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Bromo Fluorobenzene

Bromo Fluorobenzene

Hongda Chemical

Specifications

HS Code

754455

Chemical Formula C6H4BrF
Molar Mass 175.00 g/mol
Appearance Colorless to light yellow liquid
Odor Characteristic aromatic odor
Density 1.57 g/cm³ (approximate)
Boiling Point 155 - 157 °C
Melting Point -36 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Flash Point 49 °C (closed cup)

As an accredited Bromo Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of Bromo fluorobenzene packaged in a tightly - sealed glass bottle.
Storage Bromo fluorobenzene should be stored in a cool, well - ventilated area, away from heat sources and open flames as it is flammable. Keep it in a tightly sealed container to prevent vapors from escaping. Store it separately from oxidizing agents and incompatible substances. Ensure storage facilities comply with safety regulations to avoid potential chemical reactions and hazards.
Shipping Bromo fluorobenzene is shipped in specialized, well - sealed containers to prevent leakage. It adheres to strict hazardous chemical shipping regulations, ensuring safe transport due to its potentially harmful nature.
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Bromo Fluorobenzene Bromo Fluorobenzene
General Information
Historical Development
Bromofluorobenzene is also an organic chemical. At the beginning, chemists dedicated themselves to exploring new substances, and after various experiments, they obtained this quality. At the beginning, the preparation was difficult, and the amount produced was small, and it was only used for less research.
Over time, technology has advanced, and the preparation method has improved. The reaction conditions are gradually easier to control, and the yield has also increased. Since the micro-test in the laboratory, as for the mass production of industry, bromofluorobenzene has become more and more widely used.
In the field of medicine, it is used to make special drugs and treat various diseases; in the material industry, it is used to make new materials with specific properties. Looking at the path of its development, from rare research materials to widely used products, it all depends on the unremitting research and technological innovation of scientists, which has caused the prosperity of bromofluorobenzene today.
Product Overview
"Bromofluorobenzene Product Overview"
Bromofluorobenzene is an important compound in organic chemistry. Its unique structure is composed of bromine atoms and fluorine atoms on the benzene ring. This compound is widely used in the field of organic synthesis.
In pharmaceutical research and development, bromofluorobenzene is often a key intermediate. Due to its special chemical properties, it can participate in many reactions, helping to build complex drug molecular structures and help create new special drugs.
In the field of materials science, it also has outstanding performance. With its unique electronic properties and stability, it can be used to prepare polymer materials with special properties, or to optimize the electrical and optical properties of materials.
The synthesis method of bromofluorobenzene has undergone unremitting exploration by researchers and has several mature paths. However, in order to improve the yield and optimize the purity, it still needs to be continuously studied. In short, bromofluorobenzene plays a significant role in many fields of modern chemistry, and the future research prospects are broad.
Physical & Chemical Properties
Bromo Fluorobenzene has its own unique physical and chemical properties. Its shape may be liquid at room temperature, colored or clear and transparent, with a certain volatility. Looking at its boiling point, it is in a specific temperature range, which depends on the strength of the intermolecular forces. Its density is different from that of water, whether light or heavy, and is closely related to the molecular structure.
In terms of chemical properties, the presence of benzene rings gives it aromatic properties and can participate in a variety of electrophilic substitution reactions. The atoms of bromine and fluorine, due to the difference in electronegativity, affect the distribution of the electron cloud of the molecule, so that the compound exhibits unique activity in chemical reactions. Bromine atoms can be replaced by nucleophiles under suitable conditions. Although fluorine atoms are relatively stable, they can also participate in reactions in specific environments due to their physical and chemical interactions.
Technical Specifications & Labeling
The master of Bromo Fluorobenzene is also a thing of transformation. The quality of the technology of its creation is essential. The extraction of its materials, the quality of the material, and the quality of the product, can only be achieved well. The quality of the work, the quality and the strength of the product need to be controlled. The high speed of the product, or the speed of the production; the low speed of the product, the speed of the reaction, and the effect. The same is true of the force, and the appropriate degree should be used.
As for the quality of the product, it must be clear and clear. The business information of its name, price, date of production, batch, etc. is clear one by one. So that users can know its characteristics at a glance, so that they can use it with peace of mind. In this way, the quality of the technology is appropriate, and the products of Bromo Fluorobenzene can be guaranteed, and their effectiveness can be used for general purposes.
Preparation Method
To prepare bromofluorobenzene, the raw materials and production process are the key. First take an appropriate amount of fluorobenzene as the base material and use bromine as the reactant. During the reaction, the temperature needs to be controlled in a moderate range. You can use the method of water bath or oil bath to steadily heat up and make the reaction smooth.
The reaction steps are as follows: First place the fluorobenzene in a clean reactor, slowly inject the bromine solution, and add an appropriate amount of catalyst to promote the efficient progress of the reaction. During the reaction, continue to stir to fully mix the materials. After the reaction is completed, the product is purified through distillation, extraction and other processes.
In this process, monitoring and regulation mechanisms are very important. Pay close attention to the changes in reaction temperature and pressure, and fine-tune the reaction conditions based on real-time data to ensure that the reaction advances in the expected direction, so that high-quality bromofluorobenzene can be prepared.
Chemical Reactions & Modifications
Bromo Fluorobenzene is an organic compound. Its chemical reaction and modification are particularly important in the academic community.
Looking at its reaction, the way of nucleophilic substitution can make the halogen replaced by other groups. When encountering strong bases, it may generate elimination reactions and form an unsaturated structure. Under light or heating, there are also unique changes.
As for modification, the introduction of functional groups can adjust its physical and chemical properties. Or increase its ability to dissolve, or change its reaction activity. By modifying the benzene ring, the field of its application can be expanded. For example, in the production of medicine or the research of materials, it is expected to develop its talents. To explore its depth, it is necessary for colleagues to study it diligently in order to understand its mysteries and make good use of it.
Synonyms & Product Names
Today there is a thing called Bromo Fluorobenzene, which is a chemical product. Its synonymous name and the name of the commodity are worth studying.
In the field of chemistry, this thing may have another name, all of which exist due to the difference in academic inquiry and technological application. Its synonymous name is covered by the sages in the industry, according to its chemical nature and structure. Or due to the reaction mechanism, or the composition of the material, a variety of titles have arisen, all of which are intended to accurately express their characteristics.
As for the name of the commodity, it is related to market circulation and industrial application. In order to recognize its characteristics, attract the attention of customers, or give it a unique name according to its purpose and quality. In this way, in the field of chemical trading, with this trade name, everyone knows its general meaning.
In summary, although the synonyms and trade names of Bromo Fluorobenzene are different, they all revolve around the essence of this chemical and have their own uses. They are both important in chemical research and industrial practice.
Safety & Operational Standards
Safety and Operation Specifications for Bromofluorobenzene
Bromofluorobenzene is also a commonly used substance in chemical research. In all aspects of its experimental operation and storage, it is necessary to strictly abide by safety and operation standards to ensure that everything goes smoothly and is not at risk.
#1. Storage Rules
Bromofluorobenzene should be stored in a cool, dry and well-ventilated place. Keep away from fires and heat sources to prevent accidents. Because of its certain chemical activity, if it is heated or exposed to open flames, it is afraid of violent reactions. In the storage place, the temperature should be controlled within a suitable range, not too high, so as not to cause its volatilization to intensify or cause other chemical changes. And should be placed separately from oxidizing agents, acids, alkalis and other substances, because bromofluorobenzene is prone to chemical reactions with these substances, and mixed storage increases the risk of danger. In the warehouse, when there are suitable equipment to contain leaks, in case of leakage, it can be dealt with in time to prevent its spread and cause disaster.
#2. Qualified operation
Operators must be professionally trained and familiar with the characteristics of bromofluorobenzene and related operating procedures before performing this work. When operating, wear protective clothing, protective gloves and goggles in front of appropriate protective clothing to protect your own safety. Operate in the fume hood to ensure air circulation, so that the volatile bromofluorobenzene can be discharged in time, so as not to cause the operator to inhale too much and damage health. When taking bromofluorobenzene, the action should be steady and accurate, and do not spill it. If it is accidentally spilled, it should be cleaned up immediately according to the established method. After use, properly seal it, and check whether the storage container is well sealed to prevent leakage.
All work involving bromofluorobenzene should be safety-first, and act in accordance with the above safety and operation norms, so as to avoid disasters, ensure the smooth operation of the experiment, and protect the safety of the personnel.
Application Area
"The Use of Bromofluorobenzene"
Bromofluorobenzene is also a chemical product. It is widely used in the field of medicine and can be used as a raw material for synthetic pharmaceuticals. With its special structure, it can help make a variety of special drugs, treat various diseases, and save people's suffering.
In the realm of materials, it can be used to make special materials and increase their properties. If the material has better stability and corrosion resistance, it can be used in equipment and fixtures for durability.
It is also used in scientific research experiments and is a commonly used reagent. Scientists rely on the characteristics of its reaction with other substances to explore the secrets of chemistry, study the laws of material change, and promote academic progress. It can be seen that bromofluorobenzene plays a pivotal role in many application fields such as medicine, materials, and scientific research, and contributes greatly to the development of chemistry and the well-being of mankind.
Research & Development
Taste the wonders of chemistry, it is related to the change of all things. Today, Bromo Fluorobenzene has been studied by our generation for a long time.
When I first came into contact with this product, I felt that its structure is exquisite and its properties are unique. After months of investigation, I have achieved a lot in the synthesis method. First, I started with a certain method, and then added various reagents to control temperature and pressure, and then obtained this product. However, at the beginning, the yield did not meet expectations, and I was worried.
After repeated speculation, I carefully observed the slight changes in each step and adjusted the strategy. Or the amount of reagent is easier, or the reaction time is longer, and finally the yield gradually increases, and the quality is also good.
Looking to the future, we hope to expand its use based on this. Or used in medicine to cure various diseases; or applied to materials to increase their properties. We will continue to study, so that Bromo Fluorobenzene can shine in many fields and contribute to the development of chemistry.
Toxicity Research
Bromofluorobenzene is also a chemical product. In toxicity studies, it is quite important.
Today's detailed investigation of this product, its molecular structure is unique, and the juxtaposition of bromine and fluorine atoms may lead to special chemical properties. Looking at its performance in various experiments, the effect on organisms cannot be underestimated.
Taste a white rat as a test, administered bromofluorobenzene, and it was seen that its physiological function may have abnormalities. The detection of its liver and kidney function, the indicators may be abnormal. And in the observation of neurobehavior, the activities and reactions of the mice also showed abnormal signs.
In addition to its environmental toxicity, in aquatic ecosystems, it can cause the growth of plankton to be hindered, and the balance or destruction of the population.
In summary, the toxicity of bromofluorobenzene is potentially dangerous to individual organisms and the ecological environment. Follow-up research should delve into its toxicological mechanism in order to ensure the foundation of prevention and control, preserve the safety of life and the environment.
Future Prospects
Bromo Fluorobenzene is a transformative thing. I have researched it, and I hope it will be developed in the future. Its characteristics are not unique, or it can be used in many new domains.
In the future, I hope that with this material base, there will be a new way. Such as the field of, or it can be used to make special effects, saving the world. In the world of materials, or by virtue of its properties, we can develop new materials, which are solid and durable.
Furthermore, the method of synthesis can also be refined. Make the efficiency higher and the energy consumption lower, which is in line with the way of colorization. In this way, Bromo Fluorobenzene will definitely be able to be used in the future, and it will be used in the world to make people happy.
Where to Buy Bromo Fluorobenzene in China?
As a trusted Bromo Fluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading Bromo Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of Bromo Fluorobenzene?
Bromofluorobenzene, as well as organic compounds, has a wide range of uses. In the field of chemical industry, it is often used as a raw material for the synthesis of other organic compounds. In its molecular structure, the atoms of bromine and fluorine endow it with unique chemical properties, which can be obtained through various chemical reactions.
In the process of organic synthesis, bromofluorobenzene can participate in nucleophilic substitution reactions. Because its bromine atom has a certain activity, it can be replaced by other nucleophilic reagents, thereby forming new carbon-heteroatom bonds to prepare various fluorine-containing and bromine-containing functional molecules, which have important applications in pharmaceutical chemistry, materials science, etc.
In the field of drug research and development, bromofluorobenzene derivatives exhibit unique biological activities. Some derivatives may have antibacterial, antiviral, antitumor and other pharmacological activities, providing the possibility for the creation of new drugs. The fluorine atoms in its structure can change the lipophilicity, metabolic stability and interaction with biological targets of compounds, enhancing drug efficacy.
In the field of materials science, polymers or organic materials synthesized from bromofluorobenzene often have special physical properties. For example, fluoropolymers often have excellent chemical resistance, low surface energy and good thermal stability, and can be used to manufacture high-performance coatings, plastics and electronic materials.
Furthermore, bromofluorobenzene also plays an important role in the catalytic reaction of organometallic metals. It can form specific complexes with metal catalysts, and then realize some organic synthesis reactions with high selectivity and mild conditions, which promotes the development of organic synthesis chemistry.
In short, bromofluorobenzene plays an important role in many fields such as chemical industry, medicine, materials, etc., and is an indispensable basic compound for modern chemical industry and scientific research.
What are the physical properties of Bromo Fluorobenzene?
Bromofluorobenzene is also an organic compound. Its physical properties are particularly important and are key to many applications.
Bromofluorobenzene is mostly liquid at room temperature, with a special smell, slightly pungent, and can be identified by the sense of smell. Its boiling point is determined by the influence of bromine and fluorine atoms in the molecular structure, and usually boils in a specific temperature range. The characteristics of this boiling point are significantly useful in operations such as separation and purification. Looking at its appearance, it may be a colorless and transparent liquid, clear like glass, shining under light, without turbidity.
In terms of density, due to the relatively large atomic masses of bromine and fluorine atoms, its density is higher than that of common organic solvents. This density characteristic, in the mixed system, can make bromofluorobenzene present a specific position in the phenomenon of stratification and other phenomena, which is easy to identify and operate. In terms of solubility, bromofluorobenzene has good solubility in organic solvents such as ethanol and ether. However, in water, because it is a non-polar or weakly polar molecule, it is difficult to dissolve because of its large polarity difference from water. This difference in solubility is very useful in the process of extraction, reaction medium selection, etc. The vapor pressure of
bromofluorobenzene also has its value at a certain temperature, which is related to the difficulty of volatilization. Because its steam has a certain pressure, in a confined space or under specific conditions, the volatilization situation needs to be carefully considered to prevent potential safety hazards. In addition, the refractive index of bromofluorobenzene is also one of its important physical properties. The refractive index reflects the degree of change in the direction of light propagation in it, and can be an important indicator in the fields of optical related research and quality inspection.
What is the chemistry of Bromo Fluorobenzene?
Bromofluorobenzene is a genus of organic compounds. Its properties are in the chemical environment and are quite specific. Bromine and fluorine atoms are attached to the benzene ring, resulting in different chemical properties from benzene.
In terms of reactivity, bromine atoms have a tendency to nucleophilic substitution. Because the electronegativity of bromine atoms is slightly higher than that of carbon, the carbon-bromine bond electron cloud is biased towards bromine, which makes the carbon band partially positively charged and easy to be attacked by nucleophilic reagents. When the nucleophilic reagents approach, the carbon-bromine bond breaks, new bonds are formed, and substitution products are formed.
Although the fluorine atom is extremely electronegative, the density distribution of the electron cloud in the benzene ring changes due to the small radius of the fluorine atom This effect has a dual effect on the activity of the benzene ring: on the one hand, the electron-withdrawing induction effect of fluorine atoms reduces the electron cloud density of the benzene ring, and it is more difficult to cause electrophilic substitution than benzene; on the other hand, the electron-giving conjugation effect affects the reactivity at specific positions.
In electrophilic substitution, the activity of bromofluorobenzene is slightly reduced due to the electron-withdrawing effect of fluorine and bromine. However, the activity of different positions on the benzene ring is different. The adjacent and para-sites are affected by the conjugation effect, and the electron cloud density is relatively high, and the electrophilic reagents are easy to attack these two sites.
Another bromofluorobenzene can be involved in many reactions, such as metal catalytic coupling reactions In such reactions, bromine or fluorine atoms can interact with metal reagents, and through complex mechanisms, they can be connected with other organic fragments to form complex compounds, which are widely used in the field of organic synthesis.
The complexity and diversity of its chemical properties stem from the interaction between bromine and fluorine atoms and benzene rings. These characteristics make bromofluorobenzene important in the fields of organic chemistry research and industrial production.
What are the production methods of Bromo Fluorobenzene?
Bromofluorobenzene is also an organic compound. The preparation method is quite complicated. The following numbers are listed:
First, the halogen exchange method. Starting with halobenzene, it is used to react with metal fluorides, such as potassium fluoride, in a specific solvent with an appropriate catalyst. During this process, halogen atoms are exchanged with each other to obtain bromofluorobenzene. The solvent used is often a polar aprotic solvent such as dimethyl sulfoxide, which can increase the solubility of metal fluorides and promote the reaction. The catalyst is selected as a crown ether, which can complex with metal ions and enhance the activity of fluoride ions.
Second, the diazonium salt method. The diazonium salt is first prepared from aniline, and then interacts with cuprous bromide and hydrogen fluoride. Aniline is reacted by diazotization to form diazonium salt, which is an active intermediate. In case of cuprous bromide and hydrogen fluoride, the diazonium group is replaced by bromine and fluorine to obtain bromofluorobenzene. This process requires temperature control, and the diazotization reaction should be at a low temperature. The subsequent substitution reaction is adjusted according to the actual situation.
Third, the direct halogenation method. Using benzene as the raw material, a suitable halogenating agent is selected, such as bromine and a fluorinated halogenating agent, and the reaction is carried out in the presence of a catalyst. Catalysts commonly use Lewis acids, such as aluminum trichloride. The electron cloud density of the benz However, the selectivity of this reaction needs to be fine-tuned, because the high activity of the benzene ring is easy to cause the formation of polyhalogenated products.
When preparing bromofluorobenzene, each method has its advantages and disadvantages. Depending on the availability of raw materials, cost, product purity and other factors, careful selection and fine control of the reaction conditions can obtain satisfactory results.
What are the precautions for storing and transporting Bromo Fluorobenzene?
Bromofluorobenzene is also an organic compound. During storage and transportation, all kinds of precautions are of paramount importance.
First of all, when storing, find a cool and ventilated warehouse. This bromofluorobenzene is prone to danger due to heat, and a cool place can reduce its risk. The temperature of the warehouse should be properly controlled and not too high to prevent its properties from changing. And it needs to be kept away from fire and heat sources. Fire and heat sources can cause it to explode, endangering safety.
Furthermore, bromofluorobenzene should be stored in separate stores with oxidants and edible chemicals. Oxidants are highly oxidizing and coexist with bromofluorobenzene, or cause severe chemical reactions; and mixed with edible chemicals, in case of leakage, contaminate food, and cause endless harm.
As for transportation, there are also many details. Transportation vehicles should ensure that they are in good condition and equipped with corresponding fire equipment to deal with sudden fire risks. When loading, they must be lightly loaded and unloaded, and must not be operated brutally to avoid leakage of bromofluorobenzene due to damaged packaging. During transportation, drivers should be careful to prevent exposure to the sun, rain, and avoid high temperatures. In case of high temperature weather, it is advisable to travel in the morning and evening to avoid the extreme heat during the day.
The escort personnel should not be slack, and they should be familiar with the characteristics of bromofluorobenzene and emergency response methods. In case of leakage, they can be properly disposed of quickly to avoid major disasters. In this way, when storing and transporting bromofluorobenzene, pay attention everywhere, and be careful in everything, so that the security will be safe.