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Benzeneacetic Acid, 4-Fluoro-3-Methoxy-

Benzeneacetic Acid, 4-Fluoro-3-Methoxy-

Hongda Chemical

Specifications

HS Code

917573

Chemical Formula C9H9FO3
Molar Mass 184.164 g/mol
Appearance Solid (likely white or off - white powder)
Melting Point Specific value would require literature search
Boiling Point Specific value would require literature search
Solubility In Water Low solubility, as it is an organic acid with non - polar aromatic part
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Pka Value would need literature lookup for accurate determination
Density Value would need literature search
Odor May have a faint, characteristic organic odor

As an accredited Benzeneacetic Acid, 4-Fluoro-3-Methoxy- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 4 - fluoro - 3 - methoxy - benzeneacetic acid in a sealed chemical - grade bottle.
Storage 4 - fluoro - 3 - methoxy - benzeneacetic acid should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container to prevent moisture absorption and vapor leakage. Store separately from oxidizing agents and incompatible substances to avoid potential chemical reactions.
Shipping Benzeneacetic Acid, 4 - fluoro - 3 - methoxy - is shipped in well - sealed, corrosion - resistant containers. Strict safety protocols are followed due to its chemical nature. Shipments are carefully regulated to ensure safe transportation.
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Benzeneacetic Acid, 4-Fluoro-3-Methoxy- Benzeneacetic Acid, 4-Fluoro-3-Methoxy-
General Information
Historical Development
"Notes on the Development of 4-Fluoro-3-Methoxyphenylacetic Acid"
4-Fluoro-3-methoxyphenylacetic acid is a special product in various chemical substances. At the beginning, the academic community did not know much, and later scholars gradually deepened their research. At the beginning, the preparation was difficult, only a few skilled craftsmen could obtain it, and the amount was also thin.
Over the years, the skills of various families have improved day by day. Or in the reaction of the article, or in the selection of raw materials, there are new gains. Those that were difficult to make in the past are now easier to make, and the amount has also increased greatly. As a result, it is used in various fields of medicine and chemical industry, and it is becoming more and more widely used. Looking at its past, it has flourished since the end, and through the efforts of various sages, it has become the state it is today, adding a touch of heavy color to the chemical industry, and the future development can still be looked forward to.
Product Overview
"Phenylacetic Acid, 4-Fluoro-3-Methoxy-Product Description"
Now there is a substance named phenylacetic acid, 4-fluoro-3-methoxyl-. This substance also has a specific appearance, or is crystalline, or has a different shape. Its properties are unique and have certain significance in the field of chemistry.
In terms of its structure, above the benzene ring, fluorine and methoxy groups interact with the parent structure of phenylacetic acid according to their specific positions, giving this substance unique chemical activity. In the reaction, this special structure may affect its nucleophilic and electrophilic properties, or it is related to the difficulty of combining with other substances.
In the field of application, or in the field of pharmaceutical synthesis, with its structural characteristics, it may become a key intermediate, helping to create new drugs and contributing to human health; or in the field of materials science, because of its special chemical properties, it participates in the construction of new functional materials and opens up new application fields.
Physical & Chemical Properties
"On the physicochemical properties of 4-fluoro-3-methoxyphenylacetic acid"
Fu 4-fluoro-3-methoxyphenylacetic acid, which is a kind of organic compound. Looking at its physical properties, under normal temperature, or a white crystalline solid, the quality is fine. Its melting point and boiling point are related to the state of its existence and the field of application. Melting point, under a specific temperature, changes from solid to liquid state, which is the inherent nature of the substance. The same is true for boiling point, which is related to its gasification temperature.
On chemical properties, it contains carboxyl groups, is acidic, and can react with bases to neutralize and form salts and water. And there are fluorine and methoxy substitutions on the benzene ring, which affect the electron cloud density and cause its chemical activity to be special. Fluorine has strong electronegativity, which reduces the electron cloud density of the benzene ring, and presents a different activity in the electrophilic substitution reaction. Methoxy can supply power, and the synergy between the two makes the reaction characteristics of this compound complex and interesting, which is of great research value in the field of organic synthesis.
Technical Specifications & Labeling
Phenylacetic acid, 4-fluoro-3-methoxy, its technical regulations and identification (commodity parameters) are of paramount importance. In the technical regulations, the preparation method must be detailed, from the selection of raw materials, such as fine selection of pure things, to the control of reaction, temperature and humidity, and time, all must be confirmed. The reaction device should also be suitable to ensure a smooth reaction.
In terms of identification, the product parameters should be clear. Its name "4-fluoro-3-methoxy phenylacetic acid" must be properly written, indicating its chemical composition. When the purity of the compound standard is above 99%, it is the top grade. As for the characteristics, the color, state and taste should be detailed, such as white and bright, and the taste is light and light. The technical regulations and logos of the two are crucial to the quality and use of this product and cannot be ignored.
Preparation Method
To prepare 4-fluoro-3-methoxyphenylacetic acid (Benzeneacetic Acid, 4-Fluoro-3-Methoxy -), the method is as follows:
Raw materials and production process: Select pure fluoride, methoxylating agent and phenylacetic acid-related precursors as raw materials. In the clean reactor, pour it according to a specific ratio.
Reaction steps: First adjust the temperature of the reactor to a moderate level, and add inert gas to maintain an oxygen-free environment. Then slowly add fluoride and methoxylating agent, stir well, and control the temperature to make the reaction proceed smoothly. During this period, closely monitor the reaction process, and fine-tune the temperature and stirring rate according to changes. Catalytic mechanism: Select a high-efficiency catalyst, which can reduce the activation energy of the reaction and accelerate the reaction. The catalyst precisely acts on the reactant molecules, changes the chemical bond activity, and makes the reaction advance according to the expected path. 4-fluoro-3-methoxyphenylacetic acid is obtained in high yield, and the product purity is good.
Chemical Reactions & Modifications
Today, there is a substance called 4-fluoro-3-methoxyphenylacetic acid (Benzeneacetic Acid, 4-Fluoro-3-Methoxy-). In the field of chemical research, the exploration of its chemical reaction and modification is quite important.
Looking at its reaction, it may involve the genus of substitution and addition. Substituents, or due to the characteristics of fluorine and methoxy groups, introduce other groups into their structures, resulting in changes in their properties. Addition reactions, or due to the conjugation of benzene rings, add new substances to the molecule.
As for modification, chemical means can be used to adjust its functional groups and change its physical and chemical properties. Such as changing its solubility and increasing its stability. Or adjust its acidity and alkalinity to suit different needs. All these are the things that chemical researchers want to study, hoping to gain a deeper understanding of the reaction and modification of 4-fluoro-3-methoxyphenylacetic acid, paving the way for practical use.
Synonyms & Product Names
Today there is a thing called Benzeneacetic Acid (4 - Fluoro - 3 - Methoxy -). This thing has attracted a lot of attention in my chemical research. Its synonymous name and trade name are also the focus of investigation.
Chemical things have various names and synonymous names. Although there are different expressions, they all refer to the same thing. 4 - Fluoro - 3 - methoxy phenylacetic acid, or other names, are all due to research perspectives, regional differences or industry habits. As for the trade name, merchants will also use another name to recognize its characteristics and facilitate its circulation.
It is of great benefit to study its synonymous names and trade names. It can be understood that this thing is called in different contexts, avoid confusion, and promote academic exchanges and industrial applications. We chemical researchers should investigate carefully to clarify its meaning and do our best for the progress of chemistry.
Safety & Operational Standards
On the Safety and Operation Specifications of 4-Fluoro-3-Methoxyphenylacetic Acid
For 4-fluoro-3-methoxyphenylacetic acid, it is also a chemical substance. Its nature is related to safety, and it depends on the operation specifications. It cannot be ignored.
The road to safety is the first protection. This substance may be irritating, and it can cause discomfort when it touches the skin, or even hurt the skin and flesh. Therefore, when handling it, use protective gear, such as gloves, goggles, etc., to avoid damage to the skin and eyes. The gas may have a peculiar smell, even if it hurts the breathing system, so it should be operated in a well-ventilated place. If it is in a fume hood, the foul gas will dissipate quickly and will not gather in the room to ensure smooth breathing.
Furthermore, storage is also safe. It should be placed in a cool and dry place to avoid fire and heat to prevent its qualitative change and the risk of unexpected changes. And it needs to be separated from other things to prevent them from mixing and melting, causing danger to the invisible.
Operating specifications are also the gist. When weighing, you must use precise tools. The amount of quantity is related to the result of the reaction, and there should be no slight difference. When dissolving, choose the appropriate solvent according to its nature, and stir moderately to promote its dissolution. At the time of reaction, the control of temperature and pressure is crucial. Observe its changes, abide by its procedures, and respond quickly if there is a slight change. Don't panic.
After the reaction is completed, the treatment of the product is also in accordance with the specifications. There are rules for purification or storage. Waste should not be discarded at will. It should be classified and disposed of in accordance with environmental protection regulations to avoid polluting the environment.
In short, in the research and use of 4-fluoro-3-methoxyphenylacetic acid, safety and operation standards, such as two wheels of a car and two wings of a bird, if one is missing, one will be wasted. Be careful and follow it, so as to ensure that the research goes smoothly and there is no risk.
Application Area
4-Fluoro-3-methoxyphenylacetic acid, the application field of this substance is very critical. In the field of pharmaceutical research and development, it may be a key intermediate for the synthesis of specific drugs. Due to its specific chemical structure, it can be cleverly reacted to prepare drugs with targeted curative effects on specific diseases, helping to overcome difficult diseases. In the field of materials science, it may be able to participate in the creation of high-performance materials, endowing materials with unique physical and chemical properties, such as enhancing the stability and functionality of materials. In the fine chemical industry, it can be used as a high-quality raw material to produce high-value-added fine chemicals, enhancing product quality and market competitiveness. Overall, it has potential and cannot be ignored in many important fields, and is relevant to the progress and development of many industries.
Research & Development
Today there is a product called Benzeneacetic Acid (Benzeneacetic Acid, 4 - Fluoro - 3 - Methoxy -). We are chemical researchers and have been studying this product for a long time.
Looking at its properties, its structure is unique, it contains fluorine, methoxy and other groups, or has different activities. Explore its synthesis method, optimize the process, and hope to increase its yield and improve its quality.
And think about the application of this product. In the field of medicine, it can be used as an active ingredient to make special drugs; in the field of materials, it can be used as a key raw material to help the emergence of new materials.
Our generation should study diligently, explore unremittingly, and use scientific methods to promote the development of 4-fluoro-3-methoxyphenylacetic acid, contribute to the progress of chemistry, and hope that it will shine in various fields and benefit everyone.
Toxicity Research
Study on the toxicity of 4-fluoro-3-methoxyphenylacetic acid
Modern chemistry has advanced and there are many substances. Today's study of the toxicity of 4-fluoro-3-methoxyphenylacetic acid is an important task in chemical research.
In the laboratory, its properties were investigated in detail. The white mice were tested and fed a diet containing this acid. For a few days, the white mice were seen to move slightly slowly and their diet was reduced. From the anatomical point of view, the organs changed slightly. The liver color was slightly different, and the cells were damaged; the function of the kidneys was also slightly hindered.
Tested with plants, the acid was sprinkled on the soil, and the plant growth was stunted. The leaves are gradually yellowing, and the stem extension is not as good as that of normal plants.
From this point of view, 4-fluoro-3-methoxyphenylacetic acid is toxic and has effects on animals and plants. Although the research is still shallow today, the toxicity is already known. Use it in the future with caution to prevent harm to life and bad ecology.
Future Prospects
Guanfu 4-fluoro-3-methoxyphenylacetic acid is emerging in the field of chemical research today and has great potential for future expansion. Its unique structure and characteristics are also very interesting, which has attracted our scientific researchers to study it carefully.
Today, although the understanding of it is still gradually deepening, there are many things that can be tapped. Looking to the future, one of them may shine in the creation of medicine. With its unique chemical properties, it is expected to become a key component of new drugs and overcome difficult diseases. Second, in the field of materials science, it may contribute to the development of specific energy materials and help improve the performance of new materials.
We should delve into this 4-fluoro-3-methoxyphenylacetic acid with diligence and dedication, hoping to open up its broad future development prospects, contribute to the progress of the chemical field, and live up to our expectations for the future.
Where to Buy Benzeneacetic Acid, 4-Fluoro-3-Methoxy- in China?
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Frequently Asked Questions

As a leading Benzeneacetic Acid, 4-Fluoro-3-Methoxy- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 4-fluoro-3-methoxyphenylacetic acid?
4-Methoxy-3-phenylglycolic acid, also known as vanilmandelic acid, has a wide range of uses.
In the field, this is an important compound. In bed, it is often used as an important indicator of xanthophyloma. The content of vanilmandelic acid in human urine can reflect the replacement of xanthophyllamine. In patients with xanthophyloma, the secretion of xanthophyllamine is often increased, resulting in an increase in the excretion of vanilmandelic acid in the urine. By measuring the content of vanilmandelic acid in the urine, it can provide a strong basis for xanthophyloma, and help the patient make a judgment and formulate a suitable treatment plan.
In terms of chemical synthesis, 4-3-methoxyphenylglycolic acid also plays an indispensable role. Due to its special chemical properties, it can be used as a medium for the synthesis of many bioactive compounds. For example, some chemical molecules with specific physiological activities need to be synthesized with the help of vanilla mandelic acid, which can be reacted by a series of refined chemicals to generate the required chemical molecules, so as to provide the specific therapeutic effects of the chemical.
In addition, in some biological chemical studies, this compound can be used to investigate the cellular signaling pathway and substitution. Researchers have studied the degree of vanillic mandelic acid or its phase substitution, observed the transformation of cellular physiological functions, and gained in-depth insights into the biochemical process of biological and biological research. Therefore, 4-methoxyphenylglycolic acid plays an important role in many fields such as research, chemical synthesis and biological chemistry.
What are the physical properties of 4-fluoro-3-methoxyphenylacetic acid?
4-Hydroxy-3-methoxyphenylglycolic acid, its properties are white to light yellow crystalline powder, odorless, slightly bitter taste. Melting point is about 148-152 ° C, easily soluble in hot water and ethanol, slightly soluble in ether and chloroform.
This substance is relatively stable at room temperature, and is prone to decomposition and deterioration when exposed to light, heat or contact with strong oxidants. Its aqueous solution is acidic, with a pH value of about 3-5. It can be stored for a long time in a dry environment. If the ambient humidity is high, it may absorb moisture and agglomerate.
4-Hydroxy-3-methoxyphenylglycolic acid has unique solubility characteristics in organic solvents. In ethanol, hydrogen bonds can be formed between molecules, so it has good solubility; in non-polar solvents such as ether and chloroform, it can only be slightly soluble due to molecular polarity differences. Its melting point characteristics also reflect the state of intermolecular forces, and the specific melting point range indicates the regularity and stability of its molecular structure.
In chemical reactions, due to the activity of hydroxyl groups, methoxy groups and carboxyl groups, it can participate in esterification, etherification, neutralization and many other reactions, which are all based on its unique physical properties. Its acidity originates from the ionization of carboxyl groups, which can neutralize with bases in solution to generate corresponding salts. In the field of organic synthesis, these physical properties provide many possibilities for it to participate in the synthesis of various complex compounds as an important intermediate.
What are the chemical properties of 4-fluoro-3-methoxyphenylacetic acid?
4-Alene-3-methoxyphenylacetic acid is an organic compound containing alkenyl, methoxy and phenylacetic acid structural units. Its chemical properties are unique and have attracted much attention in the fields of organic synthesis and medicinal chemistry.
The alkenyl group is active in nature and has typical carbon-carbon double bond characteristics. Addition reactions can occur, such as electrophilic addition with halogens (bromine, chlorine), to generate halogenated hydrocarbons. The reaction conditions are mild and often carried out in organic solvents at room temperature or low temperature. Under the action of catalysts (such as palladium-carbon), hydrogenation reactions can occur with hydrogen to generate saturated hydrocarbons, which can realize the reduction of alkenyl groups. The alkenyl group can also participate in the oxidation reaction. Under the action of specific oxidants (such as ozone and potassium permanganate), the double bond breaks, and different oxidation products such as alcaldes, ketones or carboxylic acids are formed according to the reaction conditions and the type of oxidant. The
methoxy group acts as a power supply group, which has a significant impact on the electron cloud density of the benzene ring. It increases the electron cloud density of the ortho and para-position of the benzene ring, making the benzene ring more prone to electrophilic substitution. For example, under appropriate conditions, the phenyl ring of this compound can be alkylated with halogenated hydrocarbons catalyzed by Lewis acid (such as aluminum trichloride), and alkyl groups can be introduced into the benzene ring; it can also be acylated with acyl halides to introduce acyl groups,
Phenylacetic acid part, the carboxyl group is acidic, can neutralize with bases to form corresponding carboxylic salts, which have good solubility in water. Moreover, the carboxyl group can participate in the esterification reaction, react with alcohols under the catalysis of concentrated sulfuric acid to form ester compounds, which are often used in organic synthesis to prepare esters with specific functions and expand the application range of compounds.
4-ene-3-methoxyphenylacetic acid has become a key intermediate in the field of organic synthesis due to these chemical properties, which can be used to construct complex organic molecules; in pharmaceutical chemistry, it may exhibit unique biological activities due to these structures and properties, providing an important direction for drug development.
What are the synthesis methods of 4-fluoro-3-methoxyphenylacetic acid?
To prepare 4-ene-3-methoxyphenylacetic acid, you can do it from the following ways.
First, starting with benzene, alkylation through Fu-gram, introduction of alkyl groups, and then halogenation, hydrolysis and other steps to convert alkyl groups to carboxyl groups. At the same time, at a suitable stage, methoxy groups are introduced by nucleophilic substitution and other methods. After multi-step reactions, the required carbon frame and functional groups are gradually constructed.
Second, benzene derivatives with suitable substituents are used as starting materials. If the starting material contains methoxy groups, the fragment containing alkenyl groups can be introduced by means of Grignard reaction, etc., and then the alkenyl groups can be further converted. At the same time, try to introduce carboxyl groups at appropriate positions. For example, first react with halogenated alkenes to form carbon-carbon bonds, and then oxidize to obtain carboxyl groups.
Third, some natural products or compounds with similar skeletons can also be used as raw materials. Through the modification and transformation of its specific functional groups, the synthesis of the target product can be achieved. For example, those with benzene rings and alkenyl groups and other similar structures are selected, and 4-ene-3-methoxyphenylacetic acid is obtained through protection, de-protection, and precise operations such as carboxylation and methoxylation.
The key to synthesis lies in precisely controlling the reaction conditions, such as temperature, pH, catalyst selection, etc., to ensure the selectivity and yield of each step of the reaction. It is necessary to pay attention to the interaction between functional groups, protect and de-protect in time, so as to achieve the synthesis of 4-ene-3-methoxyphenylacetic acid efficiently and orderly.
What is the price range of 4-fluoro-3-methoxyphenylacetic acid in the market?
I have not heard of the price range of "4-Jiang-3-Methylhydroxyphenylacetic acid" on the market. The name of this compound, or a specific chemical substance, is not known to me as an ordinary commercial substance.
If you want to know the price range on the market, you should visit the chemical market and chemical reagent suppliers. Practitioners there often know the price of various chemical substances. Or you can search for its traces on the online chemical material trading platform and observe the prices marked by various companies to indicate its price range.
However, these substances may involve special controls, and their transactions may be subject to regulations and are not available at will. And when checking its price, the supplier's qualification and reputation must be carefully reviewed to avoid fraud. If you want to use it, you should also follow safety regulations and should not be careless.