α-Amino-2- (trifluoromethyl) phenylacetic acid, which has a wide range of uses. In the field of medicine, it is often an important pharmaceutical intermediate. The synthesis of many drugs relies on it as the basic raw material. Due to its specific chemical structure, it is endowed with unique reactivity and can participate in a variety of chemical reactions. After ingenious transformation, complex molecular structures with specific pharmacological activities are constructed.
In organic synthesis chemistry, it also plays a key role. Chemists can prepare a series of organic compounds with novel structures by modifying and modifying their structures. Through various reactions, such as esterification, amidation, etc., products with different functions are derived, expanding the variety and application range of organic compounds.
In the field of pesticide research and development, α-amino-2- (trifluoromethyl) phenylacetic acid can also be used. Or it can be used as a key raw material for the synthesis of new pesticides. With its special structure, pesticides are endowed with excellent characteristics such as high efficiency, low toxicity, and environmental protection, providing new and effective means for agricultural pest control.
And because it contains special functional groups such as trifluoromethyl, amino groups, and carboxyl groups, it may also have potential applications in the field of materials science. For example, in the synthesis of some functional polymer materials, it can be introduced as a functional monomer, giving the material unique properties, such as improving the solubility, thermal stability, and surface properties of the material. Overall, α-amino-2- (trifluoromethyl) phenylacetic acid has important uses and broad application prospects in many fields due to its special structure.

Phenylacetic acid, α-amino-2- (trifluoromethyl), is one of the organic compounds. Its physical properties are quite critical, and it is related to many characteristics of this substance.
First of all, its appearance is often white to white-like crystalline powder. This shape is easy to distinguish, which is the main point for preliminary understanding of its physical characteristics. Just as the ancient books say "white and uniform in quality, if the powder is delicate", this appearance is conducive to preliminary observation and identification.
Furthermore, this substance has a specific melting point. Generally speaking, the melting point is within a certain range, which is an important basis for identifying the purity and characteristics of the substance. Just like in ancient times to identify gold stones, its melting point and other characteristics need to be considered. "The melting point is established, and the authenticity and purity can be judged." By measuring the melting point, it can be determined whether the substance is pure, and it can also be known whether its phase state changes under different conditions.
Solubility is also an important physical property. In some organic solvents, such as ethanol, methanol, etc., there is a certain solubility. Just like "each substance has its own solubility. In alcohols, it is like a fish getting water." This solubility makes it have many applications in organic synthesis, drug preparation and other fields. It can be used as a medium for dissolution and reaction, which is conducive to the progress of various chemical reactions.
In addition, its density also has a specific value, although it is difficult to distinguish with the naked eye, in precise chemical experiments and industrial applications, density data is indispensable, related to the measurement of substances, mixing ratio, etc. "The number of density, accurate to the minute, is related to the cost of balance".
This phenylacetic acid, α-amino-2- (trifluoromethyl), its physical properties such as appearance, melting point, solubility, density, etc., each play an important role in chemical research, industrial production, pharmaceutical manufacturing and many other fields, are the key elements, indispensable.

α-Amino-2- (trifluoromethyl) phenylacetic acid, this is an organic compound with many unique chemical properties.
Looking at its structure, it contains benzene ring, carboxyl group, amino group and trifluoromethyl group. The presence of benzene ring endows it with certain stability and conjugation effect. Because the benzene ring is a closed conjugated system, the electron cloud is uniformly distributed, which improves the stability of the compound and can participate in electrophilic substitution reactions. If under appropriate conditions, it can be halogenated with halogenating agents, and halogen atoms replace hydrogen atoms on the benzene ring; it can also be acylated with acylating reagents.
The carboxyl group is acidic and can partially ionize hydrogen ions in water, exhibiting acidic properties. It can neutralize with bases to form corresponding carboxylic salts and water; it can also esterify with alcohols catalyzed by concentrated sulfuric acid to form esters.
Amino groups are basic, and the lone pair electrons on the nitrogen atom can bind protons. It can react with acids to form salts, such as hydrochloric acid to form hydrochloride salts. At the same time, amino groups are important reaction check points in organic synthesis, and can participate in nucleophilic substitution reactions and react with halogenated hydrocarbons and other electrophilic reagents to form new carbon-nitrogen bonds.
Trifluoromethyl is a strong electron-absorbing group, which has a significant impact on the distribution of compound electron clouds. Due to its strong electron-absorbing effect, the electron cloud density of the benzene ring decreases, and the electrophilic substitution reaction activity on the benzene ring decreases; it also affects the carboxyl group and amino acid and alkalinity, enhances the acidity of the carboxyl group, and weakens the alkalinity of the amino group.
This compound is widely used in the fields of organic synthesis and medicinal chemistry. In drug development, due to its unique chemical properties and structure, it may be used as a key intermediate to construct drug molecules with specific biological activities, laying the foundation for the creation of new drugs.

The synthesis of α-amino-2- (trifluoromethyl) phenylacetic acid is an important task in chemical technology. This synthesis often follows various paths, and the core steps involve specific chemical reactions and delicate manipulations.
The first is often a derivative of phenylacetonitrile as the starting material. Under appropriate reaction conditions, trifluoromethyl is introduced onto phenylacetonitrile, which can be achieved by nucleophilic substitution or other related reactions. After the trifluoromethyl is successfully attached to the phenylacetonitrile structure, a hydrolysis reaction is carried out to convert the cyano group into a carboxyl group to obtain a phenylacetic acid derivative containing trifluoromethyl.
The second is the introduction of amino groups. There are also various strategies for this step. First, reductive amination can be used. The carboxyl group of the phenylacetic acid derivative is first converted into an aldehyde group or a ketone group, and then reacted with ammonia or amine compounds in the presence of a reducing agent to convert the carbonyl group into an amino group, and then obtain the target α-amino-2- (trifluoromethyl) phenylacetic acid.
Or, starting from the benzene ring with suitable substituents, the nucleophilic substitution or addition reaction can be used to gradually construct a side chain containing trifluoromethyl and amino groups, and then converted into this compound by appropriate functional groups. Each step of the reaction requires detailed observation of the reaction conditions, such as temperature, pH, catalyst selection and dosage, etc., which all affect the success or failure of the reaction and the purity of the product. And after each step of the reaction, fine separation and purification operations are often required to remove impurities and obtain pure target products. In this way, after many twists and turns, α-amino-2- (trifluoromethyl) phenylacetic acid can be obtained.

There is no record of the price range of "Benzeneacetic Acid, Alpha - Amino - 2 - (Trifluoromethyl )”（α - amino - 2 - (trifluoromethyl) phenylacetic acid) " in the Compendium of Materia Medica. This substance is a related product of modern chemical synthesis. The Compendium of Materia Medica was written in ancient times, when chemical synthesis technology was far from developed. The book records natural medicinal materials and other content. Its description focuses on the taste, efficacy, origin, etc. of traditional Chinese medicine, rather than the market price of modern synthetic chemicals.
If you want to know the price range of this substance in the market, you should explore it in the modern chemical raw material market and chemical reagent suppliers. Different purity, different packaging specifications, different purchase quantities and market supply and demand conditions will cause their prices to fluctuate. Generally speaking, when the purity is high, the packaging specifications are large and the market demand is strong, the price may be high; conversely, if the purity is low, the packaging specifications are small and the market supply is sufficient, the price may be relatively low. You can obtain more accurate price information through online chemical product trading platforms, consulting relevant chemical reagent dealers, etc.