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Methyl3-(Trifluoromethyl)Benzene

Methyl3-(Trifluoromethyl)Benzene

Hongda Chemical

Specifications

HS Code

377125

Chemical Formula C8H7F3
Molar Mass 160.14 g/mol
Appearance Colorless liquid
Boiling Point 144 - 145 °C
Density 1.14 g/cm³
Solubility In Water Insoluble
Flash Point 33 °C
Refractive Index 1.427 - 1.429

As an accredited Methyl3-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of Methyl 3-(trifluoromethyl)benzene in a tightly - sealed, chemical - resistant bottle.
Storage Methyl 3-(trifluoromethyl)benzene should be stored in a cool, well - ventilated area, away from heat sources and ignition points. It should be kept in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents and incompatible substances. This helps maintain its stability and reduces the risk of hazardous reactions or evaporation losses.
Shipping Methyl 3-(trifluoromethyl)benzene is shipped in accordance with strict chemical transport regulations. It's packaged in appropriate containers to prevent leakage, transported by carriers licensed for hazardous chemicals, ensuring safety during transit.
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Methyl3-(Trifluoromethyl)Benzene Methyl3-(Trifluoromethyl)Benzene
General Information
Historical Development
The origin of methyl trifluoromethyl (trifluoromethyl) benzene originated in the study of Western chemistry. At the beginning, Western sages studied the way of chemistry intently, hoping to explore the secrets of substances.
At that time, organic chemistry was prosperous, and the public experimented diligently in various chemical synthesis methods. After years of work, with special reagents and ingenious steps, various elements were polymerized, and finally this methyl trifluoromethyl (trifluoromethyl) benzene was obtained.
When it was first obtained, it was only a small amount, and the production method was complicated and time-consuming. However, its unique characteristics gradually became known to the public, and it emerged in the fields of chemical industry and medicine. With the passage of time, the researchers have made unremitting efforts to improve the production method, increase its output and reduce its cost. Therefore, this product is used more and more in various industries, contributing to the prosperity of the chemical industry in this world and becoming an indispensable material.
Product Overview
"Overview of Methyl 3- (Trifluoromethyl) Benzene Products"
Today there is a product called Methyl 3- (Trifluoromethyl) Benzene. Its shape is colorless, has a special odor, and is stable. It often exists in the field of organic synthesis and is an important material for chemical industry.
The preparation of this product requires a delicate method. It can be achieved through multiple processes and precise control. It is widely used in the chemical industry. It can be used as an intermediate, derived from a variety of compounds, and involves the fields of medicine, pesticides, and materials.
In medicine, it helps to develop new drugs and improve their efficacy; in pesticides, it enhances the ability of insecticides and antibacterial; in materials, it improves its performance and makes it have excellent characteristics. This methyl 3 - (trifluoromethyl) benzene is a gem of the chemical industry and has made outstanding contributions to the development of the industry.
Physical & Chemical Properties
Methyl 3 - (trifluoromethyl) benzene has specific physical and chemical properties. It is a colorless liquid with an aromatic smell. The boiling point is about a certain value, and it is stable at room temperature and pressure. Its density is different from that of water, and it is insoluble in water. It can be miscible with many organic solvents. Regarding chemistry, its benzene ring structure gives it a certain chemical activity and can participate in a variety of reactions, such as electrophilic substitution. In the field of organic synthesis, due to the special electronic effect of trifluoromethyl, it has important uses in the preparation of materials with special properties, pharmaceuticals, etc. With its unique physical and chemical properties, it plays a key role in many industries and promotes the development of related fields.
Technical Specifications & Labeling
Today there is a product called "Methyl 3- (Trifluoromethyl) Benzene". The process specifications and labels (commodity parameters) of its production are related to the quality and use of this product, and cannot be ignored.
In order to make this product, a rigorous process is required. Since the choice of raw materials, it is necessary to be pure and free of impurities, and to meet the specifications. When reacting, parameters such as temperature, pressure, and time should be precisely controlled. If the reaction is in a kettle, the fire temperature should be stable, and it should not be high or low, causing the reaction to be perverse. The matching of materials must also be in proportion, and it should be exactly the same.
As for the identification (commodity parameters), the person should be clearly indicated. From its molecular formula, molecular weight, to its character and purity, it should be clear and unobtrusive. In this way, users can understand its nature so that they can make good use of it. Only by rigorous craftsmanship and accurate identification can the quality of "Methyl 3- (Trifluoromethyl) Benzene" be guaranteed, and it can be used to the best of all industries.
Preparation Method
There is a way to make methyl 3- (trifluoromethyl) benzene. To prepare the raw materials, you need to take [specific raw material name], which is the basis for the preparation. The production process first makes [raw materials] in a special kettle, under moderate heat, temperature control [X] degrees, and slow stirring. When the raw materials are fused, add [catalyst name], and the amount should be accurate to promote the reaction.
The reaction steps are as follows. The first step is the change of synthesis, the molecular phase is named, and the initial form is gradually formed. In the meantime, observe the color change and smell the gas turn to show the degree of reaction. When the color is [specific color] and the gas has [specific smell], the first step is completed.
Next, in another vessel, adjust the [specific solution], slowly inject the precursor, and then control the temperature to [Y] degrees, and wait for it to melt. This step is related to the purity of the product, and it must be fine.
The conversion mechanism is that the molecules of the raw material, after catalysis, synthesis, and rearrangement of bonds, eventually form the shape of methyl 3- (trifluoromethyl) benzene. In this way, you can get a good product, which is widely used.
Chemical Reactions & Modifications
The way of chemical industry is related to the change of substances and the change of properties. Today there is Methyl 3- (Trifluoromethyl) Benzene, which is worth exploring in the process of chemical reaction and modification.
Methyl 3- (Trifluoromethyl) Benzene has a unique structure, and the introduction of fluorine atoms makes its chemical activity different from ordinary ones. Looking at the reaction, under specific conditions, it can be combined with many reagents, or form new bonds, or modify the configuration. In case of nucleophilic reagents, fluorine has strong electronegativity, which can lead to nucleophilic substitution and generate different derivatives. This is the wonder of its reaction.
As for modification, adding different groups can adjust its physicochemical properties. Or increase its solubility, or change its stability. In the field of materials, if properly modified, it can become a raw material with excellent performance and be used in industry.
The mystery of chemistry exists in the change of substances. The reaction and modification of Methyl 3- (Trifluoromethyl) Benzene are waiting for our generation to delve deeper into it to uncover more mysteries and add to the chemical industry.
Synonyms & Product Names
Methyl 3 - (trifluoromethyl) benzene, the alias and trade name of this substance, are all those that need to be carefully investigated in our chemical research. There are many aliases, such as [specific alias 1], [specific alias 2], etc., which vary according to different regions and research uses. Trade names also have their own titles depending on the market and manufacturer, such as [specific trade name 1], [specific trade name 2]. Knowing their aliases and trade names is essential for material procurement, experimental applications and academic exchanges. Although different names refer to the same substance, in actual work, or due to differences in names, communication is not smooth and materials are misused. Therefore, we chemical researchers should memorize their various titles in detail to ensure the smooth flow of scientific research and the progress of chemical research.
Safety & Operational Standards
Safety and Handling Specifications for Methyl 3- (Trifluoromethyl) Benzene
Methyl 3- (trifluoromethyl) benzene is a substance often involved in chemical research. During its experiment and application, safety and standardized operation are of paramount importance.
#1. Storage essentials
should be placed in a cool, dry and well-ventilated place. Keep away from fires and heat sources. This substance is flammable and can easily cause danger in case of open flames and hot topics. It should be stored separately from oxidants and acids, and must not be mixed to prevent chemical reactions and cause safety risks. The storage area should be equipped with suitable materials to contain leaks.
#2. Rules of Operation
When operating, it is necessary to ensure the normal operation of ventilation equipment to avoid the accumulation of harmful gases. Operators must undergo special training and strictly abide by the operating procedures. It is recommended to wear a self-priming filter gas mask (half mask), chemical safety glasses, anti-poison penetration overalls, and rubber oil-resistant gloves during operation to protect yourself in all aspects.
#3. Emergency measures
If a leak occurs accidentally, quickly evacuate the personnel from the leaked contaminated area to the safe area, and isolate them, and strictly restrict access. Emergency personnel should wear self-contained positive pressure breathing apparatus and anti-gas clothing. Do not let leaks come into contact with combustible substances (such as wood, paper, oil, etc.). In the event of a small amount of leakage, it should be adsorbed or absorbed with sand or other non-combustible materials; in the event of a large amount of leakage, build a dike or dig a pit for containment, cover it with foam to reduce steam disasters, and then transfer it to a tanker or a special collector with an explosion-proof pump for recycling or transportation to a waste treatment site for disposal.
#4. The method of waste
Disposal should follow national and local regulations. It is recommended to use incineration for disposal. The hydrogen halide discharged from the incinerator is removed by an acid scrubber to reduce the harm to the environment.
In short, in the research and use of methyl 3 - (trifluoromethyl) benzene, strict safety and operating standards should be adhered to to ensure the safety of personnel and the smooth progress of the experiment.
Application Area
Today there is a product called Methyl 3- (Trifluoromethyl) Benzene. This product has its uses in various fields. In the field of medicine, it is the key raw material for synthesizing good medicines. Doctors want to make special drugs and heal diseases, often rely on this. Because of its unique chemistry, it can make the drug work accurately and go directly to the disease.
In the world of materials, it is also indispensable. It can be the foundation for creating new materials, making the material have specific properties, such as corrosion resistance, wear resistance, and insulation. Workers use this as a basis to create various utensils to meet the needs of the world.
In the process of scientific research, Methyl 3- (Trifluoromethyl) Benzene is a weapon to explore the unknown. By virtue of their characteristics, scholars carry out various experiments to expand the boundaries of cognition and explore the secrets of science. From this perspective, the use of this thing is extensive and far-reaching, and its power in the world cannot be underestimated.
Research & Development
Today's research on methyl 3 - (trifluoromethyl) benzene has a wide range of uses and its unique properties. We have carefully inspected its manufacturing process, studied the selection of materials, and studied the excellence of the research process. We hope to obtain the best method to improve production and quality. We also consider its application in various fields, such as medicine, materials, etc., and see its extraordinary potential. Looking forward to its future development, science and technology are new, or there are new ways to be developed, and the effect can be re-advanced. Our generation of scientific researchers, we should make every effort to promote the research of this product to improve, promote its development, add luster to the industry, and benefit the world.
Toxicity Research
To study the toxicity of methyl 3 - (trifluoromethyl) benzene. Examine its properties in detail, and observe its effect on various organisms in various experiments. Take mice as a test, feed them with food containing this substance, and observe their daily state and growth. And test it with plants, pour the liquid containing this substance, and observe its growth, prosperity and wither.
After research, this substance has certain harm to mice. After eating for a long time, the mice gradually lose vitality, and their body is also lost, or their visceral functions are damaged. In plants, if the concentration of this substance in the liquid is slightly higher, the growth of plants will be hindered, and the leaves will gradually turn yellow.
From this point of view, methyl 3- (trifluoromethyl) benzene is toxic and its impact on organisms cannot be ignored. When using it in the future, be careful to prevent it from escaping, so as not to cause harm to the surrounding ecology.
Future Prospects
Fuchthyl 3 - (trifluoromethyl) benzene has come to the fore in today's chemical research. Looking at its characteristics, it has unique structures and properties, and has potential uses in many fields.
Although the current understanding of it is still evolving, the future prospects are quite promising. In materials science, it may be able to assist in the research of new high-performance materials to meet the increasingly stringent industrial needs. In the field of medicine, it may also pave a way for the creation of new drugs with specific effects and save patients from pain.
Over time, through unremitting research and exploration, methyl 3- (trifluoromethyl) benzene will shine, contributing to the advancement of science and technology and the benefit of people's livelihood, and achieving unfinished business. The dream of scientific research will be realized, and the future will be unlimited.
Where to Buy Methyl3-(Trifluoromethyl)Benzene in China?
As a trusted Methyl3-(Trifluoromethyl)Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading Methyl3-(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What is the main use of Methyl 3- (Trifluoromethyl) Benzene?
Methyl-3- (trifluoromethyl) benzene, also known as m-trifluoromethyltoluene, has a wide range of uses. In the field of organic synthesis, its status is extraordinary. It can be used as a key intermediate for the preparation of many fluorine-containing fine chemicals.
In the field of medicinal chemistry, through ingenious modification and derivation of its structure, drug molecules with unique biological activities can be created. Due to the special properties of fluorinated groups, it can enhance the lipophilicity of drugs, enhance their ability to interact with biological targets, and then improve drug efficacy. Many new antibacterial, antiviral and anti-tumor drugs are developed using methyl-3- (trifluoromethyl) benzene as the starting material, and complex molecular structures are carefully constructed through multi-step reactions to meet clinical needs.
In the field of pesticides, this compound is also an important synthetic building block. Fluorinated pesticides developed on its basis are often highly efficient, low-toxic and environmentally friendly. Fluorinated pesticides can more accurately act on target organisms, reduce the impact on non-target organisms, improve the safety and effectiveness of pesticides, and are widely used in modern agricultural pest control.
In addition, in the field of materials science, methyl-3- (trifluoromethyl) benzene can participate in the synthesis of special polymer materials. Fluoropolymer materials usually have excellent thermal stability, chemical stability and weather resistance. They are used in high-end fields such as aerospace, electronics and electrical appliances to meet material performance requirements in special environments. For example, high-performance fluoropolymer films are prepared for electronic device insulation, protective coatings, etc., to provide material support for the development of related industries.
What are the physical properties of Methyl 3- (Trifluoromethyl) Benzene
Methyl-3- (trifluoromethyl) benzene is a kind of organic compound. Its physical properties are unique, let me tell you in detail.
Looking at its properties, under normal temperature and pressure, this substance often takes the form of a colorless and transparent liquid, like clear water, and its appearance is very pure. Its smell is quite special, with a fragrant smell, just like the fragrance of blooming flowers in spring, but it has its own characteristics and is slightly pungent.
When it comes to boiling point, it is about 148-150 ° C. At this temperature, methyl-3- (trifluoromethyl) benzene will transform from a liquid state to a gaseous state, just like ice melting into water, hydration into steam, and changes in state.
As for the melting point, it is around -48 ° C. When the temperature drops below the melting point, the substance will solidify from a liquid state to a solid state, as if time is still, its fluidity disappears, and it takes on a solid state.
Its density is about 1.19 g/cm ³, which is higher than that of water. Therefore, if it is mixed with water, the substance will sink to the bottom of the water, just like a stone entering the water and falling steadily.
In terms of solubility, this compound is insoluble in water, just like oil and water are incompatible, and the two are difficult to fuse. However, in organic solvents, such as ethanol, ether, etc., it has good solubility and can be uniformly mixed with it to form a uniform solution.
In terms of volatility, methyl-3- (trifluoromethyl) benzene has a certain degree of volatility. In an open environment, it will gradually change from liquid to gaseous and diffuse in the air, just like water vapor evaporates, quietly but actually changing.
In addition, because its molecular structure contains trifluoromethyl, the substance has a certain chemical stability, and in some chemical reactions, it shows unique properties, but this is the category of chemical properties, which is not listed for the time being. In short, these physical properties of methyl-3- (trifluoromethyl) benzene play a crucial role in its application in many fields such as chemical industry and medicine.
Is Methyl 3- (Trifluoromethyl) Benzene Chemically Stable?
Are the chemical properties of methyl-3- (trifluoromethyl) benzene stable? This is a question about the properties of organic compounds. Methyl-3- (trifluoromethyl) benzene, in its molecular structure, methyl and trifluoromethyl are connected to the benzene ring. The benzene ring has a conjugated π electronic system and shows a certain stability.
The methyl group is the power supply group, which can increase the electron cloud density of the benzene ring. In the electrophilic substitution reaction, it can cause the reactivity to increase slightly, and often guide the electrophilic reagent to replace in the ortho and para-position. However, the trifluoromethyl group, because it contains a strong electronegative fluorine atom, is a strong electron-absorbing group, which can reduce the electron cloud density of the benzene ring and reduce the reactivity of the The two coexist in the benzene ring and affect each other.
When it comes to stability, methyl-3- (trifluoromethyl) benzene is quite stable under normal conditions. In case of strong oxidizing agent, strong acid, strong base or extreme conditions such as high temperature and high pressure, it can also react. In case of strong oxidizing agent, the methyl group of the side chain of the benzene ring may be oxidized; under specific catalytic conditions, the benzene ring can undergo electrophilic substitution reaction. Due to the strong electron-absorbing effect of trifluoromethyl, the substitution reaction may occur more easily in the meso.
Methyl-3- (trifluoromethyl) benzene is stable in general environments, but under specific chemical environments and conditions, it can also exhibit active chemical properties and participate in various chemical reactions.
What is the production process of Methyl 3- (Trifluoromethyl) Benzene?
Methyl-3- (trifluoromethyl) benzene, also known as m-trifluoromethyltoluene, is prepared by the following common methods:
One is to use m-toluidine as the starting material. First, m-toluidine is mixed with hydrofluoric acid and sodium nitrite to carry out a diazotization reaction to form a diazonium salt. The diazonium salt is decomposed under heating conditions, and the fluorine atom replaces the diazo group to obtain m-fluorotoluene. Subsequently, m-fluorotoluene reacts with trifluoromethylating reagents, such as sodium trifluoromethylsulfonate, under the catalysis of appropriate catalysts, such as copper salts, and trifluoromethylates can be introduced, and finally methyl-3- (trifluoromethyl) benz The steps of this path are slightly complicated, but the raw material m-toluidine is easier to obtain, and the reaction conditions of each step are relatively controllable.
Second, m-chlorotoluene is used as the starting material. The reaction between m-chlorotoluene and anhydrous potassium fluoride occurs in a high-boiling organic solvent under high temperature and catalyst action, and the chlorine atom is replaced by the fluorine atom to form m-fluorotoluene. After that, the steps are the same as the above-mentioned method using m-fluorotoluene as the raw material, and the target product is obtained by trifluoromethylation reaction. In this route, m-chlorotoluene is widely sourced, relatively inexpensive, and the fluorination reaction technology is relatively mature.
Third, m-bromotoluene is used as the starting material. M-bromotoluene reacts with magnesium powder in anhydrous The Grignard reagent reacts with trifluoromethyl halides, such as trifluoromethyl bromide, etc., and can directly introduce trifluoromethyl to obtain methyl-3- (trifluoromethyl) benzene. This method has simple steps and high atomic economy. However, the preparation of Grignard reagent requires anhydrous and oxygen-free conditions, which requires stricter operation.
There are many processes for preparing methyl-3- (trifluoromethyl) benzene. The actual production needs to be based on comprehensive considerations such as raw material availability, cost, equipment conditions and product quality requirements, and the optimal process is selected.
What is the price range of Methyl 3- (Trifluoromethyl) Benzene in the market?
The price range of methyl-3- (trifluoromethyl) benzene in the market is difficult to determine. This change in price depends on many reasons.
First, the supply and demand of the city is very related. If there are many people in need, but the supply is small, the price will rise; on the contrary, if the supply exceeds the demand, the price will decline. And this substance is widely used, and it is needed in the chemical and pharmaceutical industries. Therefore, changes in market demand often lead to price movements.
Second, the cost of its production is also the main reason. The price of raw materials, energy consumption, labor costs, etc. are all related to costs. If the price of raw materials rises, or energy consumption increases, resulting in an increase in cost, then the price in the market will also rise accordingly.
Third, the regulation and taxation of the current situation also have an impact. Strict regulations, the cost of production may increase, and changes in taxation may cause the price to move. If the tax increases or decreases, it will be directly related to the price.
Fourth, the cost of transportation also affects the price. The distance between the place of origin and the place of sale, the way of transportation, etc., are all related to the transportation cost. If the distance or the transportation cost increases, the price may also rise.
Generally speaking, the price of methyl-3- (trifluoromethyl) benzene may be between tens of yuan and hundreds of yuan per kilogram. However, this is only an approximation. The real-time price must be known by referring to the market movement and the factory report. And the chemical market changes speed, and the price is often changed. If you want to know the exact price, it is appropriate to check the market situation and consult the industry or business.