As a leading N-(1,5-Dimethyl-3-Oxo-2-Phenyl-2,3-Dihydro-1H-Pyrazol-4-Yl)-4-Fluorobenzenesulfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical structure of N- (1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-yl) -4-fluorobenzenesulfonamide
The structure of this compound is explained as follows according to the naming rules: the main chain contains nitrogen atoms, and mentions "1,5-dimethyl-3-oxo-2-benzyl-2,3-dihydro-1H-indole-4-yl", which can be seen as indole ring as the main structure part. 1,5-Dimethyl indicates that there is a methyl group at the 1st and 5th positions of the indole ring; 3-oxo means that there is a carbonyl group at the 3rd position; 2-benzyl is connected to the benzyl group at the 2nd position; 2,3-dihydrogen means that the double bond hydrogenation between the 2nd and 3rd positions of the indole ring; 1H-indole clear ring has a hydrogen atom at the 1st position. And 4-group means that the main structure of the indole ring is connected to other groups at the 4th position. This group is "4-fluorobenzoxy carbonyl", that is, the structure formed by connecting the fluorobenzyl group to the carbonyl group at the 4th position is connected to the indole ring.
Overall, this compound is composed of indole ring as the core, connecting different substituents at specific positions, and each substituent gives the compound unique chemical properties and spatial structure. By integrating the information in each part of the nomenclature, a relatively accurate chemical structure of the compound was constructed.
What are the main uses of N- (1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-yl) -4-fluorobenzenesulfonamide
N- (1,5-dimethyl-3-oxo-2-benzyl-2,3-dihydro-1H-indole-4-yl) -4-fluorobenzyl sulfonamide is an organic compound. This compound is widely used in the field of medicinal chemistry, and its main uses are as follows:
First, it is used in drug development. Because of its unique chemical structure, it can be used as a lead compound. After structural modification and optimization, it is expected to develop new drugs. In the development of anti-tumor drugs, its specific structure may interact with tumor cell targets to inhibit tumor cell growth and proliferation, providing novel ideas and approaches for the creation of anti-cancer drugs.
Second, in the field of organic synthesis, it can be used as a key intermediate. With its diverse activity check points in its structure, it can build more complex organic molecular structures through various organic reactions, providing a powerful tool for the synthesis of organic materials with specific functions and the total synthesis of natural products. For example, by reacting with other compounds containing specific functional groups, complex molecular skeletons can be constructed, and then organic compounds with special properties or biological activities can be obtained.
Third, it is of great significance in the study of biological activity. Researchers can explore the biological activity of the compound, clarify its mechanism of action with specific targets in organisms, and deeply understand the relevant physiological and pathological processes. For example, studying its effect on specific enzyme activities or binding patterns with receptors provides a basis for elucidating the nature of life activities and the mechanism of disease occurrence and development, thus laying a theoretical foundation for drug design and development.
What is the synthesis method of N- (1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-yl) -4-fluorobenzenesulfonamide
To prepare N- (1,5-dimethyl-3-oxo-2-furyl-2,3-dihydro-1H-pyrrole-4-yl) -4-bromobenzamide, the following ancient method can be used.
Take an appropriate 1,5-dimethyl-3-oxo-2-furyl-2,3-dihydro-1H-pyrrole-4-amine and place it in a clean reactor. Measure an appropriate amount of halogenating reagents, such as hydrobromic acid or brominating agent, and slowly add them to the kettle. Control the reaction temperature to a suitable range, either warm or cool, depending on the needs of the specific reaction, and stir at the same time to make the reactants fully mixed. The purpose of this step is to brominate the amine group to obtain a bromine-containing intermediate.
Take another 4-bromobenzoic acid, and place it in another reaction vessel with an appropriate condensation agent, such as carbodiimide condensation agent, and add an appropriate amount of organic solvent to dissolve the two evenly. Then pour the bromine-containing intermediate carefully into the mixture, raise the temperature, and maintain the reaction for a period of time. During this period, pay close attention to the reaction process, which can be monitored by thin-layer chromatography or other suitable analytical methods. This condensation reaction aims to connect the bromine-containing intermediate with 4-bromobenzoic acid to form N- (1,5-dimethyl-3-oxo-2-furyl-2,3-dihydro-1H-pyrrole-4-yl) -4-bromobenzamide.
After the reaction is completed, the reaction mixture is cooled to room temperature. Then, according to the nature of the product and the impurities, separate and purify. Or by extraction, the product is extracted with a suitable organic solvent to separate the impurities; or by column chromatography, the appropriate stationary phase and mobile phase are selected to separate the product from the impurities. Finally, through concentration, crystallization and other operations, pure N- (1,5-dimethyl-3-oxo-2-furyl-2,3-dihydro-1H-pyrrole-4-yl) -4-bromobenzamide can be obtained. The whole process needs to be handled with caution and attention should be paid to the control of reaction conditions to obtain satisfactory yield and purity.
What are the physical properties of N- (1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-yl) -4-fluorobenzenesulfonamide
N- (1,5-dimethyl-3-oxo-2-benzyl-2,3-dihydro-1H-indole-4-yl) -4-fluorobenzamide, which is an organic compound. Its physical properties are quite important and are related to many practical applications.
Looking at its appearance, it is often white to light yellow crystalline powder at room temperature and pressure. This color and morphology are easy to identify and process in experiments and production scenarios. Its melting point is in a specific range, generally speaking, about [X] ° C. The determination of the melting point is of great significance for the identification of purity. The higher the purity, the closer the melting point is to the theoretical value.
Solubility is also a key property. In organic solvents, such as dichloromethane, N, N-dimethylformamide, it exhibits good solubility, which is conducive to acting as a reactant or product in organic synthesis reactions, and is convenient for the construction, separation and purification of reaction systems. However, the solubility in water is very small, which is closely related to the large proportion of hydrophobic groups in its molecular structure.
The density of this compound is about [X] g/cm ³, and the density value is indispensable in the material measurement and equipment design involved in chemical production. In addition, its stability is good under normal conditions, but when exposed to strong oxidizing agents, strong acids or strong bases, the structure may change and chemical reactions may occur. Therefore, care must be taken to avoid contact with such substances during storage and use.
The combination of these physical properties lays the foundation for the application of N- (1,5-dimethyl-3-oxo-2-benzyl-2,3-dihydro-1H-indole-4-yl) -4-fluorobenzamide in organic synthesis, drug research and development, etc. Scientists and producers can rationally design reaction paths, optimize production processes, and plan storage and transportation methods according to their properties.
What is the market price of N- (1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-yl) -4-fluorobenzenesulfonamide
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