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N-(1,3-Benzodioxol-5-Ylmethyl)-4-Fluorobenzenesulfonamide

N-(1,3-Benzodioxol-5-Ylmethyl)-4-Fluorobenzenesulfonamide

Hongda Chemical

    Specifications

    HS Code

    815203

    Chemical Formula C15H12FNO4S
    Molecular Weight 323.32
    Appearance Solid (predicted)
    Boiling Point 500.8±60.0 °C at 760 mmHg (predicted)
    Melting Point 184 - 188 °C
    Logp 3.09 (predicted)
    Pka 10.42±0.70 (predicted)
    Solubility Soluble in DMSO, sparingly soluble in water
    Density 1.471±0.06 g/cm3 (predicted)
    Flash Point 256.7±32.9 °C (predicted)

    As an accredited N-(1,3-Benzodioxol-5-Ylmethyl)-4-Fluorobenzenesulfonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100 - gram pack of N-(1,3 - benzodioxol - 5 - ylmethyl)-4 - fluorobenzenesulfonamide in sealed container.
    Storage Store N-(1,3 - benzodioxol - 5 - ylmethyl)-4 - fluorobenzenesulfonamide in a cool, dry place away from heat sources and direct sunlight. Keep it in a tightly sealed container to prevent moisture absorption and contamination. Store it separately from incompatible substances, such as strong oxidizing agents or bases, to avoid chemical reactions.
    Shipping Ship N-(1,3 - benzodioxol - 5 - ylmethyl)-4 - fluorobenzenesulfonamide with proper chemical - grade packaging. Ensure compliance with regulations for chemical shipping, using appropriate carriers and labeling for safe transit.
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    N-(1,3-Benzodioxol-5-Ylmethyl)-4-Fluorobenzenesulfonamide N-(1,3-Benzodioxol-5-Ylmethyl)-4-Fluorobenzenesulfonamide
    General Information
    Historical Development
    The historical development of N- (1,3-benzodioxacyclopentene-5-ylmethyl) -4 -fluorobenzenesulfonamide is related to the process of chemical exploration. In the past, many chemists worked tirelessly on molecular structure and properties. At first, the understanding of complex organic structures was still shallow, but with the evolution of technology and the deepening of exploration, this compound was finally obtained. After repeated experiments, researchers analyzed its components and gained insight into the reaction mechanism, from ignorance to clarity. This compound has gradually emerged from obscurity in the world, gradually emerging in the fields of medicine, materials and other fields, expanding a new path for subsequent scientific research. Its development is a shining chapter in the history of chemistry, reflecting the thirst for knowledge and the state of chemists.
    Product Overview
    Product Overview
    There is a product called N- (1,3-benzodioxane-5-ylmethyl) -4 -fluorobenzenesulfonamide. Its shape is either powder or crystalline, with pure color and uniform quality.
    The synthesis of this product requires several steps of reaction. First take 1,3-benzodioxane-5-formaldehyde, react with specific reagents, and introduce key groups. After reacting with 4-fluorobenzenesulfonyl chloride, it is controlled by a series of conditions to obtain this product.
    In terms of properties, it has certain stability and good solubility in specific solvents. In the field of medicine, studies have found that it has potential affinity for certain disease-related targets, or can be used as lead compounds for further development into therapeutic agents for the well-being of patients, but more in-depth research and verification are needed.
    Physical & Chemical Properties
    Today there is a substance called N- (3-Benzodioxol-5-Ylmethyl) -4-Fluorobenzenesulfonamide. Its physical and chemical properties are related to the gist of our research. The color state of this substance, or its solid state, and whether the texture is delicate or not, need to be carefully observed. The geometry of its melting point is related to its thermal change, which is a key parameter in experimental operations.
    Solubility is also an important characteristic. In various solvents, the difficulty of dissolution has its own rules. The chemical activity of this substance and the reaction with surrounding substances can be traced. Whether its structure is stable or not depends on its preservation and application. We use scientific methods to explore its nature, hoping to clarify its essence, and lay a solid foundation for subsequent use, so as to make the best use of everything and live up to the power of research.
    Technical Specifications & Labeling
    Today there is a thing called N- (3-Benzodioxol-5-Ylmethyl) -4-Fluorobenzenesulfonamide. To clarify its technical specifications and identification (commodity parameters), it is necessary to study it in detail with ancient methods.
    To make this thing, its technical specifications must abide by the rules. The selection of raw materials must be pure, and the proportion of each ingredient should be consistent with mathematics. The temperature of the reaction should not be slightly different. In this way, you can get a product with uniform texture and high quality.
    As for the identification (commodity parameters), it is necessary to specify its characteristics, content and purity. In order to make it visible to everyone, so that the quality is known. If the character is any, the color and state should be clear; the content geometry, the exact value is indispensable; the purity is also the key. This is the key to the identification (commodity parameters) and cannot be ignored. In accordance with the technical specifications and labeling (product parameters) regulations, this product can be recognized by people in the market and travel freely.
    Preparation Method
    To prepare N- (1,3-benzodioxane-5-ylmethyl) -4 -fluorobenzenesulfonamide, the raw materials, production process, reaction steps and catalytic mechanism are the key.
    The starting materials are selected from high-quality 1,3-benzodioxane and 4-fluorobenzenesulfonyl chloride. First, 1,3-benzodioxane and halogenated hydrocarbons are catalyzed by alkali, and the corresponding substitutes are obtained by nucleophilic substitution.
    Then, 4-fluorobenzenesulfonyl chloride and a specific amine are acylated in a suitable solvent and temperature to form a key intermediate. This intermediate is then reacted with the previously obtained substitute, and with the help of a phase transfer catalyst, through condensation, the target product is obtained.
    The reaction steps require precise temperature control, speed regulation, and attention to the reaction time. In terms of catalytic mechanism, the selected base and phase transfer catalyst can effectively reduce the reaction activation energy, improve the reaction rate and yield, so that pure N- (1,3-benzodioxacyclopentene-5-ylmethyl) -4 -fluorobenzenesulfonamide can be obtained.
    Chemical Reactions & Modifications
    There is now a substance named N- (3-Benzodioxol-5-Ylmethyl) -4-Fluorobenzenesulfonamide. In the field of chemistry, its reaction and modification are crucial.
    Looking at its reaction, various conditions affect it. The rise and fall of temperature, the characteristics of solvents, and the presence or absence of catalysts can all make the reaction path, rate, and quality and quantity of the product different. Or because the temperature is too high, the reaction is too fast and the by-product is clumped; or because the solvent is not suitable, the reaction is blocked.
    As for modification, it is designed to give it novelty. Or change its molecular structure, increase its stability and activity, or adjust its solubility and reactivity. By exquisite design, it is more effective in specific scenarios.
    Chemists are in the meantime, studying the truth to achieve perfection, hoping that this product can be used in the pharmaceutical and material industries, and can be used by the world.
    Synonyms & Product Names
    N- (1,3-benzodioxane-5-ylmethyl) -4 -fluorobenzenesulfonamide, in the field of chemistry, is related to many synonymous names and commodity names. In ancient learning, if you want to clarify a medicine and a substance, you must first name it. This substance also has various nicknames, all of which are used by scholars and researchers to distinguish its nature and use it.
    Although it is a newly created chemical compound, it is similar to the ancient Materia Medica, and it is passed down by name. Or because of its exquisite structure, it is like an ancient rare structure, so it has a specific synonymous name to express its unique molecular structure. Or because of its use, it is similar to some ancient healing things, and it gets the name of a commodity, hoping to develop its effectiveness in medicine and other industries.
    Today's research on this thing is to distinguish its synonymous name and the name of the commodity. The pharmacists of ancient times studied the names of various medicines in the compendium of Materia Medica in detail, aiming to fully understand its nature, use it in future research, expand its path, and contribute to the progress of chemistry and medicine.
    Safety & Operational Standards
    About N- (1,3-benzodioxacyclopentene-5-ylmethyl) -4-fluorobenzenesulfonamide Product Safety and Operating Specifications
    V N- (1,3-benzodioxacyclopentene-5-ylmethyl) -4-fluorobenzenesulfonamide is an important substance in chemical research. During its experiment and production, safety and operating standards are of paramount importance.
    The first word is safety. This substance may have certain chemical activity and may come into contact with the skin and eyes, which may cause irritation. Therefore, when operating, it is necessary to wear suitable protective equipment, such as protective gloves, goggles, etc., to prevent accidental contact. And this product may be at risk of chemical reaction under specific conditions, so it needs to be stored in a cool, dry and well-ventilated place, away from fire and heat sources, and avoid mixing with strong oxidizing agents, strong acids, strong bases and other substances to prevent dangerous reactions.
    The following operating specifications. During the experimental operation, the relevant information should be read carefully to clarify its chemical properties and reaction characteristics. When taking it, be sure to take the equipment and method accurately to ensure accurate dosage. If the reaction process is involved, it is necessary to strictly control the reaction conditions, such as temperature, pressure, reaction time, etc., and operate cautiously according to the established process. After the reaction is completed, the treatment of the product should not be ignored lightly. It is necessary to follow the principles of environmental protection and safety, and properly dispose of waste to avoid pollution to the environment.
    In conclusion, in the research and application of N- (1,3-benzodioxacyclopentene-5-ylmethyl) -4-fluorobenzenesulfonamide, safety and operating standards are the cornerstones of ensuring personnel safety, smooth experimentation, and environmental friendliness, and must not be slack.
    Application Area
    Today there is a product called N- (1,3-benzodioxacyclopentene-5-ylmethyl) -4 -fluorobenzenesulfonamide. This compound has great potential in various application fields.
    In the field of medicine, it may be used to develop new agents for specific diseases, which are expected to show unique curative effects, help doctors heal diseases and solve people's pain. In the field of material research and development, it may be able to contribute to the creation of new materials, making the material specific and suitable for multiple scenarios.
    In the field of chemical production, this compound may be the key to optimizing the process and improving the product quality. However, the wonders of its application are yet to be explored in depth by our chemical researchers with a diligent heart and a state of study, so that we can make the best use of it, benefit the world, and make this compound bloom in various application fields.
    Research & Development
    Today there is a product called N- (1,3-benzodioxane-5-ylmethyl) -4-fluorobenzenesulfonamide. I am a chemical researcher and have been studying this product for a long time.
    Looking at its structure, it is unique and exquisite, and contains chemical wonders. In the process of research, its properties, such as the melting point of physical properties, solubility, and the reaction law of chemical activity, are carefully investigated.
    After repeated experiments, we have gained insight into its reaction mechanism under specific conditions, paving the way for development and application. It is expected that through unremitting research, it will be tapped into more potential, or used in drug research and development, or engaged in material innovation. We hope that with the efforts of our generation, we can promote this product from research to wide application, contribute to the development of the chemical field, and open a new chapter.
    Toxicity Research
    Study on the toxicity of * N * - (1,3-benzodioxyamyl-5-ylmethyl) -4-fluorobenzenesulfonamide
    Taste the properties of substances, beneficial and harmful, especially chemical substances. Today's study of * N * - (1,3-benzodioxyamyl-5-ylmethyl) -4-fluorobenzenesulfonamide This chemical, its toxicity is of great importance to us.
    Detailed observation of this product, the impact on living things is much unknown. Based on various experiments, observe its effect on living things. Or observe changes in cells, or depending on physiology. At first, animals were used as models and fed a certain amount of * N * - (1,3-benzodioxyamyl-5-ylmethyl) -4-fluorobenzenesulfonamide to observe their diet and behavior. Also check their organs to see if there is any damage.
    The study of toxicity is not timely. Different environments and doses can cause differences in toxicity. Only by careful investigation can we know the details, so as to avoid its harm, use it for its benefit, keep the well-being of all beings, and protect the tranquility of the environment.
    Future Prospects
    I try to study N- (3-Benzodioxol-5-Ylmethyl) -4-Fluorobenzenesulfonamide this thing, and feel that it has great prospects for future development. Its unique nature may be used in various new ways. In the field of medicine, it may be able to assist in the research of new drugs and cure serious diseases; in terms of materials, or introduce new materials, it has extraordinary properties. Although the current research is not complete, I am convinced that in time, I will be able to deeply understand its ability and expand its use. In the future, we should gather the wisdom of all, and make intensive research, so that this material can bloom its brilliance, be used by the world, and benefit people. It will become our scientific research ambition and add luster to the future development.
    Where to Buy N-(1,3-Benzodioxol-5-Ylmethyl)-4-Fluorobenzenesulfonamide in China?
    As a trusted N-(1,3-Benzodioxol-5-Ylmethyl)-4-Fluorobenzenesulfonamide manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading N-(1,3-Benzodioxol-5-Ylmethyl)-4-Fluorobenzenesulfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of N- (1,3-benzodioxane-5-ylmethyl) -4-fluorobenzenesulfonamide?
    The chemical structure of N- (1,3-naphthaleno-heterocyclopentene dioxide-5-methylphenyl) -4-bromonaphthaleno-phthalimide, let me explain in detail in this detailed text.
    This compound has a unique structure and contains several key structural fragments. First, the 1,3-naphthaleno-heterocyclopentene dioxide part, the naphthalene ring is a fused dicyclic aromatic hydrocarbon structure with a conjugated system, which endows the molecule with certain stability and special electronic properties. At the 1,3 position of this naphthalene ring, the heterocyclopentene dioxide structure is connected. This heterocyclic ring contains oxygen atoms, and the presence of heteroatoms affects the polarity and reactivity of the molecule.
    Furthermore, 5-methylphenyl is attached to the 5th position of naphthalene and heterocyclopentene dioxide. Methyl is a common alkyl group, which has a donor electron effect and can change the electron cloud density of the aromatic ring, which in turn affects the electron distribution and chemical activity of the whole molecule. The conjugation system of phenyl interacts with the naphthalene ring to enhance the degree of conjugation of the molecule, which has a significant impact on its optical and electrical properties.
    As for the part of 4-bromonaphthalene phthalimide, the naphthalene ring is connected to phthalimide. Phthalimide is a nitrogen-containing ring structure, and the lone pair electrons of the nitrogen atom participate in the conjugation, which affects the electron cloud distribution of the molecule. The bromine atom at the 4th position, due to its large electronegativity, is an electron-withdrawing group, which can adjust the polarity and reactivity of the molecule, and in organic synthesis, the bromine atom is often an important reaction check point, which can carry out a variety of substitution reactions, etc., providing the possibility for the derivatization of the compound.
    The overall structure of this compound, the interaction of various parts, endows it with unique physical and chemical properties and potential application value, and may have important uses in organic synthesis, materials science and other fields.
    What are the main uses of N- (1,3-benzodioxane-5-ylmethyl) -4-fluorobenzenesulfonamide?
    N- (1,3-benzodioxacyclopentene-5-ylmethyl) -4-bromobenzenesulfonamide has a wide range of uses. In the field of pharmaceutical research and development, it is often used as a key intermediate. Due to the unique structure of this compound, it can be combined with other active groups by organic synthesis, and then novel drugs with specific pharmacological activities can be created. For example, in the study of anti-tumor drugs, derivatives based on this have been found to inhibit proliferation in specific tumor cell lines, which may provide a new path for the development of anti-tumor drugs.
    In the field of materials science, N- (1,3-benzodioxacyclopentene-5-ylmethyl) -4-bromobenzenesulfonamide also has its uses. Because its structure contains groups such as benzene ring and sulfonamide group, it imparts specific electrical and optical properties to the material. For example, introducing it into polymer materials can improve the conductivity and photostability of materials, providing the possibility of preparing new photovoltaic materials, such as organic Light Emitting Diode (OLED), solar cells and other devices to improve their performance. In addition, in the field of organic synthetic chemistry, as an organic reagent with a unique structure, it can participate in many organic reactions, such as nucleophilic substitution reactions, coupling reactions, etc., providing a foundation for the construction of more complex and diverse organic molecular structures, enabling organic chemists to expand their compound libraries, explore new organic synthesis strategies and methods, and promote the development of organic synthetic chemistry.
    What are the physical properties of N- (1,3-benzodioxane-5-ylmethyl) -4-fluorobenzenesulfonamide?
    N- (1,3-benzodioxacyclopentene-5-ylmethyl) -4-bromobenzamide is an organic compound. This compound has specific physical properties, which are detailed as follows:
    Above the appearance properties, it may be solid under normal conditions, and it is mostly white to off-white crystalline powder. This form is convenient for storage and subsequent processing. In various chemical reactions and preparation processes, the powder form is conducive to dispersion and mixing, which can promote the reaction to be more uniform and efficient.
    In terms of melting point, its melting point is in a specific temperature range, but the exact value varies slightly due to differences in sample purity and test conditions. As a key physical property index, melting point is of great significance for the identification of compound purity. If the purity of the compound is high, the melting point range is usually narrow; conversely, the presence of impurities will cause the melting point to decrease and the melting range to widen.
    Solubility is also an important property. N- (1,3-benzodioxane-5-ylmethyl) -4-bromobenzamide exhibits different solubility properties in common organic solvents. Generally speaking, it has good solubility in halogenated hydrocarbon solvents such as dichloromethane and chloroform, and also has certain solubility in polar aprotic solvents such as acetonitrile and N, N-dimethylformamide (DMF). However, the solubility in water is relatively low. This solubility characteristic provides an important basis for the selection of reaction media in organic synthesis and subsequent separation and purification steps. For example, in the reaction stage, a suitable solvent can be selected according to the solubility of the reactant and the product to ensure the smooth progress of the reaction; when separating and purifying, its solubility difference can be used to obtain high-purity products by extraction, recrystallization and other means.
    In terms of stability, the compound is relatively stable under conventional storage conditions. However, it is necessary to avoid contact with strong oxidants, strong acids, strong bases and other substances, because some groups in the chemical structure may react with it, resulting in structural changes of the compound. At the same time, environmental factors such as light, high temperature, and high humidity may also affect its stability, so it should be stored in a cool, dry and dark place.
    What is the preparation method of N- (1,3-benzodioxane-5-ylmethyl) -4-fluorobenzenesulfonamide?
    To prepare N- (1,3-benzodioxane-5-methyl) -4-bromobenzamide, the method is as follows:
    First take 1,3-benzodioxane-5-formaldehyde, with a suitable reducing agent, such as sodium borohydride, in a suitable solvent, such as methanol, under low temperature and stirring conditions, reduce the aldehyde group to an alcoholic hydroxyl group to obtain 1,3-benzodioxane-5-methanol.
    Then this product is reacted with a suitable halogenating agent, such as phosphorus tribromide or hydrobromic acid, at a suitable temperature and reaction time, so that the alcoholic hydroxyl group is replaced by a bromine atom to obtain 1- (bromomethyl) -1,3-benzodioxane.
    Another 4-bromobenzoic acid is taken and reacted with dichlorosulfoxide under heated reflux to convert the carboxyl group into an acyl chloride to obtain 4-bromobenzoyl chloride.
    Subsequently, 1- (bromomethyl) -1,3-benzodioxane and 4-bromobenzoyl chloride are reacted with 4-bromobenzoyl chloride in a suitable organic solvent such as acetonitrile in the presence of a base, such as potassium carbonate, at a certain temperature and for a long time, so that the two substitution reactions occur to obtain N- (1,3-benzodioxane-5-methyl) -4-bromobenzoamide. After the reaction is completed, the product is purified by conventional separation and purification methods, such as column chromatography, etc., to obtain a relatively pure target product.
    What are the precautions for using N- (1,3-benzodioxane-5-ylmethyl) -4-fluorobenzenesulfonamide?
    N- (1,3-benzodioxacyclopentene-5-methyl) -4-chlorobenzamide during use, be sure to pay attention to the following things:
    First, safety protection is essential. This compound may be toxic and irritating, and when exposed, strict safety procedures should be followed. Those involved must wear appropriate protective equipment, such as gloves, goggles and protective clothing, to prevent skin, eyes and respiratory tract damage. In case of accidental contact, rinse with plenty of water immediately and seek medical consultation according to the actual situation.
    Second, precisely control the dosage. According to the specific application and reaction requirements, accurately weigh and strictly control the dosage of N- (1,3-benzodioxacyclopentene-5-methyl) -4-chlorobenzamide. Improper dosage may cause poor reaction effect, or cause side reactions, or even endanger experimental safety or product quality.
    Third, properly store the compound. Store it in a cool, dry and well-ventilated place, away from fire sources and oxidants. Some chemicals are not stable in specific environments, improper storage or cause them to deteriorate and decompose, which will affect the use efficiency and pose a safety hazard in serious cases.
    Fourth, the operating environment cannot be ignored. The use process should ensure smooth ventilation of the operating environment to avoid the accumulation of volatile gases from compounds. When necessary, use fume hoods and other equipment to ensure the air quality of the operating space and reduce the potential threat to the health of the operator.
    Fifth, follow the established operating procedures. Whether it is used for synthetic reactions or other purposes, it should be acted according to the established experimental procedures and operating procedures. Before operation, you need to be familiar with the relevant reaction mechanism and points to pay attention to, and do not change the operation steps without authorization to prevent accidents.