As a leading N-[(4-Methoxy-6-Methyl-1,3,5-Triazin-2-Yl)Carbamoyl]-2-(3,3,3-Trifluoropropyl)Benzenesulfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical structure of N- [ (4-methoxy-6-methyl-1,3,5-triazine-2-yl) carbamoyl] -2- (3,3,3-trifluoropropyl) benzenesulfonamide
This compound is named N- [ (4-methoxy-6-methyl-1,3,5-triazine-2-yl) aminoformyl] -2 - (3,3,3-trifluoropropyl) benzenesulfonamide, and its chemical structure is analyzed as follows:
Start with the name and start with the main structure. "Benzenesulfonamide" indicates that the core structure is a phenyl ring-linked sulfonamide group (-SO 2O NH-). "2 - (3,3,3-trifluoropropyl) " indicates that a 3,3,3-trifluoropropyl group (CF < CF < CF > CF < 2O -) is connected at position 2 of the benzene ring.
On the other side, "N - [ (4-methoxy-6-methyl-1,3,5-triazine-2-yl) carbamoyl]" section, "carbamoyl" (-CONH -) is attached to the nitrogen atom (N) of benzenesulfonamide, and " (4-methoxy-6-methyl-1,3,5-triazine-2-yl) " is attached to the carbamoyl of carbamoyl. 1,3,5-triazine is a six-membered heterocyclic ring composed of three nitrogen atoms and three carbon atoms alternately, with methoxy (-OCH) at position 4, methyl (-CH) at position 6, and aminoformyl at position 2.
In summary, the chemical structure of this compound is based on benzenesulfonamide, which is connected to 3,3,3-trifluoropropyl at position 2, and sulfonamide nitrogen atom (4-methoxy-6-methyl-1,3,5-triazine-2-yl) carbamoyl.
What are the physical properties of N- [ (4-methoxy-6-methyl-1,3,5-triazine-2-yl) carbamoyl] -2- (3,3,3-trifluoropropyl) benzenesulfonamide
N - [ (4-methoxy-6-methyl-1,3,5-triazine-2-yl) aminoformyl] - 2 - (3,3,3-trifluoropropyl) benzenesulfonamide is an organic compound. Its physical properties are as follows:
- ** Appearance and Properties **: Usually white to off-white crystalline powder, this is the common appearance of many organic sulfonamide compounds, and the powder shape is conducive to its uniform dispersion in chemical reactions and preparations.
- ** Melting point **: In view of the intermolecular force and structural stability of the compound, the melting point is in a specific range, and the exact value needs to be determined experimentally. Melting point is a key indicator for the identification and purification of organic compounds. Its purity and structural integrity can be preliminarily judged by melting point.
- ** Solubility **: It exhibits some solubility in organic solvents such as dichloromethane, N, N-dimethylformamide (DMF), but poor solubility in water. This is related to the relative proportion and distribution of hydrophobic groups (such as methyl, trifluoropropyl) and hydrophilic groups (sulfonamido, carbamoyl) in the molecular structure. Good solubility in organic solvents facilitates its participation in organic synthesis reactions, because many organic reactions are carried out in organic solvent systems.
- ** Density **: Density, as the basic physical properties of substances, is closely related to molecular mass and molecular accumulation. The specific density value needs to be measured experimentally, which is of great significance for its behavior in solution systems and the determination of material proportions during preparation development.
- ** Stability **: Under conventional storage conditions, the compound has certain stability if extreme environments such as light, high temperature, and high humidity are avoided. However, in case of strong oxidants, strong acids, or strong bases, due to the activity of some chemical bonds (such as amide bonds and sulfonamide bonds) in the structure, chemical reactions may occur to cause structural changes.
What are the application fields of N- [ (4-methoxy-6-methyl-1,3,5-triazine-2-yl) carbamoyl] 2- (3,3,3-trifluoropropyl) benzenesulfonamide
N - [ (4-methoxy-6-methyl-1,3,5-triazine-2-yl) aminoformyl] - 2 - (3,3,3-trifluoropropyl) benzenesulfonamide, which has a wide range of uses. In the field of medicine, it may be a key raw material for the creation of new antimalarial drugs. Malaria is rampant and endangers people. This compound may be able to effectively inhibit the development and reproduction of malaria parasites through a specific chemical mechanism, opening up a new path for the development of antimalarial drugs.
In the field of pesticides, it can be used as a core component in the creation of high-efficiency insecticides. Pests often invade farmland, causing crops to fail. The compound may act precisely on the nervous system or physiological metabolic pathway of pests, killing insects efficiently, and is relatively friendly to the environment, helping agricultural harvest and maintaining ecological balance.
In the field of materials science, it may be used to prepare functional materials with special properties. For example, after specific process treatment, or endowing the material with excellent UV resistance and oxidation resistance, the material can be used in outdoor facilities, plastic products, etc., prolonging the service life of the material and reducing the replacement cost.
What is the preparation method of N- [ (4-methoxy-6-methyl-1,3,5-triazine-2-yl) carbamoyl] -2- (3,3,3-trifluoropropyl) benzenesulfonamide
To prepare N- [ (4-methoxy-6-methyl-1,3,5-triazine-2-yl) aminoformyl] -2- (3,3,3-trifluoropropyl) benzenesulfonamide, the method is as follows:
First take an appropriate amount of (4-methoxy-6-methyl-1,3,5-triazine-2-yl) amine, place it in a clean reaction vessel, add an appropriate amount of organic solvent, such as dichloromethane, N, N-dimethylformamide, etc., stir to dissolve it uniformly.
Take another 2- (3,3,3-trifluoropropyl) benzenesulfonyl chloride and slowly add it dropwise to the above solution containing (4-methoxy-6-methyl-1,3,5-triazine-2-yl) amine. The reaction temperature needs to be controlled during the dropwise addition process, which can generally be maintained between 0 ° C and room temperature to prevent the reaction from being too violent. After the dropwise addition is completed, heat up to an appropriate temperature, such as 30 ° C - 50 ° C, and continue to stir the reaction for several hours. During this period, the reaction progress can be monitored by thin layer chromatography (TLC) until the raw material point basically disappears, indicating that the reaction tends to be complete.
After the reaction is completed, pour the reaction solution into an appropriate amount of water, extract it with an organic solvent such as ethyl acetate, and collect the organic phase by separation. The organic phase is then washed several times with saturated saline water, dried with a desiccant such as anhydrous sodium sulfate, and filtered to remove the desiccant. Finally, the organic solvent was removed by reduced pressure distillation, and the resulting residue was further purified by column chromatography. Petroleum ether and ethyl acetate were mixed in an appropriate proportion as eluents to collect the eluent containing the target product, and the solvent was evaporated to obtain pure N - [ (4-methoxy-6-methyl-1,3,5-triazine-2-yl) aminoformyl] -2 - (3,3,3-trifluoropropyl) benzenesulfonamide. The whole operation process should be carried out in a well-ventilated environment, and the reaction conditions and operation details should be strictly controlled to ensure the purity and yield of the product.
What are the safety precautions for N- [ (4-methoxy-6-methyl-1,3,5-triazine-2-yl) carbamoyl] -2- (3,3,3-trifluoropropyl) benzenesulfonamide
N - [ (4-methoxy-6-methyl-1,3,5-triazine-2-yl) aminoformyl] - 2 - (3,3,3-trifluoropropyl) benzenesulfonamide compounds, the safety precautions for such compounds, I would like to tell you in detail.
These compounds are often involved in the field of chemical synthesis, and the first protection is required during operation. Because of their irritation, the operator must wear complete protective equipment, such as chemical-resistant protective clothing, gloves, and goggles and gas masks, to prevent them from coming into contact with the skin, eyes, or entering the body through the respiratory tract.
Furthermore, in terms of storage, it should be placed in a cool, dry and well-ventilated place, away from fire and heat sources. Due to its chemical nature or activity, improper storage environment, such as high temperature, humidity, or deterioration, can even cause dangerous chemical reactions.
The experimental operation room also needs to have perfect ventilation facilities to dissipate harmful gases that may be volatilized. And during the operation, act in strict accordance with the standard process, accurately control the temperature, control the time and the amount of reactants, and must not be arbitrarily changed to prevent the reaction from getting out of control.
In addition, such waste compounds must not be discarded at will, and should be properly disposed of in accordance with relevant environmental regulations to avoid defacement of the environment. Overall, the safe handling, storage, and disposal of such compounds should be handled with caution and without any slack to ensure personal safety and environmental safety.