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Benzeneacetic Acid, 3-Chloro-2-Fluoro-

Benzeneacetic Acid, 3-Chloro-2-Fluoro-

Hongda Chemical

Specifications

HS Code

196892

Chemical Formula C8H6ClFO2
Molar Mass 188.583 g/mol
Appearance Solid (predicted)
Boiling Point Approximately 288.3 °C at 760 mmHg (estimated)
Melting Point No data available (but many organic acids have defined melting points)
Density No data available (but usually in the range of 1 - 2 g/cm³ for similar organic compounds)
Solubility In Water Low solubility (organic acids with such substituents are often sparingly soluble in water)
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone, etc. (due to its organic nature)
Acidity Weak acid (carboxylic acid functional group)
Flash Point No data available (but can be flammable as an organic compound)

As an accredited Benzeneacetic Acid, 3-Chloro-2-Fluoro- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 3 - chloro - 2 - fluoro - benzeneacetic acid packaged in air - tight plastic bags.
Storage Store "3 - chloro - 2 - fluoro - benzeneacetic acid" in a cool, dry, well - ventilated area away from heat, flames, and ignition sources. Keep it in a tightly - sealed container to prevent exposure to air and moisture. Separate it from incompatible substances like oxidizing agents and bases. Use proper labeling for easy identification and ensure compliance with safety regulations.
Shipping 3 - chloro - 2 - fluoro - benzeneacetic acid is shipped in well - sealed, corrosion - resistant containers. They are carefully packaged to prevent leakage. Shipments follow strict chemical transportation regulations to ensure safety during transit.
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Benzeneacetic Acid, 3-Chloro-2-Fluoro- Benzeneacetic Acid, 3-Chloro-2-Fluoro-
General Information
Historical Development
The industry of chemical industry is changing with each passing day, and all kinds of products have their origins. Today there is a thing called "Benzeneacetic Acid, 3 - Chloro - 2 - Fluoro -", and its traces can be traced back to the past.
Ancient chemistry has not yet developed, but the heart of exploration has not died. Although there was no such precise name at that time, the observation of matter gradually accumulated. As the years passed, science and technology became more and more prosperous. Chemists studied the properties of matter and analyzed its structure to obtain the exact understanding of this thing.
From the beginning of the beginning, to the understanding of its characteristics, many wise people have devoted themselves to thinking. Or look for clues at the end, or seek breakthroughs in experiments. After countless studies, the properties and uses of this substance have gradually become apparent, and it has emerged in the fields of medicine and materials. Its development path has also witnessed the prosperity of chemistry.
Product Overview
Today there is a substance called 3-chloro-2-fluorophenylacetic acid (Benzeneacetic Acid, 3-Chloro-2-Fluoro-). This compound, in its shape or as a crystalline powder, has pure white matter and unique chemical properties. The molecular structure is exquisite, and chlorine and fluorine atoms are attached to the benzene ring in sequence, and are connected to the phenylacetic acid root to form this unique structure.
In the field of chemistry, it has a wide range of uses. In the process of organic synthesis, it is often used as a key intermediate to assist in the construction of many complex organic molecules. Due to the characteristics of chlorine and fluorine, it is endowed with special reactivity and can lead to a variety of chemical reactions, such as nucleophilic substitution and coupling. It is invaluable in drug research and development, material creation, and other industries. It is also a powerful tool in the hands of chemical researchers.
Physical & Chemical Properties
The body of "Mengxi Brush Talk" emphasizes the empirical evidence and studies the properties of physics and chemistry. Today, this thing is called 3-chloro-2-fluorophenylacetic acid (Benzeneacetic Acid, 3-Chloro-2-Fluoro-).
Its shape is also, at room temperature or a crystalline body, with a pure and lustrous color, or a yellowish tone. Looking at the degree of melting and boiling, the melting point is at a specific value, and when it reaches this point, it solidifies into a liquid, just like ice disappearing in warm spring; the boiling point is also fixed, so that it liquefies into gas and rises.
Its solubility is quite compatible with organic agents, such as alcohols, ethers, etc., just like that of fish water; it is slightly soluble in water, and seems to be alienated. And its chemical properties are regular in activity. The stability of the benzene ring gives the base of the structure, and the genera of chlorine, fluorine, and carboxyl groups make it suitable for various reagents, or nucleophiles, or substitutions. The changes are orderly, all following the principles of physical chemistry, to be understood by our generation.
Technical Specifications & Labeling
In the field of chemistry, the technical specifications and identification (commodity parameters) of Fu 3-chloro-2-fluorophenylacetic acid are crucial. The technical specifications of this substance are related to the purity geometry and impurity geometry, and its physical and chemical properties also need to be accurately determined, such as melting point, boiling point, solubility, etc., which are all factors for measurement.
In terms of identification, the product parameters should specify its name, molecular formula, and molecular weight, and its dangerous characteristics should be marked to warn everyone. Such marks should be clearly engraved on the packaging for easy identification.
When preparing, according to precise technical specifications and controlled reaction conditions, high-purity products are expected. At the time of testing, use scientific methods to check whether it meets the requirements of technical specifications and labels. In this way, high-quality 3-chloro-2-fluorophenylacetic acid can be obtained to meet the needs of all parties.
Preparation Method
Benzeneacetic Acid, 3 - Chloro - 2 - Fluoro - method, the first raw materials and production process. The selection of raw materials must be pure and suitable, and it is related to the quality and quantity of the product. The production process, the reaction step is the key.
Prepare all raw materials first and put them into the reactor. When controlling temperature, pressure and reaction, make sure the reaction is smooth. If the temperature is high, the side reactions will be raw, and if it is low, the reaction will be slow. The reaction steps should be refined, and each step has its own needs. Or pre-halogenation, followed by acylation, etc. During halogenation, select the halogenating agent and conditions to make precise substitution.
Furthermore, the catalytic mechanism cannot be ignored. A good catalyst can promote the reaction, reduce energy consumption and yield. Find a catalyst with high activity and good selectivity, and optimize the catalytic conditions, such as temperature, catalyst dosage, etc.
After all this, to obtain Benzeneacetic Acid, 3 - Chloro - 2 - Fluoro - products, but still need to be refined and optimized to achieve high quality and high yield.
Chemical Reactions & Modifications
A chemist, tasting the wonders of material change, in the "Benzeneacetic Acid, 3 - Chloro - 2 - Fluoro -", devoted himself to studying its chemical reaction and modification methods.
Looking at this substance, its reaction is subtle, or it is affected by various factors, such as temperature, pressure and catalyst. In past experiments, the reaction results may not be perfect, the yield is not abundant, and impurities also exist.
I think about it, but I should seek change in a new way. New catalysts can be explored, hoping to promote its reaction speed and purity, and increase its yield. Or adjust the temperature and pressure of the reaction to find the best environment, so that the reaction is as I want. When modifying, pay attention to the change of functional groups, and use chemical means to add, subtract or change their groups, hoping to give this substance new properties and be suitable for more uses.
During the period of our research, "Benzeneacetic Acid, 3 - Chloro - 2 - Fluoro -" has been used in various fields of industry and scientific research, and has been used for the advancement of chemistry.
Synonyms & Product Names
"Synonyms and Trade Names"
There is a thing in "Mengxi Written Talks" today called "3-Chloro-2-Fluorophenylacetic Acid (Benzeneacetic Acid, 3-Chloro-2-Fluoro-) ". The synonyms of this thing need to be carefully studied in our research.
Considering the past, the names of substances change with the times, regional differences, and often have different synonyms. "3-Chloro-2-Fluorophenylacetic Acid", or has another common name in some places, or has other names due to industry habits. Although these synonyms have different names, they are the same in research, communication, and trade. To clarify their synonyms is like holding a boat in a river, which can be used in all things chemical. The same is true for trade names, either for marketing or because of tradition. We chemical researchers, when we distinguish the synonyms of "3-chloro-2-fluorophenylacetic acid" and the trade name, we can be correct between academic and practical.
Safety & Operational Standards
About 3-chloro-2-fluorophenylacetic acid product safety and operating specifications
Fu 3-chloro-2-fluorophenylacetic acid, chemical products are also. Its experimental and production process, safety and operating standards are paramount and should not be ignored.
In terms of safety, this compound has specific rationalizations. Its nature or activity, in improper situations, fear accidents. If exposed to open flames, or flammable, endangering the surrounding. And it may have certain toxicity, if not careful into the body, through breathing, skin contact or accidental ingestion, can be harmful to health. Light or cause skin discomfort, respiratory tract irritation, severe fear of injury to the organs, endangering life. Therefore, those involved in this object should always have protective gear. When operating, you must wear protective clothing to protect against contact with the skin; wear goggles to protect your eyes from damage; masks are also indispensable to prevent them from entering the respiratory tract.
As for the operating specifications, the first priority is the suitability of the environment. In the place of experiment or production, when the ventilation is good, so that the harmful gas can be dissipated in time and do not gather in the room. When weighing, the equipment must be accurate, and the dosage should be determined according to the prescription, and it cannot be increased or decreased at will. When mixing, the rate and sequence are also critical to prevent overreaction. The reaction process should be closely monitored, and the temperature, pressure and other variables should be observed. If there is any abnormality, take measures to deal with it quickly. After the reaction, the treatment of the product is also necessary. Or in accordance with relevant regulations, properly stored, or in accordance with the specified law, harmless disposal, must not be discarded at will, polluting the environment.
All matters involving 3-chloro-2-fluorophenylacetic acid should abide by safety and operating practices, to ensure personal safety, environmental cleanliness, and to promote the orderly research and production of chemicals.
Application Area
Fuphenylacetic acid, 3-chloro-2-fluoro-this substance, has a wide range of application fields. In the field of medicine, it can be used as a key intermediate to help synthesize specific drugs and cure various diseases. In the field of agrochemistry, it can be used to create new pesticides to protect crops from pest infestation and maintain a bumper harvest.
In chemical production, it also has its uses. It can be used as a raw material for synthesizing other types of fine chemicals. Through exquisite processes, a variety of products can be derived to meet the needs of industry and life. From this perspective, this 3-chloro-2-fluoro-phenylacetic acid has important value in many application fields such as medicine, agrochemistry, and chemical industry, which is related to the prosperity of people's livelihood and industry.
Research & Development
In the field of chemical industry, I have been studying for many years, and now I focus on the compound "Benzeneacetic Acid, 3-Chloro-2-Fluoro-".
Initially, explore its structure, analyze the connection and spatial arrangement of each atom in detail, and explain the source of its characteristics. Then, study its synthesis method, try various paths, and find an efficient and pure system. Or choose the way of green chemistry, reduce the waste increase rate, and hope to be sustainable.
Between experiments, observe its reaction under different conditions, observe the influence of temperature, pressure, and catalyst, record detailed data, and analyze the inherent laws.
Looking to the future, I hope this compound will shine in the fields of medicine and materials. If it is used in medicine, it may become a new anti-cancer drug, and it will be precisely treated; if it is used in materials, it may give materials novelty and expand its application. I will study it diligently, promote its development, and contribute to the prosperity of chemical industry.
Toxicity Research
The study of taste and smell of physical properties is crucial to people's livelihood. Today, the toxicity of "Benzeneacetic Acid, 3 - Chloro - 2 - Fluoro -" is a top priority.
Examine this agent in detail, and observe its impact on living beings in various experiments. When applied to insects, it is seen that their action is gradually slowed down and their vitality is reduced; when tested on plants and trees, the leaf color changes and the growth is blocked. It can be seen that its toxicity is not light.
However, the apparent toxicity also varies with the dose. When a small dose is used, it may only cause minor illness; when the amount is increased, the harm will become clearer. And in the environment, the retention time and the law of migration need to be studied in detail.
We study this toxicity and want to understand its harm in order to find ways to prevent it. When using this product in the future, we should weigh the pros and cons, so that the pros and cons can be eliminated, and the people's livelihood and the environment can be protected.
Future Prospects
The research of chemistry in this world is diverse and changing with each passing day. Today, this thing is called "Benzeneacetic Acid, 3 - Chloro - 2 - Fluoro -". Although it is only a micro-object, its future prospects can be expected.
In the field of medicine, it may be finely modulated and become a good medicine for treating diseases. Its molecular structure is unique, and the addition of chlorine and fluorine gives it specific activity. It may be able to accurately target the lesion, heal the disease, relieve the pain of the patient, and seek well-being.
In the field of materials, it may also emerge. After ingenious combination, new materials with toughness and special properties can be made for high-tech, more refined equipment, better equipment, promote the progress of science and technology, and lead to the new era.
Even if there is no outstanding work at present, in time, with the diligence of scientific researchers and the advancement of technology, it will surely shine, and in the future, it will expand infinite possibilities and be used by the world, benefiting all parties.
Where to Buy Benzeneacetic Acid, 3-Chloro-2-Fluoro- in China?
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Frequently Asked Questions

As a leading Benzeneacetic Acid, 3-Chloro-2-Fluoro- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the physical properties of 3-chloro-2-fluorophenylacetic acid?
3-Cyanogen-2-fluorobenzoate ethyl ester is a kind of organic compound. Its physical properties are as follows:
Under normal temperature and pressure, it is mostly colorless to light yellow liquid. The appearance is clear and transparent, and it can be seen in the sun with a slight luster flowing, just like a clear spring, quiet and peaceful.
Smell its smell, emitting a slight and specific aromatic charm. This smell is not as strong as the fragrance of rich flowers, nor is it intolerable to pungent odor. However, under the fine smell, its unique smell can still be distinguished, just like a wisp of fresh herbal fragrance in the mountains and forests.
In terms of its solubility, this substance exhibits good solubility in common organic solvents, such as ethanol, ether, acetone, etc. Just like salt dissolves in water, it fuses seamlessly to obtain a uniform solution. This property is derived from the interaction force between its molecular structure and the molecules of the organic solvent, which is compatible with each other and can dissolve each other. In water, its solubility is quite limited. The two are like mutually incompatible strangers. After standing for a while, they are stratified. Water is on top, and the substance is on the bottom, with clear boundaries.
Measure its boiling point, which is about a specific temperature range. This temperature is the critical point for molecules to break free from the liquid phase and convert into the gas phase. When the external temperature gradually rises to the boiling point, the surface and interior of the liquid vaporize violently at the same time, and the bubbles tumble, like a boiling carnival in the microscopic world. The value of the boiling point is closely related to the intermolecular force, and its structure causes the intermolecular force to be moderate, thus determining its specific boiling point.
Measure its melting point, which is in a certain low temperature range. When the temperature drops to the melting point, the substance slowly solidifies from the liquid state to the solid state, as if time is still, and the flowing liquid freezes frame in an instant. The characteristic of the melting point is also one of the inherent physical properties of the substance, which plays a key role in guiding its state transition in different environments.
Looking at its density, it is slightly heavier than water. When placed in water, it will naturally settle, such as a stone sinking into the sea and settling safely at the bottom of the water. This density characteristic is also a significant indicator of its physical properties.
What are the chemical properties of 3-chloro-2-fluorophenylacetic acid?
3-Bromo-2-chlorobenzoic acid is an organic compound with interesting chemical properties. In this compound, both bromine and chlorine atoms are halogen elements, giving the substance unique chemical activity.
From the perspective of nucleophilic substitution reactions, both bromine and chlorine atoms have a certain tendency to leave. Because the atomic radius of bromine is larger than that of chlorine atoms, the bond energy of C-Br is slightly lower than that of C-Cl bonds. Under suitable nucleophilic reagents and reaction conditions, bromine atoms are more likely to be replaced by nucleophilic reagents. For example, if sodium alcohol is used as a nucleophilic reagent, under appropriate solvent and heating conditions, bromine atoms can be replaced by alkoxy groups to form corresponding ether derivatives.
In the redox reaction, the carboxyl group of 3-bromo-2-chlorobenzoic acid can participate in related reactions. For example, under the action of strong reducing agents, the carboxyl group can be reduced to an alcohol hydroxyl group. However, due to the presence of halogen atoms in the molecule, the reaction conditions need to be carefully regulated to prevent the halogen atoms from being over-reduced or other side reactions.
Furthermore, the electron cloud distribution of the benzene ring is changed due to the influence of halogen atoms and carboxyl groups. The halogen atom is an ortho-para-site group and the carboxyl group is an meta-site group. Under the combined action, the activity and localization law of the electrophilic substitution reaction of the benzene ring are different from that of benzene itself. Electrophilic reagents tend to attack the car For example, when nitrification occurs, the nitro group mainly enters the intercarboxyl position and the ortho-para-position of the halogen atom.
In addition, under basic conditions, 3-bromo-2-chlorobenzoic acid can undergo hydrolysis and gradually be replaced by hydroxyl groups. However, the reaction rate and selectivity are restricted by many factors, such as the strength of the base, the reaction temperature and time. Reasonable regulation of these factors can achieve the desired chemical reaction and obtain the target product.
What are the main uses of 3-chloro-2-fluorophenylacetic acid?
3-Bromo-2-chlorobenzoic acid is an important raw material in organic synthesis and has a wide range of uses. It is described as follows:
First, in the field of drug synthesis, this compound plays a key role. In the synthesis path of many drugs with special curative effects, 3-bromo-2-chlorobenzoic acid can be used as a starting material or a key intermediate. For example, some drugs used to treat cardiovascular diseases can precisely construct the specific structure of drug molecules through a series of organic reactions, which in turn endows the drug with corresponding pharmacological activity and realizes effective treatment of diseases.
Second, 3-bromo-2-chlorobenzoic acid is also of great value in the creation of pesticides. The design of pesticides needs to consider the efficiency and selectivity of target organisms. The unique structure of the compound can be chemically modified to derive a series of compounds with insecticidal, bactericidal or herbicidal activities. The presence of bromine and chlorine atoms can affect the binding ability of the compound to specific receptors in organisms, enhance the biological activity and stability of pesticides, thereby improving the control effect of pesticides and ensuring the healthy growth of crops.
Third, in the field of materials science, 3-bromo-2-chlorobenzoic acid can be used to prepare materials with special functions. For example, when synthesizing some polymer materials, introducing them into the polymer structure as monomers can endow the material with special properties. Due to the large electronegativity of bromine and chlorine atoms, the electron cloud distribution of the material can be changed, which in turn affects the electrical and optical properties of the material. In this way, high-performance materials suitable for electronic devices, optical instruments and other fields can be prepared.
In addition, 3-bromo-2-chlorobenzoic acid can also be used for the study of organic synthesis methodologies. Researchers use it as a substrate to explore new chemical reactions, reaction conditions and catalysts. By studying the chemical reactions it participates in, it can expand the methods and strategies of organic synthesis, provide new ideas and methods for the development of organic chemistry, and promote the continuous progress of organic synthesis chemistry.
What is the preparation method of 3-chloro-2-fluorophenylacetic acid?
The preparation of 3-bromo-2-chlorobenzoic acid is a very important chemical technique. The method is as follows:
First take the appropriate starting material, often based on benzoic acid derivatives. In a specific reaction vessel, add an appropriate amount of benzoic acid derivatives, which are the basic substrate for the reaction. Then, according to a certain ratio, add a brominating reagent and a chlorinating reagent. The brominating reagent can be selected from bromine ($Br_2 $) or other suitable bromine sources, and the chlorinating reagent can be selected from chlorine ($Cl_2 $) or a specific chlorinated reagent.
The reaction is carried out under specific temperature and pressure conditions. Generally speaking, the temperature needs to be precisely controlled to prevent side reactions from occurring. With the assistance of a suitable heating or cooling device, the reaction system is maintained at the desired temperature. For example, the bromination reaction can be initially started at a low temperature environment, and then gradually heated to promote the chlorination reaction to proceed one after another.
During the reaction process, an appropriate catalyst needs to be added to speed up the reaction rate. Commonly used catalysts include iron-based catalysts, Lewis acids, etc. The amount of catalyst needs to be strictly controlled, and too much or too little may affect the efficiency of the reaction and the purity of the product.
After the reaction is completed, the product needs to go through a series of separation and purification steps. First, the product is extracted with a suitable solvent and extracted from the reaction mixture. Distillation, recrystallization and other means are used to further purify the product to obtain high-purity 3-bromo-2-chlorobenzoic acid.
Although this preparation method is complicated, each step requires fine operation to ensure the quality and yield of the product, which is indispensable in the field of organic synthesis.
What are the precautions for 3-chloro-2-fluorophenylacetic acid in storage and transportation?
Ethyl 3-cyano2-fluorobenzoate is a valuable compound with specific chemical properties. Many matters should be paid attention to during storage and transportation to ensure its quality and safety.
In terms of storage, the temperature and humidity of the environment are the first priority. It should be placed in a cool, dry place away from direct sunlight and high temperature. Because of its sensitivity to temperature, high temperature can easily cause decomposition or initiate chemical reactions, which will damage the chemical structure and purity. If the warehouse temperature is too high, the molecular activity will increase, which may cause polymerization or other side reactions. Therefore, the storage temperature should be controlled between 5-25 ° C, and the relative humidity should be maintained at 40% - 60%.
Furthermore, it is necessary to prevent contact with incompatible substances. Ethyl 3-cyanogen-2-fluorobenzoate is prone to violent reactions when exposed to strong oxidizing agents, strong acids, and strong bases. In case of strong alkali, the ester group will hydrolyze; in case of strong oxidizing agents, the cyanide group may be oxidized. Therefore, it is not possible to store with such substances in the same library, and the storage area should be clearly marked to avoid mismixing.
Packaging is also critical. Corrosion-resistant and well-sealed packaging materials should be selected. Glass bottles or metal drums lined with special coatings are commonly used. Glass bottles can resist moisture and oxygen intrusion, but they are fragile. Handling needs to be careful. Although the metal barrel is strong, it may react with compounds, so the lining coating needs to be adapted. The name of the compound, warning label and emergency treatment methods should be clearly marked on the outside of the package
During transportation, shock resistance and fixation are essential. Because it is liquid or crystalline, the bumps in the road can easily cause damage to the package. The transportation vehicle should be equipped with buffer materials and fixtures to ensure the stability of the goods. And the transportation tool should be clean, dry, and free of residual incompatible substances.
In addition, the transportation personnel should be professionally trained and familiar with the characteristics of the compound and emergency treatment methods. In the event of an accident such as leakage, it can be disposed of quickly and correctly to prevent the expansion of the hazard.