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Cyanopentafluorobenzene

Cyanopentafluorobenzene

Hongda Chemical

Specifications

HS Code

114393

Chemical Formula C6F5CN
Appearance Colorless liquid
Boiling Point 127 - 128 °C
Melting Point -22 °C
Density 1.55 g/cm³
Vapor Pressure 1.33 kPa (25.2 °C)
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents
Flash Point 37 °C
Refractive Index 1.388

As an accredited Cyanopentafluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing Cyanopentafluorobenzene, 500g, packaged in a sealed, corrosion - resistant container.
Storage Cyanopentafluorobenzene should be stored in a cool, well - ventilated area away from heat sources and open flames. Keep it in a tightly closed container, preferably made of materials resistant to corrosion by this chemical. Store it separately from oxidizing agents and other incompatible substances to prevent dangerous reactions. Ensure proper labeling for easy identification.
Shipping Cyanopentafluorobenzene is shipped in specialized, tightly - sealed containers to prevent leakage. It follows strict hazardous chemical shipping regulations, ensuring proper handling during transit to safeguard safety and the environment.
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Cyanopentafluorobenzene Cyanopentafluorobenzene
General Information
Historical Development
"A History of Cyanopentafluorobenzene"
Cyanopentafluorobenzene is also a chemical substance. Its origin and research originated in the past. At the beginning, the field of chemistry was not as prosperous as it is today, and the exploration of various things was difficult.
At that time, the researchers were exhausted in the mystery of chemistry. As for cyanopentafluorobenzene, they also went through many trials and errors. Early attempts, or because the method was not good, the equipment was not refined, and the results were not obvious.
However, the researchers' ambition has not been lost, and they have been passed down through successive generations. With the passage of time, the technology is gradual, and the understanding is deeper. As a result, the properties and systems of cyanopentafluorobenzene have made considerable gains. Its production method is becoming more and more complete, and its use is also becoming more and more extensive. It has emerged in the fields of medicine and materials. The arduous exploration of the past has finally resulted in the remarkable development of this substance today, which is a good example of chemical evolution.
Product Overview
Today there is a thing called Cyanopentafluorobenzene. It is a chemical product with unique characteristics. The appearance of this substance is [here if there is an appearance description can be supplemented], the properties are stable, and it shows extraordinary use in many chemical reactions.
Its preparation method is made by [If you know the preparation method briefly]. In the industrial field, it is widely used, or it is a key raw material for the synthesis of other substances, or it plays a role in [specific industrial link 1], or helps [specific industrial link 2].
Cyanopentafluorobenzene also plays an important role in the path of scientific research and exploration. Many scholars study its characteristics and applications, hoping to open up new frontiers, add bricks to the chemical field, promote the progress of science and technology, and seek the well-being of the world.
Physical & Chemical Properties
Taste the wonders of chemical industry, all kinds of substances have their own characteristics. There are Cyanopentafluorobenzene of this substance today, and its physical and chemical properties can be investigated.
Looking at its shape, under normal conditions, it is either a clear liquid or a crystalline body. Its boiling point and melting point are all related to the strength of its intermolecular force. For the boiling point, it is necessary to observe the difficulty of the molecule breaking free from the liquid phase binding; for the melting point, it is related to the stability of the lattice.
On its chemistry, the cyanyl group coexists with the pentafluorobenzene ring, which makes the molecule have unique reactivity. Cyanyl can lead to nucleophilic and electrophilic changes, while the pentafluorobenzene ring is different in the reactions of aromatic substitution. Or it can be embraced with nucleophilic reagents to generate new carbon-carbon and carbon-hetero bonds, adding thousands of possibilities in the process of organic synthesis. Its chemical stability is also enhanced by the electronegativity of fluorine atoms. Among common reagents, it keeps its original state and changes when it is suitable for the machine. It is also a treasure in the chemical industry.
Technical Specifications & Labeling
"Process Specifications and Labeling (Product Parameters) "
Cyanopentafluorobenzene is specific and has its use in the field of chemical industry. Its process specifications, the first preparation method. It needs to be obtained through several processes according to the precise ratio and suitable temperature and pressure. The raw materials used must be pure, and the impurities must be controlled at the micro.
As for the label (product parameters), the color is pure and transparent, and there is no variegated dye. Its boiling point and melting point are fixed, and the error cannot exceed a millimeter. The standard of purity should reach a very high level to ensure the best quality. The impurity content is detailed in the label, and it must be checked. In this way, this product can be fully effective when applied, contributing to the prosperity of the industry.
Preparation Method
In order to Cyanopentafluorobenzene this product, the raw materials and production process, reaction steps and catalytic mechanism are the key. Take pentafluorobromobenzene as the initial raw material, use cuprous cyanide as the cyanide agent, and heat it to 150-180 ℃ in N, N-dimethylformamide solvent. This is a nucleophilic substitution reaction. The bromine atom activity of pentafluorobromobenzene is quite high, and the cyanide negative ion of cuprous cyanide attacks nucleophilic, so it forms a Cyanopentafluorobenzene.
The reaction steps are as follows: first put pentafluorobrobenzene and cuprous cyanide into the reactor in a certain proportion, inject an appropriate amount of N, N-dimethylformamide, stir and mix thoroughly. Heat up to the specified temperature After the reaction is completed, the by-product cuprous bromide is removed by cooling and filtration, and the filtrate is purified by vacuum distillation to obtain pure Cyanopentafluorobenzene.
The catalytic mechanism is that cuprous cyanide provides cyanide negative ions, and its electron-rich nature promotes the smooth occurrence of nucleophilic substitution reactions, which greatly improves the reaction efficiency and yield, so Cyanopentafluorobenzene is obtained.
Chemical Reactions & Modifications
Taste the wonders of chemical industry, related to reaction and modification, it is a wonder of creation. Today there are Cyanopentafluorobenzene of this product, its chemical reaction and performance improvement are worth studying.
If you want to change it, you should study its reaction mechanism. Or at a specific temperature and pressure, with appropriate catalysts, rearrange its molecular structure, or combine with others to produce new substances. If it encounters an active group, its chemical activity can be changed by nucleophilic substitution.
As for the change of performance, its stability can be enhanced to adapt to harsh environments; or its solubility can be adjusted to facilitate process operation. All this depends on fine design and repeated tests. Through subtle reactions, the performance of Cyanopentafluorobenzene is optimized, which can add bricks and mortar to many fields and achieve a new appearance of chemical industry.
Synonyms & Product Names
There is a thing called Cyanopentafluorobenzene. This thing is quite important in the field of chemistry. Its aliases are also numerous, and each has its own name.
This thing is unique and has a wide range of uses. Or it is used in various synthesis, which is an important corner of the chemical industry; or it helps scientific research to advance, opening up a new path of exploration.
The name of its product also varies from time to place. However, no matter what it is called, it refers to this Cyanopentafluorobenzene. In my chemical research, I often encounter this thing, and I know its importance is very important. Every time I use it as a basis, I carry out various experiments, hoping to gain something, in order to understand the wonders of chemistry and explore the wonders of matter. It is hoped that by leveraging its power, it will contribute to the chemical industry and make achievements.
Safety & Operational Standards
"Code of Safety and Operation of Cyanopentafluorobenzene"
Cyanopentafluorobenzene is also a chemical product. Safety and operation standards are the key to its preparation, storage and use.
At the beginning of preparation, all raw materials must be accurately weighed, and their equipment should be clean and dry. The temperature, pressure and other conditions of the reaction environment must be strictly controlled. The reaction device should be stable and airtight to prevent the material from escaping. Operators need to wear appropriate protective equipment, such as gas masks, protective clothing, etc., to prevent possible hazards.
When storing, cyanopentafluorobenzene should be placed in a cool, dry and well-ventilated place. Keep away from sources of fire and heat, and avoid co-storage with oxidizing agents, reducing agents, etc., to prevent dangerous chemical reactions. Storage containers must be tightly closed and should be clearly marked to clearly indicate their characteristics and hazards.
As for the use, there should be good ventilation equipment in the operation room to disperse possible harmful gases. When taking it, the action should be steady and accurate to avoid spilling. If you accidentally come into contact with skin or eyes, rinse with plenty of water immediately and seek medical treatment immediately. After use, the remaining materials and utensils should be properly disposed of and cleaned up, and should not be disposed of at will.
Therefore, during the preparation, storage and use of cyanopentafluorobenzene, strict adherence to safety and operating standards is required to ensure the well-being of personnel and the environment, and to ensure the safe and reasonable application of this chemical product.
Application Area
Cyanopentafluorobenzene, the wonders of chemical engineering are also. Its application field, the development of the industry. In the field of synthesis, it is often difficult to achieve the best results, and it can be used to create more and more delicate reactions, helping to improve the molecular engineering of the world. In the field of materials, there are also extraordinary examples, which can be used to add watts to materials with special properties.
Furthermore, in the field of research, Cyanopentafluorobenzene may play an important role in helping new technologies. Its special properties, or can be used to develop new ideas of molecular engineering. In addition, this chemical engineering has a lot of power in the field of multiple applications, such as the pearl of the deep sea, which needs to be explored by researchers step by step, in order to reveal more secrets, for the benefit of human science and improve life.
Research & Development
In recent years, the industry of chemical industry has been researching, and it has been a lot of effort to Cyanopentafluorobenzene this thing. Its properties are unique, and it has a wide range of uses. It can involve various fields of medicine and materials, and the prospect is very promising.
At the beginning, its structure was analyzed, its characteristics were explored, and its physicochemical properties were known through various experiments. However, the preparation method is very difficult and expensive, which restricts its wide use.
So he gathered the wisdom of the people and studied the improved technique. After months of work, he tried various paths, or adjusted the conditions of the reaction, or changed the raw materials used, hoping to get a good method. In the end, the method was obtained, which was simpler and cheaper than before.
Today, Cyanopentafluorobenzene research, although there is progress, but to be widely used in the world, still need to work hard. In the future, we can strive for excellence, shine in the field of industry, and contribute to the progress of chemical industry.
Toxicity Research
The chemical industry is related to people's livelihood, but the study of poisons in it should not be careless. There are Cyanopentafluorobenzene this substance today, and in chemical products, the study of its toxicity is very important.
Looking at this substance, its molecular structure is unique, accompanied by pentafluoride and connected by cyanide groups. Although it may be useful in some industrial processes, the hidden dangers of toxicity cannot be ignored. After various experiments, white pigs and guinea pigs were used as tests to observe their state after ingestion or exposure. See the body of the test, there is fatigue, eating less, and even damage to the organs.
It can be seen that Cyanopentafluorobenzene have certain toxicity. During production and use, we must strictly abide by the procedures and take protective measures to avoid poisoning living beings and harming health. Make sure to make the benefits of the chemical industry and not cover the danger of poisons to ensure the safety of all things.
Future Prospects
Cyanopentafluorobenzene, it is also a matter of transforming things. Today's things are unique, and they have extraordinary power in the field of development. Before they are developed, they can be used in research and development, and their characteristics may help create new technologies and save people. It can also be used in the field of materials to create special materials, which can be used in high-tech. Moreover, in the field of synthesis, it can also be used as a foundation for new reactions and expand the way of synthesis. This is a scene that has not yet been hoped for. Our researchers, unremitting research, hope to make Cyanopentafluorobenzene can be developed and used by the world, so as to create a grand future.
Where to Buy Cyanopentafluorobenzene in China?
As a trusted Cyanopentafluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading Cyanopentafluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of Cyanopentafluorobenzene?
Cyanopentafluorobenzene (Cyanopentafluorobenzene), as well as organic compounds, has a wide range of uses and is important in various fields of chemical industry.
First and medicinal chemistry. This compound is a key synthetic intermediate and can be used to create new drugs. Due to its unique chemical structure, it can endow drugs with special physical and chemical properties, such as enhancing the lipid solubility of drugs, making it easier to penetrate biofilms and improve bioavailability. Chemists use it as a basis and design complex drug molecular skeletons through exquisite reactions, which play a significant role in the development of antibacterial, antiviral, and anti-tumor drugs.
Second and material science. Cyanopentafluorobenzene can participate in the preparation of high-performance polymer materials. In the polymerization reaction, it can introduce special functional groups to improve the thermal stability, mechanical properties and chemical stability of the polymer. For example, the preparation of engineering plastics with high temperature resistance and chemical corrosion resistance is widely used in aerospace, electronics and electrical appliances. The materials made from it can withstand extreme environments and ensure the stable operation of equipment.
Furthermore, in organic synthesis chemistry. Cyanopentafluorobenzene is an important building block for organic synthesis. Through various reactions such as nucleophilic substitution and electrophilic substitution, it is coupled with other organic molecules to form organic compounds with diverse structures. Synthetic chemists use this to expand the structural types of organic molecules, providing rich possibilities for the creation of new substances, and promoting the continuous development of organic synthesis chemistry.
In the field of agricultural chemistry. Based on this compound, high-efficiency and low-toxicity pesticides can be developed. Its special structure helps pesticides to accurately act on target organisms, improve efficacy while reducing environmental impact, and contribute to the development of green agriculture.
In summary, cyanopentafluorobenzene plays an indispensable role in many fields such as medicine, materials, organic synthesis and agriculture. Its unique chemical properties provide strong support for innovation and development in various fields.
What are the physical properties of Cyanopentafluorobenzene?
Cyanopentafluorobenzene is also an organic compound. It has specific physical properties and is important in chemical, pharmaceutical and other fields.
Looking at its properties, under normal temperature and pressure, cyanopentafluorobenzene is a colorless to light yellow liquid with a special odor. Its boiling point is about 153-155 ° C. At this temperature, the substance gradually changes from liquid to gaseous. The melting point is about -31 ° C. Below this temperature, it is in a solid state.
Its density is heavier than water, about 1.59 g/cm ³, so when it is mixed with water, cyanopentafluorobenzene will sink underwater. And because of its molecular structure characteristics, it is slightly soluble in water, but can be well miscible with common organic solvents, such as ethanol, ether, acetone, etc. This characteristic makes it possible to choose an appropriate organic solvent to assist the reaction in organic synthesis reactions.
The vapor pressure of cyanopentafluorobenzene is also an important physical property. Vapor pressure characterizes the tendency of substances to volatilize. The vapor pressure of this compound has a specific value at a specific temperature, which affects its diffusion and evaporation rate in the environment. In chemical production sites, it is necessary to pay attention to its vapor pressure to properly handle it to prevent its volatilization from causing safety and environmental problems.
In addition, cyanopentafluorobenzene has certain stability, but under certain conditions, such as high temperature, strong acid base or the presence of specific catalysts, intracellular cyanide and fluorine atoms can participate in a variety of chemical reactions, exhibiting active chemical activity, which is the basis for the construction of various complex compound structures in organic synthesis.
Is Cyanopentafluorobenzene chemically stable?
Cyanopentafluorobenzene, the stability of its chemical properties, is related to many chemical matters. Looking at this compound, the cyanyl group is nucleophilic, and there are many fluorine atoms on the pentafluorobenzene ring. Fluorine, an element with extremely strong electronegativity, also has many fluorine atoms in the benzene ring, which causes the electron cloud density of the benzene ring to drop sharply, resulting in a sharp decrease in the electrophilic substitution reaction activity of the benzene ring. However, this structure also increases the stability of the molecule, because its bond energy is relatively high.
The cyanyl group is connected to the pentafluorobenzene ring, and the interaction between the two may affect the reactivity of the cyanyl group. Usually, the cyan In cyanopentafluorobenzene, the electron-withdrawing effect of the fluorine atom on the benzene ring may make the positive electricity of cyanocarbon stronger, theoretically increasing the activity of cyanophilic nucleophilic addition reaction. However, due to the coexistence of steric hindrance and electronic effect of fluorine atoms on the benzene ring, many reactions may require specific conditions to occur.
Under normal conditions, cyanopentafluorobenzene is relatively stable due to its special structure. In case of extreme conditions such as strong nucleophilic reagents, high temperatures, strong acids or strong bases, its structure may change and various chemical reactions occur. Its stability is not absolute and varies depending on the environment and reagents. Therefore, the stability of the chemical properties of cyanopentafluorobenzene requires a comprehensive review of the reaction conditions, reagent characteristics and many other factors to obtain a definitive conclusion.
What is Cyanopentafluorobenzene production method?
Cyanopentafluorobenzene is an important compound in the field of organic synthesis. The methods for its preparation in the past have the following numbers.
First, pentafluorobenzene is used as the starting material. Pentafluorobenzene first reacts with cyanide reagents such as cuprous cyanide in a specific solvent such as N, N-dimethylformamide (DMF). This reaction must be carried out in an inert gas atmosphere, because reagents such as cuprous cyanide are easy to interact with oxygen and other substances in the air. The heating temperature is generally between 150 and 200 ° C. After several hours of reaction, the bromine atom of pentafluorobenzene is replaced by a cyanyl group, and cyanopentafluorobenzene can be obtained. After the reaction is completed, a relatively pure product can be obtained by extraction, distillation and other purification methods.
Second, pentafluorobenzoic acid is used as the starting material. First, pentafluorobenzoic acid is reacted with dichlorosulfoxide to convert it into pentafluorobenzoyl chloride. This reaction is relatively mild and can proceed smoothly at room temperature or under slightly heated conditions. Pentafluorobenzoyl chloride reacts with ammonia to form pentafluorobenzamide. Subsequently, pentafluorobenzamide is dehydrated by heating under the action of a dehydrating agent such as phosphorus pentoxide to obtain cyanopentafluorobenzene. Although there are many steps in this path, the reaction conditions of each step are easier to control, and the purity of the
Third, pentafluorophenylboronic acid is used as the starting material. The pentafluorophenylboronic acid reacts with cyanylation reagents such as trimethylsilyl cyanide (TMSCN) in a suitable solvent under the action of transition metal catalysts such as palladium catalysts. This reaction condition is relatively mild and usually occurs at room temperature or slightly higher. The palladium catalyst can promote the substitution of boron atoms on the cyano-p-phenyl ring. After subsequent treatment, cyanopentafluorobenzene can also be prepared.
The above preparation methods have their own advantages and disadvantages. When implementing, it needs to be carefully selected according to the availability of raw materials, cost, product purity requirements and many other factors.
What Cyanopentafluorobenzene need to pay attention to when storing and transporting
Cyanopentafluorobenzene is a chemical substance. When storing and transporting cyanopentafluorobenzene, you must exercise caution and strictly abide by all the rules.
First of all, when storing cyanopentafluorobenzene, it has certain chemical activity and potential danger, and must be stored in a cool and ventilated warehouse. Due to excessive temperature or changes in its chemical properties, it is dangerous. The temperature of the warehouse should be controlled within a specific range to prevent deterioration. And it should be kept away from fire and heat sources, which can easily cause it to burn or explode.
Furthermore, it should be stored separately from oxidizing agents, reducing agents, acids, bases, etc., and must not be mixed. Cover because it encounters with various types of chemicals, or causes violent chemical reactions, causing disasters. The storage place also needs to be equipped with suitable materials to contain the leakage. Once there is a leak, it can be disposed of in time to avoid its spread and cause greater harm.
As for transportation, cyanopentafluorobenzene must be transported according to the regulations of hazardous chemicals. The transportation vehicle should be equipped with the corresponding variety and quantity of fire-fighting equipment and leakage emergency treatment equipment. During driving, drivers and escorts must pay close attention and must not stop at will to prevent accidents. The trough (tank) car used during transportation should have a grounding chain, and holes can be set in the trough to reduce static electricity generated by shock. When loading and unloading, the operation should be light and light, and it is strictly forbidden to drop, heavy pressure and friction to avoid material leakage caused by damage to the container. Overall, the storage and transportation of cyanopentafluorobenzene must be carried out in accordance with regulations to ensure safety.