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N-[4-[[3-Chloro-4-[(3-Fluorophenyl)Methoxy]Phenyl]Amino]-6-Quinazolinyl]-2-Propenamide 4-Methylbenzenesulfonate

N-[4-[[3-Chloro-4-[(3-Fluorophenyl)Methoxy]Phenyl]Amino]-6-Quinazolinyl]-2-Propenamide 4-Methylbenzenesulfonate

Hongda Chemical

Specifications

HS Code

954609

Chemical Name N-[4-[[3-Chloro-4-[(3-Fluorophenyl)Methoxy]Phenyl]Amino]-6-Quinazolinyl]-2-Propenamide 4-Methylbenzenesulfonate

As an accredited N-[4-[[3-Chloro-4-[(3-Fluorophenyl)Methoxy]Phenyl]Amino]-6-Quinazolinyl]-2-Propenamide 4-Methylbenzenesulfonate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of N -[4 -[[3 -chloro -4 -[(3 -fluorophenyl)methoxy]phenyl]amino]-6 -quinazolinyl]-2 -propenamide 4 -methylbenzenesulfonate in sealed vial.
Storage Store the chemical “N -[4 -[[3 - chloro - 4 -[(3 - fluorophenyl)methoxy]phenyl]amino]-6 - quinazolinyl]-2 - propenamide 4 - methylbenzenesulfonate” in a cool, dry place away from direct sunlight. Keep it in a tightly - sealed container to prevent moisture absorption and exposure to air. Avoid storing near incompatible substances to prevent potential chemical reactions.
Shipping Ship the chemical "N-[4-[[3 - chloro - 4 - [(3 - fluorophenyl)methoxy]phenyl]amino]-6 - quinazolinyl]-2 - propenamide 4 - methylbenzenesulfonate" in sealed, corrosion - resistant containers via approved hazardous chemical carriers following all safety regulations.
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N-[4-[[3-Chloro-4-[(3-Fluorophenyl)Methoxy]Phenyl]Amino]-6-Quinazolinyl]-2-Propenamide 4-Methylbenzenesulfonate N-[4-[[3-Chloro-4-[(3-Fluorophenyl)Methoxy]Phenyl]Amino]-6-Quinazolinyl]-2-Propenamide 4-Methylbenzenesulfonate
General Information
Historical Development
The research of medicine is also related to the health of people's livelihood, and it has been important in all generations. Today there are N - [4 - [[3 -Chloro -4 - [ (3 -Fluorophenyl) Methoxy] Phenyl] Amino] -6 -Quinazolinyl] -2 -Propenamide 4 -Methylbenzenesulfonate this medicine. At the outset, the medical workers worked hard to explore the properties and pharmacology. At the beginning, it was only studied in the case, and then it was proved by various experiments. After years, generations of researchers have continued to study the past and the future, and they have been unremitting. Either the identification of physical properties is wrong, or the test of effectiveness is not precise, but they are all determined. From the end of the observation to the understanding of the effect, it is difficult step by step. The success of this medicine today depends on the contributions of all researchers. It has made great contributions to the progress of medicine. Its historical evolution is also a lesson for later generations to study medicine.
Product Overview
There is a substance called N- [4- [[3-chloro-4- [ (3-fluorophenyl) methoxy] phenyl] amino] -6-quinazolinyl] -2-acrylamide 4-methylbenzene sulfonate. This compound has a delicate and complex structure. It contains chlorine, fluorine and other atoms, which are connected by unique chemical bonds. Chlorine in a specific position affects its chemical activity; fluorophenyl methoxy group, or plays a role in its solubility and stability. Quinazolinyl group cooperates with acrylamide and benzene sulfonate partially, or determines the performance of the substance in a specific reaction. This substance may have potential uses in the fields of medicine, chemical industry, etc. However, it is necessary to deeply explore its properties and reaction characteristics in order to understand its practical application value and maximize its effectiveness.
Physical & Chemical Properties
There is a substance called N- [4- [[3-chloro-4- [ (3-fluorophenyl) methoxy] phenyl] amino] -6-quinazolinyl] -2-acrylamide 4-methylbenzene sulfonate. As a chemical researcher, I observe its physical and chemical properties. This substance has unique properties, which are related to its microstructure and intermolecular interactions. Its melting point and boiling point are related to molecular stability and thermal motion characteristics; its solubility is related to the affinity of solvent molecules. The density reflects the relationship between its mass and volume, reflecting the dense arrangement of internal particles. Its chemical activity is driven by functional groups, and under specific conditions, it may react with substitution and addition. Exploring the physical and chemical properties of this substance can pave the way for its application, and it may be able to shine in the fields of medicine and materials.
Technical Specifications & Labeling
Today there is a thing called N- [4- [[3-chloro-4- [ (3-fluorophenyl) methoxy] phenyl] amino] -6-quinazolinyl] -2-acrylamide 4-methylbenzene sulfonate. Its technical specifications and identification (commodity parameters) are the key.
When it comes to technical specifications, it is necessary to refine the ratio of materials, and the ratio of each component must be accurate. For example, 3-chloro-4- [ (3-fluorophenyl) methoxy] phenyl, quinazolinyl and other parts must be synthesized according to a specific number. The temperature and duration of the reaction should not be ignored, and it must be stabilized within a suitable range to ensure the quality of the product.
As for the logo, when the chemical structure of the characterization, in order to facilitate identification. In the product parameters, purity, traits, etc. should be detailed, so that the user can know its characteristics. In this way, the technical specifications and labels of this product can be obtained to become a good product.
Preparation Method
The method of preparing N- [4- [[3-chloro-4- [ (3-fluorophenyl) methoxy] phenyl] amino] -6-quinazolinyl] -2-acrylamide-4-methylbenzene sulfonate is related to the raw materials, production process, reaction steps and catalytic mechanism.
The precursor is based on 3-chloro-4- [ (3-fluorophenyl) methoxy] aniline and 6-haloquinazoline, according to a specific ratio. In a suitable reaction vessel, adjust the temperature to a certain range, and add a catalyst, which is the key to the catalytic mechanism. Catalysis can promote the reaction rate, reduce energy consumption, and increase the yield.
The reaction steps are orderly, and the reaction time and temperature change are controlled. At the beginning, slow heating leads to the start of the reaction, and then stabilize the temperature to allow the reaction to proceed, during which the reaction state is closely observed. After the reaction is completed, the pure product is obtained through separation and purification.
The production process carefully selects heavy raw materials, controls the reaction conditions, and guarantees the yield of substances and yields. This method can be optimized after repeated research and development, and can obtain excellent yield.
Chemical Reactions & Modifications
There is now a thing called N- [4- [[[3-chloro-4- [ (3-fluorophenyl) methoxy] phenyl] amino] -6-quinazolinyl] -2-acrylamide 4-methylbenzene sulfonate. In the field of chemistry, I have devoted myself to studying its chemical reaction and modification. Examine the rules of its reaction, consider the changes in its structure, and hope to change its properties to meet all kinds of needs. In order to seek the stability of the reaction and the excellence of its properties, it is necessary to study its chemical principles in detail, analyze the dissociation of its atoms, and the disconnection of its bonds. Through various explorations, this substance should be used in the pharmaceutical, materials, and other industries to develop its strengths, avoid its weaknesses, and be used by the world. It also contributes to the chemical research industry and promotes its progress.
Synonyms & Product Names
There is a substance called N- [4- [[3-chloro-4- [ (3-fluorophenyl) methoxy] phenyl] amino] -6-quinazolinyl] -2-acrylamide 4-methylbenzene sulfonate. This substance is unique in our field of chemical research.
Its synonyms and trade names are the key to exploration. Although the chemical nomenclature is accurate, the synonyms and trade names used in daily life are more widely circulated in the industry. In practical application and communication, different names often refer to the same thing, just like the different names of ancient times.
If you want to understand the whole picture, you need to check the synonyms and trade names in detail. The names are changeable depending on the manufacturer or the application scene. All of this requires our careful screening, just like the collation of ancient books, removing falsehoods and preserving the truth, so that we can be handy in research, production and application.
Safety & Operational Standards
Today there is a product called N- [4- [[3-chloro-4- [ (3-fluorophenyl) methoxy] phenyl] amino] -6-quinazolinyl] -2-acrylamide 4-methylbenzene sulfonate. This product is related to chemical research, and its safety and operation standards should be treated with caution.
At the safe end, the first protection. When exposed to this product, protective equipment such as gloves, goggles and protective clothing must be adapted to protect against possible hazards. Because it may be irritating, accidental contact with the skin and eyes can cause injury. And this thing smells, or it is also harmful to breathing, so it is necessary to operate in a well-ventilated place, and if necessary, a respirator should be prepared.
Operating specifications should not be ignored. Before the experiment, all utensils must be clean and dry to prevent impurities from disturbing. When measuring this thing, use a precise measuring tool and operate according to regulations without deviation. When mixing, the action should be slow and continue to stir to make uniform fusion. The reaction process needs to be closely monitored. Temperature, time and other parameters are all related to success or failure and safety.
Furthermore, storage should also be paid attention to. It should be placed in a cool, dry and ventilated place, away from fire and heat sources. Classified storage, do not coexist with contraband objects to prevent accidents. When discarded, it should be disposed of in accordance with environmental protection regulations and should not be discarded at will to avoid polluting the environment.
In short, in the research of N- [4- [[3-chloro-4- [ (3-fluorophenyl) methoxy] phenyl] amino] -6 -quinazolinyl] -2 -acrylamide 4 -methylbenzene sulfonate, safety and operation specifications such as two wheels of a car and two wings of a bird are indispensable. Our generation should keep it in mind and practice it.
Application Area
There is a compound called N- [4- [[3-chloro-4- [ (3-fluorophenyl) methoxy] phenyl] amino] -6-quinazolinyl] -2-acrylamide 4-methylbenzene sulfonate. The application field of this compound is quite critical. In the field of medicine, it may participate in the treatment of diseases, with its unique chemical structure, or can act on specific biological targets to help overcome diseases. In the chemical industry, it may also be used as a raw material to synthesize more complex and special properties of substances. Its unique properties may emerge in materials science, providing another possibility for the development of new materials. Therefore, the study of its application field is an important matter to promote progress in many fields.
Research & Development
Yu Taste is dedicated to the research and development of N- [4- [[3-chloro-4- [ (3-fluorophenyl) methoxy] phenyl] amino] -6-quinazolinyl] -2-acrylamide 4-methylbenzene sulfonate. This compound has a delicate structure and unique characteristics, and has great potential in the field of medical exploration.
Initially, its chemical structure was analyzed, the bonding state of each atom was studied in detail, and its spatial configuration was gained to clarify its possible activity check points. Then, its physical and chemical properties, such as solubility and stability, were studied to lay the foundation for subsequent experiments.
During the experiment, carefully select the raw materials, optimize the synthesis path, and strive to improve the yield and purity. After repeated trials, the reaction conditions were improved, and the temperature, pressure, and catalyst dosage were carefully considered.
During the period, despite encountering many obstacles, he adhered to the heart of research and unremitting exploration. There has been some success now, but the road ahead is still long. In the future, we will further explore its biological activity, hoping to contribute to the development of medicine, and promote this compound from research to practical application, benefiting all living beings.
Toxicity Research
Today there is a substance called N- [4- [[3-chloro-4- [ (3-fluorophenyl) methoxy] phenyl] amino] -6-quinazolinyl] -2-acrylamide 4-methylbenzene sulfonate. As a chemical researcher, I focus on its toxicity research.
The structure of this substance is delicate and complex, and its potential toxicity cannot be ignored. To understand its toxicity, multiple experiments are required. Observe its reaction in the organism, observe the change of the cell, and test the function of the organ.
The road to toxicity research, such as the dangerous beach. Or affect the transcription of genes, or disturb the metabolism of cells. Only through careful exploration, scientific method and rigorous attitude can we obtain the truth. Hope to be able to investigate the toxicity of this substance, use it for the world, avoid disasters and enjoy well-being, and ensure the well-being of all beings.
Future Prospects
There is a compound called N- [4- [[3-chloro-4- [ (3-fluorophenyl) methoxy] phenyl] amino] -6-quinazolinyl] -2-acrylamide 4-methylbenzene sulfonate. This compound has a delicate structure and infinite possibilities. Although it is not widely known at the moment, I firmly believe that its future development has great potential.
The way of chemistry is to explore the unknown. The properties and uses of this thing are for us to study in depth. It may emerge in the field of medicine and contribute to the healing of pain; or it may shine in other places such as materials science.
We researchers, with diligence as our wings and wisdom as our lamp, should explore the vast future of this object, open an unknown chapter, and hope that it can shine like a pearl in the sky of science, shining a unique light and achieving unfulfilled expectations.
Where to Buy N-[4-[[3-Chloro-4-[(3-Fluorophenyl)Methoxy]Phenyl]Amino]-6-Quinazolinyl]-2-Propenamide 4-Methylbenzenesulfonate in China?
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Frequently Asked Questions

As a leading N-[4-[[3-Chloro-4-[(3-Fluorophenyl)Methoxy]Phenyl]Amino]-6-Quinazolinyl]-2-Propenamide 4-Methylbenzenesulfonate supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What is the chemical structure of N- [4- [[3-chloro-4- [ (3-fluorophenyl) methoxy] phenyl] amino] -6-quinazolinyl] -2-acrylamide 4-methylbenzenesulfonate
This is a problem of structural analysis of organic compounds. The chemical structure of Ximing "N- [4- [3-cyano-4- [ (3-methoxybenzyl) methoxy] benzyl] amino-6-pyridyl] -2-proparynylbenzoxazole-4-methylbenzylsulfonolactone" needs to be analyzed according to the following steps.
Looking at the main structure, this compound has benzoxazole as the core part. There are 2-proparynyl groups in the 2 positions of benzoxazole, indicating that the proparynyl group is connected to the proparynyl group at the 2 position of the benzoxazole ring through a chemical bond. The proparynyl group contains a carbon-carbon triple bond, which gives the compound a certain reactivity.
Looking at the 4-position again, the 4-methylbenzyl sulfonolactone fragment is connected. In this structure, benzyl is connected to the 4-position of benzoxazole ring, and the counter-position of benzyl has methyl substitution. At the same time, benzyl forms a specific structure with sulfonolactone, which affects the physical and chemical properties of the compound.
Next, the side chain attached to the N atom is complicated. The N atom is connected to the 4- [3-cyano- 4- [ (3-methoxybenzyl) methoxy] benzyl] amino-6-pyridyl fragment. Wherein, the pyridyl group is connected to the above-mentioned amino-containing structure at the 6th position, and the amino group is connected to the benzyl group. The third position of the benzyl group has a cyano group, and the fourth position is modified by [ (3-methoxybenzyl) methoxy]. 3-methoxybenzyl is connected to the fourth position of the benzyl group through an oxygen atom, and the 3-methoxybenzyl group itself has a methoxy group at the third position of the benzyl group.
In summary, the structure of this compound is complex, and each group affects each other to determine its unique physical and chemical properties and reactivity. The synergistic structure of each part makes the compound have specific biological activities, chemical stability and other characteristics, and may have important value in organic synthesis, medicinal chemistry and
What is the main use of N- [4- [[3-chloro-4- [ (3-fluorophenyl) methoxy] phenyl] amino] -6-quinazolinyl] -2-acrylamide 4-methylbenzene sulfonate
N- [4- [[3-cyano-4- [ (3-ethoxy) acetyl] phenyl] amino] -6-pyridyl] -2-methylbenzothiazole-4-acetic acid is an organic compound, which has many important uses in the field of modern medicinal chemistry.
In the process of drug development, one of its important functions is as a key intermediate for active pharmaceutical ingredients (APIs). By specific modification and modification of its chemical structure, new drugs with different pharmacological activities can be created. For example, in the development of anti-tumor drugs, by delicately adjusting the structure of the compound, new agents that exhibit highly selective inhibitory activity on specific tumor cells may be derived, because it can precisely act on some key targets in tumor cells, block tumor cell growth and proliferation signaling pathways, and then curb the rampant growth of tumor cells.
In the field of anti-inflammatory drug development, the compound may play a significant anti-inflammatory effect by modulating the body's inflammatory response-related signaling pathways. For example, inhibiting the excessive release of inflammatory mediators and regulating the activity of immune cells, so as to relieve inflammatory symptoms and provide new opportunities and approaches for the treatment of inflammatory diseases.
In addition, in the process of medicinal chemistry research, this compound acts as an important model molecule, which helps researchers to deeply explore the mechanism of drug-biological target interaction and clarify the structure-activity relationship. By systematically transforming and optimizing its structure, the effects of different substituents and spatial configurations on drug activity, selectivity, and pharmacokinetic properties can be understood, laying a solid theoretical foundation for rational drug design and the creation of new high-efficiency and low-toxicity drugs.
What is the safety of N- [4- [[3-chloro-4- [ (3-fluorophenyl) methoxy] phenyl] amino] -6-quinazolinyl] -2-acrylamide 4-methylbenzene sulfonate
This compound is named N- [4- [3-cyanopropyl) methoxy] phenyl] amino-6-pyridyl] -2-methylfurano [3,4-b] thiophene-4-ylacetic acid, which is a complex organic compound. In terms of its safety, it needs to be carefully analyzed from many aspects.
First, from the perspective of chemical structure, this group contains cyanide groups, which are potentially toxic. Cyanyl groups can release cyanide ions under specific conditions, which can bind to iron ions in cytochrome oxidase, block the respiratory chain of cells, cause hypoxia in cells, cause serious toxicity to organisms, or endanger life.
Secondly, the compound contains many heterocyclic structures, such as furan, thiophene and pyridine rings. Although heterocyclic structures are widely found in various bioactive molecules, some heterocyclic rings may generate toxic or carcinogenic intermediates during metabolism. For example, furan rings are metabolically activated in vivo, or electrophilic intermediates are generated, which covalently bind to biological macromolecules such as DNA and proteins, causing cell damage and mutation.
Furthermore, methoxy, propyl and other substituents in the compound may affect its physical and chemical properties and biological activities. Methoxy can increase the fat solubility of the compound, affecting its absorption, distribution and excretion in the body. If the metabolic pathway is not smooth, or the compound accumulates in the body, it increases the latent risk.
In addition, toxicological experimental data are indispensable for the safety assessment of the compound. Acute toxicity experiments can measure the lethal dose and toxicity symptoms of the organism after a large amount of exposure in a short period of time; subacute and chronic toxicity experiments can explore the effects of long-term low-dose exposure on the organism, including functional damage to the liver, kidneys, nervous system and other important organs, as well as potential carcinogenicity, teratogenicity and mutagenicity.
In short, it is difficult to fully and accurately determine the safety of this compound based on its structure alone, and it is necessary to combine detailed toxicological studies with practical application scenarios. In practical application, it is necessary to strictly follow safety operating procedures and relevant regulatory standards to ensure safety.
What is the market prospect of N- [4- [[3-chloro-4- [ (3-fluorophenyl) methoxy] phenyl] amino] -6-quinazolinyl] -2-acrylamide 4-methylbenzene sulfonate?
Today there is a product named N- [4- [[3-cyanogen-4- [ (3-ethoxyphenyl) ethoxy] phenyl] amino] -6-pyridyl] -2-methylbenzothiazole-4-acetic acid, which is the name of the chemical substance. Let me elaborate on its market prospects.
This product has extraordinary potential in the field of pharmaceutical research and development. At present, the pharmaceutical industry is constantly exploring new compounds in search of effective remedies for diseases. The unique structure of this compound may give it a specific biological activity, which can play a role in targeting certain disease targets. If it can be confirmed by in-depth research and tests that its efficacy is accurate and its safety is good, it will definitely gain a place in the pharmaceutical market.
In the scientific research community, the research on this type of complex structure compound has also attracted much attention. The optimization of its synthesis method and the exploration of the reaction mechanism are all directions for researchers to study. If there can be breakthroughs in synthesis technology, increase yield and reduce costs, it will definitely promote the large-scale preparation and application of this compound and its derivatives, and then expand its market space.
However, its market prospects also pose challenges. The road to drug development is arduous and long, and it requires multiple rounds of rigorous trials and approvals. From laboratory research to clinical application requires a lot of manpower, material resources and time. And the pharmaceutical market is fiercely competitive, with similar or alternative products emerging in an endless stream. If you can't highlight your advantages in efficacy, price, safety, etc., it may be difficult to stand out.
To sum up, N- [4 - [3 - cyano- 4 - [ (3 - ethoxyphenyl) ethoxy] phenyl] amino] - 6 - pyridyl] - 2 - methylbenzothiazole - 4 - acetic acid The market prospect, opportunities and challenges coexist. Only with continuous scientific research innovation and rigorous clinical trials can we open up a broad market.
What are the synthesis methods of N- [4- [[3-chloro-4- [ (3-fluorophenyl) methoxy] phenyl] amino] -6-quinazolinyl] -2-acrylamide 4-methylbenzene sulfonate
To prepare N - [4- [3-cyano-4- [ (3-methoxyphenyl) methoxy] phenyl] amino-6-pyridyl] -2-methylquinoxaline-4-formate ethyl ester, there are many methods, and the following are common synthesis paths:
First, pyridine, quinoxaline and benzene derivatives containing specific substituents are used as starting materials. The specific substituent is introduced before the 6-position of pyridine, which can be achieved by nucleophilic substitution or electrophilic substitution reaction. For example, a suitable halogenated pyridine is reacted with a nucleophilic reagent containing the target substituent in a suitable base and solvent environment, such as potassium carbonate as a base, acetonitrile as a solvent, and heated to reflux, so that the nucleophilic reagent can successfully replace the halogen atom.
The construction of the quinoxaline part is often formed by condensation of o-diamines and dicarbonyl compounds. Such as phthalamine and methyl glyoxal, under acidic catalysis, react in ethanol solvent to form a quinoxaline parent nucleus. Subsequently, by esterification reaction, ethyl ester is introduced at the quinoxaline-4-position, and ethanol and suitable acylating reagents, such as acid chloride or acid anhydride, are esterified under base catalysis.
As for the installation of complex substituents on the benzene ring, a palladium-catalyzed coupling reaction can be used. For example, 4-halo-3-cyanobenzene derivatives and 3-methoxybenzyl alcohol derivatives are reacted in a suitable solvent (such as N, N-dimethylformamide) under the action of palladium catalysts (such as tetra (triphenylphosphine) palladium) and bases (such as cesium carbonate) to achieve the connection of 3-cyano-4- [ (3-methoxyphenyl) methoxy] phenyl substituents. Finally, by condensation reaction, pyridine, quinoxaline and benzene three parts are connected to obtain the target product.
In addition, it can also be synthesized from other key intermediates according to different reaction sequences and conditions. However, regardless of the method, it is necessary to pay attention to the precise control of the reaction conditions, such as temperature, pH, reaction time, etc., in order to increase the reaction yield and selectivity, while taking into account the difficulty of obtaining raw materials and the cost, choose the most suitable method.