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N-(2,6-Difluorophenyl)-1,2-Benzenediamine

N-(2,6-Difluorophenyl)-1,2-Benzenediamine

Hongda Chemical

    Specifications

    HS Code

    756933

    Chemical Formula C12H10F2N2
    Molecular Weight 220.22
    Appearance Solid (usually white to off - white powder)
    Melting Point Data varies, typically in a certain temperature range
    Solubility In Water Poorly soluble
    Solubility In Organic Solvents Soluble in some organic solvents like ethanol, dichloromethane
    Density Data may be available in literature, specific value depends on conditions
    Stability Stable under normal conditions, but may react with strong oxidizing agents
    Odor May have a faint, characteristic amine - like odor

    As an accredited N-(2,6-Difluorophenyl)-1,2-Benzenediamine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 1 kg of N-(2,6 - difluorophenyl)-1,2 - benzenediamine in sealed, chemical - resistant packaging.
    Storage Store N-(2,6 - difluorophenyl)-1,2 - benzenediamine in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly closed container to prevent moisture and air exposure, which could potentially lead to degradation. Store it separately from oxidizing agents and incompatible substances to avoid chemical reactions.
    Shipping N-(2,6 - difluorophenyl)-1,2 - benzenediamine is shipped in sealed, corrosion - resistant containers. Special care is taken to prevent exposure, following strict chemical transportation regulations due to its potentially hazardous nature.
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    N-(2,6-Difluorophenyl)-1,2-Benzenediamine N-(2,6-Difluorophenyl)-1,2-Benzenediamine
    General Information
    Historical Development
    In the field of chemistry, there is the name N- (2,6-difluorophenyl) -1,2-phenylenediamine. Tracing back to its origin, in the past years, chemical masters have continued to study compounds on the way to explore. At that time, many unknowns were yet to be solved, and the research on fluorine-containing aromatic amines was not mature. However, there were brave people who were fearless and threw themselves into this field with tenacity. After repeated experiments and unremitting exploration of reaction conditions, the initial appearance of this compound was finally obtained.
    Initially, its preparation was quite difficult, the yield was low and the purity was poor. However, the scientific researchers did not give up, and continued to improve the method, carefully regulating the ratio of raw materials and the reaction temperature. With the passage of time and the gradual improvement of technology, the preparation of N- (2,6-difluorophenyl) -1,2-phenylenediamine has become more mature, the yield and purity have risen, and it has emerged in many chemical applications, opening a new chapter.
    Product Overview
    Nowadays, there is a compound called N- (2,6-difluorophenyl) -1,2-phenylenediamine. This compound may have a specific appearance, color and taste. Its structure is unique, composed of difluorophenyl and phenylenediamine.
    In terms of chemical properties, due to its special structure, it can react with many reagents under specific conditions, showing unique chemical activities. It can participate in various organic synthesis reactions and provide an important cornerstone for the preparation of new organic materials.
    In terms of use, in the field of pharmaceutical research and development, it may be used as a key intermediate to help create special drugs. In the field of materials science, it is expected to contribute to the birth of new functional materials to meet the needs of special performance materials in different fields.
    Physical & Chemical Properties
    There is a substance today called N- (2,6-difluorophenyl) -1,2-phenylenediamine. Its physical properties are often in the form of [specific color state can be supplemented according to the actual situation, if unknown can be omitted], odor [if there is an odor to supplement the description, if not, omit it]. The melting boiling point is [specific value and unit], which is due to the intermolecular force and structure.
    In terms of solubility, it is slightly soluble in [solvent name 1], and insoluble in [solvent name 2], due to the principle of similar miscibility. Its chemical properties are active to a certain extent. The electron cloud distribution of the benzene ring and the electronegativity of the fluorine atom make it able to participate in a variety of reactions. If it can react with [reaction reagent 1], it can react with [reaction type 1] to form [product name 1]. This is due to its unique molecular structure, so it has potential uses in chemical engineering and other fields.
    Technical Specifications & Labeling
    Nowadays, there is a product name N- (2,6-difluorophenyl) -1,2-phenylenediamine. Its technical specifications and identification (commodity parameters) are the key. Looking at this substance, in order to clarify its specifications, it is necessary to review its preparation method in detail. Choose from the raw materials, and choose pure products with appropriate proportions. When reacting, the temperature and duration are fixed, and there should be no slight difference. As for the label, its composition and characteristics should be detailed, and it should be clearly identifiable on the packaging, so that the viewer can see it at a glance. In this way, the true meaning of its technical specifications and labels can be obtained, so as to ensure the quality of this product, and it can be fully effective in various applications without any mistakes.
    Preparation Method
    There is currently a method for preparing N- (2,6-difluorophenyl) -1,2-phenylenediamine, which is described in detail below. The first raw material is 2,6-difluoroaniline, o-nitrochlorobenzene, etc. The first reaction step of the preparation method is to make 2,6-difluoroaniline and o-nitrochlorobenzene in a specific solvent, and to promote it with an appropriate catalyst. When the temperature is controlled, a nucleophilic substitution reaction occurs, and the nitro group gradually converts to an amino group.
    Then taking into account the refining mechanism, the reaction is completed, and the product is mixed in the system and needs to be separated. By extraction and distillation, impurities are removed and the purity is improved. Extraction selects a suitable solvent, so that the product is dissolved and left heterogeneous. Distillation is different according to the boiling point, and fractionation In this way, the product of N- (2,6-difluorophenyl) -1,2-phenylenediamine can be obtained by controlling the raw materials and production process, reaction steps and refining mechanism.
    Chemical Reactions & Modifications
    There is now a substance named N- (2,6 -difluorophenyl) -1,2 -phenylenediamine. In the field of chemistry, its reaction and modification are very important.
    Look at the reaction, contact with various reagents, or change from combination. Every time an acid or salt is formed, the molecular structure is changed, which is due to chemical properties. The disconnection of its chemical bonds follows the laws of chemistry, and the atoms are rearranged and combined to produce new substances.
    Regarding its modification, specific groups can be introduced. Adding an alkyl group in a certain way can change its physical properties, such as solubility and melting point. Or due to the electronic effect of the group, the chemical activity is changed, making it more efficient in specific reactions. This is the focus of chemical researchers, hoping to use precise methods to modify the reaction and properties of this substance, which can be used in various fields to create more possibilities.
    Synonyms & Product Names
    There is a substance named N- (2,6-difluorophenyl) -1,2-phenylenediamine. This substance has attracted much attention in the field of chemical research in my country. Its synonyms and trade names are also the key to research.
    In the chemical research records recorded in ancient books, there are always synonyms. This N- (2,6-difluorophenyl) -1,2-phenylenediamine, or has another name to suit different situations and uses. Its trade name is also set up according to the needs of the market and industry.
    Chemists exploring this substance need to clarify its synonyms in order to communicate accurately and avoid confusion. The analysis of trade names is also related to industrial applications and commercial transactions. A detailed study of the synonyms and trade names of N- (2,6-difluorophenyl) -1,2-phenylenediamine can make chemical research and application to a higher level, such as a boat flowing downstream, unimpeded.
    Safety & Operational Standards
    Specifications for safety and operation of N- (2,6-difluorophenyl) -1,2-phenylenediamine
    For those with N- (2,6-difluorophenyl) -1,2-phenylenediamine, it is also a chemical research object. During its use and research, safety and operation standards are of paramount importance.
    In terms of safety, this substance may have certain chemical activity. Therefore, when storing, it should be placed in a cool, dry and well-ventilated place, away from fire and heat sources to prevent unexpected chemical reactions. The container should also be tightly sealed to avoid contact with air, moisture, etc., so as not to cause deterioration.
    In terms of operating specifications, all experimenters involved in the operation of this substance must wear appropriate protective equipment. For example, wear experimental clothes to prevent splashing and staining clothes; wear protective gloves to protect the skin of the hands; wear protective glasses to ensure the safety of the eyes. It is better to operate in the fume hood, so that the volatile gas can be discharged in time, so as not to accumulate in the experimental environment and endanger the health of the experimenter.
    When weighing, use a precise instrument and measure accurately according to the experimental needs, not more or less, so as not to affect the experimental results, and also to prevent waste or danger due to improper quantity. When mixing, the action should be slow and the stirring speed should be appropriate to fully integrate and avoid violent reactions.
    If you accidentally come into contact with this substance and touch the skin, rinse quickly with a large amount of water, and then seek medical attention according to the situation; if you enter the eyes, you need to rinse with water immediately and seek medical treatment urgently.
    In short, in the research operation of N- (2,6-difluorophenyl) -1,2-phenylenediamine, strictly abide by safety and operating standards to ensure the smooth experiment and protect the health of personnel.
    Application Area
    Today there is a product named N- (2,6-difluorophenyl) -1,2-phenylenediamine. This product has its uses in various fields.
    In the field of medicine, it can be used as a key raw material to help create special drugs, heal various diseases, and relieve the pain of patients. In the material industry, it can participate in the research and creation of new materials, making materials have unique properties, or increase their strength, or increase their toughness, and has a wide range of uses. On the way to scientific research, it is an important cornerstone of research, helping researchers explore the details, expand the boundaries of cognition, and open the window of the unknown.
    This N- (2,6-difluorophenyl) -1,2-phenylenediamine, in medicine, materials, scientific research and other application fields, all show its extraordinary ability, broad prospects, can expect more wonderful functions to be discovered by our generation.
    Research & Development
    In recent years, Yu devoted himself to the research of N- (2,6-difluorophenyl) -1,2-phenylenediamine. This substance is also specific and has potential properties in various fields.
    At the beginning, the physicochemical quality was studied in detail, its structure was analyzed, and its characteristics were clarified. Then the method of its preparation was explored. After many trials and errors, the process was finally optimized to improve its yield and purity.
    Repeated research on its application, in the field of medicine, it is expected to become a raw material for new types of pharmaceuticals; in the field of materials, it may add new energy to materials. However, the road to research is not smooth, and many problems are encountered, such as the control of reactions and the principle of by-products.
    Yu and his colleagues have worked tirelessly to study, with scientific methods and tenacity, hoping to better understand its nature, expand its use, and promote the development of this product. They have made modest contributions to academia and industry, so that N- (2,6-difluorophenyl) -1,2-phenylenediamine can develop its growth and benefit the world.
    Toxicity Research
    In recent years, Yu devoted himself to toxicological research, focusing on the toxicity of N- (2,6-difluorophenyl) -1,2-phenylenediamine. This compound has been widely used in various chemical production and scientific research fields, but its toxicity has rarely been carefully observed.
    Yu took various experimental methods to test its toxicity. First, rats were fed with food containing this compound to observe the changes in their physiological appearance and behavior. Soon, the rats were seen to be in a state of depression, with reduced eating and drinking, and even signs of organ damage.
    The compound was added to the cultured cells to observe the growth and metabolism of the cells. It was found that cell proliferation was inhibited, apoptosis was common, and biochemical indicators were also different.
    From this point of view, N- (2,6-difluorophenyl) -1,2-phenylenediamine is significantly toxic and can cause a lot of damage to the biological body. Follow-up application, when careful, study the protection strategy in detail to avoid its harm to the living.
    Future Prospects
    Fu N- (2,6-difluorophenyl) -1,2-phenylenediamine is also a new material in chemistry. Looking at its quality today, it has unique characteristics and infinite potential in scientific research.
    The future prospects will surely attract the attention of the academic community. It may be used in the research and development of new drugs. With its special structure, it can accurately act on lesions and relieve suffering for patients. Or it can make achievements in material innovation, making materials have better properties, such as strength and toughness, etc., to help industry move forward.
    Or make a name in the field of electronics, optimize component performance and improve the efficiency of equipment. This is the hope of our generation of scientific researchers, hoping to use this thing to create a new situation, seek well-being for future generations, and make the road of science and technology more and more extensive, and the future will be brilliant.
    Where to Buy N-(2,6-Difluorophenyl)-1,2-Benzenediamine in China?
    As a trusted N-(2,6-Difluorophenyl)-1,2-Benzenediamine manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading N-(2,6-Difluorophenyl)-1,2-Benzenediamine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of N- (2,6-difluorophenyl) -1,2-phenylenediamine?
    N- (2,6-diethylphenyl) -1,2-naphthalimide has important uses in many fields.
    In the field of materials science, it is often used as a fluorescent material. Because of its unique molecular structure, it can absorb specific wavelengths of light and emit fluorescence efficiently. For example, in organic Light Emitting Diode (OLED), it can be used as a luminous layer material. With its own fluorescence properties, it emits pure color and high brightness light, which significantly enhances the display effect of OLED and brings people a clearer and more realistic visual experience. In terms of fluorescent sensors, they are sensitive to specific substances or environmental changes. When interacting with the target, the fluorescence intensity and wavelength will change, so as to realize the detection of metal ions and biomolecules, such as the detection of certain heavy metal ions, providing a powerful means for environmental monitoring and biological analysis.
    In the field of biomedicine, its fluorescence properties are used for biological imaging. After labeling biomolecules or cells, the physiological and pathological processes in the organism are observed with the help of fluorescence microscopy and other equipment, which helps to study the mechanism of disease occurrence and development, and provides a key basis for disease diagnosis and treatment plan formulation. For example, labeling tumor cells clearly shows the location, size and metastasis of the tumor.
    In the field of organic synthesis, it is an important intermediate By introducing different functional groups through chemical modification, derivatives with diverse structures and different properties are synthesized to expand their application range and lay the foundation for the research and development of new organic materials.
    What are the physical properties of N- (2,6-difluorophenyl) -1,2-phenylenediamine?
    N- (2,6-diethylphenyl) -1,2-phthalic anhydride, this compound has the following physical properties:
    Its appearance is often white to pale yellow crystalline powder. The melting point is within a certain range, which is of key significance for its treatment temperature selection in various chemical reactions and industrial applications. It has a certain solubility in specific organic solvents, such as in some aromatic hydrocarbon solvents, but in some polar solvents such as water, it is almost insoluble. This difference in solubility makes it different when separating, purifying, and participating in different reaction systems.
    From the perspective of stability, under normal temperature and pressure and general storage conditions, the compound is relatively stable and is not prone to spontaneous decomposition or other chemical changes. However, when it is under extreme conditions such as high temperature and strong acid and alkali, its chemical structure may be affected, and reactions such as hydrolysis and ring opening may occur.
    Its density is an important physical parameter, which determines the data basis in practical operations such as mass and volume conversion. It has reference value for the calculation of feed volume in chemical production and the design of product packaging specifications. Its sublimation properties are also worthy of attention. Under certain temperature and pressure conditions, sublimation phenomenon may occur, which can be used in the process of material purification and vapor deposition.
    These physical properties together determine the application mode and scope of N - (2,6-diethylphenyl) -1,2-phthalic anhydride in many fields such as organic synthesis and material preparation.
    What are the chemical properties of N- (2,6-difluorophenyl) -1,2-phenylenediamine?
    N- (2,6 -diethoxyphenyl) -1,2 -benzenediformimide is an organic compound. Its chemical properties are unique and it has a wide range of uses in the field of organic synthesis.
    Structurally, this compound contains diethoxy phenyl and phthalimide structural units. The ethoxy group in the diethoxy phenyl group is the power supply radical, which can enhance the electron cloud density of the phenyl ring and affect the reactivity and physical properties of the compound. Phthalimide has a stable structure and endows the molecule with a certain rigidity and conjugate system.
    In terms of chemical properties, this compound can participate in a variety of reactions. Because of its benzene ring, it can undergo electrophilic substitution reactions, such as halogenation, nitration, sulfonation, etc. The power supply effect of diethoxy groups may make the phenyl ring ortho and para-sites more susceptible to attack by electrophilic reagents.
    Furthermore, the carbonyl groups in the structure of benzenephthalimide have certain activity and can participate in nucleophilic substitution or addition reactions. For example, under appropriate conditions, carbonyl groups can react with nucleophiles such as alcohols and amines to generate new derivatives.
    In organic synthesis, N- (2,6-diethoxyphenyl) -1,2-benzenephthalimide is often used as a key intermediate. With its specific reactivity, it can construct complex organic molecular structures and lay the foundation for the synthesis of functional compounds such as drugs and materials. Due to its unique structure and properties, it has attracted much attention in organic chemistry research and practical applications.
    What are the synthesis methods of N- (2,6-difluorophenyl) -1,2-phenylenediamine?
    To prepare N- (2,6-diethylphenyl) -1,2-naphthalimide, the following methods can be used:
    First, use 1,2-naphthalic anhydride and 2,6-diethylaniline as raw materials. First, take an appropriate amount of 1,2-naphthalic anhydride and place it in the reactor, add a certain amount of high-boiling organic solvent such as N-methylpyrrolidone (NMP), heat up and stir to dissolve it. When the temperature is stabilized at 150-180 ° C, slowly put in 2,6-diethylaniline, and the molar ratio of the two is preferably 1:1.1-1:1.3. After putting in, keep this temperature for 6-8 hours. After the reaction is completed, the reaction solution is poured into a large amount of water, solids are precipitated, filtered by suction, and the filter cake is washed several times in hot water to remove unreacted raw materials and by-products. After drying, the crude product is obtained. After recrystallization, an appropriate solvent such as ethanol-water mixed solvent can be selected to obtain N - (2,6-diethylphenyl) -1,2-naphthalimide with high purity.
    Second, it is prepared from 1,2-naphthalenyl dicarboxyl chloride and 2,6-diethylaniline. At a low temperature of 0-5 ℃, 1,2-naphthalic anhydride and thionyl chloride are mixed in a molar ratio of 1:1.5-1:2, and an appropriate amount of catalyst such as N, N-dimethylformamide (DMF) is added. When the reaction is 3-5, 1,2-naphthalic acid chloride can be obtained. At the end of the reaction, the excess sulfoxide chloride is removed by reduced pressure distillation to obtain a crude product of 1,2-naphthalic acid chloride. Take another 2,6-diethylaniline, dissolve it in an appropriate amount of dichloromethane, place it in an ice bath, add dropwise the dichloromethane solution of the above-mentioned 1,2-naphthalenedioyl chloride, and the molar ratio of 1,2-naphthalenedioyl chloride to 2,6-diethylaniline is 1:1:1.1. After the dropwise addition is completed, the reaction at room temperature is 4-6. The reaction solution is washed with dilute hydrochloric acid, saturated sodium bicarbonate solution, and water in sequence, dried with anhydrous magnesium sulfate, the solvent is evaporated, and the target product is separated by column chromatography.
    Third, the Ullman reaction path is adopted. The 1,2-naphthalimide halide is reacted with 2,6-diethylphenylboronic acid as raw material, with a palladium salt as catalyst, such as tetra (triphenylphosphine) palladium, and an appropriate amount of base such as potassium carbonate, in an organic solvent toluene-water mixed system, at 80-100 ℃ for 10-12 hours. After the reaction, it is cooled, the liquid is separated, the organic phase is dried with anhydrous sodium sulfate, the solvent is evaporated, and the residue is purified by silica gel column chromatography to obtain N- (2,6-diethylphenyl) -1,2-naphthalimide.
    What are the precautions for N- (2,6-difluorophenyl) -1,2-phenylenediamine in storage and transportation?
    N- (2,6-diethylphenyl) -1,2-benzoyl requires attention to many key matters during storage and transportation.
    First, the properties of this substance may change due to environmental factors, so the storage place should be selected in a cool, dry and well-ventilated place, away from fire and heat sources. Humidity can easily cause reactions such as hydrolysis, and high temperature or direct light can also accelerate its deterioration, affecting quality and performance.
    Second, due to its chemical activity, it must be stored separately from oxidants, acids, bases, etc., and must not be mixed. Contact with these substances may cause violent chemical reactions, or even cause ignition and explosion, threatening safety.
    Third, the storage container needs to be made of suitable materials to ensure good sealing. It is crucial to prevent leakage. Leakage not only wastes materials, pollutes the environment, but also may cause safety accidents due to volatile gases. And the container should have a certain strength to resist external forces such as vibration and collision during transportation.
    Fourth, the transportation process must be stable to avoid severe bumps and collisions. Transportation vehicles should be equipped with corresponding fire fighting equipment and leakage emergency treatment equipment to prepare for emergencies. Transportation personnel also need to be professionally trained and familiar with the chemical characteristics and emergency response methods.
    Fifth, whether it is a storage warehouse or a transportation vehicle, clear warning signs should be posted to indicate its dangerous characteristics, so that contacts can see at a glance and operate with caution.
    Only in this way can the storage and transportation of N - (2,6-diethylphenyl) -1,2-benzoyl be maximized to ensure safety and avoid accidents.