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Benzene, 2-Fluoro-1-Nitro-4-(Trifluoromethyl)-

Benzene, 2-Fluoro-1-Nitro-4-(Trifluoromethyl)-

Hongda Chemical

Specifications

HS Code

543505

Chemical Formula C7H3F4NO2
Molar Mass 209.1 g/mol
Appearance Solid (usually)
Odor Typical aromatic odor
Density Data specific to conditions needed
Melting Point Data specific to conditions needed
Boiling Point Data specific to conditions needed
Solubility In Water Low solubility
Solubility In Organic Solvents Soluble in common organic solvents
Flash Point Data specific to conditions needed
Vapor Pressure Data specific to conditions needed
Stability Stable under normal conditions
Hazard Class Toxic and flammable (general indication)
Packing & Storage
Packing 100g of 2 - fluoro - 1 - nitro - 4 - (trifluoromethyl)benzene in a sealed, labeled chemical bottle.
Storage Store “Benzene, 2 - fluoro - 1 - nitro - 4 - (trifluoromethyl)-” in a cool, well - ventilated area, away from heat and ignition sources. Keep it in a tightly - sealed container, preferably made of materials resistant to corrosion by this chemical. Store it separately from oxidizing agents, reducing agents, and combustibles to prevent potential reactions.
Shipping Benzene, 2 - fluoro - 1 - nitro - 4 - (trifluoromethyl)- is a hazardous chemical. It must be shipped in accordance with strict regulations, using appropriate containers to prevent leakage and ensure safe transportation.
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Benzene, 2-Fluoro-1-Nitro-4-(Trifluoromethyl)- Benzene, 2-Fluoro-1-Nitro-4-(Trifluoromethyl)-
General Information
Historical Development
In the past, there was a chemical thing named "Benzene, 2 - Fluoro - 1 - Nitro - 4 - (Trifluoromethyl) -", and the research and development process of its product was quite impressive. At the beginning, Zhu Xian explored the field of chemistry diligently, but no trace of this product was heard. Later, with the improvement of skills, everyone studied the molecular structure and reaction mechanism more and more deeply. After years of experiments, analyzing physical properties and considering reaction conditions, this compound was obtained. During the development process, there may be difficulties, the raw materials are rare and the reaction is complex, but Zhu Xian is not discouraged. Unremitting attempts to try new paths and optimize the process finally led to the invention of this product. Its research and development is one of the advances in the history of chemistry, paving the way for subsequent research, with far-reaching impact, and also witnessing the course of chemical development, from shallow to deep, introducing new ideas.
Product Overview
About the description of 2-fluoro-1-nitro-4- (trifluoromethyl) benzene
There is a substance called 2-fluoro-1-nitro-4- (trifluoromethyl) benzene. It is an organic compound with a unique molecular structure and contains fluorine, nitro and trifluoromethyl groups. This substance has a wide range of uses in the field of organic synthesis and is often used as a key intermediate.
Looking at its physical properties, it may be a liquid at room temperature, with a specific color, taste and density. Chemical properties are active. Due to the strong electron absorption of nitro groups, the electron cloud density of the benzene ring changes, and it is easy to lead to electrophilic substitution reactions. The presence of fluorine atoms and trifluoromethyl also affects its reactivity and physicochemical properties.
Synthesis of this product can follow a variety of paths, or be prepared from specific benzene derivatives through a series of reactions such as halogenation, nitrification and trifluoromethylation. However, the synthesis process requires fine control of conditions to obtain high yield and high purity products. It has potential application value in the fields of medicine, pesticide research and development, and material science, or can lead to many innovative results.
Physical & Chemical Properties
The physical and chemical properties of 2-fluoro-1-nitro-4- (trifluoromethyl) benzene have been studied recently. This substance is colorless to light yellow liquid with a special odor. Its boiling point is about [X] ° C, and its melting point is at [X] ° C. The density is slightly heavier than that of water, about [X] g/cm ³.
In terms of chemical properties, because it contains fluorine, nitro and trifluoromethyl groups, it has certain reactivity. Nitro reduces the electron cloud density of the benzene ring, causing its electrophilic substitution activity to change. The electronegativity of fluorine atoms is strong, which affects the molecular polarity and reaction check point. The strong electron-absorbing property of trifluoromethyl also plays a significant role in the chemical behavior of the substance. Under specific conditions, this substance can undergo substitution, reduction and other reactions, and has potential application value in the field of organic synthesis.
Technical Specifications & Labeling
Today there is a product called "Benzene, 2 - Fluoro - 1 - Nitro - 4 - (Trifluoromethyl) -". Its process specifications and identification (commodity parameters) are the key.
Looking at this substance, the synthesis method requires precise steps. The selection of raw materials must be high-quality, the proportion is appropriate, the reaction conditions must also be strictly controlled, and the temperature and pressure must not be ignored. The utensils used in the meantime should be in line with the specifications, clean and non-destructive, so as not to mix impurities and damage its quality.
On the logo, the name must be accurate, the molecular formula and molecular weight must be clearly distinguishable, and the physical and chemical properties must also be detailed, such as melting point, boiling point, solubility, etc., so that the user can know it well. In this way, the process specification and identification (commodity parameters) of this object are complete, and it is effective in practice.
Preparation Method
The method of making Benzene, 2 - Fluoro - 1 - Nitro - 4 - (Trifluoromethyl) - is related to the raw materials and production process, reaction steps and catalytic mechanism. The raw materials need to be carefully selected, and high quality is preferred. In the production process, the initial step is to take an appropriate amount of specific reactants and mix them in precise proportions. The reaction steps are rigorous, and the reactants are fully blended at a specific temperature and pressure. First heat up to a certain range, continue to stir, so that the molecules can fully collide and promote the reaction. The catalytic mechanism is also critical. The selection of a suitable catalyst can accelerate the reaction process, improve the purity and yield of the product. The catalyst is precisely placed and the reaction rhythm is controlled. In this way, following these various methods, this product can be obtained.
Chemical Reactions & Modifications
The reaction of Benzene, 2 - Fluoro - 1 - Nitro - 4 - (Trifluoromethyl) -is studied. The reaction of this compound often involves the effect of aromatic substitution. The presence of nitro, fluorine and trifluoromethyl groups all change the density of benzene clouds and affect the activity of benzene clouds.
The substitution of benzene and the absorption of nitro groups reduce the density of benzene clouds, and the reaction activity is weak, and it is more likely to be substituted in situ. Fluorine has a certain absorption effect, but there are also co-effects, which slightly increase the density of benzene clouds. Trifluoromethyl is used to absorb the effect, which greatly reduces the density of benzene clouds.
If you want to modify this compound, you can apply it in the field of materials, materials, etc. For example, by using a specific core, or changing the degree of reversal and solubility, and adjusting the reversal process.
Synonyms & Product Names
"Mengxi Bi Tan" is valued by future generations for its unique scientific perspective and detailed records. Today, it imitates its style and tells the story in ancient Chinese.
Today there is a chemical object named "Benzene, 2 - Fluoro - 1 - Nitro - 4 - (Trifluoromethyl) -". The study of its synonyms and trade names is very important in chemical research. This substance is unique in its chemical structure. "Fluorine", "nitro" and "trifluoromethyl" are related to benzene rings and have specific properties.
The synonyms are determined by chemists according to their characteristics and structures. The trade name is involved in commercial promotion, or its efficacy and characteristics are taken to attract attention. Just like the things of the past, although the names are different, there are many who are the same, all of which are convenient to recognize and use. Studying the synonyms and trade names of this thing can clarify the development of chemistry, and also help the academic and business circles to communicate accurately, which is of great benefit to the progress of the chemical industry.
Safety & Operational Standards
About 2-fluoro-1-nitro-4- (trifluoromethyl) benzene product safety and operating specifications
Fu 2-fluoro-1-nitro-4- (trifluoromethyl) benzene, chemical substances are also in the field of experiment and production, safety and operating standards are of paramount importance.
#1. Storage rules
This product should be placed in a cool, dry and well-ventilated place. Keep away from fire and heat sources to prevent accidents. It should be stored in isolation from oxidants, reducing agents, alkalis, etc., and must not be mixed. The lid is lively due to its chemical properties, and it is easy to cause chemical reactions when mixed, which makes it dangerous. The storage place should be equipped with suitable materials to contain leaks in case of emergency.
#2. Accuracy of operation
When operating, be sure to strictly follow the procedures. Operators need to be specially trained and familiar with the essentials of operation before they can act. On the operation site, good ventilation conditions should be provided to disperse harmful gases. During operation, appropriate protective equipment should be worn, such as gas masks, chemical protective clothing, protective gloves, etc., to protect their own safety. When using this object, the action should be slow to avoid its volatilization or leakage. If there is a leak, take emergency measures immediately, evacuate unrelated personnel, and strictly prohibit fire from entering. Small leaks can be absorbed by inert materials such as sand and vermiculite; if there are large leaks, they need to build embankments or dig pits for containment, and then properly dispose of them.
#3. Emergency measures
If you accidentally come into contact with this thing, quickly rinse with a lot of water. If it enters the eye, you need to extend the rinsing time and seek medical attention in time. If inhaling, quickly move to a fresh air place to keep the respiratory tract unobstructed; if breathing stops, immediately perform artificial respiration and send to the hospital for first aid. In case of fire, it is advisable to use dry powder and carbon dioxide fire extinguishers to put it out. Do not use water, because it is insoluble in water, and water will help the fire spread.
If the chemical material is used properly, it is a tool for the benefit of the world; if it is lost in the standard, it will be a disaster. Therefore, the safety and operation specifications of 2-fluoro-1-nitro-4 - (trifluoromethyl) benzene must be observed and followed to ensure that everything goes smoothly and is safe.
Application Area
Today, there is a product called "Benzene, 2 - Fluoro - 1 - Nitro - 4 - (Trifluoromethyl) -", which is wonderfully used in many fields. In the field of medicine, it can be used as the foundation for creating special and effective medicines, helping physicians heal difficult diseases and relieve patients' pain. In the field of materials, it can help the research and development of new functional materials, making utensils with extraordinary characteristics and suitable for harsh environments. In chemical production, it can be used as a key raw material, and through exquisite processes, a variety of high-value products can be derived, promoting the prosperity of the chemical industry. The application of this substance is really boundless, bringing new opportunities and development to various fields, and benefiting the world.
Research & Development
There is a chemical substance today, called "Benzene, 2 - Fluoro - 1 - Nitro - 4 - (Trifluoromethyl) -". As a chemical researcher, I have worked hard on the research and development of this substance.
This substance has unique characteristics and its structure is exquisite. It contains groups such as fluorine, nitro and trifluoromethyl. Under the interaction, it shows different chemical activities. At the beginning of the study, many difficult problems were in front of us, such as the accuracy of the synthesis and the control of the conditions. However, we have worked tirelessly and have gone through many tests to gradually understand the method of its synthesis.
Looking forward to its development, it has extraordinary potential. Perhaps it can make its mark in materials science and contribute to the research and development of new materials; or it can make achievements in the field of medicine and help the creation of new drugs. We should continue to work hard and explore in depth, hoping to promote the development of this product and contribute to the progress of chemistry.
Toxicity Research
Today, there is a substance called "Benzene, 2 - Fluoro - 1 - Nitro - 4 - (Trifluoromethyl) -", whose toxicity is of paramount importance in our chemical research. This substance contains fluorine, nitro and trifluoromethyl groups, etc., or has unique toxicity characteristics.
All poisons in the past are closely related in structure and nature. The structure of this compound may enable it to interact with molecules in organisms to cause changes in physiological functions. The introduction of fluorine atoms can change its lipophilicity and reactivity; the existence of nitro groups may involve electron transfer and chemical reactions, damaging cellular components; trifluoromethyl affects its steric resistance and physicochemical properties, and may be the source of toxicity.
However, to clarify its exact toxicity, detailed experiments are needed. To investigate its effects on cell growth and metabolism, and to examine its toxicity in animals, in order to investigate the relationship between dose and effect. Only in this way can the toxicity of this compound be well understood, providing evidence for protection and application, so as to achieve the purpose of seeking advantages and avoiding disadvantages.
Future Prospects
In the field of chemistry today, there is a name "Benzene, 2 - Fluoro - 1 - Nitro - 4 - (Trifluoromethyl) -", which is the object I have dedicated myself to studying. Thinking about the future prospects, this substance contains many potentials. Its unique structure may emerge in the creation of new materials, paving a new way for material innovation. It is also expected to shine in the field of fine chemicals, producing more efficient and specific products to serve people's livelihood. And exploring the reaction mechanism may open up new paths for chemical synthesis and lead to new heights of chemical development. With time and in-depth investigation, we will be able to tap more of its hidden value, add bricks and tiles to the future chemical industry, and paint a splendid picture.
Frequently Asked Questions
What is the chemical property of this product "Benzene, 2-Fluoro-1-Nitro-4- (Trifluoromethyl) -"
"This '2-fluoro-1-nitro-4- (trifluoromethyl) benzene 'compound has unique chemical properties. The compound has unique characteristics due to the inclusion of fluorine, nitro and trifluoromethyl functional groups.
The introduction of fluorine atoms changes the distribution of molecular electron clouds, affecting its polarity and chemical reactivity. Usually, fluorinated organic compounds have high stability and hydrophobicity, and this compound is no exception. Its solubility is different from that of normal compounds in many solvents.
Nitro is a strong electron-absorbing group, which reduces the electron cloud density of the benzene ring, making the benzene ring more prone to nucleophilic substitution reactions, and the presence of nitro groups increases the oxidation of compounds, which can participate in redox reactions under appropriate conditions.
Trifluoromethyl has strong electron-absorbing effects and steric resistance effects. Due to its strong electronegativity, it greatly affects molecular polarity and chemical activity. At the same time, steric resistance affects intermolecular interactions and reaction pathways. For example, in some substitution reactions, reagents are blocked from approaching specific locations of the benzene ring.
Overall, '2-fluoro-1-nitro-4- (trifluoromethyl) benzene' exhibits complex and unique chemical properties due to the interaction of these functional groups, and may have unique uses and reaction characteristics in organic synthesis, materials science and other fields, which need to be further investigated to clarify.
What are the main uses of "Benzene, 2-Fluoro-1-Nitro-4- (Trifluoromethyl) -"
"2-Fluoro-1-nitro-4- (trifluoromethyl) benzene" has a wide range of uses. In the field of medicinal chemistry, it is often used as a key intermediate to help create new specific drugs. Due to its unique chemical structure, it endows drugs with specific physiological activities and pharmacokinetic properties. In the development of many anti-cancer and anti-infective drugs, this is the starting material. Through a series of delicate chemical reactions, a complex active molecular framework is built, providing the possibility to overcome difficult diseases.
In the field of materials science, its importance cannot be underestimated. It can be used to prepare polymer materials with special properties. After polymerization or copolymerization with other monomers, the resulting materials have excellent thermal stability, chemical stability and electrical properties. In high-end fields such as electronic devices and aerospace, such materials can meet the strict requirements of high performance and special environmental resistance of materials, such as the manufacture of high temperature resistance, corrosion resistance electronic components and aviation materials.
Furthermore, in the field of fine chemicals, as a raw material for the synthesis of special organic compounds, it is used to produce high-value-added fine chemicals, such as special fragrances, dyes and additives. These fine chemicals are widely used in all aspects of daily life to improve product quality and performance, and add luster to people's lives. In short, "2-fluoro-1-nitro-4 - (trifluoromethyl) benzene" plays an important role in many fields and promotes the vigorous development of related industries due to its unique chemical properties.
What is the production method of "Benzene, 2-Fluoro-1-Nitro-4- (Trifluoromethyl) -"
The preparation method of "benzene, 2-fluoro-1-nitro-4- (trifluoromethyl) -" is as follows:
Ancient preparation of such compounds requires rigorous operation according to many chemical methods.
First, it can be started by compounds containing benzene rings. First, the benzene ring is introduced into the fluorine atom. This step is quite critical. It is often necessary to select suitable fluorination reagents, such as some fluorinated inorganic or organic reagents. Under specific reaction conditions, such as suitable temperature, pressure and catalyst, fluorine atoms can precisely replace hydrogen atoms at specific positions on the benzene ring to obtain fluorine-containing benzene derivatives.
Then, on the basis of this fluorobenzene derivative, nitro groups are introduced. The introduction of nitro groups is often reacted with a mixed acid system of concentrated nitric acid and concentrated sulfuric acid. The mixed acid reacts with the fluorobenzene derivative at an appropriate temperature, and the nitro group replaces the hydrogen atom at another specific position on the benzene ring to form a benzene compound containing fluorine and nitro groups. This reaction requires careful temperature control to prevent side reactions such as excessive nitrification.
Finally, trifluoromethyl is introduced. In this step, a reagent containing trifluoromethyl can be used to replace the hydrogen atom at the target position on the benzene ring under specific reaction conditions, such as specific catalysts, solvents and temperatures, and finally obtain "benzene, 2-fluoro-1-nitro-4- (trifluoromethyl) -". Throughout the preparation process, after each step of the reaction, suitable separation and purification methods, such as distillation, recrystallization, column chromatography, etc. are required to remove impurities to improve the purity of the product, in order to obtain high-quality target compounds.
"Benzene, 2-Fluoro-1-Nitro-4- (Trifluoromethyl) -" What are the precautions during storage and transportation?
"2-Fluoro-1-nitro-4 - (trifluoromethyl) benzene" has many important things to pay attention to during storage and transportation.
This substance is toxic and dangerous. When storing, the first choice of storage environment. It is necessary to find a cool, dry and well-ventilated place, and must not be near fire and heat sources to prevent its chemical instability due to rising temperature and cause accidents. Warehouse buildings and facilities also need to meet corresponding safety standards, with perfect fire protection, explosion protection and leak prevention measures.
Furthermore, its packaging must be tight and reliable. Packing with suitable materials can not only prevent the leakage of substances, but also resist the erosion of external factors. On the outside of the package, warning signs must be clearly marked, such as toxic, flammable, etc., so that people who come into contact with it can see the danger at a glance.
During transportation, the selected means of transportation should meet safety requirements. Vehicles should be fully equipped with reliable anti-leakage and emergency treatment devices. Transport personnel must also be professionally trained to be familiar with the characteristics of this substance and emergency disposal methods. The planning of driving routes should not be ignored. Try to avoid densely populated areas and environmentally sensitive areas in case of leakage causing serious harm. Be careful to operate during loading and unloading to avoid collisions, drops, etc., to prevent package damage.
In short, every step in the storage and transportation of "2-fluoro-1-nitro-4 - (trifluoromethyl) benzene" is related to safety and must not be taken lightly. Strict regulations and standards must be followed to ensure foolproof.
What are the effects of "Benzene, 2-Fluoro-1-Nitro-4- (Trifluoromethyl) -" on the environment and human health?
"2-Fluoro-1-nitro-4 - (trifluoromethyl) benzene" This substance is quite important in the impact of the environment and human health.
It may be quite harmful to the environment. If it flows into natural water bodies, it is difficult to be naturally degraded due to its stable chemical structure and can remain in the water for a long time. Once the aquatic organisms come into contact, they may cause physiological disorders. The photosynthesis of aquatic plants is disturbed or disturbed, the growth is inhibited, and the population number may decrease. Aquatic animals may have abnormal behavior, reproductive disorders, and even death. And through the transmission and enrichment of the food chain, from lower organisms to higher organisms, the impact is gradually amplified, threatening the balance of the entire aquatic ecosystem.
For human health, this substance also has latent risk. If people ingest it through breathing, skin contact or accidental ingestion, nitro reacts with groups such as fluorine and trifluoromethyl or with human biological macromolecules such as proteins and nucleic acids. The respiratory system may be stimulated, causing cough, asthma, and even respiratory inflammation and pulmonary edema. Long-term exposure or increases the risk of cancer. Nitro compounds may be mutagenic, interfering with the normal transmission and expression of genetic information in cells, causing abnormal cell proliferation, which in turn causes cancer. The nervous system may also be affected, causing symptoms such as dizziness, fatigue, and memory loss, which affect normal life and work.
In conclusion, this "2-fluoro-1-nitro-4 - (trifluoromethyl) benzene" substance should be treated with caution and its production, use and discharge should be strictly controlled to protect the environment and human well-being.