This compound is named N - [ [ ( 4-methoxy-6-methyl-1,3,5-triazine-2-yl) amino] carbonyl] -2- (3,3,3-trifluoropropyl) benzenesulfonamide. Its chemical structure is analyzed as follows:
First, the core structure is benzenesulfonamide, that is, the benzene ring is connected to the sulfonyl group (-SO 2O -), and the sulfonyl group is then connected to the amino group (-NH 2O) to form a sulfonamide structure. A 3,3,3-trifluoropropyl group is connected at the 2-position of the benzene ring, and the three fluorine atoms of this propyl group are located on the terminal carbon atom.
Next, a complex structure is attached to the nitrogen atom of the sulfonamide. This structure is based on a 1,3,5-triazine ring with a 4-position attached to methoxy (-OCH 🥰), a 6-position attached to methyl (-CH 🥰), and a 2-position attached to an aminoformyl group (-NH - CO -). The nitrogen atom of this aminoformyl group is attached to the nitrogen atom of benzenesulfonamide. In this way, the chemical structure of N - [ [ ( 4 -methoxy-6 -methyl-1,3,5 -triazine-2-yl) amino] carbonyl] -2 - (3,3,3 -trifluoropropyl) benzenesulfonamide is formed. This structure may have unique properties and applications in the field of organic synthesis and medicinal chemistry, and its different substituents endow compounds with diverse physicochemical properties and potential biological activities.

This is a chemical substance named N- [ (4-methoxy-6-methyl-1,3,5-triazine-2-yl) aminoformyl] -2 - (3,3,3-trifluoropropyl) benzenesulfonamide. Its physical properties are quite critical, and it is widely used in chemical, materials, medicine and other fields, which is related to product performance and quality.
Looking at its state, under normal temperature and pressure, it is mostly white to almost white crystalline powder. This form makes it have good fluidity and dispersion, and it is easier to mix evenly when preparing various preparations or composites, thereby ensuring stable and uniform product quality.
When it comes to the melting point, it is about 130-135 ° C. As an important physical property of a substance, the melting point has a profound impact on its production, processing and application. In this temperature range, the substance is melted from a solid state to a liquid state, and the heating temperature and time can be precisely controlled during production to meet the needs of specific processing processes, such as melt extrusion, hot pressing, etc.
The solubility cannot be ignored. It exhibits good solubility in organic solvents such as dichloromethane, N, N-dimethylformamide (DMF), but it is difficult to dissolve in water. This property is of great significance in the field of drug development. After dissolving with organic solvents, it can be made into a variety of dosage forms, such as injections, solutions, etc., in order to better exert its efficacy. At the same time, the insoluble nature of water can enhance the water resistance and stability of the material in some application scenarios that require waterproof and moisture resistance.
In addition, the density of the material is about 1.4 - 1.5 g/cm ³, which allows it to effectively adjust the density and weight of the material when participating in the material formulation to meet the specific requirements of material density in different application scenarios. In fields such as aerospace and automobile manufacturing, there are strict standards for material density.
In summary, these physical properties of N - [ (4-methoxy-6-methyl-1,3,5-triazine-2-yl) aminoformyl] -2 - (3,3,3-trifluoropropyl) benzenesulfonamide play a pivotal role in practical applications in various related fields, laying a solid foundation for its wide application.

This is a rather complex drug named N - [ [( 4-methoxy-6-methyl-1,3,5-triazine-2-yl) amino] phenyl] -2 - (3,3,3-trifluoropropyl) quinazoline-4-amine. It has a wide range of uses in the field of medicinal chemistry, mainly in the development of anti-tumor drugs.
Due to the unique chemical structure of this compound, it is endowed with specific biological activity. Among them, triazinyl and quinazoline structures are common in many anti-tumor drugs, and can specifically bind to some key targets in tumor cells. For example, by interacting with specific kinases related to tumor cell proliferation, it blocks cell signaling pathways, thereby inhibiting the growth and proliferation of tumor cells.
At the same time, substituents such as methoxy, methyl and trifluoropropyl also have important effects on their pharmacological properties. Methoxy and methyl can regulate the lipid solubility and electron cloud distribution of molecules, optimizing the affinity of compounds and targets; the strong electron-absorbing properties of trifluoropropyl can enhance the stability of molecules and cell membrane permeability, making it easier for drugs to enter tumor cells to play their roles. In addition, in the process of drug development, such compounds can also be used as lead compounds to further enhance their anti-tumor activity and reduce toxic and side effects through structural modification and optimization, providing an important foundation and direction for the creation of new anti-tumor drugs.

To prepare N- [ (4-methoxy-6-methyl-1,3,5-triazine-2-yl) amino] -2- (3,3,3-trifluoropropyl) benzenesulfonamide, the synthesis method is as follows:
First take 4-methoxy-6-methyl-1,3,5-triazine-2-amine as the starting material, in a suitable reaction vessel, add an appropriate amount of organic solvents, such as dichloromethane, N, N-dimethylformamide, etc., to facilitate the reaction. After stirring well, slowly add acid binding agents, such as triethylamine, pyridine, etc., to neutralize the acid produced by the reaction and promote the positive movement of the reaction.
Slowly add 2 - (3,3,3 - trifluoropropyl) benzenesulfonyl chloride dropwise to the above mixed system. When adding dropwise, pay attention to the control of the reaction temperature, which can generally be maintained between 0 ° C and room temperature to prevent the reaction from being too violent. After the dropwise addition is completed, heat up to an appropriate temperature, such as 30 ° C - 50 ° C, and continue to stir the reaction for several hours. During this period, the reaction progress can be monitored by means of thin layer chromatography (TLC) until the raw material point basically disappears, indicating that the reaction has reached the expected level.
After the reaction is completed, pour the reaction solution into an appropriate amount of water and extract the product with an organic solvent. The organic phase is collected, washed with saturated saline water in turn, and dried with anhydrous sodium sulfate to remove the water. Subsequently, the organic solvent is removed by distillation under reduced pressure to obtain a crude product.
The crude product is purified by column chromatography. Select a suitable silica gel column and eluent, such as petroleum ether and ethyl acetate mixed in a certain proportion as eluent, and collect the eluent containing the target product. Pure N - [ (4-methoxy-6-methyl-1,3,5-triazine-2-yl) amino] -2 - (3,3,3-trifluoropropyl) benzenesulfonamide can be obtained by distillation under reduced pressure.
During the whole synthesis process, attention should be paid to the precise control of reaction conditions, the purity of raw materials and reagents, and the separation and purification of each step of the reaction to obtain the ideal product yield and purity.

This is related to the safety precautions of N - [ [( 4 - methoxy - 6 - methyl - 1,3,5 - triazine - 2 - yl) amino] phenyl] - 2 - (3,3,3 - trifluoropropyl) quinazoline - 4 - one. This compound has a specific chemical structure, and the following points must be paid attention to when using and handling:
First, protective measures are essential. Due to its unknown chemical properties, appropriate protective clothing, such as lab clothes and gloves, should be worn when exposed to prevent skin contamination; wear goggles to avoid splashing into the eyes and causing damage. If you accidentally come into contact with the skin, you should immediately rinse with a large amount of water and seek medical attention as appropriate; if it catches your eyes, you need to rinse with a large amount of water immediately and seek professional medical assistance as soon as possible.
Second, the operating environment should also be paid attention to. It should be operated in a well-ventilated place, preferably in a fume hood, to prevent the accumulation of gases formed by the volatilization of the substance and inhalation by the human body. Due to its complex chemical structure, volatile gases may cause potential harm to the respiratory tract, nervous system, etc. If you smell an abnormal odor during operation, you should stop immediately, check the ventilation equipment, and evacuate the scene personnel.
Third, storage should also be paid attention to. Store in a cool, dry and well-ventilated place, away from fire and heat sources. Due to its chemical properties or instability, it can be heated, exposed to open flames, or cause serious accidents such as combustion and explosion. At the same time, it should be stored separately from oxidants, acids, alkalis, etc., to avoid chemical reactions and lead to danger.
Fourth, waste disposal should not be underestimated. Waste such as residues and packaging after use must not be discarded at will. It should be collected and properly disposed of in accordance with local regulations and laboratory regulations. Because it may contain toxic and corrosive ingredients, discarding it at will will pollute the environment and endanger the ecology. Special methods may be required by professional institutions to ensure safety and harmlessness.