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M-Chlorofluorobenzene

M-Chlorofluorobenzene

Hongda Chemical

Specifications

HS Code

176371

Chemical Formula C6H4ClF
Molar Mass 128.546 g/mol
Appearance Colorless to light - yellow liquid
Odor Aromatic odor
Density 1.224 g/cm³ at 25 °C
Boiling Point 128 - 129 °C
Melting Point -45 °C
Flash Point 31 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether

As an accredited M-Chlorofluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100 - gram bottle of M - chlorofluorobenzene, well - sealed for chemical storage.
Storage M - chlorofluorobenzene should be stored in a cool, well - ventilated area, away from heat sources and ignition points as it is flammable. Keep it in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents and reactive chemicals. Ensure the storage facility has proper spill - containment measures to handle any potential leaks safely.
Shipping M - chlorofluorobenzene is shipped in well - sealed, corrosion - resistant containers. It's transported under regulated conditions, following strict safety protocols due to its chemical nature, ensuring secure delivery.
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M-Chlorofluorobenzene M-Chlorofluorobenzene
General Information
Historical Development
M-Chlorofluorobenzene is an organic compound, and its historical development is quite significant. In the past, organic chemistry was first developed, and chemists focused on the exploration of various compounds. At that time, the research conditions were simple, and it was difficult to analyze the structure and properties of such compounds.
With the passage of time, science and technology have advanced, and analytical methods have become increasingly sophisticated. The birth of spectroscopy technology has helped chemists gain insight into the internal structure of M-Chlorofluorobenzene. Synthetic methods have also been continuously innovated, from the initial complicated and inefficient steps to the current concise and efficient process.
In the early days, this compound was expensive to produce and the yield was scarce, and it was only used for a small number of experimental studies. However, under the promotion of science and technology, the preparation process is optimized, the cost is reduced, the output is greatly increased, the application field is expanded, and it has emerged in many fields such as material science and drug research and development, leaving a deep imprint in the development of chemistry.
Product Overview
"Product Overview of M-Chlorofluorobenzene"
M-Chlorofluorobenzene is a significant chemical in the field of organic synthesis. Its properties are colorless and transparent liquids with a special odor. This substance is stable at room temperature and pressure, but it is dangerous to burn in case of open flames, hot topics, etc.
Its unique structure, chlorine and fluorine atoms are cleverly connected to the benzene ring interposition. With this structure, it shows unique activity in many reactions. In fine chemicals, it is often used as a key intermediate.
The preparation method is obtained by a specific halogenation reaction. After a series of precise controls and conditions, high-purity products can be obtained.
It has a wide range of uses, in the field of pharmaceutical synthesis, to help the research and development of a variety of specific drugs; in the creation of pesticides, it is also a key ingredient, which can enhance the efficacy of pesticides.
M-Chlorofluorobenzene, with its unique nature, exquisite structure and multiple uses, occupies an important position in the chemical industry world, and has broad prospects. It will attract more researchers to explore in depth in the future.
Physical & Chemical Properties
M-Chlorofluorobenzene, organic compounds are also. Its physical and chemical properties are quite worthy of our generation's research.
In terms of its physical rationality, under room temperature, M-Chlorofluorobenzene a colorless liquid with a special odor. Its boiling point is suitable for a certain degree, which is related to the difficulty of its gasification. And its density is also a specific value. In experiments such as liquid mixing, this property has a great impact.
As for chemistry, the presence of chlorine and fluorine atoms in its molecular structure gives the compound a unique reactivity. The conjugated system of benzene ring gives it a certain stability. In many chemical reactions, such as nucleophilic substitution, electrophilic substitution, etc., due to these properties, different reaction paths are presented. The understanding of its physical and chemical properties is of great significance in the fields of organic synthesis and materials science, and can provide a solid theoretical foundation for related research and applications.
Technical Specifications & Labeling
今有M - Chlorofluorobenzene之制备,工艺规格与标识(产品参数)至为关键。其工艺需循严谨之规,原料配比务必精准,反应温度、时长皆须严格把控。于反应釜中,以特定之催化剂,使诸反应物依序混合,维持适宜之压强,方可确保反应顺遂。

至于标识,产品参数当详明。纯度需达极高之标,杂质含量务必严控。外观、气味等亦需清晰界定。包装之上,当以显著之字,标其名称、含量、危险警示等信息。如此,方能使此产品于市场流通之际,为使用者明晰其特性,保障安全与质量,于化工领域得以妥善应用。
Preparation Method
The raw materials and production process of this method of making M-Chlorofluorobenzene are the key. Usually a specific halogenated aromatic hydrocarbon is used as the initial raw material, such as a chlorinated aromatic hydrocarbon interacting with a fluorine-containing reagent. The reaction step is to first make the halogenated aromatic hydrocarbon in a specific solvent, and with an appropriate amount of fluoride under the help of a catalyst, it is heated to a suitable temperature to initiate a nucleophilic substitution reaction. This reaction requires precise temperature control and duration to ensure that the reaction proceeds in the direction of generating the target product.
As for the catalytic mechanism, the selected catalyst can effectively reduce the activation energy of the reaction and accelerate the substitution process of halogen atoms. After this reaction, the initial product contains impurities, and then it is purified by distillation, extraction and other purification processes to obtain high-purity M-Chlorofluorobenzene. Therefore, it is a more complete method for preparing this product.
Chemical Reactions & Modifications
After studying the chemical changes of M-Chlorofluorobenzene, I found the reaction and properties of M-Chlorofluorobenzene interesting. The reaction of this compound often depends on the reagents used and the reaction conditions.
Under specific reaction environments, the activities of chlorine and fluorine in M-Chlorofluorobenzene vary. Chlorine atoms are relatively easy to leave, which can lead to nucleophilic substitution reactions. When encountering nucleophilic reagents, chlorine is often replaced by them, and new compounds are generated, which is an important characteristic of the reaction.
However, its properties are not static. By adjusting the reaction temperature, solvent, or adding a catalyst, the reaction path and product can be changed. For example, increasing the temperature or using polar solvents can sometimes accelerate the reaction rate and affect the selectivity of the product. This is all due to the careful investigation of optimizing the chemical application of M-Chlorofluorobenzene. Therefore, it can be known that the adjustment of its reaction and properties is the key to chemical research, which can lead to the creation and application of more novel compounds.
Synonyms & Product Names
M-Chlorofluorobenzene is an organic compound. Its synonymous name, also known as m-chlorofluorobenzene. This substance is widely used in the field of chemical industry.
In industrial preparation, it is often used in a specific reaction to polymerize the reactants, and after several transformations, it is obtained. Its properties are stable and have special physical and chemical characteristics.
The name of the product sold in the market, or slightly different depending on the manufacturer, refers to this M-Chlorofluorobenzene. It is an important raw material in the synthesis of new substances, pharmaceutical research and development and other fields, just like masonry is indispensable in Guangsha. We study the synonyms and trade names of this object to clarify its change of appellation, which is beneficial to both academia and industry.
Safety & Operational Standards
"M-Chlorofluorobenzene Product Safety and Operation"
The husband of M-Chlorofluorobenzene is also a chemical product. If you want to make good use of it, you must know that it is safe and safe to operate.
The first word is safety. This product has a certain degree of danger. It can harm people if you eat it, smell it, or eat it. Therefore, it should be stored in it, pass it, and avoid the source of fire. The equipment must be kept secret to prevent leakage. If you are not careful, you must quickly order those in it to avoid a safe place and must not approach it. Clean it, wear protective equipment, such as gas masks, protective clothing, etc., and do not make skin, eyes, etc. contact.
Next operation. In the operation, those who work hard must be well-trained in order to eliminate harmful effects. In the operation room, it is necessary to use the equipment of the machine, and it must not be left behind. Measure the quality of the machine, and the quality of the machine must not be poor. And the mixing must be in a specific order, and it cannot be done.
Furthermore, in case of an accident, such as leakage, fire, etc., the machine must be determined according to the policy of the machine. If the leakage is blocked quickly, it must be cleared; if the fire is used with appropriate fire equipment, it must not be done blindly.
In other words, M-Chlorofluorobenzene is useful for chemical research, but its safe operation cannot be ignored. Those who work hard must guard it, so as to ensure their own safety, and also to protect the environment, so that this product can be used properly and harm the world.
Application Area
M - Chlorofluorobenzene is also an organic compound. Its application field is quite wide. In the field of pharmaceutical synthesis, it is often a key intermediate. Due to its unique chemical structure, it can participate in many reactions, help create new drugs, and cure various diseases.
In the field of materials science, it also has important functions. It can be synthesized through a specific synthesis path to obtain polymer materials with excellent performance, or enhance the stability of materials, or endow special optical properties, which can be used in electronic devices, optical instruments, etc.
And in agricultural chemistry, M - Chlorofluorobenzene can be used as a raw material for synthesizing pesticides. The prepared pesticides can effectively resist pests and diseases, ensure the robust growth of crops, and increase agricultural output, which is of great benefit to agricultural development. All of this highlights the important value of its application in multiple fields.
Research & Development
Today there is M-Chlorofluorobenzene, and we study its research and development in detail as chemical researchers. M-Chlorofluorobenzene has great potential in the field of organic synthesis. Its structure is unique, and the substitution of chlorine and fluorine atoms gives it special chemical properties.
At the beginning of the research, we focused on the synthesis path. After various experiments, we found suitable methods to optimize the reaction conditions and improve the yield and purity. In this process, we carefully study the reaction mechanism and gain insight into each step change.
Furthermore, consider its application and expansion. Due to its special properties, it is expected to emerge in the creation of medicines and pesticides. Try to react with various compounds and explore new derivatives, hoping to discover unique active substances.
Looking to the future, continue to improve synthesis technology, reduce costs and increase efficiency. Deeply tap the application potential and expand to more fields, such as materials science. In time, M-Chlorofluorobenzene will surely shine in scientific research and industry, and promote progress in related fields.
Toxicity Research
The toxicity of M-Chlorofluorobenzene is related to people's livelihood and the environment, which cannot be ignored. This substance has many applications in industry, but the study of its toxicity is quite important.
Taste all substances, the appearance of toxicity, or harmful to life, or sewage. The properties of M-Chlorofluorobenzene, after various tests, it can be seen that it may disturb the metabolism of organisms and disrupt their physiological order.
In animal tests, small agents enter the body, or cause slight discomfort. If the amount accumulates slightly, it can be seen that the organs are damaged. And in the environment, the degradation is slow, and it is easy to accumulate in water and soil, causing ecological changes.
Therefore, when studying its toxicity in an all-round way, exploring the mechanism of its harm to organisms, and clarifying the path of its dissemination, it can be used to prevent disasters, ensure the safety of people's livelihood, protect the environment, and reduce the harm caused by industry.
Future Prospects
M - Chlorofluorobenzene is also a chemical. There is nothing to be said about the future prospects of this compound.
This compound has power in many fields. In the field of materials science, it can be the basis of new materials, and its characteristics can be used to assist in the research of high-performance and special-function materials, in order to meet the needs of future technologies, such as sub-devices, aerospace, and make them more powerful and have special functions.
In research and development, it may also be of great use. Because of its special molecular properties, it may provide a way to help overcome diseases and improve the health of the world.
However, to develop its capabilities, it still needs to be unremitting exploration by scientists. Only by carefully studying its properties and deeply studying its rationale can we fully evaluate its unrealized value, so that this compound can be used for all kinds of things, and it can be widely used for the benefit of the world.
Where to Buy M-Chlorofluorobenzene in China?
As a trusted M-Chlorofluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading M-Chlorofluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of M-Chlorofluorobenzene?
M-chlorofluorobenzene is also an organic compound. It has unique chemical properties.
In terms of reactivity, the presence of the benzene ring makes it aromatic. Chlorine and fluorine disubstituents have an effect on the electron cloud density distribution of the benzene ring. Fluorine atoms have strong electronegativity and have an electron-absorbing induction effect, which reduces the electron cloud density of the benzene ring; chlorine atoms also have an electron-absorbing induction effect, but it is weaker. The effect of these two, causing the electron cloud density of the benzene ring to decrease more relative to the meta-position, so during the electrophilic substitution reaction, the meta-position is more vulnerable to the attack of electrophilic reagents.
In the electrophilic substitution reaction, halogenation, nitrification, sulfonation and other common reactions can occur. For example, when nitrified, the nitro group tends to enter the meso-site to form m-nitrochlorofluorobenzene.
Its chemical stability is quite high, due to the conjugated system of the benzene ring, which imparts structural stability. In case of strong oxidants, high temperatures or special catalysts, it can also initiate reactions.
Physically, it is a colorless liquid with a special odor. It is insoluble in water and is miscible with common organic solvents such as ethanol and ether due to relatively weak molecular polarity. The melting point and boiling point are affected by intermolecular forces. Due to the relative mass and structural characteristics of molecules, there is a specific melting and boiling point range.
This compound is widely used in the field of organic synthesis and can be used as an intermediate. It can be converted into various complex organic compounds containing fluorine and chlorine through various reactions, and is of great significance in the pharmaceutical, pesticide, material and other industries.
What are the physical properties of M-Chlorofluorobenzene?
M-chlorofluorobenzene is also an organic compound. It has unique physical properties, let me describe it in detail for you.
Looking at its properties, it is a colorless and transparent liquid under normal circumstances, like a clear spring, clear and free of impurities. This substance is volatile and light in the air. If it curls green smoke, it slowly rises. Its smell is unique, although not pungent, it also has a unique fragrance, which is impressive to smell.
As for its melting point, the melting point is about -46 ° C, just like the cold of winter, and the temperature is condensed at this point. The boiling point is about 129-130 ° C. If it is heated by fire, it will turn into a gaseous state and soar into the air.
In terms of solubility, it is insoluble in water, just like the incompatibility of oil and water, and the two are distinct. However, in organic solvents, such as ethanol, ether, etc., they can dissolve each other, just like water emulsion blends and fuses into one.
The density is heavier than water. If it is co-placed with water in a device, it will sink to the bottom of the water, like a pearl falling into an abyss. Its refractive index also has a specific value. Where it may be available in fields such as optical research, light is refracted through it, presenting a unique optical phenomenon.
In addition, the stability of M-chlorofluorobenzene is acceptable. Under normal conditions, it is not prone to violent chemical reactions. However, when it encounters strong oxidizing agents, strong acids, strong alkalis, and other substances, it will also change, just like a calm lake thrown into boulders, causing layers of ripples.
What are the main uses of M-Chlorofluorobenzene?
M-Chlorofluorobenzene (M-Chlorofluorobenzene) is also an organic compound. It has a wide range of uses and has important applications in various fields of chemical industry.
First, in the synthesis of medicine, M-Chlorofluorobenzene is often the key raw material. With a specific reaction path, it can be introduced into the molecular structure of the drug. Because of its unique chemical structure, it can endow the drug with special activity and properties. For example, in the creation process of some antibacterial drugs, the clever use of M-Chlorofluorobenzene can enhance the inhibitory effect of the drug on specific bacteria and enhance the efficacy and selectivity of the drug.
Second, in the field of pesticides, M-Chlorofluorobenzene is also indispensable. After a series of chemical reactions, highly efficient pesticide varieties can be prepared. Such pesticides can effectively kill pests and inhibit the growth of pathogens by virtue of the chemical properties imparted by M-chlorofluorobenzene, and have relatively little impact on the environment, helping to stabilize and high yield in agriculture.
Third, in the field of materials science, M-chlorofluorobenzene can participate in the synthesis of special materials. For example, in the preparation of some high-performance plastics or polymers, the introduction of M-chlorofluorobenzene structural units can optimize the physical properties of the material, such as improving the heat resistance and corrosion resistance of the material, so as to meet the strict requirements of special industrial scenarios.
Furthermore, in the dye industry, M-chlorofluorobenzene can be used as an important intermediate for the synthesis of new dyes. With its unique structure, dye products with excellent dyeing properties and good color fastness can be developed to meet the needs of high-quality dyes in textile, printing and dyeing industries.
In short, M-chlorofluorobenzene, with its unique chemical structure, plays a key role in many fields such as medicine, pesticides, materials and dyes, and is of great significance to promote the development of related industries.
What are the preparation methods of M-Chlorofluorobenzene?
For M-chlorofluorobenzene, there are many methods for preparing organic compounds, and each method has its own advantages and disadvantages, and the user needs to choose according to the situation. The common methods are as follows:
First, the halogenation method. Start with fluorobenzene and obtain it by chlorination. First, the fluorobenzene is placed in a suitable reactor, and a suitable chlorinating agent is selected, such as chlorine gas. When there is a catalyst, such as anhydrous ferric chloride, it should be heated up. The reason is that the chlorine atom replaces the hydrogen atom on the benzene ring, and due to the positioning effect of fluorine, more intermediate products can be obtained. The advantage of this method is that the raw material is easy to cause, and the steps are still simple. However, there are also deficiencies. The product or impurities containing ortho and para-impurities require fine separation.
Second, the diazotization method. Based on m-chloroaniline, first make it into a diazonium salt. Dissolve m-chloroaniline into an acid solution, such as hydrochloric acid, cold to low temperature, slowly add sodium nitrite solution to obtain a diazonium salt solution. After adding fluoroboronic acid, the interchlorobenzene diazofluoroborate precipitates. After separation, drying, and then heating decomposition, M-chlorofluorobenzene is obtained. This way is wonderful, with good selectivity and high product purity. However, the process is slightly complicated, and the reagents used may be dangerous, requiring careful operation and high cost.
Third, the Grignard reagent method. With m-chlorobromobenzene as the starting point, the Grignard reagent, that is, m-chlorophenyl magnesium bromide, was prepared. The m-chlorobrobenzene was dissolved in anhydrous ether, and magnesium chips were added to initiate the reaction. After reacting with fluorinated reagents, such as silver trifluoromethanesulfonate, under suitable conditions, the target product can be obtained. This method can accurately introduce fluorine atoms, and the yield can also be observed. However, it requires an anhydrous environment, strict requirements on equipment and operation, and high activity of reagents such as magnesium chips. Safety should be paid attention to in storage and use.
M-Chlorofluorobenzene what are the precautions during storage and transportation?
M-chlorofluorobenzene is also an organic compound. When storing and transporting, many matters must be paid attention to.
Store it first. This substance should be placed in a cool and ventilated warehouse, away from fires and heat sources. Because of its flammability, it may cause combustion and explosion in case of open flames and hot topics. The temperature of the warehouse should be controlled within an appropriate range to prevent danger caused by excessive temperature. And it should be stored separately from oxidizing agents, acids, and alkalis, and should not be mixed. Because M-chlorofluorobenzene and other such substances are prone to chemical reactions or dangerous accidents. The storage area should be equipped with suitable materials to contain leaks, so that if accidental leakage can be properly handled in a timely manner.
Second mention its transportation. Before transportation, make sure that the container is well sealed and there is no risk of leakage. During transportation, it should be stably loaded and unloaded to prevent damage to its container. Transportation vehicles must be equipped with the corresponding variety and quantity of fire-fighting equipment and leakage emergency treatment equipment. During driving, keep away from fire and heat sources, and do not stop in residential areas and densely populated places. If it is transported by road, drive according to the specified route. If it is transported by rail, it is strictly forbidden to slip.
In short, the storage and transportation of M-chlorofluorobenzene must strictly abide by safety regulations and operate with caution to prevent dangerous accidents and ensure the safety of personnel and the environment.