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What is the Chinese name of Benzene, 4-Bromo-1-Iodo-2- (Trifluoromethyl) -?
This is a question about the naming of organic compounds. According to the tradition of "Chemical Products", the naming of organic compounds follows a certain rule.
For "Benzene, 4 - Bromo - 1 - Iodo - 2 - (Trifluoromethyl) -", the main structure is the benzene ring. Above the benzene ring, there are many substituents. "4 - Bromo" means that the 4th carbon position of the benzene ring is connected with a bromine atom; "1 - Iodo" means that the 1st carbon position is connected with an iodine atom; "2- (Trifluoromethyl) " Table 2 carbon position is connected with a trifluoromethyl.
According to the traditional naming convention, the substituents should be listed first, and then the main structure should be described. The order in which the substituents are listed is based on their atomic number, with the smaller being the first. The atomic number of bromine (Br) is less than that of iodine (I), and trifluoromethyl (-CF) also has its specific order.
Therefore, the Chinese name of this compound is: 4-bromo-1-iodine-2 - (trifluoromethyl) benzene. This naming not only conforms to the rules passed down in "Chemical Engineering", but also accurately shows the structural characteristics of the compound, so that industry insiders can know its approximate structure after hearing its name, which is of great significance in chemical research and practice.
What are the physical properties of Benzene, 4-Bromo-1-Iodo-2- (Trifluoromethyl) -?
4-Bromo-1-iodine-2- (trifluoromethyl) benzene, this is an organic compound. Depending on its physical properties, it is usually liquid at room temperature and pressure, but the specific state may change due to surrounding environmental factors. Its color is nearly colorless, or slightly yellowish, and the transparency is quite high.
Regarding the melting point, due to its intermolecular forces and structural characteristics, the melting point is about -20 ° C, and the boiling point is roughly in the range of 180-190 ° C. The lower melting point is due to the introduction of trifluoromethyl, bromine and iodine atoms into the molecular structure, which results in relatively weakened intermolecular forces, making it easier to convert from solid to liquid; the higher boiling point is due to the increase in molecular mass and the enhancement of intermolecular van der Waals forces by halogen atoms.
Its density is greater than that of water, about 2.1-2.3g/cm ³. If placed in water, it will sink to the bottom. In terms of solubility, it has little solubility in polar solvents such as water. Due to its strong non-polar molecular structure, the polarity difference with water is significant, and it follows the principle of "similar miscibility". However, in common organic solvents, such as ether, chloroform, dichloromethane, and other non-polar or weakly polar solvents, the solubility is quite good, and it can be well miscible with them.
In addition, the compound is volatile and will slowly evaporate in the air, emitting a special odor. And because it contains halogen atoms and trifluoromethyl, it has different chemical stability. Under specific conditions, it can participate in a variety of chemical reactions and exhibit unique chemical properties.
What are the chemical properties of Benzene, 4-Bromo-1-Iodo-2- (Trifluoromethyl) -?
This is 4-bromo-1-iodine-2 - (trifluoromethyl) benzene, which has the general characteristics of aromatics in terms of chemical properties.
From the perspective of electrophilic substitution reaction, the electron cloud density of the benzene ring has a significant effect. Because trifluoromethyl is a strong electron-absorbing group, it will reduce the electron cloud density of the benzene ring, and the electrophilic substitution reaction activity is lower than that of benzene. And this group reduces the electron cloud density of the ortho-and para-site of the benzene ring more than the meta-site, so the electrophilic substitution reaction mainly occurs in the meta-site. For example, during nitrification, the nitro group mainly enters the meta-site to obtain the meta-substitution product.
In terms of the characteristics of halogen atoms, although bromine and iodine are ortho and para-localizers, the electron cloud density of the benzene ring can increase in the ortho and para-localizers, and the electrophilic substitution reaction activity of the benzene ring can be enhanced. However, due to the combined effect of steric hindrance and electronic effect, the localization effect may be slightly deviated from the theory in some reactions.
In terms of oxidation reaction, the compound is more difficult to be oxidized. Due to the strong electron absorption of trifluoromethyl, the benzene ring structure is stabilized, making it difficult to be oxidized by common oxidants. However, under certain harsh conditions, such as high temperature and strong oxidants, the benzene ring may be destroyed.
In addition, the halogen atoms it contains can participate in nucle Under appropriate nucleophilic reagents and reaction conditions, bromine or iodine atoms can be replaced by nucleophilic reagents to form corresponding replacement products. In this process, the tendency of halogen atom departure is related to the activity of halogen atoms. Usually, iodine atoms are more likely to leave than bromine atoms, because the bond energy of C-I bond is less than that of C-Br bond.
What is the main use of Benzene, 4-Bromo-1-Iodo-2- (Trifluoromethyl) -?
4-Bromo-1-iodine-2- (trifluoromethyl) benzene is an organic compound. It has a wide range of uses and is a key intermediate in the field of organic synthesis.
In the field of medicinal chemistry, it can be used to construct complex molecular structures with specific physiological activities. For example, its side chains can be connected to active functional groups through a series of organic reactions, thus creating new drug molecules and providing more possibilities for drug development.
In the field of materials science, it also plays an important role. With its unique chemical structure and properties, it can be used to prepare special functional materials. Such as fluoropolymer materials, which can improve the chemical stability, weather resistance and surface properties of materials. After rational design and reaction, it can become the structural unit of the polymer, endowing the material with unique properties and meeting the requirements of material properties in different application scenarios.
Furthermore, in the preparation of fine chemical products, 4-bromo-1-iodine-2 - (trifluoromethyl) benzene can be used as a starting material to synthesize high-value-added fine chemicals through multi-step reactions, such as special fragrances, pigments, etc., to meet the market demand for high-quality fine chemical products.
Overall, although 4-bromo-1-iodine-2- (trifluoromethyl) benzene is an organic compound, it plays an indispensable role in many fields such as medicine, materials, and fine chemicals, promoting the sustainable development and innovation of related fields.
What are the preparation methods of Benzene, 4-Bromo-1-Iodo-2- (Trifluoromethyl) -
There are various ways to prepare 4-bromo-1-iodine-2- (trifluoromethyl) benzene.
First, it can be started from a suitable aromatic hydrocarbon substrate. Based on aromatic hydrocarbons containing trifluoromethyl, bromine atoms are introduced first. This can be achieved by interacting with brominating reagents under appropriate reaction conditions. If liquid bromine is used as a bromine source, under the catalysis of Lewis acids (such as iron tribromide), aromatics can undergo electrophilic substitution reactions to introduce bromine atoms at specific positions in aromatic rings. This step requires attention to the reaction temperature and reagent ratio to prevent the formation of polybrominated products.
Next, iodine atoms are introduced. A halogen atom exchange reaction can be used to react with a suitable iodine substitution reagent (such as potassium iodide, etc.) in a specific organic solvent (such as N, N-dimethylformamide, etc.) under heating conditions. In this process, the halogen atom is substituted, so that the iodine atom is connected to the aromatic ring, thereby obtaining 4-bromo-1-iodine-2 - (trifluoromethyl) benzene.
Second, it can also be used to gradually build an aromatic ring. First prepare an intermediate containing trifluoromethyl and bromine atoms, and then introduce iodine atoms at the same time through a suitable cyclization reaction. If an unsaturated compound containing trifluoromethyl and bromine atoms is used as a raw material, an iodine source is added to the reaction system through cyclization reaction, and an aromatic ring structure is constructed through multi-step reaction. At the same time, the layout of bromine, iodine and trifluoromethyl based on the specific position of the benzene ring is achieved.
To prepare this compound, an appropriate method is selected according to various factors such as the availability of raw materials, the ease of control of reaction conditions and cost, so as to achieve the purpose of efficient and economical synthesis.