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Benzeneacetic Acid, 5-Bromo-2-Fluoro-

Benzeneacetic Acid, 5-Bromo-2-Fluoro-

Hongda Chemical

Specifications

HS Code

136197

Chemical Formula C8H6BrFO2
Molar Mass 233.034 g/mol
Appearance Solid (usually white or off - white powder)
Solubility In Water Low solubility
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, dichloromethane
Boiling Point Decomposes before boiling under normal pressure
Melting Point 125 - 127 °C
Pka Approximately 4.2 (similar to benzoic acid derivatives)

As an accredited Benzeneacetic Acid, 5-Bromo-2-Fluoro- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 5 - bromo - 2 - fluoro - benzeneacetic acid, 100g, packaged in a sealed, chemical - resistant container.
Storage 5 - bromo - 2 - fluoro - benzeneacetic acid should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition sources. It should be stored in a tightly - sealed container to prevent moisture absorption and contact with air. Keep it separated from oxidizing agents and incompatible substances to avoid potential chemical reactions. Label the storage container clearly for easy identification.
Shipping 5 - bromo - 2 - fluoro - benzeneacetic acid is shipped in well - sealed containers, compliant with chemical transportation regulations. It's carefully packaged to prevent spills and ensure safe transit, with all relevant safety labels attached.
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Benzeneacetic Acid, 5-Bromo-2-Fluoro- Benzeneacetic Acid, 5-Bromo-2-Fluoro-
General Information
Historical Development
I have heard that phenylacetic acid, a genus of pentabromodifluoride, has been involved in history, but it is not a big deal. In the past, Zhu Xian did not know its nature, and it was difficult to study. At first, only a little understanding of its shape, but not its use.
After several generations, many scholars have devoted themselves to it, and their structure and properties have gradually come to an understanding. Beginning to know that its molecular structure is exquisite and has a unique chemistry.
In the process of synthesis, there are many twists and turns. The former sages tried many techniques, either failed or succeeded, and finally obtained a good method. His method gradually improved, and the yield also increased.
Therefore, this phenylacetic acid, pentabromodifluoride, has been used in various fields of medicine and chemical industry to benefit the world. The progress of its history is actually caused by the efforts of various sages, and it is the basis for future generations to study this substance.
Product Overview
A compound, called Benzeneacetic Acid (Benzeneacetic Acid, 5 - Bromo - 2 - Fluoro-). Its shape is also unique chemical structure. On the benzene ring, bromine and fluorine atoms occupy positions in sequence and are connected to phenylacetic acid. The properties of this compound are related to many fields of organic synthesis.
Looking at its chemical activity, due to the existence of bromine and fluorine, the electron cloud density of the benzene ring changes, resulting in different reactivity. The induction effect of bromine atoms decreases the electron cloud density of the adjacent site and adjusts the electrophilic substitution reactivity. Fluorine atoms have strong electronegativity, which also affects the properties of surrounding chemical bonds. In the process of organic synthesis, 5-bromo-2-fluorophenylacetic acid is often a key intermediate. It can build complex organic molecular structures through a series of reactions with the activity of bromine and carboxyl groups, and may have potential applications in drug development, materials science and many other fields.
Physical & Chemical Properties
The physical and chemical properties of 5-bromo-2-fluorophenylacetic acid are particularly important. Looking at its shape, under room temperature, it is either solid, colored or white crystalline, due to the orderly arrangement of molecular structures. Regarding its melting and boiling point, the melting point has a specific value due to the intermolecular force, or is in a certain temperature range, due to the balance of the attractive force and the repulsion force between molecules; the boiling point also needs to reach a certain energy to break the intermolecular binding.
Its solubility in organic solvents may have different manifestations. In case of alcohol solvents, according to the principle of similar compatibility, if the polarity of the molecules matches, it is soluble, which is related to the matching of the intermolecular force. Its chemical properties, due to the structure of the benzene ring with bromine, fluorine and carboxyl groups, have specific reactivity. The benzene ring can undergo electrophilic substitution, and the bromine and fluorine atoms can affect the reaction check point and rate; the carboxyl group can participate in esterification and other reactions, showing unique chemical behaviors.
Technical Specifications & Labeling
There are chemical substances today, called "Benzeneacetic Acid, 5 - Bromo - 2 - Fluoro -". The matter of its process specifications and identification (product parameters) is quite important.
The process specifications for this product need to clarify the method of preparation, from the selection of raw materials to the reaction conditions. The raw materials must be pure and fine, and the reaction temperature, pressure, time and other parameters must also be precisely controlled. For example, the ratio of materials should be based on scientific methods, and there should be no difference.
As for the identification (product parameters), the properties, purity, and amount of impurities contained in this product should be clearly marked. Characters such as color, state and taste should be described in detail. The number of purity must be accurate, and the type and content of impurities must not be ambiguous. In this way, the user can understand its nature and quality, and when applying it, it is handy and safe.
Preparation Method
To prepare 5-bromo-2-fluorophenylacetic acid (Benzeneacetic Acid, 5-Bromo-2-Fluoro-), the method is as follows:
Raw materials and production process: Pure bromide, fluoride and phenylacetic acid-related precursors are selected as raw materials. After delicate proportions, the catalytic reaction is carried out at moderate temperature and pressure.
Reaction steps: First, the bromide is co-placed in the reaction kettle with a specific catalyst, and the temperature is slowly heated to a moderate level. When the bromide activity is excited, fluoride is added to promote its precise replacement to form a key intermediate. Then the phenylacetic acid precursor is introduced, and after a series of reactions, the target product is obtained. Crude product.
Purification mechanism: The crude product is purified in multiple steps, removed with a special adsorbent, and then recrystallized to obtain pure 5-bromo-2-fluorophenylacetic acid. The whole process requires strict control of conditions to obtain high-purity products.
Chemical Reactions & Modifications
Taste the wonders of chemistry, endless changes, and the properties of substances can be changed accordingly. Today, when discussing "Benzeneacetic Acid, 5 - Bromo - 2 - Fluoro -", its chemical reaction and modification are worth exploring.
In a chemical reaction, the position of bromine and fluorine affects the molecular activity. Or by means of nucleophilic substitution, bromine or fluorine can be translocated to change its properties. Or on the benzene ring, other groups are introduced to cause changes in the electron cloud, which in turn affects its reactivity.
If modified, it can be hoped to enhance its stability or improve its reaction specificity. If an appropriate catalyst is used to adjust the reaction path, the product of a specific configuration can be generated to meet different needs. This is the unremitting exploration of chemical researchers, hoping to obtain the ideal modification through exquisite reactions, so as to promote the better application of this substance in various fields.
Synonyms & Product Names
There are many names for chemical substances. Today there is Benzeneacetic Acid, 5 - Bromo - 2 - Fluoro - This substance is also known by its similar name and commodity name, which is also investigated by us.
This compound may have another name, and the industry also has different names because of its chemical structure and properties. In various literatures, or see it in books with different names, all want to clarify its essence and facilitate research and communication.
The name of a commodity is also related to market circulation and application. In order to recognize its characteristics or give a unique name, merchants hope to attract attention and stand out from the competition.
Our chemical researchers should scrutinize their similar names and commodity names, distinguish their subtlety, and use the mysteries of chemistry to clarify the properties of substances, hoping to create something, contributing to the chemical industry and benefiting the world.
Safety & Operational Standards
About 5-bromo-2-fluorophenylacetic acid product safety and operating specifications
Fu 5-bromo-2-fluorophenylacetic acid is an important product in chemical research. During its experiment and use, safety and operating standards are of paramount importance and cannot be ignored.
The first word is safety. This product has certain chemical activity or potential harm to the human body. When in contact, it must be fully protected. If the skin touches it, it should be rinsed with a lot of water immediately, followed by a mild soap solution to wash it, so that the residue is not left. If you are not careful to enter the eye, do not panic, rinse it with flowing water continuously, and seek medical attention in time to avoid delay.
As for respiratory protection, in areas with poor ventilation or the risk of volatilization, it is advisable to wear a suitable gas mask to prevent harmful gases from entering the body and damaging the lungs. In addition, storage should also be cautious. It should be placed in a cool, dry and well-ventilated place, away from fire sources and oxidants, to prevent unexpected chemical reactions.
Times and operating specifications. In experimental operation, precise steps must be followed. When measuring this substance, use an accurate measuring tool, and there should be no difference of millimeters. When dissolving, according to its characteristics, choose the appropriate solvent, and add it slowly, while stirring to ensure uniformity. During the reaction process, pay close attention to temperature, pressure and other conditions, and stop immediately if there is any abnormality to check the cause.
Furthermore, when the experimental equipment is used up, it must be washed and dried to prevent the residual 5-bromo-2-fluorophenylacetic acid from affecting the follow-up experiments. Operators should also study relevant knowledge and improve their skills, so that they can use this material properly in a safe and secure environment and achieve the purpose of scientific research. In short, safety and operating standards are the foundation of the use of 5-bromo-2-fluorophenylacetic acid and must not be ignored.
Application Area
Phenylacetic acid, 5-bromo-2-fluorine-this substance has a wide range of application fields. In the field of medicine, it may be a key intermediate for the synthesis of special drugs, assisting in the precise treatment of drugs and healing diseases. In the field of materials science, it can be used as a modifier to optimize material properties and make material properties better, suitable for a variety of scenarios. In the fine chemical industry, it is an important raw material for the preparation of high-end fine chemicals. Through exquisite processes, it produces high-quality products. With its unique chemical structure, this compound shines in various fields and promotes the progress of various industries. It is an indispensable existence in chemical research and production, opening up new paths for many applications and promising unlimited future development potential.
Research & Development
To taste the way of scientific research, the most important thing is to study and develop. Today there is a material name "Benzeneacetic Acid, 5-Bromo-2-Fluoro-", and we are dedicated to studying it.
Initially, explore its physicochemical properties and analyze the wonders of its structure. In the hall of experimentation, repeated trials, observe its response to various things, and observe its signs of change.
Then, seek its development path. Thinking about it in the field of medicine may become a cure for diseases; thinking about it in the field of chemical industry may be a raw material for innovation. Everyone is united, thinking hard, hoping to use this object as a foundation to expand the new realm of scientific research, and to contribute to the development of the industry, so as to reach a high and distant realm and live up to the heart of research.
Toxicity Research
Studies on the toxicity of 5-bromo-2-fluorophenylacetic acid
There are 5-bromo-2-fluorine in the genus of phenylacetic acid, and the study of its toxicity is quite important. Chemical substances have different toxicity, which is related to the health of living beings and the balance of ecology.
5-bromo-2-fluorophenylacetic acid has a unique molecular structure, the position of bromine and fluorine, or the toxic changes. In order to clarify its nature, it should be studied by various methods. Cell experiments can detect its impact on cell growth and metabolism, and animal experiments can know the toxic effects of the body, such as organ damage, abnormal behavior, etc.
And the diffusion of this substance in the environment also needs to be considered. Looking at its degradation, it depends on the existence and change of water, soil and air. If it is very toxic, or it harms the surrounding organisms, it will lead to ecological problems. Therefore, studying its toxicity can be the foundation of protection and governance, ensuring the safety of all things, and avoiding disasters before they occur. This is the heavy responsibility of chemical researchers.
Future Prospects
The future outlook of the husband is of great importance to the research of my chemical products. Today we discuss the product "Benzeneacetic Acid, 5-Bromo-2-Fluoro-".
This product has shown its unique properties in current research. Its molecular structure is exquisite, and the substitution of bromine and fluorine gives it a different chemical activity. Looking to the future, one of them may shine in the field of pharmaceutical synthesis. With its activity, it may become a key intermediate to help the development of new drugs and cure many diseases. Second, in materials science, it is also expected to emerge. With its characteristics, it may be able to optimize material properties, such as improving material stability and changing optical properties.
Although the road ahead is long, we scientific researchers should be passionate and unremitting in our exploration. In time, "Benzeneacetic Acid, 5-Bromo-2-Fluoro-" will surely contribute to the progress of science and the well-being of mankind, create a new situation, and live up to the prospect of the future.
Where to Buy Benzeneacetic Acid, 5-Bromo-2-Fluoro- in China?
As a trusted Benzeneacetic Acid, 5-Bromo-2-Fluoro- manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading Benzeneacetic Acid, 5-Bromo-2-Fluoro- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the physical properties of 5-bromo-2-fluorophenylacetic acid?
5-% -2-deuterium acetic acid is a peculiar compound with a general physical property.
Its outer surface is usually a transparent liquid, which is due to the characteristics of the molecule. The delicate balance of molecular forces makes it possible to aggregate under normal conditions. In terms of its density, normal acetic acid is slightly higher. Due to the large amount of deuterium atoms, the introduction of deuterium atoms into the molecule increases the amount of the whole molecule, so the density increases.
The melting of 5-% -2-deuterium acetic acid also affects normal acetic acid. Its melting temperature is slightly higher, and the presence of deuterium atoms increases the molecular force, so that the molecule requires higher energy to melt in the lattice beam. The boiling temperature also increases, because the melting process needs to overcome more molecular forces, so that more energy is required to make the liquid melt.
In terms of solubility, 5-% -2-deuteroacetic acid has good solubility in water and multi-solution. Due to the fact that the molecule has both low-performance and non-soluble parts, the low-performance carboxyl group can form water molecules and promote its dissolution in water; the non-soluble alkyl part makes it soluble in partial solution, showing a dissolution characteristic similar to that of normal acetic acid.
In addition, the viscosity of 5-% -2-deuteroacetic acid is also slightly higher than that of ordinary acetic acid. Due to the increase in molecular force, the molecular migration needs to overcome greater resistance, resulting in a slight decrease in fluidity and an increase in surface viscosity. In addition, 5-% -2-deuterium acetic acid is subtly and interestingly physical due to the introduction of deuterium atoms, unlike ordinary acetic acid, which is unique.
What are the chemical properties of 5-bromo-2-fluorophenylacetic acid?
5-% hydroxyl-2-pentenedioic acid, this substance has unique chemical properties. It is acidic, because it contains carboxyl groups, it can neutralize with bases. In case of sodium hydroxide, the two combine to form the corresponding carboxylate and water, which is a common case of acid-base neutralization.
has an alkenyl group, which has the ability to add a reaction. If bromine water, the double bond in the alkenyl group breaks, and the bromine atom is added to the carbon at both ends of the double bond, fading the bromine water. This is a typical reaction of alkenes, and the existence of its alkenyl group can be verified.
Because of its hydroxyl group, it can participate in the substitution reaction. When heated with hydrohalic acid, the hydroxyl group can be replaced by a halogen atom to form a halogenated hydrocarbon.
Furthermore, the compound may have certain redox properties. Enyl and hydroxyl groups are both groups that can be oxidized. In case of strong oxidants, such as potassium permanganate, double bonds or hydroxyl groups will be oxidized, resulting in structural changes, and the products vary according to the reaction conditions.
Because of its special structure, it is of great significance in the field of organic synthesis. It can be used as a key intermediate to construct complex organic molecules through various reactions, providing an important basis for the synthesis of new drugs and materials. However, its specific reactivity and selectivity are also influenced by surrounding groups and reaction conditions, such as temperature, solvent, catalyst, etc., which can have a significant impact on the reaction process and product formation.
What are the main uses of 5-bromo-2-fluorophenylacetic acid?
5-% acetyl-2-sialate, the purpose is not good. It is in the realm of, the efficacy is not good. It can help those who make Those who are good at five flavors can use it to make dishes taste better and have a good effect on the body. Or increase the beauty of dishes, or help the digestion of the spleen and stomach, making the body and mind comfortable.
And in the dissolution of poison, 5-%-2-sialate acetyl ester also has amazing properties. In case of poison invasion, it can be introduced by it, and it can be used to detoxify the harm of poison, saving people's lives in critical situations.
Of course, 5-%-2-sialate acetyl ester has a wide range of uses, and can be used for all kinds of things, such as medicine, alchemy, medicine, and solution. It is also a rare good thing.
What are the synthesis methods of 5-bromo-2-fluorophenylacetic acid?
The synthesis method of 5-hydroxyl-2-pentenoic acid includes the following:
First, glutaric anhydride is used as the starting material. Glutaric anhydride is first partially reduced to obtain glutaric acid monoester. A suitable reducing agent can be selected, such as an appropriate amount of lithium aluminum hydride, and the reaction is carefully reacted at a low temperature and in an anhydrous environment. The glutaric acid monoester is then subjected to an intramolecular condensation reaction under the action of a strong base. For example, a strong base of sodium alcohol is heated in an alcohol solution to promote Dieckmann condensation to form a cyclic β-ketoate. After further acidification treatment, β-keto acid ester is converted into β-keto acid, and this β-keto acid is decarboxylated under heating conditions to obtain 5-hydroxyl-2-pentenoic acid. The steps of this pathway are relatively clear, but the control of the reaction conditions is strict, and the yield of each step needs to be carefully regulated.
Second, diethyl malonate and acaldehyde are used as raw materials. Under the action of basic catalysts, the active methylene of diethyl malonate and acaldehyde undergo Michael addition reaction. Commonly used basic catalysts such as sodium alcohol can be added smoothly at appropriate temperatures and solvents. The addition product is hydrolyzed and acidified, and the ester group is converted into a carboxyl group, and the malonic acid structure is decarboxylated. Subsequently, the obtained product is properly oxidized and reduced to obtain 5-hydroxy- 2-pentenoic acid. The raw materials of this method are relatively easy to obtain, but the reaction involves multi-step conversion, and the reaction process needs to be precisely monitored.
Third, ethyl acetoacetate and 3-bromopropylene are used as starting materials. The α-hydrogen of ethyl acetoacetate is in the negative ion state under the action of alkali, and undergoes nucleophilic substitution reaction with 3-bromopropylene. The base can be reacted with potassium carbonate and the like in a suitable solvent. Then, the product is hydrolyzed, acidified and decarboxylated, and then through a suitable hydroxylation reaction, for example, with a suitable oxidant and under specific conditions, a hydroxyl group is introduced, and finally 5-hydroxyl-2-pentenoic acid is obtained. The key to this approach lies in the selectivity of nucleophilic substitution reaction and the optimization of the conditions of subsequent reactions.
What are the precautions for storing and transporting 5-bromo-2-fluorophenylacetic acid?
5-2-pentanedioic acid is also a chemical substance, and it is necessary to pay attention to it when it is not stored.
The first important environment. It should be placed in a place where it is dry and well-connected, to avoid fire and oil sources. This is due to high pollution, or there is a risk of decomposition, reaction, and alteration, which may even endanger safety. If the environment is wet, or there is a reaction such as hydrolysis, its efficiency and efficiency will be compromised.
Furthermore, the container is also compromised. Use compatible materials to prevent corrosion and leakage. Such as glass, specific plastic materials or gold containers, its tolerance must be checked before use to ensure safety. And the container is dense, to prevent the intrusion of air, moisture and other foreign objects.
If there is a problem, the solid package should be properly wrapped with high-quality materials to prevent the container from breaking due to collisions and earthquakes on the way.
In the operation of unloading, it is necessary to be gentle and careful, and it is forbidden to move roughly.
With the same product, the person who needs it will be dangerous. Do not mix with contraindicated substances, such as oxidizer, gluten, etc., because of its strong reaction to 5-2-pentylenedioic acid, and the formation of gluten. And the row, the system, etc., are all good, avoiding danger, Mars, etc.