisely controlled without any errors. The reaction equipment should also be clean and compliant to ensure the purity of the product.
    In terms of identification (product parameters), its physical properties, such as color, odor, morphology; chemical properties, such as stability, reactivity, etc. The purity geometry and impurity content of the product need to be clearly marked. In this way, the user can be clear about the characteristics and quality of the product at a glance, use it with confidence, and study it with evidence. This is the essence of the process specification and identification (product parameters) in this product.
    Preparation Method
    This product of N - Hydroxy - 2 - (Trifluoromethyl) Benzene Carboximidoyl Chloride requires the preparation of various raw materials. Take 2 - (trifluoromethyl) benzoic acid as the base, add thionyl chloride, mix the two, and mix them at moderate temperature to make it correspond. In this time, thionyl chloride acts as an acylating agent, and responds with benzoic acid to produce 2 - (trifluoromethyl) benzoyl chloride.
    Next, dissolve 2 - (trifluoromethyl) benzoyl chloride in a suitable solvent, such as dichloromethane, gradually add hydroxylamine hydrochloride and acid binding agent, such as triethylamine. Control its temperature and time, so that the acid chloride and hydroxylamine hydrochloride react to form N-Hydroxy-2- (Trifluoromethyl) Benzene Carboximidoyl Chloride. After finishing, it is purified by separation, washing, steaming, etc., to obtain this product. The whole process, the selection of raw materials, the control of temperature and the order of making are all important for making this product.
    Chemical Reactions & Modifications
    Recently, the chemical reaction and modification of N - Hydroxy - 2 - (Trifluoromethyl) Benzene Carboximidoyl Chloride are very important. Among the various chemical reactions, the conditions change, and the products are often different. If the temperature is slightly changed, or the reaction rate fluctuates, the quality and quantity of the product will also change accordingly.
    And the way of modification is related to the improvement of the performance of this product. Or start with the structure and fine-tune the atomic connection to achieve better characteristics. However, modification is not easy, and every step needs to be considered carefully. The agent of the reaction and the time of the reaction are all key points.
    In order to achieve the ideal application and modification, it is necessary to conduct many tests, observe the results in detail, and summarize the results in order to improve the environment, so that this product can be developed in various fields and is suitable for use.
    Synonyms & Product Names
    N-Hydroxy-2- (Trifluoromethyl) Benzene Carboximidoyl Chloride, this thing is also, its synonymous name and the name of the commodity, there is really something to be investigated. In the field of Guanfu chemistry, one thing is more than one thing, and it is a common thing. This compound may be referred to as another name in ancient books, because the research angle is different, and the naming rules are different.
    Or those named for their structural characteristics highlight the fluorine atom position in their molecular structure and the genus of carboximidoyl chloride. Or from its reaction characteristics and preparation methods, another name may be derived. As for the name of the product, the merchant may give another name for the convenience of promotion and the appearance of its characteristics.
    As an ancient prescription, the same medicinal material is called differently from north to south, but it all refers to the same thing. Although the synonymous names and trade names of chemical substances are diverse, their essence is N-Hydroxy-2- (Trifluoromethyl) Benzene Carboximidoyl Chloride.
    Safety & Operational Standards
    About N - Hydroxy - 2 - (Trifluoromethyl) Benzene Carboximidoyl Chloride Product Safety and Handling Specifications
    Fu N - Hydroxy - 2 - (Trifluoromethyl) Benzene Carboximidoyl Chloride is an important substance in chemical research. When using and operating, safety regulations are of paramount importance.
    This product is dangerous, and the first protection is required when operating. Experimenters must wear complete protective equipment, such as protective clothing, protective gloves and goggles, to prevent it from contacting the skin and eyes. Because it may be corrosive to the skin, it can also cause serious damage to the eyes.
    Furthermore, the operation should be carried out in a well-ventilated place or with the help of a fume hood. If the volatile gas of this product is inhaled into the human body, it may harm health, cause respiratory discomfort, and even cause more serious diseases.
    For storage, when placed in a cool, dry and ventilated place, away from fire and heat sources. Do not mix with oxidants, alkalis, etc., to prevent dangerous chemical reactions.
    When using this product, be sure to operate it accurately and follow the prescribed procedures. After using the utensils, it is necessary to properly clean them in time to prevent residual substances from causing pollution. If a leak occurs accidentally, emergency measures should be taken immediately. Small leaks can be adsorbed by sand, dry lime, etc.; if a large amount leaks, it is necessary to build a dike or dig a pit to contain it, and then dispose of it according to regulations.
    In conclusion, the safety and operation specifications of N-Hydroxy-2- (Trifluoromethyl) Benzene Carboximidoyl Chloride products should be taken with great care, and no slack should be allowed in order to ensure the safety of the research.
    Application Area
    Today there is a substance called N - Hydroxy - 2 - (Trifluoromethyl) Benzene Carboximidoyl Chloride. The application field of this substance is quite critical. In the field of medicine, it can be used as a raw material for synthesizing special drugs to help overcome difficult diseases and relieve suffering for patients. In the field of material chemistry, it can participate in the creation of new materials, so that the material has special properties, such as better stability or unique optical properties. In the field of fine chemicals, it is also an important intermediate. After ingenious transformation, it can derive many high value-added products and promote the progress of the chemical industry. The application of this substance in various fields is waiting for us to explore in depth, so as to make the best use and benefit the world.
    Research & Development
    In modern times, chemistry has flourished, and the research of substances has advanced day by day. I focus on the research of N-Hydroxy-2 - (Trifluoromethyl) Benzene Carboximidoyl Chloride.
    At the beginning, I explored its properties, observed its reaction, and observed its changes under different conditions. Although I encountered various difficulties, such as the control of reactions and the removal of impurities, I did not give up.
    After months of research, I have achieved many results. I know that under specific reagents, it can produce unique reactions and produce different products. This discovery may be used for the creation of new drugs, or it may be of extraordinary use in the field of materials. In the future, we should continue to make progress and expand the application of this material, hoping to contribute to the development of chemistry and the well-being of mankind, so that this research result can be widely disseminated and benefit more industries.
    Toxicity Research
    Today there is a substance named N-Hydroxy-2- (Trifluoromethyl) Benzene Carboximidoyl Chloride. I am a chemical researcher and have been studying its toxicity for a long time. The toxicity of this substance is related to the safety of living beings and cannot be ignored.
    After many experiments, explore its effect on various organisms. Observe its interaction with cells, observe changes in cell morphology and damage to physiological function. In animal experiments, examine the differences in its feeding, activity and physical signs in detail.
    The appearance of toxicity may cause apoptosis or disturb the order of metabolism. Organisms are harmed by it, if it is mild, it will be uncomfortable, and if it is severe, it will endanger life. The purpose of this toxicity study is to clarify its harm, to provide protection and application guidance, so that this chemical can be used in a suitable place to avoid disasters and protect the safety of all things.
    Future Prospects
    In today's world, science and technology are changing with each passing day, and chemical things are also changing with each passing day. Today there is a compound N-Hydroxy-2 - (Trifluoromethyl) Benzene Carboximidoyl Chloride, and its future prospects are really imaginative.
    This compound may be able to develop extraordinary power in various fields of chemistry. On the way of synthesis, it may open up new paths to help chemists make exquisite molecules, laying the foundation for medicine and materials industries. On top of medicine, it may be the key to new pharmaceuticals, and the world can cure difficult diseases; among materials, it may endow materials with strange properties, which should meet diverse needs.
    Our generation of chemical researchers, with the heart of exploration, should be poor in its mysteries. With time and careful study, N-Hydroxy-2- (Trifluoromethyl) Benzene Carboximidoyl Chloride will surely shine, adding a bright touch to the future scientific scene and making far-reaching benefits for human well-being.
    Where to Buy N-Hydroxy-2-(Trifluoromethyl)Benzene Carboximidoyl Chloride in China?
    As a trusted N-Hydroxy-2-(Trifluoromethyl)Benzene Carboximidoyl Chloride manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading N-Hydroxy-2-(Trifluoromethyl)Benzene Carboximidoyl Chloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of N-Hydroxy-2- (Trifluoromethyl) Benzene Carboximidoyl Chloride?
    N-hydroxy-2- (trifluoromethyl) anilimide chloride, this is an organic compound. To clarify its chemical structure, it can be explained by name.
    "N-hydroxy", showing that the nitrogen atom (N) is connected with a hydroxyl group (-OH). "2- (trifluoromethyl) ", the second position of the epiphenyl ring is connected with a trifluoromethyl group (-CF). Trifluoromethyl has strong electron absorption and has a great influence on the properties of compounds. "Benzoimide chloride" refers to the connection between the benzene ring and the anilimide chloride (-C (= NH) Cl), and the carbon and nitrogen double bond in the anilimide chloride is connected to the chlorine atom. The chlorine atom has high activity and is easy to participate in substitution and other reactions.
    In summary, the chemical structure of N-hydroxy-2- (trifluoromethyl) benzoimide chloride is: the second position on the benzene ring is connected to trifluoromethyl, the benzene ring is connected to the methimide chloride, the nitrogen atom of the methimide chloride is connected to the hydroxyl group, and the carbon of the methimide chloride is connected to the chlorine atom. This structure gives the compound unique chemical activity and properties, and is widely used in the field of organic synthesis.
    What are the main uses of N-Hydroxy-2- (Trifluoromethyl) Benzene Carboximidoyl Chloride?
    N-hydroxy-2- (trifluoromethyl) benzoimide chloride, which is a valuable chemical reagent in the field of organic synthesis, has a wide range of uses, probably as follows:
    First, it plays a significant role in the construction of nitrogen-containing heterocyclic compounds. Many nitrogen-containing heterocyclic structures exist in drug-active molecules and natural products. N-hydroxy-2- (trifluoromethyl) benzoimide chloride can be used as a key intermediate. By reacting with various nucleophiles, such as amines and alcohols, it can efficiently construct nitrogen-containing heterocyclic rings with specific structures. For example, the reaction with o-aminophenol may generate benzoxazole derivatives with potential biological activity. Such reactions open up important paths for the creation of new drugs and the exploration of compounds with unique physiological activities.
    Second, in the formation of amide bonds, amide bonds are widely found in peptides, proteins, and many drug molecular structures. The compound can react with amines and undergo a series of transformations to form amide compounds. This reaction condition is relatively mild and has good selectivity. In the field of peptide synthesis, or when preparing amide compounds with specific structures and functions, it can be used as an effective method to help researchers accurately synthesize the desired target products.
    Third, because it is rich in trifluoromethyl groups in the molecule, it endows the product with unique physical and chemical properties, such as improving lipophilicity and enhancing metabolic stability. Therefore, in the field of pesticide research and development, N-hydroxy-2- (trifluoromethyl) benzoimide chloride can be used to synthesize new pesticides with high efficiency, low toxicity and environmentally friendly properties. By rationally designing the reaction, trifluoromethyl can be introduced into the molecular structure of pesticides to optimize the performance of pesticides and make it more suitable for the needs of modern agriculture for green and efficient pesticides.
    What is the synthesis method of N-Hydroxy-2- (Trifluoromethyl) Benzene Carboximidoyl Chloride?
    The method of preparing N-hydroxy-2- (trifluoromethyl) benzoimide chloride has been explored in the field of organic synthesis. The method is roughly as follows:
    Usually 2 - (trifluoromethyl) benzoic acid is used as the starting material, and it is first heated with thionyl chloride. The two are combined, as the ancients said, "Yin and yang sympathize, and all things are transformed". The carboxyl group of benzoic acid interacts with thionyl chloride, and the carboxyl group is converted into an acyl chloride to obtain 2 - (trifluoromethyl) benzoyl chloride. In this step, attention should be paid to the temperature and duration of the reaction. If the temperature is too high, side reactions will occur, and if it is too low, the reaction will be slow.
    Then, 2 - (trifluoromethyl) benzoyl chloride and hydroxylamine hydrochloride meet in a suitable solvent, such as dichloromethane, accompanied by an acid binding agent such as triethylamine. The responsibility of the acid binding agent is to remove the acid generated by the reaction, so that the reaction can proceed smoothly. The two are changed by nucleophilic substitution, and the acid chloride group is connected to the nitrogen atom in the hydroxylamine, and the final N-hydroxy-2 - (trifluoromethyl) benzoimide chloride is obtained.
    There are also other methods for synthesis, but the above method has many advantages for the convenience of operation and the excellent yield. When synthesizing, the purity of the raw materials and the conditions of the reaction need to be carefully controlled, such as tuning the piano and a trace of abnormal sound, so as to obtain high-purity products.
    What are the physical properties of N-Hydroxy-2- (Trifluoromethyl) Benzene Carboximidoyl Chloride?
    N-hydroxy-2 - (trifluoromethyl) benzoimide chloride, this is an organic compound. Its physical properties are crucial and are related to many chemical processes and applications.
    The first to bear the brunt, looking at its appearance, it is usually white to off-white crystalline powder. This form is easy to store and use, and reflects the order of its molecular arrangement. The texture of the powder is fine, easy to disperse, and can provide a large contact area in the chemical reaction, which is conducive to the efficient progress of the reaction.
    Furthermore, in terms of its melting point, it is in a specific temperature range. Determination of melting point is an important indicator for identification and purity evaluation. A specific melting point range indicates that the compound has a relatively uniform structure and purity. If the melting point deviates from the expected range, or suggests the presence of impurities, it will affect its chemical properties and reactivity.
    When it comes to solubility, it shows good solubility in common organic solvents, such as dichloromethane, chloroform, and tetrahydrofuran. This property makes it convenient to participate in the chemical reactions of various solution phases. In organic synthesis, suitable solvents can be selected according to the reaction requirements to create a good reaction environment and promote the full mixing and interaction of the reactants, thereby improving the reaction efficiency and selectivity.
    Its density is also an important parameter. Density reflects the compactness of the substance and is related to the molecular weight and intermolecular interactions of the compound. The specific density value helps to accurately measure and use the compound in actual operation, ensuring the accuracy and reproducibility of the experiment.
    In addition, stability is also a key consideration. Under normal storage conditions, the compound has certain stability. However, care should be taken to avoid contact with specific substances, such as strong oxidants, strong bases, etc., to prevent adverse reactions that lead to decomposition or deterioration.
    The physical properties of N-hydroxy-2- (trifluoromethyl) benzoimide chloride are of great significance in the fields of organic synthesis and drug development. Researchers need to deeply understand and make good use of these properties in order to promote the development of related fields.
    What are the storage conditions for N-Hydroxy-2- (Trifluoromethyl) Benzene Carboximidoyl Chloride?
    N-hydroxy-2 - (trifluoromethyl) benzoimide chloride is a chemical substance. The storage conditions are crucial, and it is related to the stability and quality of its properties.
    This medicine should be placed in a cool and dry place. Cover a cool environment, which can slow down the speed of its reaction, and prevent its decomposition or change its properties due to heat. If it is in a hot place, the molecular speed is easy to cause internal change, which damages its structure and energy. Drying should not be ignored. Water vapor is often a medium for chemical reaction. When this medicine encounters water, it may respond to hydrolysis and lose its original effect. Therefore, avoiding water and preventing moisture is an important rule for storage.
    And it must be placed in a closed device. If exposed to gas, it will come into contact with oxygen, carbon dioxide, etc., or oxidize. Oxygen can cause it to oxidize and change its chemical structure; carbon dioxide may also be neutralized with it, causing a qualitative change. The secret device can isolate the outside air and protect its pure quality.
    Furthermore, keep away from fire and heat sources. This medicine may be flammable or explosive. In case of fire and heat, it is feared that it will react violently, leading to a dangerous situation. Fire can cause it to explode, and heat sources can also promote its transformation to accelerate, causing unpredictable changes.
    And it should be stored separately from oxidized and reduced substances. Oxidation agents and reducing agents are easy to react with and the like, and can be stored separately to avoid unwanted chemical reactions and ensure their safety and efficacy.
    In short, the storage of N-hydroxy-2- (trifluoromethyl) benzoimide chloride must be cool, dry, airtight, protected from fire and heat sources, and stored separately from others to obtain its full quality for later use.