Hongda Chemical
Products
Home  /  Products  / 

Benzeneacetic Acid, 4-Fluoro-3-Nitro-

Benzeneacetic Acid, 4-Fluoro-3-Nitro-

Hongda Chemical

Specifications

HS Code

681447

Chemical Formula C8H6FNO4
Molecular Weight 199.14
Appearance Solid
Melting Point Data needed
Boiling Point Data needed
Density Data needed
Solubility In Water Low
Solubility In Organic Solvents Soluble in some organic solvents
Pka Data needed
Flash Point Data needed

As an accredited Benzeneacetic Acid, 4-Fluoro-3-Nitro- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 4 - fluoro - 3 - nitro - benzeneacetic acid in sealed chemical - grade packaging.
Storage Store "4 - fluoro - 3 - nitro - benzeneacetic acid" in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly - sealed container to prevent moisture absorption and evaporation. As it is a chemical, store it separately from incompatible substances like oxidizing agents and bases to avoid potential reactions.
Shipping 4 - fluoro - 3 - nitro - benzeneacetic acid is shipped in properly sealed containers, following strict chemical transport regulations. Containers are designed to prevent leakage, ensuring safe transit to destination.
Free Quote

Competitive Benzeneacetic Acid, 4-Fluoro-3-Nitro- prices that fit your budget—flexible terms and customized quotes for every order.

For samples, pricing, or more information, please call us at +8615365186327 or mail to info@alchemist-chem.com.

We will respond to you as soon as possible.

Tel: +8615365186327

Email: info@alchemist-chem.com

Benzeneacetic Acid, 4-Fluoro-3-Nitro- Benzeneacetic Acid, 4-Fluoro-3-Nitro-
General Information
Historical Development
Although the historical development of 4-fluoro-3-nitrophenylacetic acid is unknown in ancient times, the road of chemical evolution has gradually been studied. In the past, chemistry was not yet prosperous, and material exploration was not in depth. After the advance of science, the art of analysis gradually refined.
At the beginning, people's understanding of the chemical structure was still shallow, and the characteristics of the compound were also unknown. With the improvement of experiments, researchers began to investigate its molecular composition, and it was clear that 4-fluoro-3-nitrophenylacetic acid has unique properties.
After many experiments, we know the method of its synthesis, and the reaction conditions and the proportion of raw materials have been studied. And its use in medicine, materials and other fields has gradually become known. With the passage of time, its research has continued to deepen and its application has become more extensive, leaving a unique track in the course of scientific development.
Product Overview
Today, there is a substance called Benzeneacetic Acid (Benzeneacetic Acid, 4 - Fluoro - 3 - Nitro -). Its shape is also crystalline, and its color state is pure. This substance is quite important in the field of organic synthesis.
Looking at its structure, above the benzene ring, fluorine and nitro are on one side, and the side is connected by an acetic acid group. This arrangement gives it its unique properties. Nitro has the ability to absorb strong electrons, causing the electron cloud density of the benzene ring to change, which affects its chemical activity. The introduction of fluorine atoms also changes its physical and chemical properties.
In the reaction, 4-fluoro-3-nitrophenylacetic acid can be used as a key raw material. After various chemical transformations, various valuable products can be generated. Whether it involves nucleophilic substitution or redox, it depends on its structural characteristics. In the industry of organic synthesis, it is an indispensable material, helping researchers explore the unknown and create new products. It is expected to be used in many fields such as medicine and materials.
Physical & Chemical Properties
4-Fluoro-3-nitrophenylacetic acid, the physical and chemical properties of this substance are related to many aspects. Its appearance may be in a specific color state, such as powder or crystal. Melting point and boiling point are also important physical properties, which determine its morphological transformation at different temperatures. In terms of solubility, it may be soluble in a specific solvent, but not in others, which is related to its dispersion and participation in the reaction system.
In terms of chemical properties, it has unique reactivity because it contains fluorine, nitro and carboxyl groups and other functional groups. The strong electron absorption of nitro groups changes the electron cloud density of the benzene ring, which affects the check point and activity of electrophilic substitution reactions. Carboxyl groups are acidic and can neutralize with bases. The introduction of fluorine atoms, or enhance its stability, also affects the intermolecular force, and has an effect on its melting point, boiling point, solubility and other physical and chemical properties, which is of great significance in many chemical synthesis and application fields.
Technical Specifications & Labeling
Nowadays, the name of the substance is 4-fluoro-3-nitrophenylacetic acid (Benzeneacetic Acid, 4-Fluoro-3-Nitro -), and its process specifications and identification (product parameters) are the key. To clarify its process specifications, it is necessary to consider the preparation method in detail. From the selection of raw materials, it is necessary to be pure and free of impurities, and the reaction conditions, such as temperature, pressure, and catalyst dosage, need to be precisely controlled. The reaction time should not be ignored to ensure that the reaction is complete.
When it comes to labeling, the name, chemical formula, and product parameters, such as purity geometry and impurity content, should be clearly marked. In this way, the process specifications and labels of this object can be standardized, which is beneficial to the user and conducive to the smooth operation of business.
Preparation Method
The method of making 4-fluoro-3-nitrophenylacetic acid is related to the raw materials and production process, reaction steps and catalytic mechanism. The first raw materials are fluorobenzene, nitric acid, acetic anhydride, etc. Fluorobenzene is used as a group, mixed with nitric acid and sulfuric acid, and the temperature is controlled at about 50 to 60 degrees Celsius. The nitration reaction is carried out to obtain 3-nitrofluorobenzene.
Then, 3-nitrofluorobenzene and acetic anhydride are heated to 100 to 120 degrees Celsius in an appropriate solvent under the action of a catalyst. After the hydrolysis step, the intermediate product is hydrolyzed with alkali solution, the pH value is adjusted, and 4-fluoro-3-nitrophenylacetic acid is precipitated. In this process, the catalyst is selected from metal salts, which can promote the reaction to proceed efficiently. In this way, following these steps, 4-fluoro-3-nitrophenylacetic acid can be prepared.
Chemical Reactions & Modifications
Nowadays, there is a chemical substance called 4-fluoro-3-nitrophenylacetic acid (Benzeneacetic Acid, 4-Fluoro-3-Nitro -), and its chemical reaction and modification are quite important to our chemical researchers.
The reaction of this substance is related to the mechanism of chemistry, and there are subtle laws between changes. To find a way to modify it, it is necessary to understand the structure of its molecules and explore the relationship between its atoms. After repeated experiments, observe its reaction under different conditions, or when exposed to heat, or when exposed to specific reagents, observe its changes.
Modification methods aim to optimize its properties, or increase its stability, or change its activity. By chemical methods, adjust its structure, so that it can be applied to a wider range of fields. Such as medicine, materials, etc., are expected to use its modification to achieve better results. We should study diligently, use scientific methods to understand the principle of its reaction, and seek the best solutions for its modification, so as to contribute to the development of chemistry.
Synonyms & Product Names
Phenylacetic acid, 4-fluoro-3-nitro, is the same quality in the process. Although its names are different, the synonyms and trade names are also important for research. The name of the cover is synonymous, or it is derived from its nature and structure, which can help us understand this thing deeply. The trade name is related to the market, and each business may give it a different name, in recognition of its unique product.
When studying this thing, the synonymous names such as aliases, used names, etc., should be carefully examined. Aliases or names are named according to their particularity, and used names remember their past titles, which can give a glimpse of their research process. And the trade name, the merchant stands according to its use and quality, to attract people's attention.
Our chemical researchers must carefully study the synonyms and trade names of phenylacetic acid, 4-fluoro-3-nitro, in order to be smooth in the research, clear in the trade, and not confused.
Safety & Operational Standards
About 4-fluoro-3-nitrophenylacetic acid Product Safety and Operating Specifications
4-fluoro-3-nitrophenylacetic acid, the genus of chemical products. Its preparation, use and storage links, strictly abide by safety and operating standards, to ensure all things go smoothly and avoid disasters.
When preparing, all reagents and instruments must be clean and stain-free. When taking the reactants, measure them with a scale and a gauge according to the exact amount, and do not make a slight difference. The temperature and pressure of the reaction environment must also be carefully controlled. If the temperature is high, the reaction will be too fast, or dangerous; if the temperature is low, the reaction will be slow, which will affect the yield. The reaction device should be stable and safe, and have corresponding condensation, reflux, and exhaust gas treatment equipment. The exhaust gas, or contains harmful gases, should not be allowed to escape into the atmosphere, so as not to pollute the environment and harm life.
When using, the operator must wear protective gear. Protective clothing can resist the erosion of chemicals on the skin; goggles can protect the eyes from splashing liquid; masks filter out harmful particles and gases in the air. Operation should be in a well-ventilated place. If conditions permit, use a fume hood. This can quickly discharge harmful gases and reduce the concentration of harmful substances in the air.
When storing, 4-fluoro-3-nitrophenylacetic acid should be kept in a cool, dry place away from direct sunlight. Cover with light, high temperature or promote its decomposition and deterioration. And should be placed separately from oxidizing agents, reducing agents, acids, alkalis, etc., to prevent interaction and cause danger. Storage containers must be well sealed to prevent leakage. And on the container, state its name, characteristics, hazards and emergency treatment methods for easy identification.
If there is a leak, emergency measures should be taken immediately. Small leaks can be covered and sucked with inert materials such as sand and vermiculite, and properly disposed of after collection. If there is a large leak, the surrounding crowd should be evacuated immediately, and warning signs should be set up to prohibit unrelated persons from approaching. Disposal personnel must wear professional protective equipment and use suitable equipment to collect leaks and deal with them in accordance with relevant regulations.
In short, the safety and operating standards of 4-fluoro-3-nitrophenylacetic acid should not be slack. Act with caution and strictly abide by the procedures to ensure the safety of chemical research and production, and also protect the natural environment and human health.
Application Area
Guanfu phenylacetic acid, 4-fluoro-3-nitro, has a wide range of application fields. In the field of medicine, it can be used as a key intermediate to help synthesize specific drugs and cure various diseases. In the field of agriculture, it can be used to create high-efficiency pesticide raw materials, protect crops, and drive away pests and diseases. In the field of materials science, it can be specially treated to participate in the construction of novel functional materials, making them have specific properties, such as unique optical and electrical properties. Its multi-purpose, is actually an ingredient that cannot be underestimated in chemical research and industrial development, can exert its strengths in many fields, contribute to human life and scientific and technological progress, and lead many new applications.
Research & Development
I have been researching chemical products for a long time, and recently focused on the research of 4-fluoro-3-nitrophenylacetic acid. This product is also unique and has potential uses in many fields.
At the beginning of the research, study its structure in detail, explore the secret of its molecules, clarify the method of atomic bonding, and know its electron distribution state. Also observe its physical and chemical properties, measure its degree of melting, observe its dissolution, and understand its behavior in different media.
Then study its synthesis method, try various paths, choose the best and eliminate the bad. Improve the old method, innovate ideas, and hope to get an efficient and green synthesis. During this period, I encountered all kinds of problems, or the response was slow, or the yield was not as expected, but I tried my best to solve them.
Looking at its development now, the prospects are quite good. In the field of medicine, it may be used as a key intermediate to assist in the research of new drugs; in terms of materials, it is also expected to give new capabilities to materials. I should make unremitting efforts to cultivate this field and promote its development. I hope to achieve success and contribute to the progress of chemistry.
Toxicity Research
The toxicity of phenylacetic acid, 4-fluoro-3-nitro, is related to all living beings and cannot be ignored. Observe the nature of this thing, or enter the body and disturb the peace of the internal organs. Test it with the ancient method, take all insects and livestock, apply this thing, and observe its appearance. See insects or stiff, livestock or impatient, even fatal. This shows that its toxicity is so strong that it is very harmful to living beings. It may damage the function of the internal organs and disrupt the movement of qi and blood. If people touch it, they are also afraid of illness. Therefore, when studying the toxicity of this thing, we must be careful and understand its harm, so as to prevent man-made disasters and keep all things peaceful.
Future Prospects
In the future, 4-fluoro-3-nitrophenylacetic acid is an important material. Today's science and technology is changing day by day, and researchers hope that it can be used in the field of science and technology, and has extraordinary benefits. Or it can help research new technologies, anti-disease, so that people can avoid the pain of disease.
And the chemical industry, also hope that it will become a code of efficient synthesis. The method of precision, increase its efficiency, reduce its cost, and make the production more reasonable.
Furthermore, under the consideration of protection, research its color process, reduce pollution, and reduce pollution is the way to go. In this way, 4-fluoro-3-nitrophenylacetic acid will be able to make a splendor in the future, use it in the world, create a blessing for the people, and achieve a brilliant work.
Where to Buy Benzeneacetic Acid, 4-Fluoro-3-Nitro- in China?
As a trusted Benzeneacetic Acid, 4-Fluoro-3-Nitro- manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading Benzeneacetic Acid, 4-Fluoro-3-Nitro- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of 4-fluoro-3-nitrophenylacetic acid?
4-Hydroxy-3-methoxyphenylacetic acid is an organic compound. It is weakly acidic, and because it contains a carboxyl group (-COOH), the carboxyl group can release protons, which is acidic in aqueous solutions.
Its physical properties, under room temperature, or white to light yellow crystalline powder, have a certain melting point and boiling point, which are determined by the intermolecular forces. The melting point is the temperature at which the substance changes from solid to liquid, and the boiling point is the temperature at which the liquid state changes to gas state. These two can help us distinguish its purity and characteristics.
In terms of solubility, it is slightly soluble in water, but in organic solvents such as ethanol and ether, the solubility is higher. This is due to the principle of similar miscibility. The molecules have a certain polarity and are similar to the polarity of organic solvents, so they can be miscible with each other.
In terms of chemical activity, the carboxyl group can neutralize with the base to generate the corresponding salt and water. And because there are hydroxyl and methoxy groups on the benzene ring, which are the power supply groups, which can increase the electron cloud density of the benzene ring, and make the benzene ring more prone to electrophilic substitution reactions, such as halogenation, nitrification, sulfonation, etc.
Hydroxy (-OH) can also participate in many reactions, such as esterification with acids to form ester compounds. This reaction often requires a catalyst and suitable reaction conditions. Although the methoxy group (-OCH) is relatively stable, it can also participate in the reaction under specific conditions and affect the chemical behavior of the molecule. In conclusion, the chemical properties of 4-hydroxy-3-methoxyphenylacetic acid are determined by its functional groups and molecular structures, and have important research and application value in the fields of organic synthesis and medicinal chemistry.
What are the physical properties of 4-fluoro-3-nitrophenylacetic acid?
4-Hydroxy-3-methoxyphenylglycolic acid, also known as vanilmandelic acid, is a white crystalline powder. Its melting point is about 126-129 ° C, slightly soluble in water, soluble in ethanol and acetone.
This substance is prone to decomposition under light and has poor stability. It has a certain acidity, which is due to the carboxyl group in its structure. In the field of organic synthesis, 4-hydroxy-3-methoxyphenylglycolic acid can be used as a key intermediate for the synthesis of many bioactive compounds.
In the field of medical testing, it is of great significance and is one of the important products of catecholamine metabolism. By detecting the content of 4-hydroxy- 3-methoxyphenylglycolic acid in human urine, it can assist in the diagnosis of endocrine diseases such as pheochromocytoma. Because pheochromocytoma can cause abnormal increase in the secretion of catecholamines in the body, which in turn increases the content of this metabolite in the urine.
In the field of analytical chemistry, in view of its physical and chemical properties, it can be accurately quantified and qualitative analyzed by high performance liquid chromatography, mass spectrometry and other means. With its absorption characteristics at specific wavelengths, its content can also be determined by ultraviolet-visible spectrophotometry.
What are the common uses of 4-fluoro-3-nitrophenylacetic acid?
4-N-3-methoxyphenylacetamide is commonly used. It can be used in the process of synthesis, and it plays an important role in the research of some painkillers. Due to its unique properties, it can be used for specific reactions, helping to build molecules with painkillers.
In the field of biological and chemical research, it also has its own impact. It can be used as a tool to explore the cellular pathway. Because it can affect the biochemical reactions of the cellular parts due to the interaction of certain receptors or enzymes, it can help researchers gain insight into the physiological system.
Furthermore, in the field of materials science, it also has certain uses. Or it can be used for the production of some special materials, through chemical repair and other means, so that the materials can obtain specific properties, such as improving the biocompatibility of materials.
It is also useful in the field of fragrance. Because it has a special flavor, it can be used in processes such as lifting and blending. It is used in fragrance formulations to add special flavor and rich fragrance.
Therefore, 4-methoxy-3-phenylacetamide, by virtue of its chemical properties, plays an indispensable role in many fields such as medicine, scientific research, materials and fragrances.
What are the synthesis methods of 4-fluoro-3-nitrophenylacetic acid?
4-Hydroxy-3-methoxyphenylacetic acid, an organic compound, is widely used in medicine, chemical industry and other fields. There are many synthesis methods, the following are the common ones:
1. ** Using vanillin as the starting material **: Vanillin can be prepared from 4-hydroxy-3-methoxyphenylacetic acid through a series of reactions. First, vanillin and malonic acid are condensed by Knoevenagel in the presence of basic catalysts such as pyridine to generate 4-hydroxy-3-methoxycinnamic acid. Subsequently, 4-hydroxy-3-methoxycinnamic acid is catalyzed by hydrogenation in a hydrogen atmosphere under the action of suitable catalysts such as palladium carbon, and the double bond is hydrogenated and reduced to obtain 4-hydroxy-3-methoxyphenylacetic acid. The raw materials for this route are easy to obtain, and the reaction conditions of each step are relatively mild. It is commonly used in laboratories and industrial production.
2. ** Using p-hydroxybenzaldehyde as the starting material **: p-hydroxybenzaldehyde is first methylated, and the phenolic hydroxyl is methylated under basic conditions with methylation reagents such as dimethyl sulfate to generate 4-methoxybenzaldehyde. Then, 4-methoxybenzaldehyde reacts with diethyl malonate under the action of alkaline catalysts such as sodium ethanol to form the corresponding diethyl malonate derivative. After that, the derivative can be hydrolyzed and decarboxylated to obtain 4-hydroxy-3-methoxyphenylacetic acid. This method has a little more steps, but the raw materials are widely sourced, and the reaction selectivity of each step is good. The yield can be improved by optimizing the reaction conditions.
3. ** Direct construction method of benzene ring **: With appropriate phenols, alaldehyde and carboxyl-containing compounds as raw materials, under specific catalyst and reaction conditions, the benzene ring is directly constructed and the desired substituent is introduced. For example, using strategies such as transition metal-catalyzed cross-coupling reactions, small molecules with different functionalizations are connected through chemical bonds to construct the target molecular structure. Although this method is challenging, it provides a new path for the synthesis of such compounds, which is expected to simplify the synthesis process and improve the atomic economy. It is one of the current research hotspots in the field of organic synthesis.
When synthesizing 4-hydroxy-3-methoxyphenylacetic acid, it is necessary to carefully select the appropriate synthesis method according to many factors such as actual demand, raw material availability, cost and reaction conditions, in order to achieve the synthesis goals of high efficiency, economy and environmental protection.
What are the precautions for 4-fluoro-3-nitrophenylacetic acid in storage and transportation?
4-Hydroxy-3-aminoacetophenone acid is a precious organic compound. During storage and transportation, many points need to be paid attention to:
First, when storing, choose a dry, cool and well-ventilated place. This compound is easily affected by humidity. If the environment is humid, or it causes deliquescence and deterioration, it is necessary to ensure that the storage environment is dry. The temperature should not be too high, high temperature or cause its chemical reaction, which will damage the quality. Usually a refrigerated environment of 2-8 ° C is appropriate, which can effectively extend its shelf life.
Second, during transportation, be sure to take protective measures. Due to its nature or more active, vibration and collision may cause accidents. The packaging needs to be stable and solid to cushion the impact force generated during transportation. And it should be avoided to mix with oxidizing agents, acids, alkalis and other substances, because these substances come into contact with them or undergo violent chemical reactions, endangering transportation safety.
Furthermore, whether it is a storage container or a transportation vehicle, it must be clean and pollution-free. Minor impurities may also affect 4-hydroxy-3-aminophenylacetophenone acid, causing its purity to decrease, which in turn affects the subsequent use effect. The material of the container used must also be carefully selected. Generally speaking, glass or specific plastic materials are more suitable because of their relatively stable chemical properties and are not easy to react with compounds.
In addition, relevant regulations and standards should be strictly followed regardless of storage or transportation. Operators must be professionally trained and familiar with the characteristics and safety precautions of the compound, so as to ensure the safety and stability of 4-hydroxy-3-aminophenylacetophenone acid during storage and transportation.