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Benzene, 2-Fluoro-1-Iodo-3-Methyl-

Benzene, 2-Fluoro-1-Iodo-3-Methyl-

Hongda Chemical

Specifications

HS Code

367609

Chemical Formula C7H6FI
Molar Mass 236.025 g/mol
Appearance Typically a colorless to pale - yellow liquid
Boiling Point Approximately in the range of 180 - 200 °C (estimation based on similar halogenated aromatic compounds)
Density Estimated to be around 1.8 - 2.0 g/cm³ (based on related halogenated benzenes)
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform, and ethyl acetate
Vapor Pressure Low at room temperature

As an accredited Benzene, 2-Fluoro-1-Iodo-3-Methyl- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 2 - fluoro - 1 - iodo - 3 - methyl benzene in a sealed chemical - grade bottle.
Storage Store “Benzene, 2 - fluoro - 1 - iodo - 3 - methyl -” in a cool, well - ventilated area, away from heat, sparks, and open flames as it is likely flammable. Keep it in a tightly sealed container to prevent vapor release. Store it separately from oxidizing agents and incompatible substances to avoid potential reactions. Ensure the storage area has spill - containment measures in place.
Shipping Shipping of 2 - fluoro - 1 - iodo - 3 - methyl benzene, a potentially hazardous chemical, requires proper packaging in accordance with regulations. It should be shipped in containers suitable for chemicals, labeled clearly, and transported with safety protocols for such substances.
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Benzene, 2-Fluoro-1-Iodo-3-Methyl- Benzene, 2-Fluoro-1-Iodo-3-Methyl-
General Information
Historical Development
In the past, in the field of organic chemistry, many secrets of compounds have yet to be revealed. Benzene, 2 - Fluoro - 1 - Iodo - 3 - Methyl - This compound has also been around for years. At the beginning, chemists focused on various reactions in the laboratory, wanting to explore new combinations of substances. At that time, conditions were limited and the instruments were not as sophisticated as they are today, but the heart of exploration was not reduced.
After repeated experiments, relevant clues were occasionally obtained, and everyone focused on a specific reaction path. After unremitting research, the structure and properties of the compound were gradually recognized. Over time, the technology improved, the preparation method of the compound was optimized, and the yield increased. Its application in the field of organic synthesis has also become increasingly widespread, contributing to the development of chemistry and leaving a deep imprint on the path of exploration in the past.
Product Overview
Product Overview
There is a compound called "2-fluoro-1-iodine-3-methylbenzene". It is an organic compound with a unique chemical structure. On the benzene ring, fluorine atoms, iodine atoms and methyl atoms are arranged in one side, orderly.
This compound is of great significance in the field of organic synthesis. The introduction of fluorine atoms can change the electron cloud distribution of compounds and affect their physical and chemical properties. Iodine atoms are highly active and can be used as key intermediates in many reactions, paving the way for the construction of complex organic molecules. The existence of methyl groups also affects the spatial configuration and polarity of compounds.
"2-fluoro-1-iodine-3-methylbenzene" has potential applications in drug research and development, materials science, etc. It may provide key structural units for the creation of new drugs; in material synthesis, or endow materials with unique properties. Its unique structure and properties are waiting for us to explore and make good use of.
Physical & Chemical Properties
The industry of chemical industry is very important in the research of substances. Today's substance is called "Benzene, 2 - Fluoro - 1 - Iodo - 3 - Methyl -", and its physical and chemical properties are worth studying in depth.
The physical properties of this substance, the color state may be unique, or it may be a clear liquid or a crystalline solid, and its characteristics can be seen from the perspective. Its melting and boiling point depends on the scope of application, and the high or low temperature environment determines the change of its shape. And its solubility, in various solvents, may be soluble or insoluble, which is the key.
As for chemical properties, the presence of fluorine, iodine, and methyl in its structure makes its reactivity unique. In case of electrophilic reagents, it may react with substitution to form a different product. In case of oxidation and reduction reagents, it will also exhibit unique chemical changes, which may be of extraordinary use in the field of organic synthesis. Therefore, the study of the physical and chemical properties of this substance can contribute to the progress of the chemical industry and help many industries.
Technical Specifications & Labeling
Today there is a thing called "Benzene, 2 - Fluoro - 1 - Iodo - 3 - Methyl -", which is related to the technical specifications and identification (commodity parameters) of this substance. We need to discuss it in detail.
Looking at its chemical composition, this compound has unique characteristics. In order to clarify its technical specifications, its physical properties, such as melting point and boiling point, are observed, which are related to its morphological changes under different conditions. It is also necessary to study chemical properties, such as reactivity, to know its performance in various chemical reactions.
When it comes to identification, commodity parameters are also key. From the purity identification, its purity can be determined, which affects its application field. The packaging label is related to the specifications of storage and transportation. All of this is to grasp the technical specifications and labels of this "Benzene, 2 - Fluoro - 1 - Iodo - 3 - Methyl -" substance, which must be carefully inspected.
Preparation Method
To prepare 2-fluoro-1-iodine-3-methylbenzene, the method is as follows:
First take an appropriate amount of raw materials, and use a delicate chemical process to react in several steps. The choice of starting materials is about success or failure. If you choose a suitable halogenated aromatic hydrocarbon, and a fluorine-containing and iodine reagent, put it into the reaction system in a delicate ratio.
The first step is to make the halogenated aromatic hydrocarbon and the fluorine-containing reagent react according to specific conditions, or heat, or control the temperature, with the assistance of a catalyst, so that the fluorine atom is just in the designated position of the benzene ring. This step requires careful observation of the reaction process and control of its rate and direction.
The second step is to introduce i The carefully designed reaction path allows iodine to be ingeniously combined with fluorinated benzene derivatives to obtain the prototype of the target product.
During the preparation process, it is crucial to regulate the reaction conditions, such as temperature, pressure, and reaction time, all of which need to be carefully controlled. And in order to promote the efficient progress of the reaction, a reasonable catalytic mechanism is set up to make each step of the reaction smooth and improve the purity and yield of the product. According to this process, 2-fluoro-1-iodine-3-methylbenzene can be obtained.
Chemical Reactions & Modifications
The chemical reaction and modification of a derivative of benzene, 2-fluoro-1-iodine-3-methyl, are of great importance to our research. To observe the reaction depends on changes in conditions, such as temperature and the genus of solvents. At a suitable temperature, choose an appropriate solvent, or it can promote the speed of the reaction and increase the yield.
If it is modified, other groups can be introduced to change its properties. The structure of this compound determines the direction of the reaction. The conjugation of the benzene ring, the position and properties of fluorine, iodine and methyl all affect the reaction. The electronegativity of fluorine can lead to the transfer of electron clouds and change the activity of benzene rings; although iodine is large, it also has its site effect; methyl adds electron supply to make the reaction different.
We should study various factors, seek the best reaction, good modification, and hope to obtain better performance and use of this compound, and contribute to chemistry.
Synonyms & Product Names
"About Synonyms and Trade Names of" Benzene, 2 - Fluoro - 1 - Iodo - 3 - Methyl - "
There is a product named" Benzene, 2 - Fluoro - 1 - Iodo - 3 - Methyl - ". In the field of chemical industry, it is common to have more than one product. This substance also has many synonyms, or according to its structural characteristics, or according to traditional appellations, different names are derived.
The trade name is related to the marketing and market identification of merchants. In order to make their products stand out, merchants often give them unique trade names. Although synonyms and trade names are different, they all refer to this specific "Benzene, 2 - Fluoro - 1 - Iodo - 3 - Methyl -" substance. When researching and applying, it is easy to identify its synonyms and trade names without the risk of misuse, and help the chemical industry move forward smoothly.
Safety & Operational Standards
"2-Fluoro-1-iodine-3-methylbenzene" product safety and operating specifications
Husband "2-fluoro-1-iodine-3-methylbenzene" is an important substance for chemical research. Its safety and operating standards are related to the safety of the experimenter and endanger the smooth progress of the research, which cannot be ignored.
For storage, it must be placed in a cool and ventilated warehouse. Keep away from fire and heat sources to prevent accidents. It should be stored separately from oxidants, acids, bases, etc., and should not be mixed to avoid the disaster of chemical reactions. The storage area must be prepared with suitable materials to contain leaks, just in case.
When operating, the experimenter should strictly follow the norms. Be sure to wear a self-priming filter gas mask (full mask), tape gas suit, rubber gloves, and fully armed to prevent damage. The operating environment needs to be well ventilated to expel harmful gases. Avoid contact with skin and eyes. If you are in careless contact, rinse with a lot of water immediately and seek medical attention in time.
When taking it, the action should be slow to prevent spillage. Measure accurately, not more or less, to meet the needs of the experiment. After use, properly clean the utensils and do not leave any residue.
In case of leakage, evacuate the personnel and stay away from the scene. Emergency responders must wear protective equipment before entering. Small leaks are absorbed by inert materials such as sand and vermiculite. If there are large leaks, build a dike or dig a pit to contain them, transfer them to a tanker or special collector with a pump, and recycle or transport them to a waste treatment site for disposal.
In short, in the research of "2-fluoro-1-iodine-3-methylbenzene", safety and standards are as indispensable as the wings of a bird and the two wheels of a car. Only by strictly observing it can we ensure the safety of research and promote fruitful results.
Application Area
Today there is a thing called "Benzene, 2 - Fluoro - 1 - Iodo - 3 - Methyl -", which is used in various fields. In the field of medicine, it may help to develop new agents to treat various diseases. Because of its unique structure, it may interact with specific targets in the body to achieve the effect of curing and saving people. In the chemical industry, it can also be used as raw materials to make other useful substances. Or it can be converted into materials with unique properties through exquisite methods for the manufacture of equipment and appliances. It is even more important for scientific research and exploration. Helping students gain insight into the wonders of material changes and develop new territories of cognition. From this point of view, this object has extraordinary value in many application fields such as medicine, chemical industry, scientific research, etc., and it cannot be ignored.
Research & Development
I have been engaged in the research of chemicals for a long time. Recently in "Benzene, 2 - Fluoro - 1 - Iodo - 3 - Methyl -" this compound has a lot of effort.
Preliminary study of its structure, this is an organic compound, and the substitution positions of fluorine, iodine and methyl have a great impact on its chemical properties. After repeated experiments, the reaction between it and various reagents was observed. Using a specific catalyst to observe its participation in nucleophilic substitution reactions, the results were remarkable, and the product purity was quite good.
However, the road to research and development was not smooth, and the control of reaction conditions was the key. The yield and purity of the product were affected when the temperature and pressure were slightly different. In order to optimize, study day and night, adjust the parameters, and finally obtain a better reaction plan.
Wuxin, continue to make progress, and the research on "Benzene, 2 - Fluoro - 1 - Iodo - 3 - Methyl -" compounds will definitely be able to go to a higher level, contributing to the development of the chemical field.
Toxicity Research
The judgment of material properties is related to the safety of people's livelihood. Today there is a thing called "Benzene, 2 - Fluoro - 1 - Iodo - 3 - Methyl -", and the investigation of its toxicity is an important matter.
In this matter, it is also necessary to investigate its properties carefully. According to ancient books, the poison of chemicals may hurt the organs, or damage qi and blood. This "Benzene, 2 - Fluoro - 1 - Iodo - 3 - Methyl -" has a unique molecular structure, and fluorine, iodine, methyl and benzene are related. Fluoride is strong in nature, or disturbs the order of biochemistry in the body; although iodine is needed by the human body, it is combined with other atoms in this substance, and it is unknown what its harm is; methyl is also not a good kind, or it is often chaotic cells.
To understand its toxicity, you should follow the scientific method. Take animals as an experience, observe their diet, action, and physiological changes; analyze their metabolism, and know what they belong to in the body. And it is time to observe their volatilization and water solubility, so as to prevent them from escaping into the environment and harming all living beings. The study of toxicity should not be ignored, but must be cautious and careful, so as to ensure the well-being of all people and the tranquility of the environment.
Future Prospects
I have tried to research the technology of chemical industry, and I am particularly concerned about 2-fluoro-1-iodine-3-methylbenzene. Its characteristics are unique and its uses are quite wide, and it can be used in various fields of medicine and materials.
Looking at the current situation, although the synthesis method is slightly successful, there is still a long way to go to achieve refinement. The synthesis rate is not perfect, and the control of impurities also needs to be refined.
As for the future outlook, my heart hopes that it will create an efficient method, so that the yield can leap and impurities can be eliminated. If so, in the creation of medicine, it can help new drugs to be released quickly and cure more diseases; in the research and development of materials, it can create novel materials and promote the progress of science and technology. May over time, get what you want, and contribute to the prosperity of chemical industry, so that this substance can bloom brightly and benefit the world.
Where to Buy Benzene, 2-Fluoro-1-Iodo-3-Methyl- in China?
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Frequently Asked Questions

As a leading Benzene, 2-Fluoro-1-Iodo-3-Methyl- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

Benzene, what are the chemical properties of 2-Fluoro-1-Iodo-3-Methyl-?
2-Fluoro-1-iodine-3-methylbenzene, this is an organic compound. Looking at its structure, there are fluorine atoms, iodine atoms and methyl groups attached to the benzene ring. Its chemical properties are unique, due to the conjugation system of the benzene ring and the interaction of electronic effects of each substituent.
Fluorine atoms have strong electronegativity, which will reduce the electron cloud density of the benzene ring and weaken the activity of the electrophilic substitution reaction of the benzene ring. However, it can cause the density of the adjacent and para-position electron clouds to increase relatively. Therefore, during the electrophilic substitution reaction, the new substituent tends to enter the ortho and para-position. Although the iodine atom has high electronegativity, its atomic radius is large, and the conjugation effect with the benzene ring is weak The electron cloud density of the benzene ring can be increased by methyl as the power supply group, which enhances the electrophilic substitution activity of the benzene ring, and mainly causes new substituents to enter ortho and para-sites.
In the electrophilic substitution reaction, the reactivity and selectivity of the compound show a complex situation due to the synergistic effect of the substituents. For example, in the halogenation reaction, the electrophilic reagents such as chlorine or bromine attack the benzene ring, and the reaction conditions may be more severe than that of benzene, and the substitution position will be comprehensively dominated by the directing effect of each substituent. Under some specific reaction conditions, fluorine and iodine atoms may participate in the nucleophilic substitution reaction, but such reactions require specific reagents and conditions
In addition, the compound may exhibit unique properties in oxidation, reduction and other reactions, due to the influence of each substituent on the electronic structure of the benzene ring, which in turn affects its overall chemical activity. The chemical properties of this compound are complex and changeable due to the interaction of each substituent, and may have potential applications in organic synthesis and other fields.
Benzene, what are the physical properties of 2-Fluoro-1-Iodo-3-Methyl-?
The author of "Tiangong Kaiwu" is also a strange book of ancient science and technology. However, it is difficult to describe the physical properties of "2-fluoro-1-iodine-3-methylbenzene" in detail according to ancient words. This is a chemical substance of today, not existing in ancient times. This is described in the style of ancient times.
"2-fluoro-1-iodine-3-methylbenzene", at room temperature, or in a liquid state. Its color may be nearly colorless, and it has a special smell. However, the ancient books can accurately state that this smell is not ancient, because it was not heard at that time. Its density is different from that of water, or slightly heavier, and it sinks under water.
The boiling point of this substance is also its important physical property. According to today's scientific calculations, it can reach a certain temperature, and then liquefy into gas and rise away. As for the melting point, at a specific low temperature, it will change from liquid to solid, and the shape will change according to the temperature.
Furthermore, its solubility also has characteristics. In water, it may be difficult to dissolve, but organic solvents, such as ethanol, ether, etc., may have good solubility and can be mixed with it. This is due to the characteristics of the molecular structure. The force between its molecules determines its many physical properties. Although it is difficult to describe it in detail and accurately in ancient words, it is now possible to gain clear insights through scientific methods, so that future generations can understand its characteristics and use it in various ways, such as chemical industry, medicine, etc., to benefit people.
Benzene, what is the main use of 2-Fluoro-1-Iodo-3-Methyl-?
2-Fluoro-1-iodine-3-methylbenzene is also an organic compound. It has a wide range of uses and is useful in various fields.
In the field of medicinal chemistry, this compound can be a key intermediate. Due to its unique chemical structure, the presence of fluorine, iodine and methyl gives it special chemical activities and physical properties. Chemists can chemically modify it to build more complex structures, and then develop new drugs with specific pharmacological activities. If it is used as a starting material, through a series of reactions, it may be able to produce compounds with therapeutic effects on specific diseases, such as anti-tumor, anti-viral drugs.
In the field of materials science, 2-fluoro-1-iodine-3-methylbenzene also has important functions. It can participate in the synthesis of polymer materials with special properties. The introduction of fluorine atoms may improve the chemical resistance and thermal stability of materials; iodine atoms may affect the electrical properties of materials, and methyl groups also play a role in the solubility and crystallinity of materials. The materials synthesized from this may be used in electronic devices, optical materials and other fields, such as the preparation of high-performance organic semiconductor materials for organic Light Emitting Diodes (OLEDs), organic field effect transistors (OFETs) and other devices to improve their performance.
In organic synthesis chemistry, this compound is often an important building block. Its diverse reaction check points can participate in many organic reactions, such as nucleophilic substitution reactions, coupling reactions, etc. Chemists can use this to construct carbon-carbon bonds, carbon-heteroatom bonds, expand the skeleton of molecules, and synthesize organic compounds with different structures, providing rich means and material basis for the development of organic synthetic chemistry.
In summary, 2-fluoro-1-iodine-3-methylbenzene plays an important role in many fields such as medicine, materials, and organic synthesis, and is of great significance to promote scientific research and technological development in related fields.
Benzene, what is 2-Fluoro-1-Iodo-3-Methyl- synthesis?
The preparation of 2-fluoro-1-iodine-3-methylbenzene can be done according to the following ancient method.
Starting material, select 3-methylaniline, and first make it diazotized with hydrochloric acid and sodium nitrite at low temperature. This process requires careful temperature control and maintenance of a low temperature environment to convert 3-methylaniline into diazonium salts. The reason is that the diazotization reaction conditions are harsh, and the diazonium salt is easy to decompose at a slightly higher temperature, causing the reaction to fail.
The diazonium salt generated reacts with fluoroborate acid to obtain fluoroborate precipitation. After the precipitation is separated, dried, and then decomposed by heating, 3-methylfluorobenzene is obtained. In this step, the separation and drying operations must be fine to remove impurities and ensure the purity of the product; the temperature of heating decomposition also needs to be precisely controlled, so that the fluoroborate can be smoothly converted into 3-methyl fluorobenzene.
Then, the iodization reaction is applied to 3-methyl fluorobenzene. The iodine elemental substance can be reacted with an appropriate oxidant, such as hydrogen peroxide, in a suitable solvent. This is because the activity of the iodine elemental substance is slightly weak, and the oxidant needs to be assisted before the substitution reaction with the benzene ring can occur. During the reaction, the choice of solvent is very critical, and it is necessary to ensure that the reactants are well dissolved and do not interfere with the reaction process.
After the reaction is completed, regular separation and purification methods, such as distillation, extraction, column chromatography, etc., remove by-products and unreacted raw materials, and finally obtain pure 2-fluoro-1-iodine-3-methylbenzene. Between each step, the material transfer and the control of the reaction conditions must not be lost, so that the preparation can be smooth and the target product can be obtained.
Benzene, 2-Fluoro-1-Iodo-3-Methyl- what are the precautions during storage and transportation
When storing and transporting 2-fluoro-1-iodine-3-methylbenzene, pay attention to many things.
First of all, pay attention to its chemical properties. 2-fluoro-1-iodine-3-methylbenzene contains halogen atoms such as fluorine and iodine, and has methyl groups, which have different chemical activities. Because of its halogenated aromatic hydrocarbon properties, it encounters specific reagents, or reacts such as substitution and addition. When storing, choose a dry, cool and well-ventilated place, avoid direct sunlight, and cause deterioration under its light or promote reactions.
Times and packaging must be tight. Due to its volatility and irritation, if the packaging is not good, the escaping gas will pollute the environment and endanger the human body. It is commonly used in glass or specific plastic containers, but it is necessary to consider its compatibility with the material, such as glass or biochemical reaction with it, that is, it is necessary to choose a suitable substitute.
During transportation, shock protection is also a priority. Bumping vibration or causing damage to the container, causing material leakage. It must be lined with soft materials and placed firmly. And the transport vehicle should be equipped with fire extinguishing and leakage emergency treatment equipment in case of accidents.
Furthermore, personnel protection is indispensable. Those who come into contact with this object, wear protective clothing, protective gloves and goggles, because it may irritate the skin, eyes and respiratory tract. In case of accidental contact, rinse with plenty of water immediately and seek medical attention.
In addition, storage and transportation sites must be clearly marked to indicate their dangerous characteristics and let relevant personnel know the risks. And regulations on chemical storage and transportation should be strictly followed to ensure that the process is standardized and safe. In this way, 2-fluoro-1-iodine-3-methylbenzene is safe during storage and transportation.