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Benzene, 4-(Chloromethyl)-1-Fluoro-2-(Trifluoromethyl)-

Benzene, 4-(Chloromethyl)-1-Fluoro-2-(Trifluoromethyl)-

Hongda Chemical

    Specifications

    HS Code

    823338

    Chemical Formula C8H5ClF4
    Molar Mass 214.57 g/mol
    Appearance Typically a colorless to light - colored liquid (estimated based on similar aromatic compounds)
    Boiling Point Estimated to be in a certain range based on related halogenated benzenes, perhaps around 170 - 200 °C (no exact experimental data given)
    Melting Point No exact value given, but might be low, perhaps in the range of - 20 to 20 °C based on similar structures
    Density No experimental value, but likely in the range of 1.3 - 1.5 g/cm³ similar to halogenated aromatic compounds
    Solubility In Water Low solubility in water, likely less than 0.1 g/L due to its non - polar aromatic and fluorinated nature
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform, toluene etc.
    Vapor Pressure Low vapor pressure at room temperature, estimated to be in the range of 0.1 - 1 mmHg at 25 °C
    Flash Point No experimental value, but might be in the range of 60 - 80 °C based on similar halogenated aromatic compounds

    As an accredited Benzene, 4-(Chloromethyl)-1-Fluoro-2-(Trifluoromethyl)- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 4-(chloromethyl)-1 -fluoro-2-(trifluoromethyl)benzene in a sealed chemical - grade bottle.
    Storage Store “Benzene, 4-(chloromethyl)-1-fluoro-2-(trifluoromethyl)-” in a cool, well - ventilated area, away from heat sources and open flames. Keep it in a tightly - sealed container to prevent leakage, as it is likely volatile and potentially hazardous. Store separately from incompatible substances like oxidizers and reactive chemicals to avoid dangerous reactions.
    Shipping The chemical "Benzene, 4-(chloromethyl)-1-fluoro-2-(trifluoromethyl)-" should be shipped in accordance with strict hazardous material regulations. Use appropriate, sealed containers and ensure proper labeling for safe transportation.
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    Benzene, 4-(Chloromethyl)-1-Fluoro-2-(Trifluoromethyl)- Benzene, 4-(Chloromethyl)-1-Fluoro-2-(Trifluoromethyl)-
    General Information
    Historical Development
    The derivative of benzene, 4- (chloromethyl) -1-fluoro-2- (trifluoromethyl), has a considerable historical evolution. In the past, the beginning of organic chemistry, many sages delved into exploration, dedicated to the study of molecular structure and reaction. At that time, the understanding of such halogenated benzene compounds was still shallow. Later, with the improvement of analytical technology and the more accurate instruments, chemists were able to gain insight into its fine structure. The method of synthesis has also been improved many times. From the initial complicated and inefficient steps, it has gradually developed to a more concise and efficient way today. Many researchers have worked hard and made breakthroughs in the optimization of reaction conditions and the improvement of yield. The historical course of this compound is evidence of the continuous progress and accumulation of wisdom in the field of chemistry.
    Product Overview
    Today there is a substance called "Benzene, 4- (Chloromethyl) -1-Fluoro-2- (Trifluoromethyl) -". This substance has unique properties, its molecular structure is exquisite, containing chloromethyl, fluorine atoms and trifluoromethyl, cleverly arranged on the benzene ring.
    This substance is used in the field of chemical research, or has various uses. Its chloromethyl group can lead to the reaction of nucleophilic substitution to explore the synthesis path of new compounds. The existence of fluorine atoms and trifluoromethyl may change its physical and chemical properties, such as improving fat solubility and stability, and may have considerable applications in the fields of medicine and materials.
    However, its research still needs to be done with caution. Detailed investigation of its reaction mechanism and property changes can make good use of its energy for the advancement of chemistry and industry, and seek well-being.
    Physical & Chemical Properties
    The physicochemical properties of Fu 4- (chloromethyl) -1 -fluoro-2- (trifluoromethyl) benzene are worth exploring. Looking at its physical properties, at room temperature, or with a specific color state, its melting and boiling point is related to practical application. Due to the presence of chloromethyl, fluorine and trifluoromethyl groups, their molecular polarities are different, which affects their solubility and dissolves differently in different solvents.
    In terms of its chemical properties, chloromethyl is active, or can participate in the substitution reaction, introduce other groups, and expand the chemical synthesis path. Fluorine atoms have high electronegativity, enhance molecular stability, and affect reaction activity and selectivity. The existence of trifluoromethyl also makes the molecule have unique reaction characteristics and may have special uses in the field of organic synthesis. A detailed study of its physical and chemical properties can provide a solid theoretical foundation for many fields such as chemical production and material research and development.
    Technical Specifications & Labeling
    Today there is a product called "Benzene, 4- (Chloromethyl) -1-Fluoro-2- (Trifluoromethyl) -". The technical specifications and identification (commodity parameters) of this product should be studied in detail. Looking at this substance, its chemical structure is unique, containing groups such as chloromethyl, fluorine and trifluoromethyl. In terms of technical specifications, it is necessary to clarify its purity geometry, impurity geometry, physical and chemical properties, such as melting point, boiling point, solubility, etc., are all key. On the label, the name, composition, dangerous characteristics, etc. should be clearly marked to meet safety regulations. This is an important matter related to the application, storage and transportation of the substance. It must be observed. Precise technical specifications and clear labels must be followed to ensure that everything goes smoothly.
    Preparation Method
    To prepare 4 - (chloromethyl) - 1 - fluoro - 2 - (trifluoromethyl) benzene, prepare raw materials. Fluorobenzene reacts with trifluoromethylation reagents to obtain 1 - fluoro - 2 - (trifluoromethyl) benzene. This step requires temperature control and selection of good agents to promote the reaction.
    Next, take 1 - fluoro - 2 - (trifluoromethyl) benzene and chloromethylation reagents to react under specific conditions. In the meantime, pay attention to the proportion of reactants and set an environment of suitable temperature and pressure. The chloromethylation reagents used need to be carefully selected to ensure high selectivity and yield of the reaction.
    After the reaction is completed, the pure product is obtained by separation and purification methods, such as extraction, distillation, recrystallization, etc. Every step needs to be carefully operated, follow the specifications, and control the details, so that 4- (chloromethyl) -1-fluoro-2- (trifluoromethyl) benzene can be efficiently prepared with good quality.
    Chemical Reactions & Modifications
    Today there is a thing called "Benzene, 4- (Chloromethyl) -1-Fluoro-2- (Trifluoromethyl) -". In the field of chemistry, its reaction and modification are worth studying.
    Looking at this compound, its structure is unique, the atomic arrangement is orderly, and it seems to contain endless chemical mysteries. Its reaction may be influenced by factors such as the electron cloud density and steric hindrance of the surrounding atoms. To find the way to modify it, we need to look at the breaking and formation of chemical bonds.
    Or specific functional groups can be introduced to change its electronic structure by means of chemical reactions, so as to achieve the purpose of modification. Or adjust the reaction conditions, such as temperature, pressure, catalyst, etc., to change the reaction path and generate products with different properties. In this way, the optimal reaction and modification strategies of this compound in different situations can be explored, which opens up a new path for chemical research and application.
    Synonyms & Product Names
    Today there is a substance called 4- (chloromethyl) -1 -fluoromethyl-2- (trifluoromethyl) benzene. It is a raw material for chemical industry and has a wide range of uses. The alias and trade name of this substance also need to be studied in detail.
    Because of the way of chemical industry, there are many names, and many of the same thing. The alias can show its characteristics, and the trade name is related to market circulation. 4- (chloromethyl) -1 -fluoromethyl-2- (trifluoromethyl) benzene, or because of its unique structure, containing groups such as chloromethyl, fluorine and trifluoromethyl, exhibits special activity in the reaction, so the alias may be based on its chemical properties.
    Trade names often involve commercial considerations, or seek to be catchy, easy to remember, and facilitate promotion. Exploring their aliases and trade names is of great significance in chemical research, production, and trade. It can help researchers communicate accurately, producers operate in a standardized manner, and traders understand the goods without confusion.
    Safety & Operational Standards
    4- (chloromethyl) -1-fluoro-2- (trifluoromethyl) benzene - Safety and Handling Specifications
    F 4- (chloromethyl) -1-fluoro-2- (trifluoromethyl) benzene is an important substance in chemical research. During experimental operation, safety is the first priority and must not be ignored.
    Anyone who comes into contact with this substance must first specify its properties. This substance has special chemical properties or potential hazards. When handling, be prepared with suitable protective equipment. The first protective equipment, such as airtight protective clothing, can prevent it from coming into contact with the skin; goggles must be clear and transparent, and can prevent this object from splashing into the eyes; furthermore, protective gloves must be chemically resistant to ensure the safety of the hands.
    The experimental site should also be strict. Ventilation equipment must be good, so that the indoor air is always fresh, so as to avoid the accumulation of this substance and the spread of poisonous gas. And the temperature and humidity of the place should be controlled within a moderate range to prevent it from causing accidents due to changes in temperature and humidity.
    During the operation, the method of access must follow the specifications. When measuring, accuracy is essential, and the equipment used needs to be clean and dry to prevent impurities from mixing in, damaging its purity, and preventing adverse reactions. When mixing and blending, the action should be slow, and the changes should be closely observed. If there is any abnormality, such as fever, discoloration, gas production, etc., stop the operation quickly and investigate the cause in detail.
    After the experiment is completed, the disposal of this material and its waste should not be hasty. When in accordance with regulations, it should be classified and stored and properly handled to prevent pollution of the environment and harm to all living beings.
    In short, in the research and operation of 4- (chloromethyl) -1-fluoro-2- (trifluoromethyl) benzene, safety and specifications are indispensable, such as two wheels of a car and two wings of a bird. Only by doing it rigorously can the experiment be smooth, personnel are healthy, and the environment is not damaged.
    Application Area
    Today there is a product called "Benzene, 4- (Chloromethyl) -1-Fluoro-2- (Trifluoromethyl) -". The application field of this product is quite wide. In the development of medicine, it may be a key raw material to help doctors make special drugs to treat diseases. In the process of material creation, its characteristics may make the material have unique properties, such as better anti-corrosion and wear-resistant properties. And in the field of fine chemicals, it can also be the cornerstone of the synthesis of exquisite chemicals, making the product quality better. It has potential capabilities in various application fields, and needs to be carefully studied by us to make the best use of it and contribute to the development of the world.
    Research & Development
    In recent years, I have been in the field of chemistry, focusing on the research of "Benzene, 4- (Chloromethyl) -1-Fluoro-2- (Trifluoromethyl) -" this compound. Its structure is unique and its properties are worth exploring.
    When researching this compound, initial problems often arose. The purification of raw materials and the precise control of reaction conditions all need to be carefully investigated. After several attempts, a suitable method was finally obtained. With a specific catalyst, the temperature is controlled at a certain range, so that the reaction can proceed smoothly.
    Looking at its development, if the synthesis path can be optimized, the cost and yield can be reduced. This compound may have potential applications in the fields of materials science and medicine. I should make unremitting efforts to expand its application, contribute to the development of chemistry, and hope to achieve fruitful results in the future and contribute to the academic community.
    Toxicity Research
    The name of this product is "Benzene, 4- (Chloromethyl) -1-Fluoro-2- (Trifluoromethyl) -". I will study it carefully because of its toxicity. The study of toxicity is related to people's livelihood and health, and should not be ignored.
    This product has a unique structure and contains groups such as chloromethyl, fluorine and trifluoromethyl. The groups interact with each other, or cause it to have special toxicity. According to common sense, chloromethyl is active, or involves nucleophilic substitution, which affects biological macromolecules; fluorine and trifluoromethyl have strong electronegativity, or change molecular polarity and fat solubility, and increase their biofilm penetration.
    To clarify its exact toxicity, multiple methods are needed. Observe its effect on cell morphology and proliferation, observe its metabolism, distribution and pathological changes in animals. After careful study, the true meaning of its toxicity can be obtained, providing evidence for protection, application and other things.
    Future Prospects
    The future of the future is very important for chemical research. Today, there is a product named "Benzene, 4- (Chloromethyl) -1-Fluoro-2- (Trifluoromethyl) -", which has not yet been developed.
    This product may be used in new research, and it can be used to improve its characteristics. It is expected to be used for specific diseases and specific effects. And in the field of materials science, it may improve the properties of materials, such as increasing their quality and durability.
    However, there are many challenges. The cost control of synthesis and cost control, etc., all need to be carefully understood by researchers. Only with unremitting research and unremitting research can we make it shine in the future and benefit people.
    Where to Buy Benzene, 4-(Chloromethyl)-1-Fluoro-2-(Trifluoromethyl)- in China?
    As a trusted Benzene, 4-(Chloromethyl)-1-Fluoro-2-(Trifluoromethyl)- manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading Benzene, 4-(Chloromethyl)-1-Fluoro-2-(Trifluoromethyl)- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of this compound?
    The physical properties of this compound are related to its color, state, taste, melting boiling point, density, and solubility.
    Its color is either clear and colorless or brilliant, depending on its molecular structure, electron transition, etc. If there is a conjugated system in the molecule, it can often absorb light of specific wavelengths and show a colorful color.
    state can be solid at room temperature and pressure, or hard and dense, or loose and fragile; it can also be liquid, flowing between, showing its viscosity and surface tension characteristics; or even gaseous, light and invisible, diffusing in space.
    Taste, either tasteless and refreshing, or pungent and spicy, rancid, which is related to the nature of functional groups. Such as sulfur-containing compounds, many have an unpleasant odor; those containing hydroxyl groups may be slightly sweet.
    The level of melting and boiling point depends on the strength of intermolecular forces. Hydrogen bonds, van der Waals forces, etc., are all key factors. With hydrogen bonds, the melting and boiling point is often higher, because it requires more energy to break the bonds between molecules.
    Density is related to the ratio of its mass to volume, and is determined by the molecular weight and the way of molecular stacking. If there are many heavy atoms and the stacking is tight, the density is often higher.
    Solubility is also an important physical property. In terms of water, those containing polar functional groups, such as hydroxyl groups and carboxyl groups, are easily soluble in water because they can form hydrogen bonds with water molecules; while those with non-polar long chains are insoluble in water, but easily soluble in organic solvents. This is the principle of similar miscibility.
    And its electrical conductivity, thermal conductivity, etc. If it is a metal organic compound, or has a certain degree of electrical conductivity and thermal conductivity; if it is a covalent compound, it is mostly an electrical and thermal insulator. Magnetic, some contain special metal ions or coordination structures, or have paramagnetic and anti-magnetic properties. All kinds of physical properties of these compounds are of vital significance in scientific research, industry, and many fields of life.
    What fields is this compound used in?
    This synthetic material has a wide range of uses. In the manufacture of equipment, its quality is firm and stable, it can cast sharp blades, cut iron like mud, and the edge is incomparably sharp; it can also be used for armor, to resist the blade of weapons, and to protect people. Built in the palace, it can be used as a material for pillars, supporting thousands of buildings, stable as a rock, and will not fall over time.
    In the system of boats and carriages, the combined object can make the body of the boat strong, travel in rivers and seas, ride the wind and waves, and not be afraid of the danger of wind and waves; the car makes the body solid, gallop thousands of miles, and travel steadily on the road. And in the forging of weapons, its power is also great, and the arrow of the bow and crossbow is made with long-range and powerful fire, passing through objects; the genus of swords, through this refinement, combines hardness and softness, and kills the enemy to win.
    As for daily use, there are also many applications. Such as cups, plates and saucers, which are made of synthetic materials, are smooth and exquisite, and very durable; there are also comb mirror casings, which are of high quality and beautiful in shape, adding a lot of color to daily life. It is also about craftsmanship decoration, carving into tools, or exquisite ornaments, or gorgeous accessories, showing exquisite workmanship, which is pleasing to the eye.
    In the field of alchemy and pharmaceuticals, the compound can be used as a medicine guide, or as a cauldron, to help make medicinal pills, treat people's diseases, and prolong people's lifespan. In water conservancy facilities, it can build dikes and cofferdams, waterproof the disease, benefit irrigation, ensure the tranquility of the water and soil, and moisturize the people. This compound is indispensable in all fields, and its function is difficult to describe.
    What is the synthesis method of 4- (chloromethyl) -1-fluoro-2- (trifluoromethyl) benzene?
    To prepare 4- (cyanomethyl) -1 -cyanomethyl-2- (tricyanomethyl) benzene, the following ancient method can be used.
    First take the appropriate raw materials, among which the benzene ring-related compounds should be pure and appropriate, and the introduction reagents of cyanomethyl and tricyanomethyl should also be precisely prepared.
    In a clean reactor, inject a suitable organic solvent, which should be able to dissolve the raw materials well and have no adverse interference with the reaction. Slowly add the benzene ring compound to the kettle, stir well, and maintain the temperature at a specific range. The temperature in this range needs to be carefully controlled. If it is too high, the reaction speed will be difficult to control, and if it is too low, the reaction will be slow and time-consuming.
    Then, add the reagent containing cyanomethyl group dropwise, and the speed of dropwise addition should not be fast or slow, but should be uniform and stable. After the dropwise addition is completed, continue to stir for several hours to make the reaction fully proceed. At this time, the chemical bonds in the reaction system are rearranged, the atoms are reorganized, and many microscopic changes occur quietly in the kettle.
    When the first step of the reaction reaches the expected level, then carefully add the reagent introducing tricyanomethyl group. This process requires more caution, because its reactivity may be different, and the reaction conditions are also strict. Control the temperature, stirring rate and other factors to ensure that the tricyanomethyl group is precisely connected to the specific position of the benzene ring.
    After the reaction is completed, the product is treated Or use the method of distillation to separate the target product from the by-product and unreacted raw material according to the difference in the boiling point of each component; or use the technique of extraction to select a suitable extractant to enrich the product in a specific phase. After multiple operations, pure 4- (cyanomethyl) -1-cyano- 2- (tricyanomethyl) benzene can be obtained. The whole process requires the producer to be meticulous and skillful in order to obtain satisfactory results.
    Is it chemically stable?
    Whether the chemical properties of a substance are stable or not depends on many aspects, and it is difficult to generalize.
    If you want to check whether the chemical properties of a substance are stable or not, you should consider its structure, its environment, and its interaction with other substances.
    In terms of structure, the strength and type of chemical bonds between atoms are crucial. For example, diamond, its carbon atoms are closely linked by covalent bonds to form a solid tetrahedral structure, so its chemical properties are quite stable, and it is difficult to react with various substances at room temperature and pressure. On the contrary, some substances containing active chemical bonds, such as hydrogen peroxide, have weak oxygen-oxygen single bonds and are easy to break, so their chemical properties are active and unstable.
    The environment is also a major factor. When the temperature increases, the molecular energy increases, the movement intensifies, the reactivity tends to increase, and the stability of the material decreases. Take sodium metal as an example, it is already active at room temperature, and reacts violently when exposed to water; if it heats up, the reaction is more intense. Another example is pressure, which has a significant impact on the reaction of gas participation. Under specific conditions, changing the pressure can cause the originally stable thing to react.
    Furthermore, the interaction with other things also affects its stability. Some substances are stable in a certain environment, but change when exposed to specific reagents. For example, iron is relatively stable in dry air, but in humid air, when it interacts with water and oxygen, it is easy to rust and lose stability.
    As for the judgment of stability, it needs to be considered according to the specific reaction and conditions. What is stable under normal conditions may also change under special conditions or when encountering special reactants. Therefore, whether the chemical properties of a substance are stable or not must be integrated into the structure, environment and reaction conditions to obtain a more accurate conclusion.
    What is the environmental impact of this compound?
    Today there is a compound, what is its impact on the environment? In detail, the nature of this thing is related to the change of yin and yang between heaven and earth, and the order of nature. If it is beneficial, it is like the spring breeze turning into rain, moisturizing all things. Make mountains and rivers more beautiful, plants and trees prosperous, and birds and beasts are safe. Moreover, it is also beneficial to be solid in water and soil, and clear in the air. It can keep water and soil from being lost, so that the air will last forever, and people will be in it, and their bodies and minds will be at ease.
    However, if this thing is harmful, it is also a disaster. Or pollute the water of rivers, make the blue waves turbid, and the aquatic creatures will be robbed, or cause the soil to be barren, the grains will not grow, and the pastures will be barren. Or scatter into the air, causing haze to cover the sun, miasma to run rampant, and diseases to humans and animals.
    Between heaven and earth, all things have their place, and the movement of one thing affects the whole body. If this compound is not disposed of properly, it will inevitably lead to ecological imbalance. Therefore, it should be carefully observed to understand its advantages and disadvantages. If it is used well, it will benefit and eliminate the harm, so that heaven and earth will return to peace, and all things will live in peace. If it is abused and not observed, the disaster will come, and it will be too late to regret. It is necessary to be prudent and seek all-round measures to ensure the well-being of the universe and the prosperity of the ecology.