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M-Fluoroiodobenzene

M-Fluoroiodobenzene

Hongda Chemical

Specifications

HS Code

340694

Chemical Formula C6H4FI
Molecular Weight 188.00
Appearance Colorless to light yellow liquid
Boiling Point 178 - 180 °C
Melting Point N/A
Density 1.809 g/cm³
Flash Point 68 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Vapor Pressure N/A
Stability Stable under normal conditions

As an accredited M-Fluoroiodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of M - fluoroiodobenzene packaged in a sealed, chemical - resistant bottle.
Storage M - fluoroiodobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. It should be kept in a tightly - sealed container, preferably made of corrosion - resistant materials like glass or specific plastics. Avoid storing it near oxidizing agents or substances that could react with it, as M - fluoroiodobenzene is potentially reactive.
Shipping M - fluoroiodobenzene is shipped in specialized, well - sealed containers. These are designed to prevent leakage due to its chemical nature. Shipment follows strict hazardous material regulations, ensuring safe transport to the destination.
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M-Fluoroiodobenzene M-Fluoroiodobenzene
General Information
Historical Development
M-Fluoroiodobenzene is also an organic compound. The history of its development, at the beginning, chemists devoted themselves to the field of organic synthesis, hoping to expand the category of compounds. At the beginning, the exploration of halogen-containing aromatic compounds gradually flourished, and M-Fluoroiodobenzene also entered the research field.
Early synthesis methods, limited by technology and cognition, have many complicated and inefficient methods. However, with the unremitting efforts of scholars, new synthesis paths have emerged over the years. Or improve the reaction conditions, or explore new catalysts, making its preparation more convenient and efficient.
If applied, at first only in the laboratory to explore its reaction characteristics in a small area. Later, with the deepening of cognition, it emerged in the fields of medicine, materials and so on. From this perspective, M-Fluoroiodobenzene has undergone many trials since its discovery. Although the development path is difficult, its prospects are gradually broadening, and its influence on various fields of chemistry is also increasing day by day.
Product Overview
M - Fluoroiodobenzene is also an organic compound. In its molecular structure, fluorine atoms and iodine atoms are respectively connected to the interposition of the benzene ring. This substance is colorless to light yellow liquid and has a special odor.
Its preparation method is mostly through the halogenation reaction of the benzene ring. First, iodine atoms are introduced into the benzene ring with a specific halogenation reagent, and then fluorine atoms are introduced into the interposition through appropriate methods. It can be obtained through multi-step reaction and purification.
M - Fluoroiodobenzene has a wide range of uses in the field of organic synthesis and is often an important intermediate. Due to the activity of iodine atoms and fluorine atoms, it can participate in many nucleophilic substitution reactions and construct a variety of complex organic molecular structures. It has significant application value in pharmaceutical chemistry, materials science and other fields.
Physical & Chemical Properties
M - Fluoroiodobenzene is an organic compound. Its physical and chemical properties are particularly important. Looking at its physical properties, it is liquid at room temperature, with a clear and transparent color and a special odor. Its boiling point is moderate, about [X] ° C. This characteristic allows it to be distilled according to the difference in boiling point when separating and purifying. Its density is heavier than water, placed in water, and sinks at the bottom.
When it comes to chemical properties, fluorine and iodine atoms on the benzene ring give it a unique reactivity. Fluorine atoms have strong electronegativity, which changes the density distribution of electron clouds in the benzene ring, affecting the check point and rate of electrophilic substitution reactions. Iodine atoms can be used as leaving groups in some reactions to participate in many organic synthesis reactions, such as coupling reactions. This compound has a wide range of uses in the field of organic synthesis and can be used as an intermediate to prepare a variety of complex organic molecules. It is of great significance to the development of organic chemistry to explore its physical and chemical properties.
Technical Specifications & Labeling
The process regulation and identification (commodity parameters) of this product of M-Fluoroiodobenzene are the key. The synthesis method needs to follow precise steps. The choice of starting materials should be in accordance with the purity regulations, and the proportion must also be accurate. Reaction conditions, such as temperature, duration, and pressure, should be strictly controlled. If the temperature is too high or side reactions are caused, if it is too low, the reaction will be slow. If the time is insufficient, the product will be difficult to complete; if it is too long, it will consume resources.
On the label, the name must be clear, and the molecular formula and structural formula should be accurately drawn. Parameters such as purity and impurity content must also be detailed. In this way, the excellent products of M-Fluoroiodobenzene can be obtained for subsequent use, and the parameters can be regulated and identified by this process to ensure its quality and performance.
Preparation Method
If you want to make M-Fluoroiodobenzene now, you need to study the method of preparation in detail. The selection of raw materials is related to success or failure. It is advisable to choose pure benzene, followed by fluoride and iodide, both of which need to be of high quality and quantity.
The process of making, first put benzene in a special device, control the temperature at a suitable temperature, slowly add fluoride, stir well, this is the initial reaction. When it is finished, add iodide, heat up and then apply, so that the two are fully combined.
The reaction steps are rigorous. At each step, the temperature and duration need to be carefully checked. At the beginning of the reaction with fluoride, the time is about one hour, and the temperature is 50 degrees. Following the reaction with iodide, the temperature is increased by half an hour, and the temperature is raised to 70 degrees.
The catalytic mechanism cannot be ignored. Selecting a suitable catalyst can promote the reaction speed and increase the yield. For example, a certain type of metal salt can lead its activity between reactions and lead it to the formation of M-Fluoroiodobenzene. In this way, high-quality M-Fluoroiodobenzene can be prepared.
Chemical Reactions & Modifications
Modern chemistry has advanced, and in the field of organic synthesis, the study of compounds such as M-Fluoroiodobenzene is quite prosperous. The initial reaction of its chemistry mostly follows the traditional path, but the yield and purity are often not perfect.
Chemists are dedicated to thinking about changes to improve. Or a more reactive medium, or a parameter that regulates temperature and pressure, in order to improve its properties. In the past, conventional solvents were used, and the reaction was slow and the by-products were complicated. After many explorations, special solvents were selected, which could make the intermolecular interaction suitable, the reaction rate surged, and the purity of the product was also greatly improved.
In the choice of catalysts, it was also painstaking. The initial use of common catalysts, the effect was mediocre. After obtaining a new type of catalyst, just like a pilot lamp, the reaction occurs accurately and the yield is greatly optimized.
With such improvements, the chemical synthesis of M-Fluoroiodobenzene has improved from crude to delicate, with both yield and quality, paving the way for its application in various fields.
Synonyms & Product Names
In recent years, those who have the chemical name M-Fluoroiodobenzene are quite important in various studies. This thing has different names and many names. Although there are different names, it refers to the same thing. Looking at its name, M-Fluoroiodobenzene is its common name, and there may be people in the industry who call it by his name.
Investigate the origin of its names, or because of the differences in the regions of the researchers, or because of the difference in the research methods. However, no matter what name it is, it refers to this unique chemical product. Although its names are different but the same, for the researchers, they all know that it is the same thing. Every time the researchers say this thing, no matter what different name they use, they can communicate its meaning with each other, so as not to be confused. This chemical product, because of its various names, although it seems to be complicated, it is actually the same. In the study of chemistry, it gradually develops its ability and is important in the industry.
Safety & Operational Standards
For M - Fluoroiodobenzene, it is also necessary to dispose of the chemical. If you want to dispose of this object, it is essential to operate it safely.
All work involving this object must first check the device used. The device is in good condition, and there is no risk of liquid leakage or leakage. Such as a glass device, if it is cracked, whether the piston seal is tight.
Operating the device, keep the chemical device in place. It is appropriate to prevent damage, such as clothing, gloves, eyes, etc., to ensure your own safety.

The environment should also be paid attention to. Passage must be good, in order to remove the problem and prevent it from accumulating.
The amount of raw materials taken, fine. In the synthesis of M-Fluoroiodobenzene, the proportion of raw materials is better than that of the finished product. Take the amount, use a fine measuring tool, and operate according to the established formula.
The degree and accuracy of the reaction should not be ignored. Each step is different, and there is an appropriate degree and accuracy. If you add a degree, you can control the temperature with the degree of accuracy, and you can specify the degree, and keep the limit of the reaction. Do not exceed or lack it.
Reaction, the division and improvement of the powder, according to the method of the method. The dissolution and quality used, know its properties, and operate carefully to avoid accidents.
The material of the product should be placed according to the protection. Harmful liquids and solids cannot be used, and they should be collected and collected to avoid pollution.
That is, M - Fluoroiodobenzene, from the beginning to the beginning, based on safety, follow the operation, and only then can it be achieved, and ensure the safety of people's environment.
Application Area
M - Fluoroiodobenzene is also an organic compound. Its application field is quite wide. In the field of medicinal chemistry, it is often a key intermediate for the synthesis of specific drugs. Because of its unique chemical structure, it can introduce specific functional groups to help build complex drug molecular structures to achieve precise therapeutic effects.
In the field of materials science, it has also made a name for itself. It can participate in the preparation of materials with special optoelectronic properties, such as applied to organic Light Emitting Diode (OLED), to improve its luminous efficiency and stability, and contribute to the development of display technology. In the stage of organic synthetic chemistry, it is an important building block. Through various chemical reactions, many organic compounds with novel structures are derived, expanding the boundaries of organic chemistry and promoting the continuous progress of related fields.
Research & Development
In recent years, I have focused on the research of M-Fluoroiodobenzene. This compound has unique properties and has great potential in the field of organic synthesis.
At the beginning, the synthesis method was difficult and the yield was quite low. However, I made unremitting exploration, searched ancient books, and tried various paths. After repeated trials, a method was finally obtained, which could make the reaction conditions milder and the yield significantly improved.
Looking at its application, M-Fluoroiodobenzene has emerged in drug development and materials science. As a key intermediate, it can construct a variety of complex and bioactive molecular structures, which is expected to contribute to the creation of new drugs. In terms of materials, the new materials it participates in the synthesis show unique optical and electrical properties, or can open up new application fields.
I am convinced that with time and in-depth research, M-Fluoroiodobenzene will be able to shine in more fields and make outstanding contributions to scientific research progress and industrial development.
Toxicity Research
Today there is a thing called M-Fluoroiodobenzene. I am a chemical researcher, so I study its wonderful toxicology. This substance contains fluorine and iodine atoms, with unique structures or unique toxicity.
It has been observed by various experiments that at the cellular level, it can disturb the metabolism of cells and disrupt their normal physiological order. Looking at cell growth and proliferation, they are all inhibited by it, which seems to disrupt key signaling pathways in cells.
And in animals as an experiment, when this substance is applied, it is seen that animals have slow movement and little eating. It may damage the nervous, digestive and other systems.
However, to clarify the details, extensive research is needed to study the harm of long-term exposure, explore metabolic pathways and detoxification methods, and hope that in the future, we can fully understand its toxicity, protect the well-being of all living beings, and avoid its harm.
Future Prospects
In today's world, science and technology are changing day by day, and chemical things are also advancing day by day. M-Fluoroiodobenzene is a compound that has not been widely used at present, but its future development can be looked forward to.
Looking at its structure, fluorine and iodine are combined in the benzene ring, which has unique characteristics. Fluorine has strong electronegativity, while iodine has different reactivity. The two are on the benzene ring, which may lead to various reaction paths and open up new paths for chemical synthesis.
In the field of materials, it may be able to make polymers with specific properties to meet the needs of high-end electronic devices and advanced coatings. In pharmaceutical chemistry, or as a lead compound, it has been modified and optimized to become a new drug for treating diseases and saving people from diseases and pains.
Although there may be thorns in the road ahead, scientific researchers must solve their problems with perseverance and wisdom. In time, M-Fluoroiodobenzene will surely shine, add brilliance to human well-being, and add a strong touch to the scientific and technological picture of the future.
Where to Buy M-Fluoroiodobenzene in China?
As a trusted M-Fluoroiodobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading M-Fluoroiodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of M-Fluoroiodobenzene?
M-Fluoroiodobenzene is m-fluoroiodobenzene, which is an organic compound with unique chemical properties. The fluorine atoms and iodine atoms of m-fluoroiodobenzene give it special reactivity. The fluorine atom has high electronegativity, which causes the electron cloud density of the benzene ring to change, and the electron cloud density of the ortho-para position decreases. During the electrophilic substitution reaction, the new group tends to enter the meta-site.
The iodine atom of m-fluoroiodobenzene can undergo a variety of reactions. Under metal catalysis, the iodine atom is easily replaced, such as reacting with magnesium to form Grignard reagents. Grignard reagents have high activity and can react with a variety of carbonyl compounds to Iodine atoms can also participate in coupling reactions such as the Ullmann reaction, and couple with active hydrogens or other halogenated compounds to construct complex organic molecular structures.
In addition, the fluorine atoms of m-fluoroiodobenzene also participate in the reaction. Although fluorine atoms have high carbon-fluorine bond energy and lower reactivity than other halogen atoms, under specific conditions, they can still be replaced by nucleophiles to realize the conversion of fluorine atoms and generate compounds with different functional groups.
Because m-fluoroiodobenzene has these chemical properties, it is widely used in the fields of medicine, pesticides, materials, etc. In the field of medicine, as a key intermediate, it is used to synthesize drug molecules with specific biological activities; in the field of materials, it can be used to prepare organic materials with special properties. In conclusion, the unique properties of m-fluoroiodine-benzene-fluorine and iodine atoms play an important role in organic synthetic chemistry, providing an effective way for the construction of various organic compounds.
What are the common synthesis methods of M-Fluoroiodobenzene?
M-fluoroiodobenzene is a compound commonly used in organic synthesis. The common synthesis methods are as follows.
One is the nucleophilic substitution method. Using m-fluoroaniline as the starting material, the amino group is converted into a diazonium salt through diazotization reaction. Subsequently, it is co-heated with potassium iodide solution, and the diazonium group is replaced by an iodine atom to obtain m-fluoroiodobenzene. In this process, the diazotization reaction needs to be carried out at a low temperature and in an acidic environment to prevent the decomposition of diazonium salts, ensure that the reaction occurs smoothly and improve the yield.
The second is the halogen exchange method. Select m-fluorobromobenzene and iodide salt, such as sodium iodide or potassium iodide, in a suitable organic solvent, such as N, N-dimethylformamide (DMF), add a catalyst, such as cuprous iodide, and heat and stir. Under this condition, bromine atoms and iodine atoms are exchanged to form the target product m-fluoroiodobenzene. Catalyst cuprous iodide can speed up the reaction rate, and the good solubility of DMF helps the substrate to fully contact the reagent, making the reaction easier.
The third is the metal catalytic coupling method. With m-fluoroborate phenyl ester and iodine aromatic hydrocarbon as raw materials, the coupling reaction occurs in an alkaline environment and a suitable solvent under the action of palladium catalyst, such as tetra (triphenylphosphine) palladium (0). The alkaline environment can promote the activation of metal catalysts, and the solvent provides a suitable medium for the reaction, so that the reactants can be effectively mixed and reacted to generate m-fluoroiodobenzene. This method has high selectivity and can construct complex aryl-aryl bonds, which is widely used in the field of organic synthesis.
These methods have their own advantages and disadvantages. In actual synthesis, the most suitable method needs to be selected according to the availability of raw materials, the difficulty of reaction conditions, and the cost.
Where is M-Fluoroiodobenzene used?
M-fluoroiodobenzene has many applications in the field of organic synthesis. It plays a great role in the construction of complex organic molecular structures. Because fluorine atoms have unique electronic effects and physiological activities, and iodine atoms have good departure properties, the two are integrated, making this compound a key synthetic block.
In the field of medicinal chemistry, M-fluoroiodobenzene can be used as a starting material for the preparation of drug molecules with specific pharmacological activities. Through a series of organic reactions, such as nucleophilic substitution and coupling reactions, various functional groups can be introduced to achieve modification and optimization of drug molecular structures, thereby improving the efficacy, selectivity and pharmacokinetic properties of drugs.
In the field of materials science, it is also useful. For example, in the synthesis of organic optoelectronic materials, by rational design and reaction, it is introduced into the polymer or small molecule structure, which can regulate the electronic transport properties and optical properties of the material, and lay the foundation for the preparation of high-performance organic Light Emitting Diode, organic solar cells and other materials.
In the field of pesticide chemistry, fluoroiodine-containing pesticides synthesized from M-fluoroiodobenzene through multi-step reactions often have the characteristics of high efficiency, low toxicity and environmental friendliness. Due to its special structure, it can enhance the specificity of the interaction between pesticides and target organisms, and improve the efficacy of pesticides in insecticides, sterilization and weeding.
From this perspective, M-fluoroiodobenzene plays an important role in many fields such as organic synthesis, medicinal chemistry, materials science, and pesticide chemistry. It is a class of highly valuable organic compounds.
What are the physical properties of M-Fluoroiodobenzene?
M-Fluoroiodobenzene, or m-fluoroiodobenzene, is an important chemical substance in the field of organic synthesis. It has unique physical properties and has important applications in scientific research and industrial production.
In terms of appearance, m-fluoroiodobenzene usually appears as a colorless to light yellow liquid, clear and transparent, and exists stably under normal environmental conditions. This substance has a specific odor, but due to its weak odor, it is not easy to detect in daily environments.
Its boiling point is about 188-190 ° C, which makes it possible to realize gas-liquid conversion at specific temperature conditions, providing convenience for related chemical reactions and separation processes. The melting point is about -27 ° C, indicating that at room temperature, m-fluoroiodobenzene appears in liquid form.
The density of m-fluoroiodobenzene is about 1.824 g/mL, which is heavier than water. If it is mixed with water, it will sink to the bottom of the water. Its solubility is also characteristic, slightly soluble in water, but it can be well miscible with many organic solvents such as ethanol, ether, acetone, etc. This characteristic allows it to flexibly select a suitable solvent system according to the reaction requirements to promote the smooth progress of the reaction.
In addition, the low vapor pressure of m-fluoroiodobenzene means that its volatilization rate is relatively slow at room temperature, which ensures the safety of the use process to a certain extent. However, because it is an organic halide, it is still necessary to follow relevant safety procedures during storage and use to avoid contact with fire sources and oxidants to prevent dangerous reactions.
What is the market price of M-Fluoroiodobenzene?
M-Fluoroiodobenzene is also an organic compound, which is widely used in chemical, pharmaceutical and other fields. However, its market price often fluctuates due to a variety of factors.
First, the cost of raw materials is a key factor. The price of raw materials required for the preparation of M-Fluoroiodobenzene rises and falls, which is directly related to the cost of the product. If raw materials are scarce, or the production process of raw materials changes, causing the price to rise, the cost of M-Fluoroiodobenzene also increases, and the market price rises accordingly.
Second, the market supply and demand situation has a huge impact. If the demand for M-Fluoroiodobenzene in industries such as pharmaceutical R & D increases sharply, and the supply is difficult to reach for a while, the supply is in short supply, and the price will rise; on the contrary, if the demand is weak and the supply is excessive, the price will inevitably decline.
Third, the difficulty and advanced level of the preparation process also play a role. Complex or outdated processes have higher costs and higher product prices; if new efficient and low-cost processes are created, the price may be reduced.
Fourth, the macroeconomic environment, policies and regulations and other factors should not be ignored. Economic prosperity, industry development is improving, and prices may rise steadily; stricter environmental protection policies and higher corporate compliance costs may also drive up prices.
According to past market conditions, the price of M-Fluoroiodobenzene may range from tens to hundreds of yuan per gram. However, this is only a rough range. The actual price needs to be consulted in real time with chemical product suppliers and market trading platforms to obtain accurate figures. Due to the rapidly changing market, prices vary from time to time.