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What is the chemical structure of the product called "Benzenemethanamine, α, 2-Dimethyl-3- (Trifluoromethyl) -, (α r) -"?
The substance referred to in this "Benzenemethanamine, α, 2-Dimethyl-3- (Trifluoromethyl) -, (α r) -" is analyzed according to the chemical naming rules as follows:
Its core structure is phenethylamine, that is, "Benzenemethanamine", which is the basic structure formed by the connection of phenyl and amino groups.
"α, 2-Dimethyl-3- (Trifluoromethyl) -" indicates the substituent status. "α-Dimethyl" indicates that there are two methyl groups attached to the carbon atom at the α position directly connected to the benzene ring; "2-Dimethyl" means that there is also a methyl group at the 2nd position of the benzene ring; "3 - (Trifluoromethyl) " indicates that there is a trifluoromethyl group at the 3rd position of the benzene ring.
" (α r) -" indicates that the configuration of the carbon atom at the α position is the r configuration, which is a description of the specific chiral central space configuration.
In summary, the chemical structure of this substance is phenethylamine as the parent nucleus, with two methyl groups at the α position, methyl groups at the 2 position of the benzene ring, trifluoromethyl groups at the 3 position, and the carbon atom at the α position has the r configuration. The structure can be imagined as an ethylamine structure connected with a specific substituent and a specific configuration on one side of the benzene ring, and each substituent is orderly distributed on the corresponding check point according to a specific position.
"Benzenemethanamine, α, 2-Dimethyl-3- (Trifluoromethyl) -, (α r) -" Where are the products used?
"Benzenemethanamine, α, 2 - Dimethyl - 3- (Trifluoromethyl) -, (α r) -" is α-methyl-2-methyl-3- (trifluoromethyl) aniline, which is used in many fields.
In the field of medicine, it can be used as an intermediate in drug synthesis. Due to its unique chemical structure, it can participate in a variety of reactions and build complex drug molecules. For example, when developing drugs for the treatment of specific neurological diseases, its structural properties can be used to modify and optimize drug activity and selectivity, enhance affinity for specific targets, thereby improving efficacy and reducing side effects.
In the field of materials science, it can be used to prepare special functional materials. Due to its trifluoromethyl content, it can endow materials with unique properties, such as improving the corrosion resistance, thermal stability and surface activity of materials. Special coating materials can be synthesized to protect metal surfaces and improve their corrosion resistance in harsh environments; or functional polymer materials can be prepared for use in electronic devices to improve the electrical properties of materials.
In the field of organic synthesis, as an important intermediate, it can be combined with different reagents through a variety of chemical reactions to construct diverse organic compound structures. For example, by alkylating with halogenated hydrocarbons to expand the molecular carbon chain; or reacting with carbonyl compounds to construct complex structures such as nitrogen-containing heterocycles, providing more structural diversity for organic synthesis chemistry and assisting in the development and synthesis of new compounds.
"Benzenemethanamine, α, 2-Dimethyl-3- (Trifluoromethyl) -, (α r) -" What are the physical properties of the product?
"Benzenemethanamine, α, 2 - Dimethyl - 3- (Trifluoromethyl) -, (α r) -" The corresponding substance is α, 2 - dimethyl - 3- (trifluoromethyl) aniline (with a specific α configuration). The physical properties of this substance, let me tell you one by one.
Its appearance may be a colorless to light yellow liquid, which exists in a liquid state at room temperature and pressure. Looking at its color, it is roughly in this category due to differences in purity and preparation process, or slightly different.
When it comes to odor, it may have a special amine smell, pungent and volatile to a certain extent. Its volatility results in an open environment, and the smell is easy to diffuse, which can be detected by humans.
Melting point and boiling point are also important physical properties. The boiling point is determined by factors such as intermolecular forces and molecular weights. From the perspective of material structure, fluorine atoms and amines, intermolecular forces have their own characteristics, resulting in boiling points in a specific range. However, the exact value still needs to be accurately determined by experiments, but according to similar structural compounds, the boiling point may be within a certain range. In terms of melting point, due to molecular configuration and interaction, or in a lower temperature range, the specific value also needs to be determined by experiments.
In terms of solubility, due to the presence of polar amine groups, non-polar benzene rings and fluorine-containing groups, in organic solvents such as ethanol, ether, etc., it may have certain solubility. Polar amine groups can form hydrogen bonds or other intermolecular forces with organic solvents to help them dissolve; the non-polar part interacts with the non-polar region of the organic solvent, which is also conducive to the dissolution process. However, in water, its hydrophobic fluoroalkyl and benzene rings have limited solubility.
Density is one of the important physical properties of a substance. The density of this substance is different from that of water, or due to molecular composition and structure. Due to the large atomic weight of fluorine atoms, it has an impact on the overall density, so the density may be comparable to that of common organic compounds, but the exact value needs to be measured experimentally.
This is a summary of the physical properties of "α, 2-dimethyl-3- (trifluoromethyl) aniline", but accurate data still depend on rigorous experimental determination.
"Benzenemethanamine, α, 2-Dimethyl-3- (Trifluoromethyl) -, (α r) -" What is the preparation method of the product?
The method of preparing " (α r) -α, 2-dimethyl-3- (trifluoromethyl) aniline" is an important matter in chemical synthesis. The method has various paths, and the common ones are started by the corresponding benzaldehyde derivatives.
First take a suitable 2-methyl-3- (trifluoromethyl) benzaldehyde, use a reducing agent, such as sodium borohydride or lithium aluminum hydride, and perform a reduction reaction in a suitable solvent, such as methanol or tetrahydrofuran, to obtain 2-methyl-3- (trifluoromethyl) benzyl alcohol. This step requires moderate temperature control and attention to the reaction process to preserve the yield.
Next, the resulting alcohol is converted into a halide, which can be interacted with a halogenating agent, such as phosphorus tribromide or thionyl chloride, to obtain 2-methyl-3- (trifluoromethyl) benzyl halogen under appropriate conditions.
Then, the halide is reacted with ammonia or aminating reagents in a solvent, such as ethanol or toluene, and nucleophilic substitution is performed to obtain the target product (α r) -α, 2-dimethyl-3- (trifluoromethyl) aniline. In this process, it is also crucial to choose a suitable base to promote the reaction.
Or there are other methods, from different starting materials, according to the principle of organic synthesis, through multi-step transformation, can also achieve this goal. The way of synthesis requires detailed study of the reaction mechanism and precise control of conditions in order to achieve the purpose of high purity and high yield.
What is the market outlook for the product "Benzenemethanamine, α, 2-Dimethyl-3- (Trifluoromethyl) -, (α r) -"?
"Benzenemethanamine, α, 2 - Dimethyl - 3 - (Trifluoromethyl) -, (α r) -" is α, 2 - dimethyl - 3 - (trifluoromethyl) aniline ((α r) - configuration), which is a fine chemical with a specific structure in organic synthesis.
Looking at its market prospects, it is in a booming trend. From the field of medicine, with the advancement of innovative drug research and development, amine compounds containing special substituents are increasingly in demand as key intermediates. The unique trifluoromethyl and chiral structure of this compound can endow drugs with better fat solubility, metabolic stability and biological activity. In the development process of many new anti-cancer and antiviral drugs, such intermediates with specific spatial structures and electronic effects are often required, so their market potential is huge in the pharmaceutical synthesis industry chain.
In the field of materials science, with the deepening of functional materials research, fluorinated organic amines can be used to prepare high-performance polymers, liquid crystal materials, etc. Because of their fluorine-containing structure, they can improve the chemical corrosion resistance, thermal stability and optical properties of materials. For example, when preparing high-end display liquid crystal materials, the introduction of such structures can optimize the arrangement of liquid crystal molecules and improve the display effect, thus opening up new application fields and market spaces for the product.
Furthermore, with the popularization of the concept of green chemistry, the requirements for green and efficient synthesis processes are gradually increasing. If innovative and environmentally friendly synthesis routes emerge, which can effectively reduce production costs and reduce pollution emissions, it will further expand its market application scope, attract more downstream industries to adopt, and make the market prospect broader.