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Benzene, Bromopentafluoro- what is it used for?
Bromopentafluoro-benzene has a wide range of uses. In the field of chemical synthesis, it is often a key raw material. Its structure is unique, containing fluorine and bromine atoms, giving this compound specific properties.
In the organic synthesis path, bromine atoms can be used as activity check points for nucleophilic substitution reactions. When chemists want to introduce new functional groups, bromine atoms act like a wedge, providing an opportunity for new groups to settle in. The presence of fluorine atoms significantly enhances molecular stability and hydrophobicity.
In materials science, bromopentafluorobenzene can participate in the preparation of high-performance polymers. Due to its fluorine atom properties, the prepared polymer often has excellent thermal stability, chemical inertness and low dielectric constant, making it suitable for aerospace, electronic equipment and other fields that require strict material properties.
In the field of pharmaceutical chemistry, this compound is also involved. Its unique structure may become a key fragment for the optimization of lead compounds, helping to develop new drugs with high biological activity and good pharmacokinetic properties.
In industrial production, bromopentafluorobenzene is also an important intermediate for the preparation of specific fine chemicals. After a series of reaction transformations, it can produce a variety of high value-added products and occupy a place in modern industrial systems.
What are the physical properties of Benzene, Bromopentafluoro-
Bromopentafluoro-benzene is an organic compound. Its physical properties are quite unique, and today I will tell you in detail.
First of all, under room temperature, bromopentafluoro-benzene is a colorless to light yellow liquid, which is clear in appearance, like the condensation of jade dew. It has a special smell. Although it is not as fragrant as orchid musk deer, it has a unique smell of a chemical substance, and it can be felt unique when smelled.
As for the boiling point, the boiling point of this substance is about 127-128 ° C. When the temperature rises to this point, bromopentafluoro-benzene gradually converts from a liquid state to a gaseous state, such as the rise of clouds and fog, and realizes the phase change under specific conditions. The melting point of bromopentafluorobenzene is about -30 ° C. If the temperature drops, the liquid that originally flowed will solidify into a solid state, as if time is stagnant, showing a different form.
The density of bromopentafluorobenzene is about 1.925g/cm ³, which is heavier than water. If it is poured into water, it will sink slowly like a stone. And its solubility also has characteristics, slightly soluble in water, just like the difficulty of oil and water, but in organic solvents such as ethanol and ether, it has better solubility and can be fused with it, just like the combination of water and emulsion.
Furthermore, its vapor pressure is also one of the important physical properties. At a certain temperature, bromopentafluorobenzene will evaporate to produce steam, and the size of its vapor pressure depends on the difficulty of volatilization. This property is of great significance in many aspects such as chemical production and storage.
In summary, the physical properties of bromopentafluorobenzene have their own uses. In organic synthesis and other fields, because of their unique physical properties, they are either key raw materials or play a special role in the reaction process, adding a strong touch to the delicate picture of chemistry.
What are the chemical properties of Benzene, Bromopentafluoro-
Bromopentafluorobenzene has specific properties. This substance has the properties of halogenated aromatic hydrocarbons and is formed from benzene ring with bromine and pentafluoro atoms. It is chemically active. Due to the strong electronegativity of fluorine and bromine atoms, the electron cloud density of the benzene ring changes, and it has special manifestations in nucleophilic and electrophilic reactions.
When nucleophilic substitution occurs, the fluorine atom strongly absorbs electrons, so that the electron cloud density of the benzene ring decreases, which is conducive to the attack of nucleophilic reagents. Bromine atoms are more active and can be replaced by nucleophilic reagents, such as sodium alcohol, amines and other nucleophilic reagents. Bromine can be substituted with alkoxy groups, amino groups
In the electrophilic substitution, although fluorine and bromine are ortho-para-localized groups, due to strong electron absorption, the electron cloud density of the benzene ring decreases, and the electrophilic substitution activity is weaker than that of benzene. However, under suitable conditions and electrophilic reagents, such as halogenating agents, nitrifying agents, etc., new groups can still be introduced at specific positions in the benzene ring.
It has a certain stability, but under high temperature, strong base or strong oxidizing agent, the structure may change. When exposed to metal reagents, such as magnesium, lithium, etc., it can form organometallic compounds, which can be used as intermediates in organic synthesis to expand its reactivity and application. Bromopentafluorobenzene is rich in chemistry and has
What is the preparation method of Benzene, Bromopentafluoro-
To make bromopentafluorobenzene, first take pentafluorobenzene, place it in a reaction kettle, cool it in an ice-salt bath, and reduce the temperature in the kettle to about -10 ° C to 0 ° C. Then slowly add bromine dropwise. The speed of dropwise addition should be stable, and the reaction should not be overly dramatic. When adding dropwise, continue to stir to make the material mix evenly. The amount of bromine, depending on the amount of pentafluorobenzene in stoichiometric ratio, can be slightly excessive to promote the completion of the reaction.
After adding dropwise, remove the ice-salt bath, and gradually heat up to room temperature, so that the reaction can continue. During this process, it is necessary to pay attention to the phenomenon of the reaction, and observe whether it has color changes, gas escape, etc. At the time of reaction, an appropriate amount of catalyst, such as iron powder or iron tribromide, can be added to increase the rate of reaction.
When the reaction is completed, pour the reaction solution into the separation funnel and wash with an appropriate amount of water to remove unreacted bromine and water-soluble impurities. Then extract with an organic solvent, such as dichloromethane or ether, to collect the organic phase.
The organic phase is dried with anhydrous sodium sulfate to remove the moisture. After drying, the desiccant is filtered and removed. The filtrate is distilled under reduced pressure with a rotary evaporator. The organic solvent is first evaporated, and then the fraction of bromopentafluorobenzene is collected to obtain pure bromopentafluorobenzene. The whole process, the operation should be careful, pay attention to safety, and prevent
Benzene, Bromopentafluoro - What are the precautions in storage and transportation?
Bromopentafluorobenzene is also a chemical substance. When storing and transporting, many things need to be paid attention to.
First of all, store it, and it should be placed in a cool and ventilated warehouse. Because bromopentafluorobenzene is prone to danger when heated, under high temperatures, or its chemical properties change, causing disasters such as leakage. The temperature of the warehouse should be controlled within a reasonable range and should not be too high. And it should be kept away from fires and heat sources, both of which are prone to fire and combustion, endangering safety. Furthermore, it should be stored separately with oxidants and edible chemicals to prevent mutual reaction and harmful substances.
As for transportation, the transportation vehicle must be equipped with the corresponding variety and quantity of fire equipment and leakage emergency treatment equipment. If there is a leak on the way, it can be dealt with in time. The trough (tank) car used during transportation should have a grounding chain, and holes can be set in the trough to baffle to reduce shock and generate static electricity. If static electricity accumulates too much, it may cause fire and explosion. Make sure that the container does not leak, collapse, fall or damage during transportation. During transportation, it should be protected from sun exposure, rain and high temperature. It is advisable to transport in the morning and evening in summer to avoid high temperature periods. Load and unload lightly to prevent damage to packaging and containers. If the packaging is damaged, bromopentafluorobenzene will leak, which will pollute the environment and endanger the human body.