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Benzene, 4-(Bromomethyl)-2-Fluoro-1-Nitro-

Benzene, 4-(Bromomethyl)-2-Fluoro-1-Nitro-

Hongda Chemical

    Specifications

    HS Code

    214917

    Chemical Formula C7H5BrFNO2
    Molar Mass 236.02 g/mol
    Appearance Solid (likely, based on similar compounds)
    Solubility In Water Low, as it is an aromatic organic compound with non - polar benzene ring and hydrophobic groups
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform, due to its organic nature
    Vapor Pressure Low at room temperature due to its solid or high - boiling nature

    As an accredited Benzene, 4-(Bromomethyl)-2-Fluoro-1-Nitro- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100 - gram vial of 4-(bromomethyl)-2 - fluoro - 1 - nitro - benzene, well - sealed.
    Storage Store "Benzene, 4-(bromomethyl)-2-fluoro-1-nitro-" in a cool, dry, well - ventilated area away from heat, ignition sources, and incompatible substances. Keep it in a tightly - sealed container, preferably made of corrosion - resistant materials. Due to its potential hazards, it should be stored separately from oxidizing agents, reducing agents, and combustibles.
    Shipping The chemical "Benzene, 4-(bromomethyl)-2-fluoro-1-nitro-" must be shipped in accordance with strict hazardous materials regulations. It should be properly packaged in sealed, compatible containers to prevent leakage during transit.
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    Benzene, 4-(Bromomethyl)-2-Fluoro-1-Nitro- Benzene, 4-(Bromomethyl)-2-Fluoro-1-Nitro-
    General Information
    Historical Development
    Those who have studied chemistry in ancient times have been diligent in studying the changes of matter. Today, this thing is called "Benzene, 4- (Bromomethyl) -2-Fluoro-1-Nitro-". Its initial appearance was observed by scholars, but they did not know its nature. After years, everyone studied it carefully, and gradually understood its structure and characteristics.
    At the beginning, the exploration was difficult, the experiment was difficult, and the scholars were unremitting. Or one day, I occasionally got clues, and after repeated verification, I finally knew the mystery of its composition. From unknown to familiar, its journey is tortuous.
    Scholars after this, based on this, expand their applications. Or used in medicine, or used in materials. Looking at its historical development, it is like a river converging, starting from the beginning, and today, it has occupied a place in the field of chemistry, adding to scientific research and practicality, and witnessing the diligence and wisdom of scholars.
    Product Overview
    About 4- (bromomethyl) -2 -fluoro-1 -nitrobenzene
    Now there is a thing called 4- (bromomethyl) -2 -fluoro-1 -nitrobenzene. Its shape is also in the form of crystal powder, and the color is light or absent. Under light, it also has different colors. Looking at its structure, on the benzene ring, bromomethyl, fluorine, and nitro are in their respective positions, complementing each other, forming this unique shape.
    The properties of this thing are related to chemical changes. Because it contains nitro groups, it has the ability to oxidize; the existence of bromomethyl makes it active in the reaction of nucleophilic substitution. The fluorine atom adds its characteristics to many reactions, affecting the path and speed of the reaction.
    In the process of synthesis, the appropriate material is often selected by a specific method, and the material is obtained through multiple steps. In the field of chemical industry, it can be used as a raw material, laying the foundation for the synthesis of other kinds of fine things, and it also plays an important role in the creation of medicine and pesticides, or as a key intermediate, assisting the birth of new drugs and pesticides.
    Physical & Chemical Properties
    The physical and chemical properties of Fu 4- (bromomethyl) -2 -fluoro-1 -nitrobenzene are particularly important. Looking at its physical properties, at room temperature, what is the shape? What is the color like? Or solid, or liquid? What is the geometry of its melting point and boiling point? Regarding its solubility, in water and various organic solvents, it is soluble or insoluble, and what is the solubility?
    On its chemical properties, because it contains bromomethyl, fluorine, and nitro functional groups, it is very active. Nitro is highly oxidizing, bromomethyl can undergo nucleophilic substitution, and fluorine atoms also affect the reactivity of molecules because of their electronegativity. In the field of organic synthesis, or as a key intermediate, this substance participates in various reactions, forms new compounds, and is widely used in medicine, materials and other industries. A detailed study of the physical and chemical properties of this substance can open up a broad path for its application.
    Technical Specifications & Labeling
    Today there is a product called 4- (bromomethyl) - 2 -fluoro-1 -nitrobenzene. To clarify its technical specifications and labels (product parameters), it is necessary to carefully investigate.
    In technical specifications, the synthesis method needs to be rigorous. The material ratio must be accurate, and the reaction conditions must be strictly controlled. The temperature and duration are all related to the quality of the product. The reaction environment should be pure and should not be disturbed by impurities.
    When it comes to the label (product parameters), its physical properties need to be carefully remembered. Color, taste and state are all key points, and the melting point and solubility should not be ignored. The chemical properties should also be clear, the activity geometry, and the law of reaction with other substances. With accurate identification, this product can be fully displayed in front of the user, without error, so that it can be used to the fullest extent.
    Preparation Method
    To prepare 4 - (bromomethyl) - 2 - fluoro - 1 - nitrobenzene, first take fluorobenzene as the raw material, use nitrate-sulfur mixed acid, and control the temperature at about 50 to 60 degrees to obtain 2 - fluoro - 1 - nitrobenzene.
    Then, in the state of light, make 2 - fluoro - 1 - nitrobenzene with brominating agents such as N - bromosuccinimide (NBS) and initiator azobisisobutyronitrile (AIBN), and control the temperature at about 80 to 90 degrees to obtain 4 - (bromomethyl) - 2 - fluoro - 1 - nitrobenzene. In this process, it is necessary to ensure that the system is water-free and nitrogen-filled to protect.
    After purification, column chromatography can be used. Silica gel is used as the column material, and the mixture of petroleum ether and ethyl acetate is used as the eluent to obtain pure 4- (bromomethyl) -2 -fluoro-1-nitrobenzene. The yield is considerable and the quality is also good.
    Chemical Reactions & Modifications
    A derivative of benzene, 4 - (bromomethyl) - 2 - fluoro - 1 - nitro, its chemical changes and modifications are of great importance to our generation. The reaction of this compound is related to many chemical wonders. To make it modified, the reaction conditions and the selection of reagents must be studied in detail. In a specific reaction system, choose a suitable catalyst, or it can lead it to change in the desired direction. Or by changing factors such as temperature and pressure, observe its chemical response. Through various attempts, we hope to obtain the best reaction path to achieve effective modification of this compound, paving the way for subsequent research and application, enhancing the knowledge of chemistry, and contributing to the development of related fields.
    Synonyms & Product Names
    Today there is a substance called 4- (bromomethyl) -2 -fluoro-1 -nitrobenzene. This substance is very important in the field of chemistry. Its nicknames are also common, all of which are related to its properties and structure.
    Look at this substance, the benzene ring is the base, and bromomethyl, fluorine, and nitro are in their respective positions, echoing each other. Chemists regard it as a treasure because it is often used as a key raw material in the process of organic synthesis. Or used to create new drugs to treat human suffering; or to help develop new materials to add energy to the world.
    Although its name is a mouthful, it can often be expressed in terms that are easier to explain. In the field of chemistry, the name change is to facilitate communication and promote research, and the academic community is moving forward step by step on the road to exploring the mysteries of matter.
    Safety & Operational Standards
    About 4 - (bromomethyl) - 2 - fluoro - 1 - nitrobenzene product safety and operating specifications
    Fu 4 - (bromomethyl) - 2 - fluoro - 1 - nitrobenzene is a substance that is often encountered in chemical research. During its research and operation, safety regulations are of paramount importance.
    The first word is safety. This substance is dangerous to a certain extent, and it is especially harmful when it comes into contact with the skin or irritates the eyes. Therefore, when operating, you must wear protective clothing, goggles and gloves to prevent inadvertent contact. And its odor is pungent, or harmful to health, it is suitable for operation in a well-ventilated place. If conditions permit, use a fume hood to keep the ambient air fresh and avoid the harm of inhalation.
    Describe the operating specifications below. When weighing, use a precise instrument and weigh it carefully according to the amount required by the experiment, not more or less, so as not to affect the experimental results. When dissolving, choose a suitable solvent, add it slowly in an appropriate proportion, and stir it lightly with a glass rod to promote uniform dissolution. During the reaction process, pay close attention to temperature, time and other conditions, and operate according to the predetermined reaction process without unauthorized modification. After the reaction, the product treatment should not be ignored, or separated and purified according to chemical properties, and the waste must be sorted and disposed of according to regulations, and cannot be discarded at will to avoid polluting the environment.
    In short, in the research operation of 4 - (bromomethyl) - 2 - fluoro - 1 - nitrobenzene, it is necessary to strictly abide by safety and operation standards to ensure the smooth operation of the experiment and protect the personal safety of the research, so as not to cause accidents.
    Application Area
    Today there is a product called 4- (bromomethyl) -2-fluoro-1-nitrobenzene. This product is widely used in the field of chemical industry.
    It can be used as a key intermediate in the development of medicine. Through specific methods, it can be converted into drugs with unique curative effects, or for difficult diseases, to help health recovery.
    It is also indispensable in the process of material creation. It can be integrated into special materials to give the material properties such as enhanced stability and optimized optical properties, making the material suitable for high-end technology products, such as advanced display screens and precision optical instruments.
    In addition, in the preparation of fine chemicals, it is also an important raw material for the synthesis of additives with special functions, catalysts, etc., to promote the progress of related industries. Therefore, 4 - (bromomethyl) - 2 - fluoro - 1 - nitrobenzene is of critical value in many application fields.
    Research & Development
    In recent years, in the field of chemistry, I have focused on the study of "Benzene, 4- (Bromomethyl) -2-Fluoro-1-Nitro-". At first, analyzing its structure, we know how well its atoms are connected, and fluorine, bromine, nitro and other groups are in their respective positions and affect each other.
    Then explore its properties. It has different solubility in common solvents and unique chemical activity. Try different reaction conditions and observe the reactions it participates in. When high temperature and catalyst are present, it can change wonderfully with various reagents.
    After many experiments, a new method has been prepared, and the yield is higher than before. However, there are still challenges, such as the control of reaction by-products and the reduction of costs.
    Looking to the future, we hope to expand its application. Or it can be used to create new drugs that act on specific targets based on their structural characteristics; or it can add new ways to material synthesis and give new energy to materials with its characteristics. Continuous research, hoping that this product will shine in scientific research and industry, and promote the development of the chemical field.
    Toxicity Research
    Recently, this substance has been studied, and it is called "Benzene, 4- (Bromomethyl) -2-Fluoro-1-Nitro-". It is quite important for toxicity research. Looking at this substance, its structure contains bromomethyl, fluorine, nitro and other groups, or it may be potentially toxic.
    Taste the classics, such compounds containing halogen and nitro are mostly disturbing to living beings. It may enter the body through breathing and skin contact, causing damage to the organs and disordered qi and blood.
    We should carefully observe its toxicity in different environments and doses, or we can use animal experiments to observe its effects on the body, such as organ lesions, abnormal behavior, etc. In this way, the full picture of its toxicity can be obtained, providing evidence for future use or prevention, ensuring the well-being of everyone and protecting the peace of the environment.
    Future Prospects
    I am looking forward to the future of the compound "Benzene, 4- (Bromomethyl) -2-Fluoro-1-Nitro-". This compound has a unique structure, or it will shine brightly on the road of pharmaceutical research and development. Over time, it will definitely provide a new way to overcome difficult diseases. In the field of materials science, it may also open up a new situation and make the performance of materials more outstanding. Chemists should study diligently, explore unremitting, and use advanced technology and exquisite theory to dig deep into the potential of this compound. When the time comes, this compound will be like a pearl, contributing to future progress, achieving extraordinary things, and bringing many surprises and benefits to the world.
    Where to Buy Benzene, 4-(Bromomethyl)-2-Fluoro-1-Nitro- in China?
    As a trusted Benzene, 4-(Bromomethyl)-2-Fluoro-1-Nitro- manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading Benzene, 4-(Bromomethyl)-2-Fluoro-1-Nitro- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of this product 4- (bromomethyl) -2-fluoro-1-nitrobenzene?
    This is about the physical properties of a substance, namely 4- (hydroxymethyl) -2-ene-1-naphthyl mercaptan. This substance has unique physical properties. Its appearance may be crystalline, often white or nearly white fine crystals. Under light, the crystal texture can be seen, like fine jade. Its melting point is in a specific temperature range, about XX ° C. This temperature causes it to gradually melt from solid to liquid state. This property is crucial when identifying and purifying this substance.
    In addition, the solubility of this substance also has characteristics. In organic solvents such as ethanol and ether, it has a certain solubility and can be dissolved into a uniform dispersion system, just like sand entering water flow, quietly melting. However, in water, the solubility is not good. Due to the hydrophobic part of its molecular structure, it is difficult to be affectionate with water molecules, so it is mostly suspended or precipitated in water.
    Its density is also an important physical property, heavier than water. When placed in water, such as a stone sinking abyss, it sinks directly. And it has a certain volatility. In the air, although it is slow, it can be detected that its odor is emitted. The smell is unique, like a light sulfur fragrance, mixed with a little fresh vegetation. This volatility should be paid attention to when storing to prevent material dissipation and environmental odor.
    In addition, the stability of the substance is good at room temperature and pressure, and it can be stored stably. In case of special conditions such as high temperature and strong oxidizing agent, the structure is changeable, or a chemical reaction is initiated, resulting in the change of its physical properties. This is a brief description of some physical properties of the substance 4- (hydroxymethyl) -2-ene-1-naphthyl mercaptan.
    What are the chemical properties of 4- (bromomethyl) -2-fluoro-1-nitrobenzene?
    4- (hydroxymethyl) -2 -pentene-1 -aldehyde, this is an organic compound. Its chemical properties are quite unique, and the following are described in detail by Jun.
    From the structural point of view, the compound contains functional groups such as carbon-carbon double bonds, aldehyde groups and hydroxymethyl groups. The carbon-carbon double bonds give it unsaturation, so it can undergo an addition reaction. In case of bromine water, it can be added with it, causing bromine water to fade; under suitable catalysts and conditions, it can be added with hydrogen to form saturated compounds. The existence of
    aldehyde groups also gives it unique chemical properties. It can react with silver ammonia solution in an alkaline environment to form a bright silver mirror. This reaction is often used for aldehyde group testing. It can also react with new copper hydroxide suspensions to produce brick red precipitation when heated. This is one of the characteristic reactions of aldose.
    In addition, the hydroxyl group in the hydroxymethyl group also has corresponding activity. It can esterify with carboxylic acids, catalyzed by concentrated sulfuric acid and heated under conditions to form esters and water. There are hydrogen atoms on the ortho-carbon of the carbon atom attached to the hydroxyl group, so a elimination reaction can occur to eliminate a molecule of water and form a compound containing double bonds.
    This compound has a wide range of applications in the field of organic synthesis due to its various active functional groups. It can be used as a raw material to synthesize many complex organic compounds, and is of great significance in the pharmaceutical, materials and other industries.
    What is the main use of 4- (bromomethyl) -2-fluoro-1-nitrobenzene?
    The main use of (cyanomethyl) 2-ether-1-carbonylbenzene is related to various chemical synthesis fields.
    In the field of organic synthesis, this compound is often used as a key intermediate. Its cyanomethyl part has high reactivity and can be combined with various nucleophiles through many reaction pathways, such as nucleophilic substitution reactions. The existence of ether bonds endows the molecule with specific solubility and stability. In the synthesis process, it can help maintain the stability of the reaction system and reserve various possibilities for subsequent functional group transformation. The carbonylbenzene structure also provides rich reaction check points and can participate in reactions such as condensation and addition reactions.
    For example, in some drug synthesis processes, (cyanomethyl) 2-ether-1-carbonylbenzene can be used as a starting material. By nucleophilic substitution, cyanomethyl can be introduced into a specific structure, and then modified by carbonyl reaction to gradually build a complex drug molecular skeleton. Or in the field of fine chemical preparation, using its structural characteristics, through a series of reactions, material additives with special properties can be synthesized.
    In the field of materials science, based on this compound, new polymer materials can be constructed through polymerization or other cross-linking means. Its unique structure endows the material with specific physical and chemical properties, such as improving the heat resistance and mechanical properties of the material.
    In addition, (cyanomethyl) 2-ether-1-carbonylbenzene can be used as an important structural unit in the synthesis of dyes. Through appropriate functional group modification and coupling reaction, dyes with bright colors and good stability can be synthesized. The synergistic action of different parts in the structure has a significant impact on the key indicators such as color performance and light resistance of the dye.
    What is the preparation method of 4- (bromomethyl) -2-fluoro-1-nitrobenzene?
    To prepare 4- (hydroxymethyl) -2-ene-1-carboxypyridine medicine, the method is as follows:
    First take the appropriate pyridine compound as the starting material. In a suitable reaction vessel, add the pyridine derivative, dissolve it with an appropriate amount of organic solvent, such as dichloromethane, N, N-dimethylformamide, etc., so that the material is uniformly dispersed.
    Then, in a low temperature environment, such as in an ice-water bath, slowly drop the hydroxymethylation reagent, such as a mixed system of paraformaldehyde and a suitable catalyst, such as triethylamine as the catalyst. The dropwise addition process requires a slow and uniform speed, and constant stirring is required to fully mix the reaction system to avoid local overheating or uneven reaction. After the dropwise addition is completed, the temperature is gradually raised to room temperature, and the reaction number is continued to be stirred. During this process, a hydroxymethylation reaction will occur at a specific position of the pyridine ring to generate the corresponding hydroxymethylpyridine-containing intermediate.
    Next, the intermediate is alkylated. Take another reaction vessel, transfer the obtained intermediate to it, add an alkylation reagent, such as an alkenyl halide, and add an appropriate amount of base, such as potassium carbonate, to promote the reaction. The reaction is carried out under heated reflux conditions and maintained for a certain period of time, so that the alkenyl group is successfully introduced into the appropriate position of the pyridine ring to generate the 4- (hydroxymethyl) -2-alkenopyridine intermediate.
    Finally, the carboxylation step is carried out. The intermediate is placed in a suitable reaction environment, and a carboxylation reagent is added, such as carbon dioxide gas reacting with the intermediate in the presence of a phase transfer catalyst, or other suitable carboxylation methods are used, such as rehydrolysis with halocarboxylic acid esters and intermediates. After a series of reaction operations, the target product 4- (hydroxymethyl) -2-ene-1-carboxylpyridine can be obtained. During the entire process, it is necessary to closely monitor the reaction process, and use thin-layer chromatography, liquid chromatography, and other means to track the reaction to ensure that each step of the reaction achieves the desired effect, and the purity and yield of the product meet the requirements.
    What are the precautions for 4- (bromomethyl) -2-fluoro-1-nitrobenzene during storage and transportation?
    4 - (hydroxymethyl) -2 -pentene-1 -aldehyde naphthalene should pay attention to the following things during storage and transportation:
    First, this material has certain chemical activity and is quite sensitive to environmental conditions. When storing, choose a dry, cool and well-ventilated place. High humidity can easily cause deliquescence or cause chemical reactions, and high temperature may accelerate its decomposition and deterioration, so avoid high temperature and humidity.
    Second, during transportation, be sure to ensure that the packaging is tight and stable. Due to its chemical structure, if the packaging is damaged, it is easy to react with external substances, which not only damages its own quality, but also may endanger transportation safety. Packaging materials should be selected that can effectively isolate air and water vapor.
    Third, this compound is more sensitive to light. Light may induce luminescent chemical reactions, affecting its stability and quality. Whether it is storage or transportation, all efforts should be made to avoid light, and opaque packaging materials can be used, or stored in dark places.
    Fourth, in view of its chemical properties, it is necessary to keep away from fire sources, oxidants, etc. Because of its flammability, in case of open flames, hot topics or oxidants, there is a risk of combustion and explosion. In storage and transportation sites, corresponding fire protection facilities and emergency treatment equipment should be equipped, just in case.
    Fifth, the handling process should be handled with care. Violent vibration or impact may damage its structure, resulting in changes in chemical properties, which in turn affect the performance of use. Operators also need to undergo professional training to be familiar with their characteristics and safe operation practices.