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Benzenemethanol, 4-Chloro-3-Fluoro-

Benzenemethanol, 4-Chloro-3-Fluoro-

Hongda Chemical

Specifications

HS Code

453250

Chemical Formula C7H6ClFO
Molar Mass 160.57 g/mol
Appearance Solid (usually)
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone

As an accredited Benzenemethanol, 4-Chloro-3-Fluoro- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 4 - chloro - 3 - fluorobenzenemethanol in a sealed, labeled chemical - grade bottle.
Storage **Storage of 4 - chloro - 3 - fluoro - benzenemethanol**: Store this chemical in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly sealed container to prevent moisture and air exposure, which could potentially lead to degradation. Isolate it from oxidizing agents and incompatible substances to avoid chemical reactions. Label the storage clearly for easy identification and safety.
Shipping 4 - chloro - 3 - fluoro - benzenemethanol is a chemical. Shipping should be in accordance with regulations for hazardous or chemical goods. Ensure proper packaging to prevent leakage, and label clearly with details for safe transportation.
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Benzenemethanol, 4-Chloro-3-Fluoro- Benzenemethanol, 4-Chloro-3-Fluoro-
General Information
Historical Development
"Memorizing the History of 4-Chloro-3-Fluorobenzyl Alcohol"
Fu 4-chloro-3-fluorobenzyl alcohol is also a product of chemistry. Trace back to its source, at the beginning, everyone explored the field of chemistry, but did not hear of this thing. Later, after the study of various sages, gradually observed.
In the past, the craftsmen exhausted their minds, in the experimental room, with various materials, through complex reactions, to obtain this compound. When it was first obtained, only its appearance was known, and its properties and uses were not yet known.
In the following years, scholars were reluctant to study its properties and find out how it can react with things. After years of tempering, they found that it has great potential in the fields of medicine and materials. As a result, it has gradually been reused in industrial production and has become an indispensable existence in the field of chemistry. Its process is also a lesson for future generations to study chemistry.
Product Overview
"Introduction to 4-chloro-3-fluorobenzyl alcohol"
Fu4-chloro-3-fluorobenzyl alcohol is a key compound in the field of organic synthesis. It has a unique molecular structure, chlorine and fluorine atoms are cleverly connected to the benzene ring, and the benzene ring is connected with a methanol group. This special structure gives it a variety of chemical activities.
In organic synthesis reactions, it can often be used as an important intermediate. Due to the existence of methanol groups, it can participate in many nucleophilic substitution reactions, and can react with a variety of halogenated hydrocarbons, acyl halides and other reagents to construct complex organic molecular structures. The introduction of chlorine and fluorine atoms not only affects the electron cloud distribution of molecules, but also has a significant effect on reaction selectivity. It has great potential in the preparation of fine chemicals such as medicines and pesticides, and may be the cornerstone for the creation of new high-efficiency active ingredients.
Physical & Chemical Properties
Today there is a substance called 4-chloro-3-fluorobenzyl alcohol (Benzenemethanol, 4-Chloro-3-Fluoro-). Its physical and chemical properties are related to many things. The appearance of this substance may be in a specific form, or it may be crystalline, or it may be a powder, and the color is also different. Its melting and boiling point is an important physical characteristic, and the boiling point determines its phase transition at a specific temperature.
In terms of solubility, it varies in various solvents, and the degree of solubility varies in water and organic solvents. This property is related to its dispersion in the reaction system and its ability to participate in the reaction. Chemically, chlorine, fluorine atoms and benzyl alcohol groups in its molecular structure give unique activities, and can participate in a variety of chemical reactions, or nucleophilic substitution, or redox, depending on the reaction conditions. The study of the physical and chemical properties of this substance is of great significance in many fields such as chemical industry and medicine.
Technical Specifications & Labeling
Today there is a product called "Benzenemethanol, 4 - Chloro - 3 - Fluoro-". In the field of chemical industry, its technical specifications and identification (commodity parameters) are the key. Looking at this substance, the technical specifications depend on its purity geometry, the proportion of ingredients, and the preparation method must follow the precise order, from the selection of raw materials to the control of reaction conditions. And the marker shows its characteristics, such as physical properties, color and taste morphology, chemical activity geometry, and whether there is any harm. These two, such as two wheels of a car and two wings of a bird, are indispensable. In the production and application, the technical specifications ensure the same quality, and the logo allows the user to know the details, use it safely, and obtain the wonders of this substance, which goes smoothly in the chemical industry.
Preparation Method
"Method for making ethyl benzoate"
To prepare 4-chloro-3-fluorobenzyl alcohol (Benzenemethanol, 4-Chloro-3-Fluoro-), prepare the raw materials first. Take an appropriate amount of p-chlorofluorobenzaldehyde, this is the starting quality.
The preparation process is as follows: In the clean reactor, put p-chlorofluorobenzaldehyde, use sodium borohydride as the reducing agent, add it slowly, and control the reaction temperature in the low temperature range, about 0 ° C to 5 ° C. This is the first step of the reaction. Sodium borohydride is fully reacted with p-chlorofluorobenzaldehyde, and the aldehyde group gradually converts to a hydroxyl group to form a crude product of 4-chloro-3-fluorobenzyl alcohol.
Then, the crude product is purified by distillation, and the fraction in a specific temperature range is collected at about 120 ° C to 130 ° C. The impurities are removed to obtain pure 4-chloro-3-fluorobenzyl alcohol. This process requires strict control of temperature, raw material ratio and reaction time to obtain high-quality products.
Chemical Reactions & Modifications
Yu Taste is dedicated to the research of chemical products, and recently focused on Benzenemethanol, 4 - Chloro - 3 - Fluoro - this compound. Looking at its chemical reactions, there are often things to explore. Chemical changes, such as the symmetry of yin and yang, each thing meets, and the change is gratuitous.
The reaction of this compound has a specific appearance. Its properties are variable, or it varies depending on temperature and reagents. In the past, it was said: "Things have a beginning and an end, and things have a end." Chemical changes also have their beginning. If you want to study the wonders of their changes, you must carefully investigate the conditions of the reaction, temperature, pressure, and the proportion of reagents, which are all key.
When using this Benzenemethanol, 4 - Chloro - 3 - Fluoro - to participate in the reaction, observe its changes, or generate new products, or modify their properties. The principle of this change is like the inference of yin and yang, and the changes are endless. I will explore its chemical reaction and modification with a rigorous heart, hoping to gain something and add to the chemical industry.
Synonyms & Product Names
4-Chloro-3-fluorobenzyl alcohol (Benzenemethanol, 4-Chloro-3-Fluoro-) is a synonymous name and a commodity name, which is quite important. In the course of my chemical inquiry, it is very beneficial to know the various names of the same substance.
Today, 4-chloro-3-fluorobenzyl alcohol may have aliases to suit different situations. Among the businesses, the names of its products also vary depending on the merchants and uses. This is all due to the long development of the chemical field, and the names used in different places and times are different.
When we investigate, we can carefully identify the synonymous name of 4-chloro-3-fluorobenzyl alcohol and the name of the product, so that everything can go smoothly in the experiment and study, without confusion due to the title, so that we can enjoy the world of chemical research.
Safety & Operational Standards
Title: Safety and Operating Specifications for 4-Chloro-3-Fluorobenzyl Alcohol Products
The chemical industry is related to people's livelihood and safety. Today's discussion of Benzenemethanol, 4-Chloro-3-Fluoro - This product, its safety and operating specifications, cannot be ignored.
This product is often involved in fine processes in chemical preparation. When handling, the first protection. All kinds of protective equipment, such as special protective clothing, tight goggles, and high-efficiency protective masks, are indispensable. Wear protective clothing to protect against its damage to the skin; wear goggles to prevent splashing liquid from hurting the eyes; wear a mask to avoid the inhalation of harmful gases.
Furthermore, the operating environment should be careful. The place of operation should be well ventilated so that harmful gases can dissipate quickly and avoid accumulation. Lighting should also be sufficient and explosion-proof to prevent accidental sparks from causing dangerous situations. The equipment used must be clean and fit, and checked regularly to ensure its performance.
As for storage, there are also regulations. When placed in a cool, dry and ventilated place, away from fire and heat sources. It must be stored separately with oxidants, acids, etc., to avoid chemical reactions and cause disasters. When handling, the action should be slow, light loading and light unloading to prevent damage to the container and material leakage.
If there is unfortunately a material leakage, do not panic. Quickly start ventilation equipment and evacuate the surrounding people. Emergency responders need complete protective equipment, use suitable materials to absorb and contain leaks, and properly handle them, so as not to pollute and the environment.
The safety of the husband is as important as Mount Tai. In the production, operation and storage of 4-Chloro-3-Fluoro-Benzenemethanol, strictly abide by the norms, so as to ensure that nothing goes wrong and promote the stable progress of the chemical industry.
Application Area
In the field of chemistry, 4-chloro-3-fluorobenzyl alcohol (Benzenemethanol, 4-Chloro-3-Fluoro-) has a wide range of applications. In the development of medicine, it is an important role. With its characteristics, it can be used in the process of drug synthesis, and it can help with medicine and cure diseases.
And in the field of material preparation, it also has its uses. It can contribute to the synthesis of special materials, making the materials have different properties, or very tough, or have specific reactions, suitable for various special situations.
Furthermore, in the realm of fine chemicals, 4-chloro-3-fluorobenzyl alcohol can be used as a key raw material, laying the foundation for the output of many fine chemicals, improving product quality, and meeting diverse needs. In various application fields, it shines like a pearl, playing an extraordinary role and promoting the progress of various undertakings.
Research & Development
A chemical was developed today, named 4-chloro-3-fluorobenzyl alcohol (Benzenemethanol, 4-Chloro-3-Fluoro-). This substance has a wide range of uses and has potential in the fields of medicine and materials.
We have explored the synthesis method of it, and after many attempts, we have obtained a feasible path. At first, a specific halogenated aromatic hydrocarbon was used, and a fluoro group was introduced through nucleophilic substitution; after a series of reactions, chlorine atoms were successfully added, and the final product was obtained.
However, the synthesis process was not smooth sailing and encountered many problems. If the reaction conditions are harsh, the yield will be affected if the temperature and pressure are slightly deviated; and there are many side reactions, the separation and purification of the product is difficult. We have repeatedly optimized the conditions and improved the method, and finally made progress.
Looking to the future, we hope to deepen research, improve yield and purity, expand its application range, and promote the development of this compound in various fields, contributing to scientific progress and social development.
Toxicity Research
It is very important to study the toxicity of halogenated benzyl alcohols, especially 4-chloro-3-fluorobenzyl alcohol (Benzenemethanol, 4-Chloro-3-Fluoro-). Such substances may involve many risks, which are related to life, health and ecological environment.
In the past, more attention was paid to its chemical synthesis and properties, but there was still a lack of toxicity research. However, toxicity research is the key to a comprehensive understanding of this compound. We should use a scientific method to explore its impact on organisms and observe its toxicity changes under different environmental conditions.
Experiments have shown that 4-chloro-3-fluorobenzyl alcohol may damage biological cells and interfere with normal physiological functions. Although the current conclusion is not conclusive, there is a latent risk. It is necessary to study its mechanism of action and accurately measure its toxicity to provide a basis for preventing harm and rational application to ensure human and environmental well-being.
Future Prospects
The future of the future is of paramount importance to our chemical research. Today there is a product called "Benzenemethanol, 4 - Chloro - 3 - Fluoro -". This compound is powerful, and its application in the field may become the cornerstone of new products to solve the suffering of many patients. In the field of materials, it is also expected to assist in the research of high-performance materials and promote the next step in science and technology. The road ahead may be exciting, but we will keep the heart of exploration and move forward. Unexpected, we will definitely be able to reveal more secrets, make it beneficial to the world, and develop the power of people. This is our unremitting pursuit.
Where to Buy Benzenemethanol, 4-Chloro-3-Fluoro- in China?
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Frequently Asked Questions

As a leading Benzenemethanol, 4-Chloro-3-Fluoro- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of 4-chloro-3-fluorobenzyl alcohol?
4-Deuterium-3-tritium ethyl methyl ether has unique chemical properties. Deuterium and tritium are both isotopes of hydrogen. In this compound, the presence of deuterium and tritium makes its physical and chemical properties different from ordinary ethyl methyl ether.
In terms of its reactivity, because the mass of deuterium and tritium atoms is greater than that of hydrogen atoms, the vibration frequency of carbon-deuterium and carbon-tritium bonds is reduced, and the bond energy is relatively high. This involves the reaction of carbon-deuterium and carbon-tritium bonds breaking, and the rate is slower than that of those containing ordinary carbon-hydrogen bonds. For example, in some pyrolysis and oxidation reactions, the reaction process of 4-deuterium-3-tritium ethyl methyl ether may be different from that of ordinary ethyl methyl ether.
In terms of polarity, although deuterium and tritium substituted hydrogen have little effect on the overall molecular polarity, due to their mass differences, they may behave differently in some processes that rely on intermolecular forces, such as crystallization and dissolution. In specific solvents, its solubility may be slightly different from that of ordinary ethylmethyl ether.
And because it contains radioactive tritium, 4-deuterium-3-ethyltritium methyl ether is radioactive. This radioactivity requires special protection and treatment measures when using and storing the compound. Its radioactivity or affects surrounding molecules, triggering chemical reactions related to radioactive decay, adding a unique aspect to its chemical properties.
In addition, due to the mass difference between deuterium and tritium, the position of the relevant vibration absorption peak in the infrared spectrum is different from that of ordinary ethyl methyl ether. This can be used as an important basis for the identification and analysis of the compound. By means of spectral characteristics, the structure and properties of 4-deuterium-3-tritium ethyl methyl ether can be accurately identified and studied.
What are the physical properties of 4-chloro-3-fluorobenzyl alcohol?
4-Cyanogen-3-fluorobenzylacetate is one of the organic compounds. Its physical properties are particularly important and are related to many practical applications.
First of all, its appearance is often colorless to light yellow liquid, with a clear and transparent texture, which is easy to observe and operate in many chemical reactions and industrial processes.
times and boiling point, about a specific temperature range. The characteristics of boiling point are crucial in separation, purification and other processes. In operations such as distillation, according to its boiling point, it can be accurately separated from the mixture to ensure the purity of the product.
Melting point is also an important physical property. Although the specific value may vary slightly due to environmental factors and other factors, the approximate range is relatively stable. Knowing the melting point helps to control the physical state transformation of substances at different temperatures, which is of great significance in storage and transportation. If the storage temperature is improper, or its state is changed, it will affect the quality.
Furthermore, the density of this compound has a specific density value. Density information is indispensable in material measurement and mixing ratio determination. In chemical production, accurate calculation of density can ensure that the proportion of each raw material is appropriate and the reaction can proceed smoothly.
The solubility cannot be ignored. It exhibits good solubility in organic solvents such as ethanol and acetone, but poor solubility in water. This characteristic determines its application scenarios in different solvent systems. In the organic synthesis reaction, a suitable organic solvent can be selected to dissolve it to promote the full occurrence of the reaction.
In addition, its refractive index also has a specific value. The refractive index can be used as a reference index to identify the purity and concentration of the compound. In the quality inspection process, by measuring the refractive index, it can quickly determine whether the product meets the standard.
The physical properties of 4-cyanogen-3-fluorobenzylacetate, such as appearance, boiling point, melting point, density, solubility, refractive index, etc., are related to each other and together build its material characteristics. It is of key value in many fields such as chemical industry and medicine, and provides an important basis for its synthesis, application, storage and transportation.
What are the main uses of 4-chloro-3-fluorobenzyl alcohol?
4-Bromo-3-chloroacetophenone is a crucial raw material in the field of organic synthesis and is widely used in many industries such as medicine, pesticides, and dyes.
In the field of medicine, it is mainly used to synthesize a variety of drugs with specific biological activities. For example, in the synthesis of some anti-tumor drugs, 4-bromo-3-chloroacetophenone can act as a key intermediate. Due to the presence of bromine and chlorine atoms in its molecular structure, it can participate in specific chemical reactions, thereby constructing active structures that combine with tumor cell targets, helping to develop more therapeutic anti-cancer drugs. In addition, in the development of antibacterial drugs, with the help of its unique structure, pharmaceutical ingredients that have inhibitory or killing effects on specific pathogens can be synthesized through a series of reactions.
In the pesticide industry, 4-bromo-3-chloroacetophenone can be used as an important starting material for the synthesis of new pesticides. With its chemical properties, insecticides with efficient pest control effects or fungicides with good preventive and therapeutic effects on plant diseases can be prepared. For example, by reacting with other organic compounds, pesticides with special action mechanisms can be generated, which can precisely act on the specific physiological processes of pests or pathogens, improve the control effect of pesticides, and reduce the impact on the environment.
In the field of dyes, 4-bromo-3-chloroacetophenone can be used to synthesize dyes with unique colors and properties. Due to its structure, it can participate in the construction of dye molecules, giving dyes better stability, light resistance and other excellent properties. For example, synthesizing reactive dyes for textile dyeing makes dyed fabrics bright and long-lasting, and not easy to fade.
In summary, 4-bromo-3-chloroacetophenone plays an indispensable role in many important industrial fields due to its unique chemical structure and reactivity, and is of great significance to promoting the development of related industries.
What is the synthesis method of 4-chloro-3-fluorobenzyl alcohol?
To prepare 4-cyanogen-3-fluorobenzyl acetate, the following ancient method can be used.
First take an appropriate amount of 3-fluorobenzyl halide and place it in a clean reactor. This halide is selected as the appropriate halogen atom activity to facilitate subsequent reactions. Add an appropriate amount of cyanide reagent to the kettle, usually such as potassium cyanide or sodium cyanide, which are used as cyanide donors in the reaction. It should be noted that cyanide is highly toxic, and the operation must be cautious, in a well-ventilated place and strictly follow the procedures. To promote the reaction, add an appropriate amount of phase transfer catalyst, such as quaternary ammonium salts, which can improve the transfer of substances between the two phases and make the reaction smoother. Control the reaction temperature to a suitable range, usually slightly higher than room temperature, about 30-50 degrees Celsius, and continue to stir. After several times, 3-fluorobenzyl halide reacts fully with the cyanide reagent to obtain 3-fluorobenzyl cyanide. The key to this step of reaction lies in the precise control of temperature, reagent ratio and reaction time, otherwise side reactions will easily occur and the product will be impure.
Then, transfer the prepared 3-fluorobenzyl cyanide to another reaction vessel, add an appropriate amount of acetic anhydride or acetyl halide, which are the sources of acetyl groups. And add a suitable catalyst, such as Lewis acid, to catalyze the acetylation reaction. Heat up to 60-80 degrees Celsius, maintain stirring, and after a few hours, 3-fluorobenzyl cyanide fully interacts with the acetylation reagent to form 4-cyanogen-3-fluorobenzyl acetate.
After the reaction is completed, the product is often mixed with unreacted raw materials, by-products and catalysts and other impurities. Therefore, a separation and purification process is required. First, the product is extracted with an organic solvent to enrich the product in the organic phase, and then distilled to separate the pure 4-cyanogen-3-fluorobenzyl acetate according to the different boiling points of each component. The entire process, from the selection of raw materials, the control of reactions, to the purification method, requires fine operation to obtain high-purity target products.
What are the precautions for the storage and transportation of 4-chloro-3-fluorobenzyl alcohol?
4-Cyanogen-3-fluorobenzylacetate should be stored and transported with caution, which involves many precautions.
The first storage environment, this compound should be placed in a cool, dry and well-ventilated place. Because it is quite sensitive to temperature and humidity, high temperature is easy to decompose, and humidity may cause deterioration, so the temperature should be controlled in a specific range, and the humidity should not exceed a certain value. And it needs to be stored separately with oxidants, acids, bases and other substances to prevent dangerous chemical reactions.
Furthermore, the choice of storage container is also critical. It is advisable to use corrosion-resistant and well-sealed containers, such as special glass or plastic bottles, and the containers must be clearly labeled, indicating the name, nature and hazards of the compound.
As for transportation, it is necessary to ensure that the packaging is stable. Packaging materials should be shock-resistant and collision-resistant to withstand bumps in transit. The means of transportation should also be clean, dry, and should not transport goods that come into contact with 4-cyanogen-3-fluorobenzylacetate. Transport personnel should be familiar with the properties of this compound and emergency treatment methods. In case of emergencies, they can dispose of it quickly and properly.
In addition, relevant regulations and standards must be strictly followed regardless of storage or transportation. From the specification of storage conditions to the requirements of transportation qualifications, there must be no slack. In this way, the safety of 4-cyanogen-3-fluorobenzyl acetate during storage and transportation can be ensured, accidents can be avoided, and the safety of personnel and the environment can be guaranteed.