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Benzenethiol, 2,5-Difluoro-

Benzenethiol, 2,5-Difluoro-

Hongda Chemical

Specifications

HS Code

435300

Chemical Formula C6H4F2S
Molecular Weight 146.16
Odor Thiol - like odor (expected)
Solubility In Water Low solubility (expected for thiol with aromatic ring)
Solubility In Organic Solvents Soluble in common organic solvents (e.g., ethanol, acetone, etc.)
Stability Stable under normal conditions but may react with strong oxidizing agents

As an accredited Benzenethiol, 2,5-Difluoro- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 2,5 - difluorobenzenethiol in a sealed, chemical - resistant bottle.
Storage Store "2,5 - difluorobenzenethiol" in a cool, dry, well - ventilated area away from heat sources and open flames. It should be kept in a tightly sealed container to prevent vapor leakage. Due to its potential reactivity, store it separately from oxidizing agents and strong bases. Avoid storing in areas prone to high humidity to prevent hydrolysis.
Shipping Benzenethiol, 2,5 - difluoro - is shipped in accordance with strict chemical transportation regulations. It is packaged securely in appropriate containers to prevent leakage, and transported by approved carriers ensuring safe delivery.
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Benzenethiol, 2,5-Difluoro- Benzenethiol, 2,5-Difluoro-
General Information
Historical Development
I have heard that the name of the object is "Benzenethiol, 2,5 - Difluoro -". The beginning of the object originated from the research of the sages. At the beginning, everyone did not know its nature, but they were diligent in exploring it. As the years passed, each family changed and changed, and each family showed their talents. They have all entered the art of chemical theory and craftsmanship. At the beginning, they knew its shape and quality roughly, and then they carefully observed its changes and understood the wonders of its application. The researchers worked tirelessly, and their structure and nature became more and more clear. After years of study, it gradually became clear that it was used in various karma, or for medicine, or to assist in craftsmanship, and the involved became more and more extensive. From the beginning of the ignorance, today's familiarity, all rely on the work of the sages over the years, to get this "Benzenethiol, 2,5 - Difluoro -" evolution, add luster to Xuelin, for future generations.
Product Overview
There is a substance today called Benzenethiol (2,5 - Difluoro -). This substance is an organic compound. In its molecular structure, the fluorine atom at the second and fifth positions on the benzene ring is attached, and the thiol group is also connected to the benzene ring.
Looking at its physical properties, it may be a colorless to light yellow liquid at room temperature, with a special odor. Its melting point, solubility and other properties are related to the interaction between atoms in the molecule. Because of its fluorine atom, high electronegativity causes the polarity of the molecule to change; the existence of thiol groups makes this substance have specific chemical activities. In chemical reactions, the fluorine atoms of this compound can be replaced by nucleophilic substitution and other reactions, and thiol groups can also participate in many reactions such as oxidation and condensation. In the field of organic synthesis, they can also be used as key intermediates to assist in the construction of many complex organic molecules.
Physical & Chemical Properties
"On the Physical and Chemical Properties of Difluoro-2,5-phenylthiophenol"
Fudifluoro-2,5-phenylthiophenol is an important substance for chemical research. Its physical properties, at room temperature, are either liquid, unique in color, colorless and clear, or slightly colored, but they all change according to environmental conditions. Looking at its appearance, texture or uniform fluid, the fluidity is also considerable.
In terms of its chemical properties, thiophenol groups are highly active and easily react with many substances. Due to the introduction of fluorine atoms, the distribution of electron clouds changes, resulting in its reaction activity being very different from that of ordinary thiophenol. Or under specific conditions, it can interact with electrophilic reagents and nucleophiles to form new compounds.
And this substance may have important uses in the field of organic synthesis, and can be used as an intermediate to help synthesize complex organic molecules. The study of its physicochemical properties is of far-reaching significance in many fields such as chemical industry and materials science, which can inspire new research directions and contribute to scientific and technological progress.
Technical Specifications & Labeling
Today there is a product called "Benzenethiol, 2,5 - Difluoro -". To clarify its technical specifications and labels (product parameters), we need to explore in detail.
When looking at this substance, the first thing to do is to observe its properties, color, odor, and morphology. Then measure its purity, and the exact value depends on the quality. Its physical properties, such as melting point, boiling point, density, etc., cannot be ignored, which is the basis for identification.
In terms of chemical properties, the reactivity and stability need to be carefully investigated. Reactions with common reagents should be recorded. On the label, the name must be accurate, and the molecular formula and structural formula must be clearly presented. In the product parameters, the content, impurity limit, etc. are clearly marked to make it clear to everyone at a glance. Only by following this specification can we ensure the quality and application of this product are correct.
Preparation Method
Preparation of difluorothiophenol
To prepare 2,5-difluorothiophenol (Benzenethiol, 2,5-Difluoro-), the selection of raw materials is very important. When fluoroaromatic hydrocarbons are used as starting materials, the aromatic hydrocarbons need to have suitable substituents for subsequent reactions to carry out.
In the preparation process, the first step can make fluoroaromatic hydrocarbons react with sulfur sources under specific conditions. The sulfur source is often sodium sulfide or sodium hydride. The reaction is carried out in a solvent, such as DMF or DMSO, which can improve the solubility and reactivity of the raw materials. Control the reaction temperature in a moderate range, such as 80-120 degrees Celsius, and continue to stir for several hours to make the reaction sufficient.
Then proceed to the subsequent conversion step. The obtained intermediate product is acidified to adjust the pH value to the acidic range and promote the free release of the target product. At this time, the product may precipitate in an oily state.
When separating and purifying, use extraction, distillation and other means. The product is extracted with an organic solvent, and then the solvent and unreacted raw materials are removed by distillation to obtain pure 2,5-difluorothiophenol. The key to this preparation method is precise control of the raw materials and proper regulation of the conditions of each reaction step to ensure the yield and purity of the product.
Chemical Reactions & Modifications
Today there is a chemical substance called Benzenethiol, 2,5 - Difluoro -. In my pursuit of chemistry, the chemical reaction and modification of this substance are of paramount importance.
To observe its reaction, it is necessary to use a precise method to control its conditions and make the reaction go smoothly. Temperature, pressure, catalyst and other factors are all related to the success or failure of the reaction. Either adjust the temperature to make the molecular activity change and the reaction rate appropriate; or choose an appropriate catalyst to reduce the energy barrier of the reaction and promote its efficient transformation.
As for modification, we want to add new substances to meet the needs of diversity. Specific groups can be introduced to change their chemical and physical properties. Through these various research and development, we hope to obtain products with excellent performance, which can be used in various fields such as chemical industry and medicine, and can be used by the world.
Synonyms & Product Names
I heard that there is a thing called Benzenethiol, 2,5-Difluorothiophenol (Benzenethiol, 2,5-Difluoro-), which is quite useful in our chemical research. The nickname and trade name of this thing are also the key to the research.
The nickname of the husband is chosen by colleagues in the academic community for the convenience of research and the observation of characteristics. Although the name of the product refers to the same, the use may be different from the situation involved. The nickname mostly exists between academic discussions and experimental records, and everyone uses it to accurately express and clarify the object under investigation. Trade names are often used in business transactions, and merchants are designed to recognize their characteristics and facilitate their promotion.
To study this 2,5-difluorothiophenol, we need to carefully investigate its nickname and trade name in order to be able to enjoy academic exchanges and industrial applications without hindrance, accurately grasp its role and value in various fields, and then promote the progress of chemical research and expand the scope of its practical application.
Safety & Operational Standards
About 2,5-difluorothiophenol product safety and operating specifications
Fu 2,5-difluorothiophenol is an important product in chemical research. When it is used in experiments and operations, safety should be the first thing to pay attention to.
This product has certain toxicity and irritation. If it accidentally touches the skin, rinse with a lot of water as soon as possible, and it needs to be rinsed continuously for a long time to keep it clean. If it enters the eye, it is necessary to open the eyelids immediately, rinse with water or normal saline, and seek medical treatment as soon as possible without a slight delay.
In the operating environment, it is necessary to ensure good ventilation. It is suitable for use in fume hoods to prevent their volatile gases from accumulating in the room, causing deterioration of air quality and endangering people. The utensils used should also be clean, dry, and suitable for the characteristics of the chemical to avoid chemical reactions and accidental changes.
In addition, there are rules for storage. When placed in a cool, dry and ventilated place, away from fires and heat sources. Do not store with oxidants, acids, etc., to prevent dangerous chemical changes from contact. The container must be tightly closed to prevent its volatilization from leaking.
When using, it is necessary to take the utensils according to the precise quantity and standard operation procedures. Do not touch with bare hands, must use suitable tools. When weighing, it is necessary to be precise, not only to avoid waste of materials, but also to prevent danger due to improper quantity.
In short, the safety and operation specifications of 2,5-difluorothiophenol, all the details are related to personal safety and the success or failure of the experiment. It must not be slack, and it must be followed carefully to ensure that everything goes smoothly and there is no disaster.
Application Area
Today there is a product called Benzenethiol, 2,5 - Difluoro -. This product has its uses in many fields. In the field of medicine, it may be used to develop new drugs with its unique properties to cure various diseases and help patients recover. In the field of materials, it may contribute to the development of materials with specific properties, so that materials have better characteristics, such as enhancing their stability and flexibility. Also in chemical synthesis, it can be used as a key raw material or auxiliary agent to help synthesize complex and delicate compounds and promote the progress of the chemical industry. It has a wide range of uses and can play an important role in many practical fields, contributing its unique power to the development of various industries.
Research & Development
Taste the way of scientific research, the most important thing is to be diligent. Today, I study a thing, and it is called "Benzenethiol, 2,5 - Difluoro -". I am in this thing, and I think hard and explore its nature.
Initial observation of its shape and quality, examination of its structure, as if seeking seclusion and mystery, step by step. Then study its reaction rules, and under various conditions, observe the wonders of its changes. Or the rise and fall of temperature, or the increase and decrease of the agent, all of which are carefully investigated and carefully observed.
During this period, there are countless obstacles, but my resolve remains firm. Every gain is like a treasure. After months of study, I gradually understand its characteristics, and I also know the way to apply it.
I believe that with time and unremitting progress, this "Benzenethiol, 2,5 - Difluoro -" will surely be able to shine in the field of scientific research, contribute to academic progress, achieve a career, and live up to the heart of research.
Toxicity Research
The study of toxicology is related to the health of people's livelihood, and the toxicity of things cannot be ignored. There are chemical substances today, called Benzenethiol, 2,5 - Difluoro -, and the study of its toxicity is crucial.
To understand its toxicity, it is necessary to explore its behavior and observe its response to other things. Examine the path of its entry into the body, or through the mouth and nose, or through the skin. After entering the body, observe its changes in the meridians of the organs, whether it disturbs the transportation of qi and blood, and disrupts the balance of yin and yang.
It is also necessary to study its shadow in the environment. If it is scattered in the sky and earth, can it cause pollution of water, soil and air? Is it harmful to living things? Although this research is still difficult, it is related to the well-being of all living beings. We must make every effort to investigate the toxicity of Benzenethiol, 2,5 - Difluoro - as the basis for protection and governance, and to ensure the safety of life in the world.
Future Prospects
I try to research new chemical products, Benzenethiol, 2,5 - Difluoro - this product is also. Looking at its characteristics, it has novelty and seems to hide endless potential. Although what I know today is limited, I think about the future and look forward to it.
I imagine that in the future, I may develop my talents in the field of medicine. With its unique structure, it may be able to make special drugs to solve the pain of everyone. Or in the world of materials, it can shine brightly, help new materials come out, strengthen the performance of equipment, and benefit all things in life.
I firmly believe that with time and dedicated research, I will be able to explore its mysteries and make it useful to the world. At that time, this product will definitely be able to explore a new world in the unknown, become the cornerstone of future development, and fulfill our unfulfilled ambitions.
Where to Buy Benzenethiol, 2,5-Difluoro- in China?
As a trusted Benzenethiol, 2,5-Difluoro- manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading Benzenethiol, 2,5-Difluoro- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of Benzenethiol, 2,5-Difluoro-?
2% 2C5 -difluorothiophenol, this material has unique chemical properties. Its properties are mostly colorless to light yellow liquid with pungent odor.
In terms of chemical activity, due to the fluorine atom and thiol group connected to the benzene ring, the fluorine atom has strong electronegativity, causing the electron cloud density of the benzene ring to change, resulting in uneven distribution of the electron cloud of the molecule. Mercapto (-SH) has high activity and is prone to oxidation reactions. It can be slowly oxidized to disulfide in air. And because of its acidic hydrogen, it can react with bases to form corresponding salts.
It is active in nucleophilic substitution reactions. The fluorine atom on the benzene ring can be used as a leaving group and replaced by other nucleophilic reagents. When conditions are suitable, it can efficiently construct new carbon-heteroatom bonds, which can be used in the field of organic synthesis to prepare a variety of complex compounds containing sulfur and fluorine substitution. At the same time, it can participate in the coupling reaction catalyzed by transition metals, couple with halogenated aromatics or olefins, expand the molecular structure, and has a wide range of uses in pharmaceutical chemistry, materials science, etc. It can provide key intermediates for the development of new drugs and functional materials.
What are the main uses of Benzenethiol, 2,5-Difluoro-
Phenylthiophenol, 2,5-difluoro - This substance has a wide range of uses. In the field of medicinal chemistry, it is often a key raw material for the synthesis of specific drugs. Due to its unique chemical structure, it can precisely interact with specific targets in organisms, helping to develop innovative drugs for difficult diseases, such as anti-tumor and antiviral drugs.
In the field of materials science, it also plays an important role. It can be chemically modified to prepare functional materials with special properties, such as materials with unique regulation of electron transmission and optical properties. It is used in organic semiconductors, optoelectronic devices and other fields to improve device performance and stability.
In the field of organic synthesis, it can be called an important organic synthesis intermediate. With its active functional groups, it can participate in many organic reactions, realize the construction of complex organic compounds, provide an effective way for the synthesis of new organic molecules, and expand the variety and application range of organic compounds.
In the fine chemical industry, it is often used to prepare high value-added fine chemicals, such as special fragrances, additives, etc. To give products unique aroma or specific properties, to meet the diverse needs of different industries and consumers. In short, thiophenol, 2,5-difluoro-with its special chemical structure and reactivity, plays a key role in many fields, promoting technological progress and innovation development in various industries.
What is the synthesis method of Benzenethiol, 2,5-Difluoro-?
There are currently methods for preparing 2,5-difluorobenzene thiophenol, which are described below.
First take 2,5-difluorobromobenzene as the starting material, which is the basis of the reaction. It is placed in an anhydrous ether environment with magnesium chips to initiate a Grignard reaction. When magnesium chips encounter 2,5-difluorobromobenzene, in case of a good opportunity, the two interact to form 2,5-difluorobenzene magnesium bromide. In this step of the reaction, attention should be paid to the anhydrous environment, because water can disrupt the order of the reaction and cause the reaction to fail to meet expectations.
After obtaining 2,5-difluorobenzene magnesium bromide, carbon disulfide is introduced. Carbon disulfide fuses with 2,5-difluorophenylmagnesium bromide, and the nucleophilic addition reaction occurs between the two. At this time, the molecular structure gradually changes, and the sulfur atom gradually enters the system to construct a new intermediate. This reaction step requires moderate temperature control. If the temperature is not appropriate, the rate and direction of the reaction can change.
The intermediate is obtained, and then it is treated with dilute acid. Under the action of dilute acid, the intermediate is decomposed and converted, and the final product is 2,5-difluorothiophenol. The concentration and dosage of dilute acid are both key. Too high or too low concentration, too much or too little dosage can affect the purity and yield of the product.
There are other methods. It can be started from 2,5-difluoronitrobenzene, and the nitro group is first converted into an amino group through a reduction reaction to obtain 2,5-difluoroaniline. In this reduction process, suitable reducing agents and reaction conditions can be selected to achieve efficient reduction.
2,5-difluoroaniline reacts with thiocyanate to form 2,5-difluorobenzene thiocyanate. Then, 2,5-difluorobenzene thiocyanate is treated with suitable reagents to convert it into 2,5-difluorobenzene thiophenol. This path step is slightly complicated, but if the reaction conditions are properly controlled, satisfactory results can also be obtained.
The method of preparing 2,5-difluorothiophenol, the above two are more common. In actual operation, the optimal method should be selected according to the availability of materials, cost, equipment conditions and other factors.
Benzenethiol, 2,5-Difluoro - what is the price range in the market?
I don't know what the market price range of 2,5-difluorothiophenol is. This compound is not a commonly used compound that I am familiar with, and the market price is easy to change for a variety of reasons.
Or you can explore its price from various ways. First, ask chemical raw material suppliers. Many supplier websites may have quotations, but different suppliers may have different prices due to factors such as product purity, packaging, and purchase volume. Second, look at the chemical product trading platform. This platform gathers the quotations of various merchants and can provide reference for the price range. Third, check industry information and market survey reports. Such resources may contain price analysis of the product in a specific period, but they may be time-sensitive.
Because I do not have the exact market data, it is difficult to specify its price range. If you want to know the exact price, you need to go to the above channels for detailed investigation and integrate multi-channel information to obtain a more accurate market price range of 2,5-difluorothiophenol.
What are the manufacturers of Benzenethiol, 2,5-Difluoro-?
The manufacturer of benzothiophenol, 2,5-difluoro-this substance, has been involved in many industry leaders throughout the ages. In the past, in the field of fine chemicals, there were several well-known factories that dedicated themselves to the manufacture of this product with their exquisite skills and unremitting research.
Among them, there is a factory named [Factory Name 1], which has a long-standing reputation. Since its establishment, it has focused on the research and production of fluorine-containing fine chemicals. The factory has brought together a group of talents, refined chemical technology, and committed to the production of benzothiophenol, 2,5-difluoro-with advanced equipment and rigorous technology. Its products are of high quality, praised in the industry's internal ads, exported to many places, and favored by all merchants.
There is also [factory name 2], which is also a leader in the industry. The factory adheres to the concept of innovation and constantly explores ways to optimize production. It is extremely strict in the selection of raw materials and the control of production processes. With the persistent pursuit of quality, the phenylthiophenol, 2,5-difluoro-, has occupied a place in the market, established solid cooperation with many large enterprises, and made great contributions to the development of the industry.
Looking at the moment, new enterprises have also sprung up like mushrooms after a rain. [ Factory name 3] is one of them. Although it has been established for a short time, it has quickly emerged in the field of phenylthiophenol and 2,5-difluoro-production with its novel technology and flexible operation model. This factory pays attention to the balance of environmental protection and efficiency, and the products produced not only meet the quality standards, but also have remarkable aspects in green production. It is expected to become an important force in the industry in the future.
In summary, the manufacturer of phenylthiophenol and 2,5-difluoro-production has both an established powerhouse that has been precipitated over the years, and a vibrant emerging enterprise. Together, we promote the development and progress of this product.