Competitive N-{3-Chloro-4-[(3-Fluorobenzyl)Oxy]Phenyl}-6-[5-({[2-(Methylsulfonyl)Ethyl]Amino}Methyl)Furan-2-Yl]Quinazolin-4-Amine Bis(4-Methylbenzenesulfonate) prices that fit your budget—flexible terms and customized quotes for every order.
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What is the chemical structure of N- {3-Chloro-4- [ (3-Fluorobenzyl) Oxy] Phenyl} -6- [5- ({[2- (Methylsulfonyl) Ethyl] Amino} Methyl) Furan-2-Yl] Quinazolin-4-Amine Bis (4-Methylbenzenesulfonate)?
This is the naming of an organic compound. To clarify its chemical structure, it is necessary to disassemble and analyze it according to the naming rules. The name of this compound is long and complicated, and it contains many substituent descriptions. "N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6 - [5- ({[2 - (methylsulfonyl) ethyl] amino} methyl) furan-2-yl] quinazoline-4-amine, bis (4-methylbenzenesulfonate) ".
First look at the main structure, "quinazoline-4-amine" as the core, with a nitrogen-containing group at the 4th position. Among them, the N atom is connected to "3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl", the phenyl group has a chlorine atom at the 3rd position, and a 3-fluorobenzyl group at the 4th position through the oxygen atom. The 6th position is connected to "5- ({[2 - (methylsulfonyl) ethyl] amino} methyl) furan-2-yl", that is, the 2nd position of the furan ring is connected to quinazoline, and the 5th position is connected to a nitrogen-containing group via methylene, and the nitrogen atom is then connected to 2- (methylsulfonyl) ethyl. "Bis (4-methylbenzenesulfonate) " indicates that the compound forms a salt with two molecules of 4-methylbenzenesulfonate.
In ancient Chinese, it is said that this compound is based on quinazoline-4-amine, and the side chain is complicated. The nitrogen atom is connected to an aryl group, and chlorofluorobenzyl is attached in an orderly manner. Hexagonal furan is related to a nitrogen-containing chain through methylene, and the chain end is methylsulfonylethyl. And it forms a salt with two molecules of 4-methylbenzenesulfonic acid. The structure is exquisite and the chemistry is wonderful, which is evident.
What are the main uses of N- {3-Chloro-4- [ (3-Fluorobenzyl) Oxy] Phenyl} -6- [5- ({[2- (Methylsulfonyl) Ethyl] Amino} Methyl) Furan-2-Yl] Quinazolin-4-Amine Bis (4-Methylbenzenesulfonate)?
This is a compound named N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6 - [5 - ({[2 - (methylsulfonyl) ethyl] amino} methyl) furan-2-yl] quinazoline-4-aminobis (4-methylbenzenesulfonate). Looking at its complex structure, such compounds often play a key role in the field of pharmaceutical research and development.
In the exploration of modern medicine, researchers have made great efforts to find those with excellent pharmacological activity by analyzing the characteristics of complex organic compounds. This compound may combine with specific targets in the organism due to its specific chemical structure, thus demonstrating the potential to treat related diseases.
It may be able to regulate or inhibit key biological pathways, receptors or enzymes involved in certain diseases. For example, in cancer treatment research, many complex quinazoline compounds can target specific kinases overexpressed by tumor cells, hindering tumor cell proliferation and survival. Or in neurological disease research, by precisely acting on neurotransmitter receptors or related signaling pathways, improving neurological dysfunction.
Furthermore, in the field of medicinal chemistry, in-depth research on this compound will help to explore the relationship between structure and activity, providing an important basis for subsequent optimization of derived compounds, in order to improve drug efficacy, reduce toxic and side effects, promote the birth of innovative drugs, and bring new hope for human health and well-being.
What are the pharmacological properties of N- {3-Chloro-4- [ (3-Fluorobenzyl) Oxy] Phenyl} -6- [5- ({[2- (Methylsulfonyl) Ethyl] Amino} Methyl) Furan-2-Yl] Quinazolin-4-Amine Bis (4-Methylbenzenesulfonate)?
The name of this medicine is N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6- [5- ({[2- (methylsulfonyl) ethyl] amino} methyl) furan-2-yl] quinazoline-4-aminobis (4-methylbenzenesulfonate). However, I do not know the pharmacological properties of this medicine are detailed in today's classics.
Looking at the ancient medical way, the medicine is mostly based on the taste, return and efficacy of herbs. Although the name of this medicine is well known, it has not been heard of in traditional herbs. If it is deduced from ancient medical theory, the nature of the drug or its components.
The introduction of chlorine, fluorine and other elements, or changing the chemical properties of their substances, affects the development of medicinal power. Aromatic bases such as phenyl and furan groups, also have incense-like medicines in ancient medicines, or have the power of opening orifices and promoting qi. Sulfonate esters, which have no name in ancient times, may be analogous to the genus of sedimentation and dryness.
However, these are all speculative ears. Today's Western medicines have been studied by modern experiments, and their pharmacology is very different from that of ancient medicines. The pharmacological characteristics of this medicine must be carefully studied in modern pharmacological research and clinical trials before we can know its exact work, effect, toxicity, and side effects.
N- {3-Chloro-4- [ (3-Fluorobenzyl) Oxy] Phenyl} -6- [5- ({[2- (Methylsulfonyl) Ethyl] Amino} Methyl) Furan-2-Yl] Quinazolin-4-Amine Bis (4-Methylbenzenesulfonate) What is the production process?
This is a process for preparing N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6- [5- ({[2- (methylsulfonyl) ethyl] amino} methyl) furan-2-yl] quinazoline-4-amine bis (4-methylbenzenesulfonic acid) salt, the steps are as follows:
First take 3-chloro-4-hydroxybenzoic acid, and 3-fluorobenzyl bromide in the presence of a base such as potassium carbonate, with a suitable organic solvent such as N, N-dimethylformamide, heat and stir, and give 3-chloro-4- [ (3-fluorobenzyl) oxy] benzoic acid by nucleophilic substitution reaction. This step requires temperature control and reaction time to ensure a sufficient reaction.
Then the above product is reacted with sulfuryl chloride, converted into the corresponding acid chloride, and then condensed with 2-amino-5- [ (2-methylsulfonylethyl) aminomethyl] furan, in the presence of a suitable acid binding agent such as triethylamine, and reacted in an organic solvent such as dichloromethane to obtain quinazoline derivatives containing furan groups. This process pays attention to the proportion of reagents and reaction conditions to prevent side reactions. The resulting quinazoline derivative is then reduced to a suitable reducing agent such as sodium borohydride in a suitable solvent such as methanol to give N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6- [5- ({[2- (methylsulfonyl) ethyl] amino} methyl) furan-2-yl] quinazoline-4-amine.
Finally, this amine is reacted with 4-methylbenzenesulfonic acid in an appropriate ratio in an alcohol solvent such as ethanol, and N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6- [5- ({[2- (methylsulfonyl) ethyl] amino} methyl) furan-2-yl] quinazoline-4-amine bis (4-methylbenzenesulfonic acid) salt. After the reaction is completed, the target product is obtained after concentration, crystallization, filtration, washing, drying, etc. Each step of the reaction requires fine control conditions, and the product is tested and qualified before entering the next step to obtain a high-purity product.
N- {3-Chloro-4- [ (3-Fluorobenzyl) Oxy] Phenyl} -6- [5- ({[2- (Methylsulfonyl) Ethyl] Amino} Methyl) Furan-2-Yl] Quinazolin-4-Amine Bis (4-Methylbenzenesulfonate) market prospects?
Today there is a product called N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6- [5- ({[2- (methylsulfonyl) ethyl] amino} methyl) furan-2-yl] quinazoline-4-aminobis (4-methylbenzenesulfonate). Looking at the market prospect of this product, it is like a cloud in the sky, hazy and yet to be seen.
From the perspective of the field of pharmaceutical research and application, such compounds are often involved in the development of innovative drugs. At a time when medical technology is advancing rapidly, the demand for new anti-cancer and antiviral drugs is like thirst. If this compound has unique pharmacological activity and can accurately target disease targets, its prospects will be as bright as spring flowers. Just like the appearance of artemisinin in the past, it has opened up a new path for malaria treatment. If this product also has such magical effects, it must be pursued by pharmaceutical companies and invested in research and development. The market potential will be like a torrent, unlimited.
However, its journey is not smooth. The road to new drug research and development is full of dangers, just like the difficulty of Shu Dao. From the laboratory to the clinic, it needs to go through layers of rigorous tests, pharmacological and toxicological research, clinical trials, etc., and any link is like a hero. And the market competition is fierce, and similar competitors are also like Lin Erli. If you can't stand out in terms of efficacy, safety, cost, etc., you may be like a meteor across the night sky. Although it shines for a while, it is difficult to last forever.
Looking at the chemical raw material market again, if its synthesis process is simple and the cost is controllable, it may add a high-quality raw material to chemical production. However, the chemical market is changing, and factors such as policies and regulations, and fluctuations in raw material prices are like storms, affecting its market foothold.
In summary, the market prospect of N- {3-chloro-4- [ (3-fluorobenzyl) oxy] phenyl} -6- [5- ({[2- (methylsulfonyl) ethyl] amino} methyl) furan-2-yl] quinazoline-4-aminobis (4-methylbenzenesulfonate), opportunities and challenges coexist, such as seeing flowers in the fog, it is necessary to clear the fog and prudent insight to clarify its future direction.