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Monofluorobenzene

Monofluorobenzene

Hongda Chemical

Specifications

HS Code

126348

Chemical Formula C6H5F
Molar Mass 96.102 g/mol
Appearance Colorless liquid
Odor Aromatic
Density 1.024 g/cm³ at 20 °C
Boiling Point 84.7 °C
Melting Point -44.7 °C
Solubility In Water Slightly soluble
Vapor Pressure 40 mmHg at 24.5 °C
Flash Point -12 °C
Refractive Index 1.4684 at 20 °C

As an accredited Monofluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing Monofluorobenzene packaged in 5 - liter containers for chemical use.
Storage Monofluorobenzene should be stored in a cool, well - ventilated area, away from heat sources and open flames. Keep it in a tightly - sealed container made of suitable materials like steel or certain plastics that can resist its corrosive effects. Store it separately from oxidizing agents and reactive chemicals to prevent potential chemical reactions.
Shipping Monofluorobenzene is shipped in tightly - sealed, corrosion - resistant containers. It's transported under regulated conditions to prevent spills and exposure, following strict hazardous chemical shipping guidelines due to its potentially harmful nature.
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Monofluorobenzene Monofluorobenzene
General Information
Historical Development
Monofluorobenzene is an organic compound. The study of its substances has gradually become apparent over the years. In the early years, the wise men worked hard in the field of organic chemistry and began to pay attention to this. At the beginning, the synthesis method was not good, and the yield was quite low. However, scholars were determined and unremitting exploration.
In later generations, science and technology advanced day by day, and new techniques emerged. Chemists used innovative methods to improve the synthesis of Monofluorobenzene, so that the yield and purity of Monofluorobenzene increased. Its application in industry has also become more and more extensive, either in the preparation of materials or in the synthesis of medicine.
Looking at its historical evolution, from the initial exploration of ignorance to the skillful application, it depends on the wisdom and perseverance of chemists. Therefore, Monofluorobenzene has gradually occupied an important position in the forest of chemistry and made great contributions to the rise of science and technology.
Product Overview
Today there is a substance called Monofluorobenzene. It is an organic compound composed of carbon, hydrogen, and fluorine elements. On the benzene ring, a hydrogen atom is replaced by a fluorine atom, so this shape is formed.
Looking at its properties, it is a colorless liquid at room temperature and has a special odor. Its boiling point and melting point are fixed, which can be measured according to physical methods. As for solubility, it is quite soluble in organic solvents, but slightly soluble in water.
This compound has a wide range of uses. In the field of organic synthesis, it is often an important raw material, and other compounds can be prepared through various reactions. In the pharmaceutical, pesticide, materials and other industries, it also has its uses, either to assist in drug research and development, or to enhance the efficiency of pesticides, or to modify materials.
There are various ways to prepare. It can be obtained by halogenation reaction, using benzene and fluorinated reagents. When preparing, it is necessary to pay attention to the reaction conditions, temperature, pressure, catalyst, etc., which are all related to the quality and quantity of the product.
Physical & Chemical Properties
Monofluorobenzene is an organic compound. Its physical properties, at room temperature, are colorless liquids with a slightly fragrant taste. Its boiling point is about 80 and 2 degrees Celsius, its melting point is negative 60 and 4 degrees Celsius, and its density is about 1.108 grams per cubic centimeter.
In terms of chemical properties, the presence of fluorine atoms on the benzene ring makes its reactivity different from that of benzene. It can participate in electrophilic substitution reactions, but due to the electron-withdrawing effect of fluorine atoms, the reaction rate is slightly slower than that of benzene. Under specific conditions, it can react with many reagents, such as interacting with metal magnesium, which can form Grignard reagents, and then be used to synthesize other organic compounds. All these physical and chemical properties are of great value in the field of organic synthesis.
Technical Specifications & Labeling
"Technical Specifications and Labeling (Commodity Parameters) for the Production of Monofluorobenzene"
The technical specifications for the production of monofluorobenzene (Monofluorobenzene) are of great significance. Take an appropriate amount of benzene and combine it with fluorine-containing reagents cleverly in a specific method. When reacting, control the temperature in an appropriate range and accurately control the duration. This is the key.
In terms of identification, for the container containing monofluorobenzene, the name "monofluorobenzene" must be declared, accompanied by a chemical formula, detailing the product parameters. Such as purity, it should reach a very high standard, and the impurity content must be strictly controlled. And remember its dangerous characteristics and show it to people with a conspicuous logo, so that those who touch it can know its nature and prevent problems before In this way, the combination of technical specifications and labels is accurate to become a good product.
Preparation Method
The method of making monofluorobenzene is related to the raw materials and production process, reaction steps and catalytic mechanism. The raw materials are commonly used benzene and fluoride. First, benzene and specific fluoride are mixed in a suitable container, and this is the starting point. The reaction step needs to be carefully controlled at temperature, usually at a moderate high temperature, about hundreds of degrees Celsius. By using the effect of a catalyst to accelerate the reaction process, metal halides are often selected as catalysts to reduce the activation energy of the reaction. In this process, the hydrogen atoms on the benzene ring are gradually replaced by fluorine atoms, and finally monofluorobenzene is obtained. And during the preparation, all aspects need to be precisely controlled, from the ratio of raw materials to the reaction time, all affect the purity and yield of the product, so that high-quality monofluorobenzene products
Chemical Reactions & Modifications
I dedicated myself to the chemical research of Monofluorobenzene to explore its reaction and modification. The reaction of this substance is quite unique, and its chemical changes are often unexpected. In the past, the method of modifying Monofluorobenzene encountered many obstacles, and the results were unsatisfactory.
After repeated research, the structure of Monofluorobenzene was observed, and the opportunity for reaction was explored. Changing the reaction conditions, such as temperature and pressure, and adding a special catalyst, actually changed the reaction path. In this way, the modification of Monofluorobenzene has achieved remarkable results, and the quality and quantity of the product have been improved.
This research is not only about Monofluorobenzene, but also an exploration in the field of chemistry. Make us understand that although the reaction of matter is common sense, subtle changes may lead to significant changes. I hope this discovery will help in the progress of future chemical processes.
Synonyms & Product Names
Today there is a product called Monofluorobenzene. Its synonymous name is also known as fluorobenzene. This product is widely used in the field of chemical industry.
Fluorobenzene has a clear color and a specific taste, is stable and flexible in reaction. In the organic synthesis industry, it is often a key raw material. Or to help form exquisite drugs, or to participate in the manufacture of high-tech materials, its power should not be underestimated.
The name of its product also has different names in the market. However, its essence is the same thing. Chemical companies often use it under the name of different products according to their characteristics and uses. In the process of research and development, we should study its synonymous name and trade name in detail to clarify its nature and make good use of it in order to make the chemical industry flourish.
Safety & Operational Standards
"Monofluorobenzene Safety Production and Operation Code"
There is Monofluorobenzene today, which is related to the safety of production and operation standards, and must not be ignored.
Monofluorobenzene is unique. When operating, it is first necessary to understand its physical and chemical properties. It is flammable and toxic to a certain extent, so fireworks are strictly prohibited in the place to prevent unexpected fires. The operation room should be well ventilated to drive away the toxic gas and ensure the well-being of the operator.
Those who work must wear professional protective equipment. Protective clothing, gloves, and masks are readily available, and they must not be slack. This is to protect them from Monofluorobenzene. When handling, the action should be slow and steady to avoid its dumping, collision, and leakage.
In case of leakage, do not panic. Quickly close the relevant valves and cut off their sources. When there is a small leak, it can be adsorbed by inert substances such as sand and vermiculite, and it can be properly collected and disposed of. If there is a large leak, everyone needs to be evacuated immediately, and warning labels should be set up. Report it to the relevant department and dispose of it according to professional methods.
There are also regulations for storage. It is suitable for a cool and ventilated warehouse, away from fire and heat sources. It should be stored separately from oxidants and edible chemicals, and must not be mixed to avoid chemical reactions, which can lead to disaster. The temperature and humidity in the warehouse should be controlled to an appropriate degree, and special personnel should be set up to inspect regularly. If there is any abnormality, it will be dealt with quickly.
The safe production and operation of Monofluorobenzene requires everyone to be cautious. Follow this specification to ensure the smooth production and the safety of personnel.
Application Area
Today, there is a thing called Monofluorobenzene, which is widely used. In the field of medicine, it can be the foundation for making good medicines, helping to treat various diseases, and saving people from diseases and pains. In the chemical industry, it can be used as raw materials to make all kinds of fine things and increase the prosperity of industry. In the process of scientific research, it is essential to explore new principles and innovative methods, opening the door of wisdom and leading the direction of exploration. In the production of spices, it can also add a unique fragrance, pleasing people's sense of smell. Monofluorobenzene has extraordinary power in various application fields. If it can be used well, it will be able to contribute to the development of the world, adding bricks and tiles, improving advantages and eliminating disadvantages, and benefiting people.
Research & Development
I am committed to the research of Monofluorobenzene. This compound has unique properties and wide application, and has potential in many fields. At the beginning, I explored its synthesis method, tried many times, and experienced twists and turns. All raw materials and conditions are carefully considered to find the best path. After long-term research, gains have been made, and the efficiency and purity of synthesis have been improved.
Then, looking at its application and expansion, in the field of medicine, it is expected to help the development of new drugs, or improve the effectiveness of disease treatment; in terms of materials, it may be able to optimize the properties of materials to make them more tough and durable. We continue to explore and strive to explore more possibilities. Although the road ahead is long, adhering to the heart of research will surely promote Monofluorobenzene from research to wider application, promote its continuous development, and bring benefits to the world.
Toxicity Research
The industry of chemical industry is related to people's livelihood, but the study of poisons in it should not be careless. Today, in the case of Monofluorobenzene, the study of its toxicity is of paramount importance.
Monofluorobenzene has a clear color and a different taste, and is widely used in various fields of chemical industry. However, its sex is strong and toxic. Those who have tried it, took white mice as an experiment, and fed them food containing this thing. Not long after, the white mice were hyperactive and restless, eating less and less, and their bodies became weaker. It was also observed that their organs, liver and spleen had abnormal changes, uneven color and texture.
And if this thing is scattered in the atmosphere, people will inhale it, injure the lung meridians, cause cough and asthma, and damage the internal organs for a long time. If it flows in the water, all aquatic things will suffer from it, fish and shrimp will die, and algae will wither. Therefore, studying its toxicity, understanding its harm, and making preventive measures can ensure people's well-being, ecological peace, and the chemical industry can also prosper for a long time.
Future Prospects
Looking at today's world, science and technology are changing day by day. In the field of chemical industry, Monofluorobenzene also has an extraordinary future prospect. Its unique nature and wide range of uses.
In the future, one of them may shine in the creation of medicine. With its characteristics, it can be the cornerstone of the research and development of new drugs, helping doctors overcome more diseases and protecting the health of all beings. Second, the electronics industry may also rely on it. As electronic products become more and more sophisticated, they may emerge in circuit materials and other aspects, making devices more efficient and stable.
Furthermore, in the field of materials science, or with the power of Monofluorobenzene, develop new functional materials. Such as high-performance polymers, used in aerospace, automotive and other industries to improve device performance and open up new horizons. All of this shows that Monofluorobenzene has broad future prospects and is expected to bring revolutionary changes to various fields, creating infinite possibilities.
Where to Buy Monofluorobenzene in China?
As a trusted Monofluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading Monofluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of monofluorobenzene?
Monofluorobenzene has a wide range of uses. In the field of organic synthesis, it is often a key raw material. The unique properties of fluorine atoms on the benzene ring can make chemical reactions take a different direction.
In terms of pharmaceutical synthesis, monofluorobenzene can be used as an intermediate to prepare a variety of drugs. Its structure can endow drugs with specific biological activities and pharmacological properties. For example, some drugs with antibacterial and antiviral effects have monofluorobenzene in their synthesis pathways. Its participation in reactions may optimize the structure of drug molecules, enhance the ability of drugs to bind to targets, and improve drug efficacy.
In the field of materials science, monofluorobenzene also has important uses. In the preparation of high-performance polymer materials, monomers containing monofluorobenzene structures can be introduced to improve the properties of the polymer. Such as improving the thermal stability, chemical stability and mechanical properties of the material. This is because the high electronegativity of fluorine atoms can enhance the interaction between molecules, thereby improving the overall properties of the material.
In addition, in the field of pesticide synthesis, monofluorobenzene also plays an important role. The pesticides it participates in the synthesis may have the characteristics of high efficiency and low toxicity. Due to the existence of fluorine atoms, it can affect the way pesticide molecules interact with targets in pests, enhance the killing effect of pesticides on pests, and reduce the harm to the environment and non-target organisms.
Monofluorobenzene is an indispensable and important substance in many fields such as organic synthesis, medicine, materials and pesticides. With its unique structure and properties, it provides assistance for the development of various fields.
What are the physical properties of monofluorobenzene?
Monofluorobenzene (Monofluorobenzene) is one of the organic compounds. Its physical properties are unique, let me tell you one by one.
Monofluorobenzene is a colorless and transparent liquid under normal temperature and pressure, and it looks clear, like water in a mirror. Its smell is special and slightly aromatic, but it should not be smelled lightly to prevent harm to the body.
As for its boiling point, it is about 80 degrees, and to be precise, it is between 85 and 87 degrees Celsius. The characteristics of this boiling point allow it to be converted from liquid to gas when heated moderately. The freezing point is relatively low, about -44 degrees Celsius, which means that it will condense into a solid state at lower temperatures.
The density of monofluorobenzene is smaller than that of water, about 1.024g/cm ³. If it is co-located with water, monofluorobenzene will float on water, just like oil floats on water.
Furthermore, monofluorobenzene is slightly soluble in water, which is similar to many organic compounds. However, it can be miscible with organic solvents such as ethanol and ether, just like water emulsion, and can be mixed evenly.
The vapor pressure of monofluorobenzene also has its value at a specific temperature, which is related to the difficulty of evaporation. The relative density of its vapor is greater than that of air. If it leaks in the air, the vapor will spread close to the ground, which also needs to be prevented.
In addition, the refractive index of monofluorobenzene is also an important physical property, about 1.468 to 1.470, which reflects its refractive properties of light and may have important uses in optics and related research.
What are the chemical properties of monofluorobenzene?
Monofluorobenzene has unique chemical properties and is related to many fields of organic chemistry, which is quite important to chemists.
Monofluorobenzene has the commonality of aromatic hydrocarbons, and its benzene ring structure endows it with certain stability. In the electrophilic substitution reaction, although fluorine atoms have electron-absorbing induction effect, the electron cloud density distribution of the benzene ring varies because it can borrow p-π conjugation effect power supply. For example, in the halogenation reaction, monofluorobenzene is more inclined to ortho and para-substitution than benzene, which is due to the slightly higher electron cloud density of fluorine atoms.
Its stability is also reflected in the thermal stability, which is more stable than some organic compounds containing active groups. It can withstand higher temperatures without easy decomposition, and has its advantages in high temperature reaction environments.
In terms of polarity, fluorine atoms have large electronegativity, causing monofluorobenzene to have a certain polarity, which affects its solubility. In organic solvents, monofluorobenzene exhibits different solubility properties from non-polar benzene, and can be miscible with some solvents with moderate polarity. This property is of great significance in separation, purification and reaction medium selection.
And monofluorobenzene can participate in a variety of organic synthesis reactions and is an important organic synthesis intermediate. If reacted with nucleophiles, fluorine atoms can be replaced to derive various fluorine-containing organic compounds, which are widely used in medicine, pesticides, materials and other fields.
Monofluorobenzene is rich in chemical properties and has important application value in many fields such as organic synthesis and materials science. It is a key object of organic chemistry research.
What are the production methods of monofluorobenzene?
For monofluorobenzene, there are three methods for preparation.
One is the halogen exchange method. The aryl diazonium salt interacts with fluoroboronic acid to obtain aryl fluoroboronic acid, which is decomposed by heating to obtain monofluorobenzene. This is a classic method, the diazonium salt is easy to prepare, and the reaction conditions are mild. If aniline is used as the starting point, it is diazotized to form a salt with fluoroboronic acid, and pyrolysis can be obtained. However, the steps are slightly complicated, and careful operation is required to avoid the danger of diazonium salts.
The second is the direct fluorination method. Benzene is used as the substrate, and a moderately active fluorinating agent, such as Selectfluor, is used. Such fluorinating agents are selective and can introduce fluorine atoms into the benzene ring. The reaction is often The advantages are simple steps, high atomic economy, expensive fluorinating agent, and the need to fine-tune the reaction conditions to prevent the formation of polyfluorides.
The third is electrochemical fluorination. In a specific electrolytic cell, benzene is used as raw material, and fluoridation is achieved through an electrochemical process in a fluorine-containing electrolyte solution. This is an emerging method with mild conditions, environmental friendliness, and can precisely control the reaction process. However, the equipment requirements are high, and professional electrochemical knowledge and technology are required. Industrialization will take time.
These three methods have their own advantages and disadvantages. The halogen exchange method is classic and reliable, the direct fluorination method is simple and efficient, and the electrochemical fluorination method has potential. In actual preparation, the choice is based on factors such as raw material availability, cost, and product purity.
What are the precautions for monofluorobenzene during storage and transportation?
Monofluorobenzene (Monofluorobenzene) is an organic compound. During storage and transportation, many things should be paid attention to.
First safety protection. Monofluorobenzene is toxic and irritating, touching the human body, or causing skin and eye damage. If inhaled or eaten by mistake, it is more dangerous to health. Therefore, when operating, appropriate protective equipment must be worn, such as protective clothing, gloves, goggles and gas masks, to ensure the safety of operators.
The second is the storage environment. It should be placed in a cool and well-ventilated place, away from fire and heat sources. Because it is a flammable liquid, it can cause combustion and explosion in case of open flames and hot topics. The temperature of the storage place should be controlled within an appropriate range, and should be stored separately from oxidants, acids, alkalis, etc., and should not be mixed to prevent chemical reactions.
Furthermore, the transportation process cannot be ignored. The transportation vehicle must comply with the relevant regulations on the transportation of hazardous chemicals, and have corresponding safety facilities and emergency treatment equipment. During transportation, it is necessary to ensure that the container does not leak, collapse, fall or damage. Driving should be stable, avoid sudden braking and sharp turns to prevent accidents. At the same time, transportation personnel also need professional training, familiar with the characteristics of monofluorobenzene and emergency treatment methods.
In short, the storage and transportation of monofluorobenzene is related to personnel safety and environmental safety, and all aspects should be strictly adhered to, operated with caution, and must not be slack.