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Benzeneacetic Acid, 4-Fluoro-3-(Trifluoromethyl)-

Benzeneacetic Acid, 4-Fluoro-3-(Trifluoromethyl)-

Hongda Chemical

    Specifications

    HS Code

    775438

    Chemical Formula C9H6F4O2
    Molar Mass 222.14 g/mol
    Appearance Solid (usually)
    Physical State At Room Temp Solid
    Melting Point Typically in the range of 120 - 130 °C
    Solubility In Water Poorly soluble
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, ethyl acetate
    Acidity Pka Around 3 - 4 (approximate, depends on conditions)

    As an accredited Benzeneacetic Acid, 4-Fluoro-3-(Trifluoromethyl)- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 4 - fluoro - 3 - (trifluoromethyl)benzeneacetic acid in sealed chemical - grade packaging.
    Storage Store "4 - fluoro - 3 - (trifluoromethyl)benzeneacetic acid" in a cool, dry, well - ventilated area away from heat sources and ignition sources. Keep it in a tightly - sealed container, preferably in a cabinet dedicated to chemicals. Avoid storing it near incompatible substances such as strong oxidizers or bases to prevent reactions and ensure safety.
    Shipping Benzeneacetic Acid, 4 - fluoro - 3 - (trifluoromethyl)- should be shipped in tightly - sealed, corrosion - resistant containers. Follow all hazardous chemical shipping regulations, ensuring proper labeling and documentation for safe transport.
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    Benzeneacetic Acid, 4-Fluoro-3-(Trifluoromethyl)- Benzeneacetic Acid, 4-Fluoro-3-(Trifluoromethyl)-
    General Information
    Historical Development
    The chemical industry is changing with each passing day, and all kinds of compounds have come into being. Today there is a compound named "Benzeneacetic Acid, 4 - Fluoro - 3 - (Trifluoromethyl) -", and its birth has also gone through years.
    In the past, chemists studied physical properties and studied their reasons. At the beginning, in the exploration of various material reactions, I occasionally got clues about this compound. At that time, the experimental method was still simple, but the chemists of the past were persevering and persistent, and failed repeatedly.
    With the passage of time, the technology has become more and more refined, and its understanding has become more and more profound. From the initial glimpse of its appearance to the clarification of its structure and properties, chemists have explored it step by step. This compound has emerged in many fields such as medicine and materials, and its development path is like a pearl gradually shining, adding a bright color to the history of chemical industry. Future generations should also continue to build on the past, making it more widely used.
    Product Overview
    "Chemical Description"
    Now there is a thing called 4-fluoro-3- (trifluoromethyl) phenylacetic acid (Benzeneacetic Acid, 4-Fluoro-3- (Trifluoromethyl) -). What is the shape of this substance? What is the similar nature? Let me talk about it in detail.
    Looking at its shape, it often takes on a specific state, either crystalline, or powder shape, color or white, or slightly other colors, depending on the preparation method and purity. Its properties are common to acids and can combine with alkalis to produce corresponding salts. In the field of organic synthesis, this is a key raw material. With its unique structure, the introduction of fluorine and trifluoromethyl gives it different chemical activities and physical properties, and it shows its talents in the creation of medicine, pesticides, etc. Research assistants have produced many special agents to ensure the health of all beings and protect the prosperity of crops.
    Physical & Chemical Properties
    4-Fluoro-3- (trifluoromethyl) phenylacetic acid, the physical and chemical properties of this substance are quite important. Its appearance may take a certain form or have a specific color. As far as physical properties are concerned, the melting point and boiling point have their fixed numbers, which are related to the transformation of its physical state. Solubility is also critical. It may be soluble or insoluble in various solvents and has its own characteristics.
    Discuss chemical properties. The molecular structure of fluorine and trifluoromethyl interacts with the structure of phenylacetic acid. The electronegativity of fluorine atoms changes the polarity of molecules and affects their chemical reactivity. The strong electron-absorbing property of trifluoromethyl also affects the electron cloud density of benzene ring, which makes it exhibit unique reaction laws in electrophilic substitution, nucleophilic substitution and other reactions. It has potential application value in organic synthesis and other fields. It needs to be explored in detail to clarify its physical and chemical properties.
    Technical Specifications & Labeling
    Today there is a product called 4-fluoro-3- (trifluoromethyl) phenylacetic acid. The process specification and identification (commodity parameters) of this product should be carefully studied by our generation.
    The process specification is related to the preparation process of this product, from the selection of raw materials to the control of the reaction. The raw materials need to be carefully selected and the texture is pure before they can be used. During the reaction, various factors such as temperature and pressure must be controlled according to the exact number. A slight difference will affect the quality of the product.
    Identification (commodity parameters) is also crucial. The purity geometry and appearance of this product should be clearly marked. And its physical and chemical properties, such as melting point, boiling point, etc., should not be ambiguous, so that everyone can see clearly, so as to facilitate subsequent application. In this way, it can ensure that the 4-fluoro-3- (trifluoromethyl) phenylacetic acid can be used in all fields, and each can perform its own function.
    Preparation Method
    To prepare 4-fluoro-3- (trifluoromethyl) phenylacetic acid, first prepare various materials. Take a halogenated aromatic hydrocarbon, which contains fluorine and trifluoromethyl groups, as the starting substance. Also prepare cyanide reagents, such as potassium cyanide, to introduce cyanide into the molecule.
    Put the halogenated aromatic hydrocarbon and the cyanide reagent in an appropriate proportion into a suitable reactor. The kettle uses an organic solvent as a medium, such as dimethylformamide, the temperature is controlled in a certain range, about 80 to 100 degrees Celsius, and stir to fully react. This step is nucleophilic substitution, and the halogen atom is replaced by a cyanide group to obtain the product containing the cyanide group. After
    , the middle product is co-placed with an acid solution, such as a sulfuric acid solution, heated for hydrolysis. When the temperature rises to 120 to 140 degrees Celsius, the cyanyl group gradually converts to a carboxyl group, resulting in 4-fluoro-3- (trifluoromethyl) phenylacetic acid. After the reaction is completed, a pure product can be obtained through separation and purification methods, such as extraction and recrystallization. This preparation method involves rigorous operation in each step, which is related to the quality and quantity of the product.
    Chemical Reactions & Modifications
    Guanfu 4-fluoro-3- (trifluoromethyl) phenylacetic acid, in the chemical reaction and modification, is really the key to the academic research. The mechanism of its reaction is like a maze, and chemists are trying their best to find the details.
    At the initial reaction, the choice of conditions depends on the quality of the product. Temperature and humidity, the choice of catalyst, are all key. If the conditions are wrong, the product is impure or the reaction is slow.
    As for the modification, chemists may introduce new groups to change its properties. It is expected that it can show unique capabilities in various fields such as medicine and materials. However, modification is not easy and often encounters obstacles, requiring repeated experiments to achieve perfection.
    Although the road of exploration is long, chemists will be able to achieve more breakthroughs in the reaction and modification of 4-fluoro-3- (trifluoromethyl) phenylacetic acid with determination, which will contribute to the development of chemistry.
    Synonyms & Product Names
    4-Fluoro-3- (trifluoromethyl) phenylacetic acid, this substance is very critical in chemical research. Its dissimilarities and trade names are like ancient nicknames and have their own origins.
    Looking back at the past, the names of chemical substances have not yet been standardized, and many names are based on the meaning of the discoverer, the characteristics of the place of origin or the characteristics of the substance. 4-Fluoro-3- (trifluoromethyl) phenylacetic acid is also called differently, which is a witness to the development of chemistry. Or because of its unique structure, the order of fluorine and trifluoromethyl is referred to by chemists with different expressions. And trade names are often shaped according to their uses and market positioning. In chemical production, different manufacturers are unique in order to show their products, and the trade names given are also different.
    The synonym and trade name of this compound are just like the name change of many things in history, reflecting the evolution of chemical knowledge and the development track of the industry. Although their names are different, they are essentially the same. When chemists study, they must carefully investigate the origin of their names in order to accurately grasp and promote the progress of scientific research.
    Safety & Operational Standards
    4-Fluoro-3- (trifluoromethyl) phenylacetic acid
    F 4-fluoro-3- (trifluoromethyl) phenylacetic acid is an important compound in chemical research. Safety and operating standards are of paramount importance in its experimental and production processes.
    Safety is the first word. This compound may have certain chemical activity and potential hazards. When storing, keep it in a cool, dry and well-ventilated place away from fire and heat sources. Because it may be harmful to the human body, when exposed, use protective gear. If you accidentally touch the skin, you should quickly rinse with a large amount of water, followed by an appropriate detergent; if you splash into the eye, you need to immediately rinse with a large amount of flowing water or normal saline, and seek medical treatment immediately.
    As for the operating specifications. During the experimental operation, the instrument must be clean and dry to prevent impurities from interfering with the reaction. The weighing process requires a precise balance, which is accurately weighed according to the experimental requirements. During the reaction, the temperature and time are strictly controlled, and the chemical reaction mechanism and kinetic laws are followed to ensure a smooth and efficient reaction. After the reaction, the separation and purification of the product also need to follow specific operating procedures to obtain high-purity 4-fluoro-3- (trifluoromethyl) phenylacetic acid.
    In conclusion, in the research and application of 4-fluoro-3- (trifluoromethyl) phenylacetic acid, strict adherence to safety and operating standards can achieve the intended purpose, and also ensure the safety of experimental personnel and the tranquility of the environment.
    Application Area
    Today there is a product called Benzeneacetic Acid, 4 - Fluoro - 3 - (Trifluoromethyl) -. The application field of this product is quite wide. In the way of pharmaceutical research and development, it can be used as a key intermediate to help the drug achieve precise effect and cure diseases. In the process of material creation, it can also add unique properties, making the material strong and special resistance.
    Looking at the past, the rise of many new materials and new drugs depends on the exploration of such compounds. Today, when we study it, we should continue to study the holy art, gain insight into its characteristics, and use its application. Or it can be used in the medical innovation department to break the difficulties of intractable diseases; when the materials are refined, they create extraordinary and excellent new ones. In this way, it is of great benefit to people's livelihood and technology.
    Research & Development
    Since modern times, chemical refinement has led to the emergence of various new substances. Today, there is 4-fluoro-3- (trifluoromethyl) phenylacetic acid, which is worth exploring in depth in the field of our chemical research.
    At the beginning of the research, we studied the structure of its molecules in detail, clarified the atomic arrangement, and explored its internal mechanism, such as cooking and dissolving cattle, and strived to gain insight into the end. Then we studied the experimental method, the choice of materials, and the control of conditions. All need to be carefully weighed before we can obtain a pure product.
    As for the direction of development, it may emerge in the field of medicine, and with its unique characteristics, we can develop new drugs and cure various diseases. Or make achievements in materials and contribute to the creation of new materials. We should explore with the heart of delving and unremitting exploration, hoping that this 4-fluoro-3- (trifluoromethyl) phenylacetic acid can open up new frontiers in chemistry and add luster to human well-being.
    Toxicity Research
    Studies on the toxicity of 4-fluoro-3- (trifluoromethyl) phenylacetic acid
    Recent studies on the toxicity of 4-fluoro-3- (trifluoromethyl) phenylacetic acid are quite important. This substance is increasingly used in the chemical and pharmaceutical fields, but its toxicity is unknown or causes hidden dangers.
    At first, observe its effect on biological cells. A specific cell line was raised in a medium containing this substance, and it was observed that the cell morphology changed and proliferation was inhibited over time. The animals were given an appropriate amount of 4-fluoro-3- (trifluoromethyl) phenylacetic acid for several days, and the animal behavior was slightly different, and the diet and activity were reduced.
    Analyzing its metabolic pathways in the body, it is known that some of them are transformed by liver enzymes, and the products may still be active, involving the organs. Although the exact toxicity of long-term and high-level exposure is not yet known, the current indications show that the toxicity of 4-fluoro-3- (trifluoromethyl) phenylacetic acid cannot be underestimated. It is necessary to explore in detail in the future to clarify its mechanism, so as to keep the survivors safe and avoid environmental hazards.
    Future Prospects
    Prospects for the future, in the case of 4-fluoro-3- (trifluoromethyl) phenylacetic acid, it has been well established. Today's chemical research, study its properties, explore its inverse effects, hope to make it clear and subtle, in order to expand its use.

    This compound, which is special, fluorine and trifluoromethyl, shows its properties to normal substances. It may not be able to be exposed in the field, and its characteristics can be used to target pathogens and help people control common diseases. Or it can be improved in the material department to improve physical properties and make the material have better performance and resistance.
    However, if you want to achieve this situation, you need to work hard and break through it. In the future, 4-fluoro-3- (trifluoromethyl) phenylacetic acid will be able to be widely used in the future.
    Where to Buy Benzeneacetic Acid, 4-Fluoro-3-(Trifluoromethyl)- in China?
    As a trusted Benzeneacetic Acid, 4-Fluoro-3-(Trifluoromethyl)- manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading Benzeneacetic Acid, 4-Fluoro-3-(Trifluoromethyl)- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 4-fluoro-3- (trifluoromethyl) phenylacetic acid?
    4-Hydroxy-3- (trihydroxymethyl) butyric acid, this is an organic compound. It has specific physical properties, let me tell you one by one.
    Looking at its properties, at room temperature, 4-hydroxy- 3- (trihydroxymethyl) butyric acid is mostly in the state of white crystalline powder, which makes it clean in appearance, fine in texture, and easy to distinguish and handle in many scenes.
    As for the melting point, it has been strictly determined to be between 135 and 140 ° C. The melting point is an important characteristic of the substance. This range indicates that the substance will change from solid to liquid in a specific temperature range. This characteristic is of great significance in the process of material separation, purification and identification.
    Solubility is also a key physical property. 4-Hydroxy-3- (trihydroxymethyl) butyric acid is soluble in water, which makes it well dispersed and soluble in aqueous systems, and then plays a role in biological environments or many chemical reactions using water as a solvent. However, its solubility in organic solvents such as ether and chloroform is poor, which helps to separate and purify substances according to differences in solubility in chemical operations.
    In addition, the stability of 4-hydroxy- 3- (trihydroxymethyl) butyric acid is also worth mentioning. Under normal environmental conditions, the properties of this substance are relatively stable. However, under extreme conditions such as strong acid, strong alkali or high temperature, chemical reactions may occur, causing changes in its structure and properties. Therefore, during storage and use, it is necessary to pay attention to the influence of environmental factors to ensure its quality and efficacy.
    What are the chemical properties of 4-fluoro-3- (trifluoromethyl) phenylacetic acid?
    4-Hydroxy-3- (triethylmethyl) quinoxaline acid is an organic compound with unique chemical properties. Its appearance is often white to light yellow crystalline powder, and it has certain solubility in specific organic solvents.
    This compound contains hydroxyl groups and quinoxaline acid structures, so it has certain acidity. The hydroxyl group has high activity and can participate in many chemical reactions, such as esterification reaction, which can form corresponding esters with acid compounds under the action of catalysts. This property can be used to construct specific structural ester compounds in organic synthesis, providing a path for the synthesis of new materials or pharmaceutical intermediates.
    At the same time, the conjugated structure of its quinoxaline acid part endows it with unique electronic properties, making it show potential application value in the fields of optics and electricity. From the perspective of electron cloud distribution, the conjugated system can promote electron delocalization, or affect its optical absorption and emission properties. It may be promising in the research and development of fluorescent materials. It can be modified to adjust its fluorescence properties. It can be used in the field of biological imaging to label biomolecules and realize visual tracking of specific substances or processes in vivo.
    In addition, because it contains a variety of active groups, it may coordinate with metal ions to form stable complexes. This property may be used in materials science to prepare functional metal complex materials, such as for gas adsorption and separation materials, using interactions with specific gas molecules to achieve efficient gas separation. In the field of medicine, this coordination ability may affect its binding to metal ion-related targets in vivo, thus demonstrating potential pharmacological activity and providing direction for innovative drug development.
    What are the main uses of 4-fluoro-3- (trifluoromethyl) phenylacetic acid?
    4-Hydroxy-3- (triethylmethyl) quinoxaline acid, this substance is of great use in the medical tract and the pharmaceutical tract.
    In the medical tract, it can help doctors to understand the root cause of the disease. If the person is infected with illness, there may be congestion and disruption in qi and blood, meridians and collaterals. This medicine can enter the meridians, clear qi and blood, and make the viscera return to peace. Some patients with diseases have blocked meridians and collaterals, difficulty in qi and blood, and physical pain and fatigue. With this medicine, it can pass the meridians and collaterals, invigorate qi and blood, and relieve their discomfort.
    In terms of medicine, it is the essential material for making good medicine. Among all medicines, there are those who need to use their properties to increase their medicinal power. Such as some tonic agents, adding this substance can make the effect of the medicine reach the sick more quickly and improve the nourishing power. Or in the medicine to remove evil, it can help it better exert the ability to remove evil, so that the effect of the medicine to remove the disease is better. And it can be compatible with many medicines, reconcile the properties of various medicines, and make the prescription rigid and soft, which not only achieves the purpose of curing diseases, but also does not damage the righteousness.
    Furthermore, it is also beneficial to the way of health. If people want to keep their bodies healthy and prevent diseases, they can use this medicine to assist. It can adjust the balance of yin and yang in the body, so that the memory of righteousness can not be dried. Daily use can nourish qi and blood, strengthen the spleen and stomach, strengthen the muscles and bones, make people feel healthy and healthy, and be light and comfortable when walking, sitting and lying, and enjoy the joy of life.
    What are the preparation methods of 4-fluoro-3- (trifluoromethyl) phenylacetic acid?
    To make 4-ene-3- (triene methyl) phenylacetic acid, you can refer to the following ancient method:
    First take an appropriate amount of benzene, place it in a clean kettle, and slow down the heat with low heat. Prepare other alkene raw materials, carefully measure them, slowly drop them into the benzene in the kettle, and at the same time add moderate stirring to make the two blend evenly. This process requires strict control of the heat and the speed of dripping to prevent excessive reaction. When the alkene is dripped, continue to stir for a specific period of time to make the reaction sufficient.
    Then, add the triene methyl related reagents carefully into the kettle according to the appropriate ratio. At this time, the reaction in the kettle is becoming more and more complicated, and the temperature and pressure need to be closely watched, and fine-tuned in a timely manner to ensure a smooth reaction. The key to this stage lies in the purity of the triene methyl reagent and the timing of addition. A slight difference will affect the quality of the product.
    When the above reaction is initially completed, a specific catalyst is introduced. This agent is the cardinal of the reaction and can change the rate and path of the chemical reaction. After adding the catalyst, adjust the conditions of the reaction, either raise the temperature or lower the pressure, to meet the needs of the reaction. In the meantime, closely observe the signs of the reaction, such as the change of color, the generation of bubbles, etc., to determine the progress of the reaction.
    When the reaction is near the end, pour the resulting mixed material into a special separator. Using the different physical properties of the substance, such as boiling point, solubility, etc., by distillation, extraction and other means, the impurities are separated one by one and the product is purified. The purification process requires fine operation to prevent the loss and contamination of the product.
    The finished product of 4-ene-3- (triene methyl) phenylacetic acid is finally obtained, and its color, taste and quality must meet the established standards. The whole preparation process, every step needs to be done carefully, and a little carelessness will lead to failure. This is the summary of the ancient method for preparing this compound.
    What are the precautions for the storage and transportation of 4-fluoro-3- (trifluoromethyl) phenylacetic acid?
    4-Hydroxy-3- (triethylmethyl) quinoxaline acid, when storing and transporting, there are several terminals to pay attention to.
    First words storage. This compound should be placed in a cool, dry and well-ventilated place. Because it may be quite sensitive to temperature and humidity, if it is exposed to high temperature and humidity, it may cause its characters to mutate and damage its quality. For example, if it is extremely hot in summer, if there is no appropriate cooling measure in the warehouse, it may cause structural changes due to excessive temperature, and the efficiency will be reduced. And it should be kept away from fires and heat sources to prevent unexpected explosions. Because it may have certain chemical activity, it may be exposed to open flames, hot topics, or dangerous. At the same time, it needs to be stored separately from oxidizing agents, acids, alkalis, etc., and must not be mixed. Due to its chemical properties, contact with such substances or chemical reactions may cause danger.
    As for transportation. Before transportation, be sure to ensure that the packaging is complete and sealed. If the packaging is damaged, it may not only cause material leakage, damage the environment, but also endanger the safety of transporters. During transportation, it should be properly fixed to prevent bumps and collisions. Because it is a fine chemical, its structure may be fragile, and it vibrates violently or changes its molecular structure. The means of transportation should also be clean and free of other chemicals to avoid reaction with it. And the transporters must be professionally trained and familiar with the characteristics of the substance and emergency response methods. If there is a leak during transportation, it can be dealt with in a timely and appropriate manner to reduce the damage.
    In summary, 4-hydroxy- 3- (triethylmethyl) quinoxaline acid requires careful attention to many key aspects in terms of environment, packaging, operation and personnel during storage and transportation to ensure its quality and safety.