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What are the chemical properties of Benzene, 5- (4 '-Ethyl [1,1' -Bicyclohexyl] -4-Yl) -1,2,3-Trifluoro-
This is 5- (4 '-ethyl [1,1' -dicyclohexyl] -4 -yl) -1,2,3 -trifluorobenzene, which has unique chemical properties. From the structural point of view, the benzene ring is connected with a specific dicyclohexyl substituent, and contains fluorine atoms. Fluorine atoms have the characteristics of strong electronegativity, resulting in changes in the distribution of electron clouds of this compound.
Due to the high electronegativity of fluorine atoms and their strong ability to attract electrons, in the benzene ring system, the electron cloud density of the benzene ring will be affected, so that the activity of the electrophilic substitution reaction of the benzene ring is different from that of conventional benzene derivatives. Or reduce the electron cloud density of the benzene ring, making it more difficult for the electrophilic reagent to attack
The dicyclohexyl substituent has a large steric hindrance. This spatial effect may interfere with the interaction between molecules and affect its physical properties, such as melting point, boiling point, etc. And in chemical reactions, the steric hindrance may affect the reaction path and product selectivity. Some reactions that need to be close to specific atoms may be hindered by the steric hindrance.
Furthermore, the ethyl group of the longer carbon chain in the molecule increases the lipid solubility of the molecule. This may cause it to have different solubility in different solvents, better solubility in fat-soluble solvents, and poor solubility in water-soluble solvents. Such chemical properties make the compound have unique applications in materials science, medicinal chemistry and other fields. In the field of materials, it is possible to use its special electronic and spatial structure to prepare materials with specific properties; in medicinal chemistry, or due to its unique properties, it exhibits specific biological activities and becomes a potential lead compound for drug development.
What are the physical properties of Benzene, 5- (4 '-Ethyl [1,1' -Bicyclohexyl] -4-Yl) -1,2,3-Trifluoro-
This is a complex organic compound called 5- (4 '-ethyl [1,1' -dicyclohexyl] -4 -yl) -1,2,3 -trifluorobenzene. Its physical properties are quite characteristic, let me tell you one by one.
First of all, under normal temperature and pressure, it is mostly in the form of a colorless to light yellow liquid, which is clear and translucent. It looks like a clear spring, refracting a slight luster.
When it comes to the boiling point, this compound has a complex molecular structure, strong intermolecular forces, and a high boiling point. It needs a considerable amount of heat to boil into a gaseous state within a certain temperature range. The melting point of
cannot be ignored either. At a specific temperature, it will quietly change from solid to liquid. This melting point temperature is its inherent property and provides an important reference for research and application.
In terms of solubility, in organic solvents such as toluene and dichloromethane, it exhibits good solubility, just like a fish entering water and can be fused with it. In water, due to the hydrophobicity of its molecular structure, its solubility is extremely poor, almost insoluble in water, just like oil floating on the water surface, and it is distinct.
Density is also an important physical property. Compared with water, its density may be larger or smaller, depending on the relative mass of the molecules and the way they are deposited. This property needs to be taken into account during actual operation and storage.
Furthermore, its stability is also worthy of attention. Under general environmental conditions, the structure is relatively stable and is not prone to spontaneous decomposition or reaction. In case of extreme conditions such as specific chemical reagents, high temperature, and strong light, the chemical bonds in the molecule may be affected, triggering chemical reactions and changing its chemical structure and properties.
The physical properties of this compound have a profound impact on its application in organic synthesis, materials science, and other fields. Researchers need to design experiments and application plans according to its characteristics.
What are the application fields of Benzene, 5- (4 '-Ethyl [1,1' -Bicyclohexyl] -4-Yl) -1,2,3-Trifluoro-
5 - (4 '-ethyl [1,1' -dicyclohexyl] -4 -yl) -1,2,3 -trifluorobenzene, this compound is used in many fields due to its unique chemical structure.
In the field of materials science, it can be used as the cornerstone of high-performance materials. Due to its fluorine atom, it confers excellent thermal stability, chemical stability and low surface energy. These characteristics make it shine in the preparation of special coating materials, such as the preparation of non-stick pan coatings, which make food difficult to adhere due to low surface energy; used in building exterior wall coatings, with its chemical stability and thermal stability, resist wind and rain erosion and high temperature effects, and extend the service life of building exterior walls.
In the field of electronics, with its stability and unique electronic characteristics, it can be used to manufacture organic electronic devices, such as organic field effect transistors and organic Light Emitting Diodes. Due to its stable structure, it can ensure the stable operation of the device under long-term use and different environmental conditions, and improve the performance and reliability of electronic devices.
In the field of pharmaceutical chemistry, or with potential biological activity. The structure of fluorobenzene is often found in many drug molecules because it can modify the lipophilicity, metabolic stability and biological activity of compounds. By introducing this structural unit, new therapeutic drugs may be developed, such as targeted therapeutic drugs for specific diseases, using its specific interaction with biological targets to precisely treat diseases while reducing damage to normal cells.
In addition, in the field of organic synthetic chemistry, as a key intermediate, it can participate in the construction of many complex organic molecules. Its unique structure provides organic synthetic chemists with a variety of reaction check points. Through various chemical reactions, organic compounds with rich structures can be derived, which contributes to the creation of new compounds and the development of organic synthesis methodologies.
What is the synthesis method of Benzene, 5- (4 '-Ethyl [1,1' -Bicyclohexyl] -4-Yl) -1,2,3-Trifluoro-
To prepare this 5- (4 '-ethyl [1,1' -dicyclohexyl] -4 -yl) -1,2,3 -trifluorobenzene, the method is as follows:
First take an appropriate amount of 4- (4 -ethylcyclohexyl) cyclohexanone, place it in a clean reactor, add an appropriate amount of fluorination reagent, such as fluoride-containing halides, at a suitable temperature and pressure, the ketone group is fluorinated. After carefully monitoring the reaction process, when the reaction reaches the desired level, a fluorine-containing ketone intermediate is obtained.
Subsequently, the intermediate is reduced. Select a suitable reducing agent, such as metal hydride, and reduce the ketone group to the corresponding alcohol hydroxyl group under specific reaction conditions to obtain a fluorine-containing alcohol intermediate.
Then the fluorine-containing alcohol intermediate is condensed with benzene. Add a suitable catalyst to the reaction system, such as Lewis acid, to promote the condensation of the two at a specific temperature and time to generate the target product 5- (4 '-ethyl [1,1' -dicyclohexyl] -4 -yl) -1,2,3 -trifluorobenzene.
After the reaction is completed, the product is separated and purified. Methods such as column chromatography and recrystallization can be used to remove impurities and obtain pure target products. The whole process requires attention to the precise control of reaction conditions, the non-destructive transfer of materials between steps, and the cleanliness of the experimental environment, so that the product yield and purity can be excellent.
What is the environmental impact of Benzene, 5- (4 '-Ethyl [1,1' -Bicyclohexyl] -4-Yl) -1,2,3-Trifluoro?
The impact of 5- (4 '-ethyl [1,1' -dicyclohexyl] -4-yl) -1,2,3-trifluorobenzene on the environment is related to the role of chemical substances in the surrounding world.
View the structure of this substance, 5- (4 '-ethyl [1,1' -dicyclohexyl] -4-yl) partially contains a complex cyclic structure, with considerable spatial resistance and hydrophobicity. Hydrophobic or cause it to be insoluble in the aqueous phase, easy to accumulate in lipids or non-polar environments. If released into natural water bodies, or adsorbed on suspended particles and sediments, it will affect the habitat of aquatic organisms.
1,2,3-trifluorobenzene part, the fluorine atom has strong electronegativity, causing molecular polarity to change. The change of polarity may affect its interaction with other substances in the environment. And fluorinated organic compounds have high stability in the environment and are difficult to degrade. If this substance enters the soil, it may persist for a long time due to stability and hydrophobicity, changing the physical and chemical properties of the soil, hindering the absorption of nutrients and water by plant roots, and affecting the growth of vegetation.
In the atmospheric environment, this substance may evaporate to form volatile organic compounds (VOCs). Under light, VOCs can photochemically react with other pollutants in the atmosphere, such as nitrogen oxides, to generate secondary pollutants such as ozone, exacerbating air pollution and endangering human health and ecological balance.
And due to its complex structure and fluoride-containing properties, microorganisms have limited ability to degrade it. It is difficult to decompose rapidly in the natural environment through conventional biological processes, or continue to migrate and transform in environmental media, resulting in long-term potential harm.
In summary, the structural characteristics of 5- (4 '-ethyl [1,1' -dicyclohexyl] -4-yl) -1,2,3-trifluorobenzene may have many adverse effects on water, soil and atmospheric environments, and its production, use and discharge should be treated with caution to prevent irreparable damage to the ecological environment.