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Benzenesulfonic Acid, 4-Fluoro-

Benzenesulfonic Acid, 4-Fluoro-

Hongda Chemical

Specifications

HS Code

786482

Chemical Formula C6H5FO3S
Molar Mass 178.165 g/mol
Appearance Solid (usually white or off - white)
Melting Point 145 - 148 °C
Boiling Point Decomposes before boiling
Solubility In Water Soluble
Solubility In Organic Solvents Soluble in polar organic solvents like ethanol
Acidity Pka Around 0.7 (approximate value for benzenesulfonic acid derivatives)

As an accredited Benzenesulfonic Acid, 4-Fluoro- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 4 - fluoro - benzenesulfonic acid packaged in a sealed plastic - lined container.
Storage 4 - Fluorobenzenesulfonic acid should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition sources. It should be kept in a tightly - sealed container to prevent moisture absorption and leakage. Store it separately from incompatible substances like strong oxidizing agents and bases to avoid potential chemical reactions.
Shipping 4 - Fluorobenzenesulfonic acid is shipped in well - sealed, corrosion - resistant containers. These are typically made of materials suitable for handling chemicals. Shipment follows strict safety regulations to prevent spills and ensure safe transportation.
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Benzenesulfonic Acid, 4-Fluoro- Benzenesulfonic Acid, 4-Fluoro-
General Information
Historical Development
The historical evolution of 4-fluorobenzenesulfonic acid is quite significant. In the past, chemists' research on substances gradually came to this. At the beginning, everyone did not know its characteristics and production methods. However, as time went by, various experimental studies were carried out one after another.
The chemical craftsman of the past, with perseverance, gradually understood the method of its synthesis after countless attempts. From the initial ignorance to the ability to more accurately control the preparation process, it was difficult and difficult to describe. And in terms of nature cognition, it also went from shallow to deep. From the beginning, only a few of its properties were known, to the later details of its chemical activity and reaction laws. In this way, 4-fluorobenzenesulfonic acid has gradually emerged in the field of chemistry, paving the way for more related research and applications in the future.
Product Overview
Description of 4-fluorobenzenesulfonic acid
4-fluorobenzenesulfonic acid is one of the organic compounds with considerable research value. Its characteristics are unique, and its appearance is often in a specific form, or in a crystalline state, with pure color. This substance is widely used in the chemical industry.
In terms of reaction characteristics, it has unique activity due to the presence of fluorine atoms. The introduction of fluorine atoms makes the structure of benzenesulfonic acid change, and the chemical properties are also different. In many organic synthesis reactions, 4-fluorobenzenesulfonic acid is often used as a key reagent, participating in various reaction pathways and helping to generate organic products with specific structures.
From the perspective of physical properties, its melting point, boiling point and other parameters are different from similar benzenesulfonic acid derivatives. These properties are affected by the electronegativity of fluorine atoms and are also related to the interaction between molecules. This unique physical property provides a specific basis for its separation, purification and application under different process conditions. The study of 4-fluorobenzenesulfonic acid is of great significance for expanding organic synthesis methods and optimizing chemical processes.
Physical & Chemical Properties
4-Fluorobenzenesulfonic acid, the physical and chemical properties of this substance are very important in the study of chemistry in China. Its appearance is often colorless to slightly yellow liquid, with a certain degree of corrosiveness. Its physical constants such as melting point and boiling point have been accurately determined to provide key data for chemical applications. In terms of chemical properties, 4-fluorobenzenesulfonic acid has unique activity due to its fluorine atoms and sulfonic acid groups. The electronegativity of fluorine atoms changes the distribution of molecular electron clouds and affects its reactivity. Sulfonic acid groups can participate in many chemical reactions, such as esterification, sulfonation, etc. Knowing the physical and chemical properties of this substance helps to optimize related chemical processes and improve product quality, which is of far-reaching significance in the field of fine chemicals.
Technical Specifications & Labeling
For 4-fluorobenzenesulfonic acid, the process specification and identification (product parameters) are the key. This compound is an important corner of organic synthesis. The process specification needs to specify the method of its preparation, such as the ratio of raw materials, the temperature of the reaction, the degree of time, the catalyst, etc. The steps must be carefully observed to prevent mistakes and impurity of the product.
In terms of identification, the product parameters must be accurate, such as the purity geometry, the characteristics, the number of melting points and boiling points, all of which should be detailed. Purity is related to the quality, the characteristics are shown in an intuitive state, and the melting point helps to identify the authenticity. In this way, in the field of chemical industry, 4-fluorobenzenesulfonic acid can be used to its full extent, to maintain its quality and clarify its properties, so as to meet the needs of diversity.
Preparation Method
To prepare 4-fluorobenzene sulfonic acid (Benzenesulfonic Acid, 4-Fluoro-), the method is as follows:
Prepare raw materials, need fluorobenzene, concentrated sulfuric acid, etc. Place fluorobenzene in a reactor and slowly inject concentrated sulfuric acid, which is the beginning of the sulfonation reaction. Control the temperature in a suitable range, about 60 to 80 degrees Celsius, because the temperature is too high or side reactions occur, and if it is too low, the reaction will be slow.
When reacting, stir well to ensure that the reactants are in full contact. When the number of reactions is to be determined, the degree of reaction can be monitored by thin-layer chromatography. After the reaction is completed, pour the product into ice water to stop the reaction and facilitate the precipitation of the product. After that, the product is purified by extraction, separation, distillation and other steps. Appropriate organic solvent is used for extraction, and the separation needs to be carefully operated to ensure clear delamination. Control the temperature and pressure during distillation to obtain pure 4-fluorobenzenesulfonic acid. In this way, qualified products can be obtained.
Chemical Reactions & Modifications
Today there is a thing called 4-fluorobenzenesulfonic acid. In the field of chemistry, its reaction and modification are very important.
4-fluorobenzenesulfonic acid has unique properties. Its participation in the reaction can produce different results depending on the conditions. To change its properties, it is necessary to observe its structure and understand its mechanism.
Observe its reaction, or nucleophilic substitution, or esterification. Every step of the change can be traced. After ingeniously designing the reaction, specific groups can be introduced to change its physical and chemical properties. Such as adjusting its solubility and stability to suit different needs.
When modifying, chemists are dedicated to applying ancient methods and new techniques. It is hoped to obtain the best method to make 4-fluorobenzenesulfonic acid play a greater role in the fields of medicine and materials, shining brightly and contributing to the progress of chemistry.
Synonyms & Product Names
4-Fluorobenzenesulfonic acid is also known as 4-fluorobenzenesulfonic acid. In the industry, it is also known as p-fluorobenzenesulfonic acid. "Right" means relative position, which is based on the relative orientation of the fluorine atom and the sulfonic acid group in its molecular structure.
In the trade name, there are also those who are called this. Although the names of chemical substances are different, they are all referred to as 4-fluorobenzenesulfonic acid. The different names are due to industry habits, regional differences or different research focuses. However, no matter what the name is, it refers to this specific chemical substance. In chemical research and industrial production, it is necessary to clarify the situation of its synonyms to avoid confusion and errors in research or production.
Safety & Operational Standards
4-Fluorobenzenesulfonic acid is an important chemical substance. In experiments and production, its safety and operating standards are of paramount importance.
The first word is safe. This substance has certain chemical activity or irritation. When handling, it is necessary to wear appropriate protective equipment, such as protective clothing, gloves, goggles, etc., to prevent contact and injury to the skin and eyes. If you accidentally touch it, you should immediately rinse it with a lot of water, and in case of severe cases, seek medical treatment. And store it in a cool, dry and well-ventilated place away from fire and heat sources to prevent accidents.
As for the operating specifications, before the experiment, the process should be detailed and familiar with the steps. When taking it, measure it accurately and operate according to the established procedures. Do not change it. During the reaction process, pay close attention to the reaction conditions, such as temperature, pressure and other parameters. If there is a slight abnormality, take countermeasures quickly. After the experiment, properly dispose of the remaining 4-fluorobenzenesulfonic acid and waste, follow the requirements of environmental protection, and do not dispose of it at will to avoid polluting the environment.
In short, in the research and application of 4-fluorobenzenesulfonic acid, strictly abide by safety and operating standards, in order to obtain its benefits and avoid its harm, ensure the smooth operation of the experiment, protect the safety of personnel, and keep the environment clean.
Application Area
Fluorobenzenesulfonic acid is widely used in various fields. In the field of medicine, it can be used as a key intermediate to help synthesize special drugs, to treat various diseases, and a sharp tool for doctors to cure diseases and save people. In the chemical industry, it can be used as a reaction catalyst to promote the smooth progress of many reactions and improve the efficiency of production. In the preparation of materials, it can participate in the synthesis of specific materials, giving materials unique properties, such as better stability or special physical properties. It has a wide range of uses. In today's technological and industrial development, it is like a cornerstone and indispensable. It promotes the continuous progress of various industries and brings many conveniences and innovations to people's lives.
Research & Development
I have been dedicated to the research and development of chemical products for a long time. Recently, I have been focusing on 4-fluorobenzenesulfonic acid. Its properties are related to many chemical processes, and it is also important to me.
After months of research, I have observed its reaction rules, tried different methods, and wanted to understand its quality and use. At the beginning, I encountered many obstacles, but I did not dare to relax. With all kinds of materials, combine them in different orders, and observe their changes.
Now I have a little bit of knowledge. I know how to control the temperature and speed under a certain situation to make the yield excellent. However, the research is endless, and it still needs to be further explored. In the hope of another day, the fruit of this research can be widely used in the industry, promoting its progress, and benefiting everyone.
Toxicity Research
The toxicity of 4-fluorobenzenesulfonic acid is studied in this study. This substance has many applications in the chemical industry. Looking at its structure, fluorine atoms are connected to the benzenesulfonic acid base. Fluoride is active, or the substance has unique toxicity.
According to animal experiments, if ingested orally, it can initially cause digestive system disorders, such as vomiting, diarrhea and other diseases. And long-term micro-exposure may damage the function of the liver and kidney. Because it is metabolized in the body, the liver and kidney need to perform detoxification and excretion. In addition, it is also irritating to the skin and mucous membranes, and can cause redness, swelling and pain when touched.
Furthermore, in the environment, if this substance flows into water, soil, or affects the ecology. Aquatic organisms bear the brunt, or cause their growth and reproduction to be hindered. Therefore, studying its toxicity has significant implications for safe production, environmental protection, and human health.
Future Prospects
The art of chemistry in this world is improving day by day, and there is a thing called 4-fluorobenzenesulfonic acid. Its future prospects cannot be called grand. This material difference, or in the road of medicine, can help research new agents, treat all kinds of chronic diseases, and save people from sinking diseases; in the field of materials, it can be transformed into rare materials, increase its firmness and corrosion resistance, and be used for fortifications. And the characteristics of its reaction, if well thought out, may open up new paths of chemical synthesis and open unprecedented methods. We researchers, when we work hard at this place, hope to promote the entry of this material in the future with minimal efforts, develop infinite possibilities, and become the cause of benefiting the world and the people.
Where to Buy Benzenesulfonic Acid, 4-Fluoro- in China?
As a trusted Benzenesulfonic Acid, 4-Fluoro- manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading Benzenesulfonic Acid, 4-Fluoro- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 4-fluorobenzenesulfonic acid?
"Tiangong Kaiwu" has a saying: "There are two kinds of sugarcane, which are produced in a wide range of areas, and the other side merges to obtain only eleven of them. The one that resembles bamboo and is large is fruit cane, which is cut off raw and eaten, and the juice is palatable, so it cannot be made into sugar. The one that resembles dice and the small one is sugar cane, which can hurt the lips and tongue when eaten, and people dare not eat it. Both white frost and red sand are produced from here." 4 - The main use of cane sugar in sugarcane is to make sugar.
Sugarcane is divided into sugar cane and fruit cane. Fruit cane is juicy and sweet, and is suitable for living food. Although sugar cane has a poor taste, it is an excellent raw material for making sugar. Since ancient times, people have discovered the sugar potential of sugar cane,
After juicing the sugar cane, impurities are removed, and then boiled, the water is gradually lost, and the concentration of the sugar liquid is increased. When it reaches a certain level, it can be cooled and crystallized to obtain sugar. It can be made into a variety of sugars to meet different needs.
Sucrose is widely used in diet. It can increase sweetness, flavor, and texture. It is used to make various desserts and pastries. It is also used for cooking and seasoning to add unique flavors. It supplies energy for the human body and is indispensable in the food industry. It can be used as a preservative, prolongs the shelf life of food, and can also be used as a moisturizer to maintain food moisture.
In addition, sucrose also has a place in the field of medicine. It can be used as a pharmaceutical excipient to improve the taste and facilitate patients In the production of some traditional medicines, cane sugar can help shape drugs and stabilize ingredients. At the same time, it is also one of the raw materials of cosmetics, which can moisturize the skin and make it softer and more delicate. In short, cane sugar contained in 4-sugarcane plays a key role in diet, medicine, daily chemicals and many other aspects.
What are the physical properties of 4-fluorobenzenesulfonic acid?
"Tiangong Kaiwu" is a scientific and technological masterpiece written by Song Yingxing in the Ming Dynasty, which describes the principle of all things in classical Chinese. As far as 4-hydroxyproline is concerned, this is obtained after proline is hydroxylated, and has unique physical properties.
4-hydroxyproline is white crystalline and has a pure appearance. It has a certain solubility, can be moderately dissolved in water, and the dissolution process is relatively mild without violent reaction. The melting point is about 274 ° C. At this temperature, the substance changes from solid to liquid, showing stable thermal transition characteristics, reflecting the change of its molecular structure under specific energy input.
4-hydroxyproline has a moderate density, giving it a specific form and behavior in different environments. Its crystal structure is regular and orderly, and the intermolecular force is stable. This structural feature has a profound impact on its physical properties, such as determining its density, melting point and other key properties.
4-hydroxyproline is odorless and has a slightly bitter taste, which makes it not introduce additional bad odors in different application scenarios, and does not interfere with the original flavor of the product when applied in food, medicine and other fields.
These physical properties determine that 4-hydroxyproline has important functions in living organisms. In collagen, 4-hydroxyproline participates in maintaining its structural stability and contributes greatly to the strength and toughness of biological tissues. In the industrial field, its unique physical properties also provide the basis for related Product Research & Development and production, such as in the synthesis of some special materials, its properties can be used to regulate material properties.
What are the chemical properties of 4-fluorobenzenesulfonic acid?
Borax is an important compound of boron, which has unique chemical properties and is widely used in many fields. The following is described in detail by you.
Borax is white crystalline and its chemical formula is $Na_2 [B_4O_5 (OH) _4] · 8H_2O $. Borax is water-soluble and has a high solubility in hot water. When dissolved, borax undergoes a hydrolysis reaction, resulting in an alkaline solution.
When borax encounters acid, it reacts to form boric acid. This reaction is as follows: $Na_2B_4O_7 + 2HCl + 5H_2O = 4H_3BO_3 + 2NaCl $. Boric acid is less acidic, but this reaction shows that borax can interact with acid.
When borax is heated, it gradually loses its crystal water. When heated to a certain extent, the crystal water is completely removed, and borax will undergo a series of complex chemical changes, eventually forming boron oxides and other products.
Borax can react with metal ions to form complexes with specific colors or properties. For example, with some transition metal ions, it can form structurally stable complexes. This property is often used in analytical chemistry to identify and separate certain metal ions.
Borax can enhance the thermal stability and transparency of glass in the glass industry; in the enamel industry, it can improve the luster and firmness of enamel; in the pharmaceutical field, it can be used as a disinfectant. These uses are closely related to the chemical properties of borax, such as its ability to react with other substances and the alkalinity of aqueous solutions.
The chemical properties of borax are rich and diverse, which make it indispensable in many fields such as industry, medicine, and scientific research.
What is the production method of 4-fluorobenzenesulfonic acid?
The method of generating acid in the river is very good, and it involves the realm of subtle technology. Ancient alchemists and poets have much to explore here, but their methods are either secret or scattered in ancient books.
In the past, there was a method of gathering the essence of mountains and rivers. Swimming up the river, the river comes out of the pool, and it is suitable for the clear. When the river swims, it is like fairy herbs such as Shiba and Poria cocos, which are developed at the end of the study and introduced, and sprinkled in the river. The river eats it, and it produces wonderful things. When it is completed, capture its liver and steam it with a secret method, you can get the beginning of the river's acid. For the first time, it is necessary to immerse the jade dew in the water, and place it in the place where it is connected. For ninety-nine and eighty-one days, there will be a river of refined acid.
Another way is to borrow the earth and the earth. On the night of the moon, at the foot of the mountain, dig the cellar. Live by the river, in the cellar, the bottom of which is a stone with five elements living together, and the stone is covered with gold. At night, the moon is full, and the moon is full of sympathies between the mountains and the moon, and the gold is transparent, and the river enters the river. On such a ten-day day day, the river is full of and. Take it, use the kettle of purple wine, boil it slowly over a slow fire, and wait for the juice to be boiled, and then use the spoon of peach wood, mix it evenly, and condense it. You can also get the acid of the river.
What's more, in ancient times, seek the method of immortals. There is an immortal cave in the mountains, and there is a real acid in the river. Those who enter the cave need to be determined and tested like a horse. If you get the guidance of the immortals, use the Xianzhi fairy grass to make the river together, and use the water of the fairy spring to burn the fire. Over the years, the river is made of acid. Its effect is extraordinary, and it is comparable to the usual method.
However, all the methods can be done, or it may take the sky to benefit the local people, or it may be involved in the environment. In today's world, if you want to seek the acidity of the river, you can also read ancient books, seek the wisdom of the previous, and then combine the skills of the next, or you can obtain its exquisite method.
What are the precautions for 4-fluorobenzenesulfonic acid in storage and transportation?
4 - Gracillic acid in storage and transportation, need to pay attention to many matters. This is the key to the quality and function of Gracillic acid.
When storing, the first environmental temperature. Gracilaria algae acid likes low temperature and dry environment, it should be stored in a cool place to prevent its deterioration due to high temperature. If placed in a high temperature environment, Gracillic acid may accelerate decomposition, resulting in the loss of its active ingredients and greatly reduced quality.
Humidity should not be underestimated. Humid environment can easily make Gracillic acid damp and agglomerate, affecting its dispersion and use effect. Therefore, the storage place must be kept dry, and desiccants can be used to maintain the dry environment.
In addition, light also has an effect on Gracillic acid. Long-term light exposure, or cause photochemical reactions to occur, changes its chemical structure and reduces its performance. Storage should be protected from strong light, and it is best to store in opaque containers.
As for transportation, stability is extremely important. Gracillic acid is mostly powdery or granular. If it is too bumpy during transportation, it may cause damage to the packaging and product leakage. Therefore, the packaging needs to be firm, and the transportation vehicle should run smoothly to avoid violent vibrations and collisions.
In addition, the temperature and humidity of the transportation environment should also be controlled. Temperature and humidity conditions similar to those of storage should be maintained to prevent damage to the quality of Gracillic acid due to drastic changes in temperature and humidity during transportation.
At the same time, it should be isolated from other chemicals during transportation. Gracillic acid may react with certain chemicals to cause it to deteriorate, so it needs to be transported separately to ensure its chemical stability. In this way, the purpose of storing and transporting Gracillic acid can be achieved to ensure its quality and performance.