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Benzeneacetic Acid, 2-Bromo-4-Fluoro-

Benzeneacetic Acid, 2-Bromo-4-Fluoro-

Hongda Chemical

Specifications

HS Code

835904

Chemical Formula C8H6BrFO2
Molar Mass 233.035 g/mol
Appearance Solid (usually)
Solubility In Water Low (organic acid with non - polar benzene ring)
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone
Pka Typical for aromatic carboxylic acids (around 4 - 5, estimate based on similar compounds)
Reactivity Reactive due to bromo and carboxyl groups; can undergo substitution, esterification reactions

As an accredited Benzeneacetic Acid, 2-Bromo-4-Fluoro- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 250g of 2 - bromo - 4 - fluoro - benzeneacetic acid in sealed chemical - grade packaging.
Storage 2 - bromo - 4 - fluorobenzeneacetic acid should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition sources. It should be kept in a tightly sealed container to prevent exposure to air and moisture. Store it separately from oxidizing agents, bases, and other incompatible substances to avoid potential chemical reactions.
Shipping Benzeneacetic Acid, 2 - bromo - 4 - fluoro - is shipped in accordance with strict chemical regulations. It's typically packed in well - sealed containers to prevent leakage, transported by specialized carriers handling hazardous chemicals.
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Benzeneacetic Acid, 2-Bromo-4-Fluoro- Benzeneacetic Acid, 2-Bromo-4-Fluoro-
General Information
Historical Development
The industry of chemical industry is changing with each passing day, and there are many substances. Today there is a substance called "Benzeneacetic Acid, 2 - Bromo - 4 - Fluoro -", which has also evolved in the field of chemical industry.
In the past, chemistry was first developed, and the exploration was not deep, and such compounds were little known. Later scholars studied, analyzed its structure, and explored its properties. Over the years, technology has become more and more advanced, and the synthesis method has become more and more exquisite. From the initial difficult exploration to the precise production, it all depends on the wisdom and diligence of craftsmen.
The development of this substance has witnessed the road of chemistry, from ignorance to clarity, from simplicity to complexity. The work of the predecessors is indelible, paving the way for later learning, so that this object can be gradually used in medicine, materials and other fields, shining brightly, and opening a new chapter.
Product Overview
Product Overview
Today there is a product called Benzeneacetic Acid, 2 - Bromo - 4 - Fluoro -. This is an organic compound, which is of great significance in the field of chemical research and industrial production.
Looking at its structure, on the benzene ring, bromine and fluorine atoms are ingeniously substituted, giving it unique chemical activity. The base of phenylacetic acid also adds color to its properties. Its physical properties, at room temperature, or in a solid state, with pure color and white matter, with specific melting points and boiling points, are related to separation and purification.
Discussing chemical properties, its reactivity is specific due to the conjugation effect of bromine, fluorine and benzene ring. It can participate in nucleophilic substitution, esterification and other reactions, and is a key intermediate in organic synthesis. It can derive a variety of organic compounds, playing an important role in the process of pharmaceutical and pesticide creation, assisting the development of new drugs, and contributing to human health and agricultural harvest.
Physical & Chemical Properties
Nowadays, there is a chemical substance called 2-bromo-4-fluorophenylacetic acid (Benzeneacetic Acid, 2-Bromo-4-Fluoro-), and its physical and chemical properties are particularly important. The form of this substance is either solid at room temperature, and its color is observed, or it is colorless to slightly yellow. Its melting point and boiling point are all characteristics. The melting point is related to the transformation of its physical state. At a specific temperature, it turns from solid to liquid. The boiling point is determined at what temperature it turns from liquid to gas.
Furthermore, the solubility cannot be ignored. In water and organic solvents, the state of dissolution varies. In organic solvents, it may have good solubility, which can help it disperse uniformly in chemical reactions to promote the progress of the reaction. Its chemical properties are active or not, depending on many reactions. The atoms of bromine and fluorine give it unique reactivity, which can react with a variety of reagents to form new compounds. It is quite useful in the field of organic synthesis.
Technical Specifications & Labeling
Today, there is a product called "Benzeneacetic Acid, 2 - Bromo - 4 - Fluoro-". In the field of chemical research in China, its technical specifications and identification (product parameters) are the key. The technical specifications of this product are related to the preparation method, from the selection of raw materials, accurate proportions, to the control of reaction conditions, temperature, pressure, and duration are all fixed, and a trace is not harsh, in order to obtain a pure and suitable product. The identification (product parameters) shows its physicochemical properties, such as melting point, boiling point, and purity geometry, which are the basis for users to implement policies. Examining its characteristics, detailing its norms, and correcting its logo are the constant tasks of our generation of chemical researchers. Only in this way can we make steady progress in the field of research and application, so that this product can be used effectively.
Preparation Method
In order to prepare 2-bromo-4-fluorophenylacetic acid (Benzeneacetic Acid, 2-Bromo-4-Fluoro-), the preparation method should be studied in detail.
First of all, when selecting pure starting materials to ensure the purity of the product. For example, select halogenated aromatics with specific purity and carboxyl-containing precursors, which are the reaction base.
As for the production process, the method of nucleophilic substitution can be followed. First, the halogenated aromatics and fluorine-containing reagents are reacted in a suitable solvent under the catalysis of a base at a temperature control, and fluorine atoms are introduced. After this step is completed, the bromine reaction is carried out, and the bromine atom is introduced at a specific position of the aromatic hydrocarbon under precise conditions. After the carboxylation reaction, it is skillfully converted to obtain the target product.
The reaction steps are crucial. Each step of the reaction needs to be strictly controlled by temperature and time, and attention should be paid to the ratio of materials. If the temperature is too high for nucleophilic substitution, the side reaction will be generated, and if it is too low, the reaction will be delayed.
The catalytic mechanism should not be ignored. Suitable catalysts can greatly improve the reaction rate and selectivity. Base acts as a catalyst to activate the reactants in the nucleophilic substitution to promote the efficient progress of the reaction. In this way, according to these methods, high purity 2-bromo-4-fluor
Chemical Reactions & Modifications
In the field of chemistry, the reaction and modification of Guanfu 2-bromo-4-fluorophenylacetic acid are of great importance to researchers.
The reaction of chemistry is the basis for material change. 2-bromo-4-fluorophenylacetic acid has a unique structure. The substitution of bromine and fluorine makes the distribution of benzene ring electron cloud different, causing its reactivity to change. Reactions such as nucleophilic substitution and electrophilic addition have different paths because of their functional groups.
As for modification, chemical means can be used to adjust its physical properties and chemical properties. Or increase its stability or change its solubility to suit various applications. For example, in the field of medicine, through subtle modification, it can become a more effective agent; in the field of materials, it can provide material-specific properties.
Chemical research explores the change of substances and seeks modification methods, hoping to be used by the world and benefit people's livelihood. This is the unremitting pursuit of our chemical researchers.
Synonyms & Product Names
The same name of 2-bromo-4-fluorophenylacetic acid and the trade name of
Fu 2-bromo-4-fluorophenylacetic acid are also chemical products. Its same name is the trade name, which is important in the world. This thing may have a general name, all of which are required for research purposes.
According to the reason of chemistry, its name is obtained according to. However, in the context of business and research, different families, different uses, or different names of their products.
If the same name is explored, it is based on the original product, and it is named by the method of. And the product name, mostly contains commercial considerations, or its characteristics, or it is easy to recommend.
Therefore, the same name and trade name of 2-bromo-4-fluorophenylacetic acid are mutually exclusive, and in the research and commercial activities of the chemical industry, each can do its own thing to promote the development of this chemical product.
Safety & Operational Standards
About 2-bromo-4-fluorophenylacetic acid product safety and operating specifications
Fu 2-bromo-4-fluorophenylacetic acid is an important product in chemical research. During its experiment and application, safety and operating standards are of paramount importance.
The first word is safe. This product has certain chemical activity, or has potential danger to the human body and the environment. When contacting, be extra cautious. If you accidentally touch the skin, rinse it with plenty of water as soon as possible, followed by a mild soap solution, check the skin for any discomfort, and seek medical treatment if there is any abnormality. If it enters the eye, it is necessary to immediately buffer with a large amount of water to make sure that the foreign body is exhausted, and then rush to the hospital. It is not a good thing to inhale the volatile gas of this product. If you feel poor breathing, dizziness, etc., leave the scene quickly and go to a well-ventilated place. If the symptoms are not solved, you should also seek medical attention.
Times and operating specifications. In the laboratory, appropriate protective equipment is necessary. The experimenter wears protective clothing, which is dense and can resist the penetration of chemicals; wears protective gloves, and chooses a material adapter to prevent the product from corroding or seeping into the skin through the gloves; and wears anti-goggles to protect the eyes from accidental splashes.
Furthermore, the operating environment should also be paid attention to. The operation should be done in the fume hood, so that the volatile gas can be discharged in time and avoid gathering in the room. When taking this product, the appliance must be clean and dry, and it must be taken according to the accurate measurement method to prevent errors from causing experimental deviations or safety accidents.
When storing, place it in a cool, dry and well-ventilated place, away from fire and heat sources. Separate from other chemicals to prevent mutual reaction.
In short, in the research and application of 2-bromo-4-fluorophenylacetic acid, strictly abide by safety and operating standards, so as to ensure the smooth experiment, personnel and environment are safe.
Application Area
Benzeneacetic Acid, 2 - Bromo - 4 - Fluoro - This substance has its uses in various fields. It is a genus of medicine and can be used as a medicine to treat diseases. Because of its chemical properties, it can be involved in biochemical reactions in the body and regulate physiological functions. In the fragrance industry, it can also be used as a raw material to give a unique aroma. Its structure and properties make the prepared fragrance have a unique smell and pleasing to the sense of smell. And in the field of material science, it may be able to participate in material synthesis, improve the properties of materials, increase their strength and toughness, etc. From this point of view, Benzeneacetic Acid, 2 - Bromo - 4 - Fluoro - has a wide range of applications, is related to people's livelihood and various industries, and has functions that cannot be underestimated in today's technology and life.
Research & Development
I have been in the field of chemistry for many years. Recently, the compound involved is 2-bromo-4-fluorophenylacetic acid (Benzeneacetic Acid, 2-Bromo-4-Fluoro-).
Study its quality, observe its properties, explore the method of synthesis, and seek the way of optimization. At first, try all kinds of paths, or the raw materials are difficult to find, or the yield is not good. However, unremitting research, repeated adjustment of the reaction conditions, temperature, pressure, and catalyst dosage are all carefully studied.
After repeated tests, the method is gradually obtained, and the yield is also considerable. And in this process, the deeper the understanding of its chemical properties. This compound has potential in the fields of medicine and materials. I hope that through continued research, it can be used more widely, and contribute to the academic and industrial circles, so as to fulfill my ambition in chemical research and development.
Toxicity Research
Since modern times, chemical refinement has brought about new innovations in various compounds. Today's research on this substance is called "Benzeneacetic Acid, 2 - Bromo - 4 - Fluoro -", and the study of its toxicity is quite important.
The toxicity of this compound is studied, and its structure is first observed. This compound has a unique structure. Bromine and fluorine atoms are attached to the framework of phenylacetic acid, or its properties are changed, and its toxicity is involved. Then look at its behavior in living organisms, or interact with cells, disturbing the biochemical process.
Taste it with all kinds of living beings. See its entry into the body, or hinder cell metabolism and damage the function of organs. The little ones cause discomfort, and the dramatic ones endanger life.
From this point of view, the toxicity of "Benzeneacetic Acid, 2 - Bromo - 4 - Fluoro -" cannot be underestimated. Researchers should be careful and investigate its properties in detail. It is not their responsibility to study it for the world to avoid harm and profit.
Future Prospects
I have tasted the industry of chemical industry, in Benzeneacetic Acid, 2 - Bromo - 4 - Fluoro - this thing, to observe its properties and investigate its use. Looking at the current state, although it has been achieved, it is still promising for future development.
This product is used in pharmaceutical chemical industry, or as an essential material, it can help the research of new drugs and solve the suffering of patients. Today's technology is changing with each passing day. If you improve the process with time, its production can be increased and quality can be improved. And the needs of the market also grow with the changes of the world. It is expected to expand its sales and widen its application.
Furthermore, the idea of environmental protection is gradually emerging, and the study of green production methods for this product is also the direction of the future. Hope to create beneficial things in a harmless way, which will not only benefit the industry, but also preserve the beauty of nature. In this way, the future of Benzeneacetic Acid, 2 - Bromo - 4 - Fluoro - will shine, be used by the world, and benefit people.
Where to Buy Benzeneacetic Acid, 2-Bromo-4-Fluoro- in China?
As a trusted Benzeneacetic Acid, 2-Bromo-4-Fluoro- manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading Benzeneacetic Acid, 2-Bromo-4-Fluoro- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the physical properties of 2-bromo-4-fluorophenylacetic acid?
The physical properties of 2-% hydroxy-4-enheptanedioic acid are as follows:
This substance is mostly white and crystalline at room temperature. When it is pure, the appearance is clean, and the crystals are regular and orderly. Smell it, few odors are emitted, and there is no special odor.
In terms of solubility, it has a certain solubility in water. Water is also the solvent of all things. 2-Hydroxy-4-enheptanedioic acid is soluble with water, but not infinitely miscible. This is because there are both hydrophilic hydroxyl groups and hydrophobic carbon chain parts in the molecular structure. In polar organic solvents, such as ethanol and acetone, its solubility is better. Ethanol, due to its polarity and hydrogen bonding, can interact with 2-hydroxy- 4-enheptanedioic acid to promote its dissolution.
The melting point has been determined by many experiments, and it is about a certain temperature range. When the temperature rises to the melting point, the substance gradually melts from a solid state to a liquid state. This process requires absorption of a certain amount of heat to overcome the lattice energy. The characteristics of its melting point are closely related to the intermolecular forces. Hydrogen bonds, van der Waals forces, etc. are intertwined to determine the melting point.
The density of the substance is also a specific value. For density, the mass per unit volume of the substance is also the same, and this value reflects the tightness of the arrangement of particles inside the substance. The density of 2-hydroxy-4-enheptanedioic acid makes it exhibit corresponding sedimentation or suspension characteristics when mixed with other substances in a specific environment.
As for the refractive index, it is also an important parameter to characterize its optical properties. When light passes through this substance, due to the influence of the internal structure of the substance on the speed of light propagation, the light is refracted, and the refractive index is a measure of its degree of refraction. This property is of great significance in optical analysis and identification.
What are the chemical properties of 2-bromo-4-fluorophenylacetic acid?
Ethyl 2-% 4-ethyl butyrate has the following properties:
This compound has the properties of an ester. Its molecule contains an ester group (-COO-), so it can be hydrolyzed. Under acidic conditions, 2-4-ethyl butyrate is hydrolyzed, and the ester group is cracked to produce 2-4-ethyl butyrate ethanol. Its inverse formula is generally: 2 - ethyl - 4 - ethyl butyrate + H _ 2O $\ xrightleftharpoons [H ^{+}]{}$ 2 - 4 - ethyl butyric acid + C _ 2O H _ OH. However, under the normal condition, the hydrolysis is more complete, and the ester group is reversed to generate 2 - 4 - ethyl butyrate ethanol, which is irreversible.
2 - 4 - ethyl butyrate (-OH) also makes it specific. In case of carboxylic acid or its derivatives, under the action of catalysis, the carboxylic group (-COOH) can be combined with water to form a new ester.
In addition, because it contains a multi-active group, it can be substituted and reversed. The atom of the alkyl group can be replaced by other atoms or groups, such as the atom of the alkyl group, etc., to derive a variety of compounds.
And because of the presence of carbon in the alkyl group, it has certain flammability. Under the appropriate conditions, it can generate oxygen, generate carbon dioxide, generate water, and release energy.
The chemical properties of 2-ethyl-4-ethyl butyrate make it useful in a wide range of fields, such as chemical synthesis, chemical synthesis, etc. It can be used for the synthesis of more complex compounds.
What are the main uses of 2-bromo-4-fluorophenylacetic acid?
2-% hydroxy- 4-allylbenzoic acid, which was mentioned in the ancient times of "Tiangong Kaiwu" or not explicitly mentioned, is widely used in today's chemical use.
In the field of organic synthesis, it is an important intermediate. It can be converted into many organic compounds with special functions through specific chemical reactions. For example, by esterification reaction, it can be combined with alcohols to form corresponding ester compounds. Such esters are often used as fragrance components in the fragrance industry to give fragrances a unique aroma and add their flavor level.
In the field of pharmaceutical chemistry, 2-hydroxy- 4-allylbenzoic acid also has potential value. Due to the activity check point of its molecular structure, it can be used as a lead compound for structural modification and optimization. By introducing different functional groups to change their physicochemical properties and biological activities, new drugs may be developed for the treatment of specific diseases.
In the field of materials science, this compound can also play a role. It can participate in polymerization reactions and become the structural unit of polymers. The formed polymer may have special physical properties, such as good thermal stability, mechanical properties, etc., and may provide unique performance advantages in the preparation of high-performance materials such as engineering plastics, composites, etc., to meet the diverse needs of different fields for material properties.
Although there is no direct record in "Tiangong Kaiwu", based on modern chemical knowledge, 2-hydroxy- 4-allylbenzoic acid has important uses in organic synthesis, medicine, materials and other fields, and plays an important role in promoting the development of various fields.
What are the synthesis methods of 2-bromo-4-fluorophenylacetic acid?
There are several methods for the synthesis of 2-hydroxy-4-methoxyphenylacetic acid. One method is to start with p-methoxybenzaldehyde, first with malonic acid in pyridine, with piperidine as the catalyst, Knoevenagel condensation reaction. This reaction also involves the action of the aldehyde group with the active methylene phase of malonic acid to decarboxylate to obtain trans-p-methoxycinnamic acid. After that, with an appropriate reducing agent, such as palladium carbon catalyzed by hydrogen reduction and double bond hydrogenation, 2-hydroxy-4-methoxyphenylacetic acid can be obtained.
Another method uses p-methoxyphenylacetonitrile as the starting material. First, it is hydrolyzed under alkaline conditions, and the nitrile group is converted to a carboxyl group to obtain p-methoxyphenylacetic acid. Then, in a suitable reaction system, the hydroxyl group is introduced into the ortho position. Halogenation can be used, such as halogenation with bromine under appropriate conditions, to obtain o-brominated p-methoxyphenylacetic acid, and then nucleophilic reagents, such as alcohol solution of sodium hydroxide, can be used through substitution reaction, and the hydroxyl group replaces the bromine atom, then the target product is obtained.
Another person uses p-methoxybenzene as a raw material. First, acetyl chloride is catalyzed by Lewis acid such as aluminum trichloride to perform a Fu-gram acylation reaction to obtain p-methoxyacetophenone. p-Methoxyacetophenone is obtained by α-halogenation reaction, such as N-bromosuccinimide (NBS) under the action of light or initiator. Then through hydrolysis, oxidation and other steps, the ketone group and halogen atoms can be converted to obtain 2-hydroxy-4-methoxyphenylacetic acid. Each method has its own advantages and disadvantages, depending on the ease of availability of raw materials, reaction conditions, and high or low yield.
What are the precautions for storing and transporting 2-bromo-4-fluorophenylacetic acid?
2-% heptyl-4-butyric acid is an organic compound. When storing and transporting, many matters must be paid attention to.
When storing, the first environment. It should be placed in a cool and ventilated warehouse, away from fire and heat sources. Because of its certain chemical activity, it is easy to cause danger when heated or exposed to open flames. The temperature of the warehouse should be controlled within a suitable range to prevent its properties from changing due to excessive temperature.
Furthermore, it should be stored separately from oxidants and bases, and mixed storage should not be avoided. The chemical properties of 2-% heptyl-4-allyl butyric acid make it meet with oxidizing agents, or cause severe oxidation reactions; when mixed with alkalis, it will also undergo chemical reactions, cause deterioration of substances, and/or be associated with danger.
Storage containers are also essential. A well-sealed container must be used to prevent it from evaporating and escaping into the environment, which will not only damage substances, but also endanger the safety of the environment and personnel. And the container material should be compatible with 2-% heptyl-4-allyl butyric acid and will not chemically react with it.
When transporting, ensure that the container does not leak, collapse, fall, or damage. The transportation vehicle should be equipped with the corresponding variety and quantity of fire fighting equipment and leakage emergency treatment equipment. Protect from sun exposure, rain and high temperature during transportation. If the package is damaged during transportation, 2-% heptanobutyric acid may leak, or cause harm to the transportation environment and surrounding personnel.
Transportation follows the specified route, do not stop in residential areas and densely populated areas. This is to avoid its leakage or accidents, causing serious harm to many people. Transport personnel should also be familiar with the characteristics of 2-% heptanobutyric acid and emergency treatment methods, so that in case of emergencies, they can respond quickly and correctly.