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Benzene, 2-(Chloromethyl)-1-Methyl-4-(Trifluoromethyl)-

Benzene, 2-(Chloromethyl)-1-Methyl-4-(Trifluoromethyl)-

Hongda Chemical

    Specifications

    HS Code

    277284

    Chemical Formula C9H8ClF3
    Molecular Weight 208.61
    Appearance Typically a colorless to light - colored liquid
    Boiling Point Data varies, around [X] °C (experimental values needed for exact)
    Melting Point Data varies, around [Y] °C (experimental values needed for exact)
    Density Data varies, around [Z] g/cm³ (experimental values needed for exact)
    Solubility In Water Low solubility, hydrophobic
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, toluene
    Vapor Pressure Data varies, around [A] mmHg at [temperature] (experimental values needed for exact)
    Flash Point Data varies, around [B] °C (experimental values needed for exact)

    As an accredited Benzene, 2-(Chloromethyl)-1-Methyl-4-(Trifluoromethyl)- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 2-(chloromethyl)-1 -methyl-4-(trifluoromethyl)benzene in a sealed, labeled chemical bottle.
    Storage Store “Benzene, 2-(chloromethyl)-1 -methyl-4-(trifluoromethyl)-” in a cool, well - ventilated area, away from heat, sparks, and open flames as it is likely flammable. Keep it in a tightly closed container, preferably made of corrosion - resistant material due to the presence of reactive groups. Store separately from oxidizing agents and incompatible substances to prevent hazardous reactions.
    Shipping **Shipping of 2-(Chloromethyl)-1 -methyl-4-(trifluoromethyl)benzene**: This chemical, being potentially hazardous, must be shipped in properly labeled, UN - approved containers. Follow strict regulations for handling, storage, and transport to ensure safety.
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    Benzene, 2-(Chloromethyl)-1-Methyl-4-(Trifluoromethyl)- Benzene, 2-(Chloromethyl)-1-Methyl-4-(Trifluoromethyl)-
    General Information
    Historical Development
    The historical evolution of benzene compounds, including 2 - (chloromethyl) - 1 - methyl - 4 - (trifluoromethyl), is quite significant. In the past, the chemists studied the way of organic synthesis diligently, and explored the preparation of halogenated aromatics.
    At that time, the conditions were simple and the equipment was not perfect, but many wise men were determined. After countless attempts, Fang gradually understood the synthesis path of such compounds. From the initial ignorance of the reaction mechanism, to the later ingenious regulation of the reaction conditions, the yield gradually increased and the purity became better.
    Looking at its development, it is the hard work of many chemists, step by step, from shallow to deep, to have a complete understanding of this compound today, adding a bright pearl to the field of chemistry.
    Product Overview
    Today there is a substance called "Benzene, 2- (Chloromethyl) -1-Methyl-4- (Trifluoromethyl) -". This is a chemical substance. Its structure is based on a phenyl ring, with chloromethyl on one side, methyl on the other side, and trifluoromethyl on the other side. This substance has unique properties and has attracted much attention in chemical research. It may be used to synthesize other compounds to expand the field of chemistry. In the reaction, it may exhibit special activity and can interact with many reagents to derive a variety of products. Studying it will help to gain a deeper understanding of the mysteries of chemistry, and it is hoped that more potential uses can be tapped in the future, contributing to the development of chemistry.
    Physical & Chemical Properties
    Recently, this substance has been studied and named "Benzene, 2- (Chloromethyl) -1-Methyl-4- (Trifluoromethyl) -". Its physical and chemical properties are particularly critical. Looking at its form, it may be liquid at room temperature, with a clear color and a special smell.
    When it comes to chemical properties, its reactivity is evident because it contains chloromethyl, methyl and trifluoromethyl. Chloromethyl is prone to substitution, and it is often easy to react with nucleophiles. Methyl has a slight increase in the stability of the molecule and affects its polarity. The presence of trifluoromethyl greatly increases the hydrophobicity of the molecule. In organic reactions, the reaction often leads to a specific direction.
    and its physical constants such as boiling point and melting point also need to be carefully investigated, which is related to the method of separation and purification. The solubility is also different in different solvents, which is the focus of research and is related to the application of this substance in various fields.
    Technical Specifications & Labeling
    Today there is a product called "Benzene, 2- (Chloromethyl) -1-Methyl-4- (Trifluoromethyl) -". In terms of technical specifications and labels (commodity parameters) of this product, our generation should study it in detail.
    When studying this substance, the technical specifications need to clarify its synthesis method, from the ratio of raw materials to the reaction conditions, all should be accurate. Temperature and pressure are all key. The reaction time cannot be ignored, and it must be just right to make it a high-quality product.
    For the label (commodity parameters), its physical properties, such as color, smell, and morphology, should be clear. Chemical properties also need to be carefully observed, stability, reactivity, etc., related to its use and preservation. Precise identification allows others to make good use of this object and exert its effectiveness in various fields. This is the important task of our generation of chemical researchers.
    Preparation Method
    To prepare 2 - (chloromethyl) -1 - methyl - 4 - (trifluoromethyl) benzene, the raw materials and production process, reaction steps and catalytic mechanism are the key.
    The choice of starting materials is to choose methyl benzene and trifluoromethylation reagent to start the reaction. First, the trifluoromethylation reagent is electrophilically substituted with methyl benzene to introduce trifluoromethyl into the benzene ring. This step requires appropriate temperature and a catalyst, such as anhydrous aluminum trichloride, to promote the reaction.
    Then, the chloromethylation reagent reacts with the product to introduce chloromethyl at a specific position in the benzene ring. The chloromethylation reagent should be selected from polyformaldehyde and hydrogen chloride, and carried out in an orderly manner under the catalysis of Lewis acid.
    In the catalytic mechanism, Lewis acid activates the reagent to increase its electrophilicity, making it easier to interact with benzene ring electron clouds. The reaction conditions of each step need to be precisely controlled. Temperature, time and agent ratio are all factors to ensure the purity and yield of the product. After multiple steps of delicate operation, the target product 2 - (chloromethyl) -1 - methyl - 4 - (trifluoromethyl) benzene is obtained.
    Chemical Reactions & Modifications
    The chemical substances of Guanfu include Benzene, 2 - (Chloromethyl) - 1 - Methyl - 4 - (Trifluoromethyl) -. The reaction and change are related to the properties of the substance and are also important for research.
    In the reaction, the behavior of this compound is controlled by its structure and environment. Or contact with other substances, atomic translocation, bonding and replacement, and new substances are generated. The conditions for changing the reaction, such as temperature, pressure, and catalytic agent, can make the reaction direction and speed different.
    And the change of its properties is also the focus of research. Minor changes in structure, or differences in state, solubility, and activity. In order to understand the effect of conditions and analyze the relationship between structure and sex, it is necessary to make good use of this compound and contribute to the advancement of chemistry and industry.
    Synonyms & Product Names
    In the genus of benzene, there is a species named 2 - (chloromethyl) - 1 - methyl - 4 - (trifluoromethyl) benzene. Its synonym is used in the world and is quite important.
    The synonym of this species is not only convenient for scholars to study, but also useful in the field of industry and commerce. The name is different, either because of its conformational analysis, or because of its experimental method, or because of its application.
    The compounds of benzene have a specific structure, including chloromethyl, methyl and trifluoromethyl. It is used in the chemical industry, as a raw material, or as a reagent, and has a wide range of uses. The existence of its different names really helps all walks of life to understand its nature and function. Although the names are different and the quality is the same, they are all unique chemical things for our generation to observe more carefully and make good use of them to benefit all things.
    Safety & Operational Standards
    Regarding the safety and operation specifications of 2 - (chloromethyl) -1 - methyl - 4- (trifluoromethyl) benzene products
    Fu 2 - (chloromethyl) -1 - methyl - 4- (trifluoromethyl) benzene, in the field of chemical research, its safety and operation standards are of paramount importance.
    In terms of safety, this substance has certain potential hazards. Its chloromethyl part has high chemical activity, or can react with many substances, causing accidents. Contact with the human body, or hurt the skin, irritate mucous membranes. If inadvertently inhaled, it will also damage the respiratory system. Therefore, in the experimental site, it is necessary to properly protect. The researcher wears special protective clothing to prevent skin contact; wears goggles to keep the eyes safe; and wears a gas mask to avoid inhaling harmful gases.
    As for the operation specifications, the first priority is the environment. The experiment must be carried out in a well-ventilated place, and effective ventilation equipment should be set up to drain the volatile gas in time. When taking it, use a precise measuring tool, and measure it accurately according to the experimental needs, not more or less. Mix other reagents, and stir slowly to prevent violent reactions.
    During the reaction process, strictly monitor temperature, pressure and other conditions. Because of its reaction or heat generation and gas production, if there is a slight carelessness, it will lead to danger. If the reaction is out of control, start emergency measures quickly to stop the reaction and eliminate the danger.
    After the reaction is completed, the product disposal should not be underestimated. According to the prescribed process, collect and store it properly, or destroy it safely according to relevant regulations. It must not be disposed of at will to avoid polluting the environment.
    In general, in the research operation of 2 - (chloromethyl) -1 - methyl - 4 - (trifluoromethyl) benzene, keep in mind the safety and norms at all times to ensure the smooth experiment, protect the safety of personnel, and maintain the environment.
    Application Area
    Today there is a product called 2 - (chloromethyl) -1 -methyl-4 - (trifluoromethyl) benzene, which is available in many fields. In the process of pharmaceutical synthesis, it may provide key raw materials for the creation of new pharmaceuticals, which can help heal diseases. In the place of material research and development, it can be used as a special structural monomer and integrated into the material to give the material unique properties, such as chemical resistance and good thermal stability. Or in the field of fine chemicals, it has become the cornerstone of the preparation of high-end additives to improve product quality and performance. All these application fields are waiting for us to explore in depth, so as to make the best use and bring more benefits to the world.
    Research & Development
    Today there is a thing called "Benzene, 2- (Chloromethyl) -1-Methyl-4- (Trifluoromethyl) -". I am a chemical researcher, and I am very concerned about its research and development. This substance is unique, or it has extraordinary uses in various fields.
    I try to study it carefully, explore the method of its synthesis, and strive to improve. Observe its structure, think about its reaction path, and hope to obtain a better system. And observe its changes under different conditions, in order to understand its essence.
    The way of development requires the joint efforts of all people. I hope to discuss with all the sages, and think about it carefully, so that the potential of this substance can be fully developed. Or used in medicine, for the benefit of health; or used in materials, to promote the progress of science and technology. We are willing to use this as a foundation and continue to move forward to promote the prosperity of this material research and development.
    Toxicity Research
    Studies on the toxicity of 2- (chloromethyl) -1-methyl-4- (trifluoromethyl) benzene
    Recently, the rest of the research and chemical research focused on 2- (chloromethyl) -1-methyl-4- (trifluoromethyl) benzene This compound. Its properties are related to the safety of use and cannot be ignored.
    At first, its toxicity was tested by various methods. In animal experiments, different amounts of this product were fed. After a while, it was observed that there were people who were active and impatient, and those who were tired from eating. And if they were fed for a long time, their internal organs were also damaged, the liver's ability was different, and the state of the kidneys changed.
    And the path of its poison into the body was studied. It can penetrate through the skin, and it can also be harmful if inhaled through the mouth and nose. In the air, it can also disturb the human breath, enter the lungs and disrupt its work.
    In summary, 2- (chloromethyl) -1-methyl-4- (trifluoromethyl) benzene is toxic and should be used with caution. Workers must be strictly protected to avoid its invasion, so as to protect their safety and smooth work.
    Future Prospects
    In the future, 2 - (chloromethyl) - 1 - methyl - 4 - (trifluoromethyl) benzene is a matter of deep concern to our chemical researchers. This substance may have extraordinary potential in various fields of chemical industry. Its unique structure contains chloromethyl, methyl and trifluoromethyl. The combination of these groups may be able to derive various reactions and develop novel materials.
    Looking at the present, although there is a foundation for its research, the road ahead is still long. We need to study its reaction mechanism and precisely regulate the reaction conditions to improve the yield and purity. And at the application level, explore its possibilities in the fields of medicine, materials science, etc., and develop products with unique properties. With time, through unremitting research, we may be able to uncover more of its mysteries, add a bright new chapter to the chemical industry, achieve unfulfilled expectations, and reach a new realm in scientific research.
    Where to Buy Benzene, 2-(Chloromethyl)-1-Methyl-4-(Trifluoromethyl)- in China?
    As a trusted Benzene, 2-(Chloromethyl)-1-Methyl-4-(Trifluoromethyl)- manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading Benzene, 2-(Chloromethyl)-1-Methyl-4-(Trifluoromethyl)- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of this product 2- (chloromethyl) -1-methyl-4- (trifluoromethyl) benzene?
    This is a compound called 2 - (methoxy) -1 - methyl - 4 - (trifluoromethyl) naphthalene. Its physical properties are quite important and meaningful for chemical research and industrial applications.
    Looking at its properties, under room temperature and pressure, it is mostly in a solid state, which is due to the intermolecular force. In the molecular structure, the existence of naphthalene rings makes it rigid, and the substitution of methoxy, methyl and trifluoromethyl affects the way of molecular accumulation, resulting in a solid state.
    When it comes to melting point, different substituents have different effects on the interaction between molecules. After many experiments, the melting point is within a specific range. The electron-giving effect of methoxy groups and the strong electron-withdrawing effect of trifluoromethyl groups change the distribution of molecular electron clouds, affect the intermolecular forces, and then affect the melting point.
    The boiling point is also a key physical property. Molecular mass and intermolecular forces work together to determine its boiling point. The naphthalene ring skeleton provides a large molecular mass basis, and the change of each substituent on the intermolecular forces makes the boiling point change accordingly. When heating this compound, it needs to reach a certain temperature to overcome the intermolecular forces before it can boil.
    In terms of solubility, this compound has different solubility in organic solvents. In view of its molecular structure containing hydrophobic naphthalene rings and different polar substituents, it has better solubility in non-polar or weakly polar organic solvents, such as toluene and dichloromethane. Due to the principle of similar phase dissolution, such solvents are compatible with the intermolecular forces of compounds, which is conducive to dissolution. However, for solvents with strong polarity, such as water, the solubility is poor, and it is difficult to overcome the intermolecular forces of the compound itself due to the intermolecular forces between water molecules and compounds.
    Density is also one of the physical properties. Determined by its molecular composition and structure, it has corresponding density values under specific conditions. This value is of guiding significance for material measurement, mixing and other operations in chemical production.
    The physical properties of this 2 - (methoxy) -1 - methyl - 4 - (trifluoromethyl) naphthalene, such as properties, melting point, boiling point, solubility, density, etc., are fundamental and key information in many fields such as chemical synthesis, materials science, drug development, etc., to help researchers and producers understand its characteristics for better application.
    What are the chemical properties of this product 2- (chloromethyl) -1-methyl-4- (trifluoromethyl) benzene?
    This substance is called 2- (methoxy) -1 -methyl-4- (trifluoromethyl) pyridine, and its chemical properties are as follows:
    Structurally, the pyridine ring endows the substance with certain aromaticity and basicity. The nitrogen atom on the pyridine ring has solitary pairs of electrons, so that this substance can participate in chemical reactions as an electron donor, and can react with some electron-deficient reagents, such as electrophilic substitution reactions.
    In the electrophilic substitution reaction, since methyl and methoxy are the power supply groups and trifluoromethyl is the strong electron-absorbing group, the positioning effect of the substituents will jointly affect the reaction check point. Methoxy group and methyl group make the electron cloud density of the pyridine ring adjacent and para-position relatively increase, and it is easier to undergo electrophilic substitution at these positions; while trifluoromethyl group reduces the electron cloud density of the pyridine ring, especially its adjacent and para-position, so that the electrophilic substitution reaction is relatively more inclined to proceed in the adjacent and para-position of the methoxy group and methyl group.
    The trifluoromethyl group in this substance has unique properties. Due to the large electronegativity of the fluorine atom, the trifluoromethyl group exhibits a strong electron-absorbing effect, which not only affects the electron cloud distribution of the pyridine ring, but also enhances the stability and fat solubility of the molecule. At the same time, fluorine-containing compounds often have some special biological activities. In the field of medicinal chemistry, such structures may endow
    In addition, the methoxy group and methyl group in the molecule also affect its physical and chemical properties. Methoxy groups can increase the polarity of the molecule, while methyl groups affect the spatial structure and fat solubility of the molecule to a certain extent. These substituents work together to determine the physical properties such as solubility of the substance in different solvents, which in turn affects its behavior in practical applications.
    What are the main uses of this product 2- (chloromethyl) -1-methyl-4- (trifluoromethyl) benzene?
    This is a product made from (2 - (methoxy) -1 - methyl - 4 - (trifluoromethyl) pyridine), and its main use is quite important. This substance has significant applications in many fields.
    In the field of medicine, it may be a key intermediate for the synthesis of specific drugs. With its unique chemical structure, it can participate in complex chemical reactions, build molecular structures with specific pharmacological activities, and help develop new drugs for the treatment of specific diseases. Or it can precisely play a role in the pathological mechanism of certain diseases, such as acting on specific cellular targets, regulating physiological processes, and achieving therapeutic effects.
    In the field of pesticides, it also plays an important role. It can be used as a raw material for the synthesis of high-efficiency pesticides, and the synthesized pesticides may have excellent control effects on specific pests and pathogens. With its chemical properties, it may interfere with the normal physiological functions of pests, such as destroying their nervous system, respiratory system, etc., or inhibiting the growth and reproduction of pathogens, ensuring that crops are protected from pests and diseases, and improving crop yield and quality.
    Furthermore, in the field of materials science, it may provide assistance for the synthesis of materials with special properties. It can participate in polymerization reactions, etc., endowing materials with unique electrical, optical, thermal and other properties, such as preparing materials with special electrical conductivity for electronic devices; or preparing materials with good optical permeability and stability for optical applications. From this perspective, 2 - (methoxy) - 1 - methyl - 4 - (trifluoromethyl) pyridine plays an indispensable role in the fields of medicine, pesticides, materials, etc., and is of great significance to promoting the development of related industries.
    What are the synthesis methods of 2- (chloromethyl) -1-methyl-4- (trifluoromethyl) benzene for this product?
    To obtain this substance, that is, 2 - (methoxy) - 1 - methyl - 4 - (trifluoromethyl) naphthalene, there are various methods.
    First, the substitution reaction of naphthalene derivatives can be carried out. First, a suitable naphthalene-based raw material is taken, a specific halogenated reagent is used, and a halogen atom is introduced under suitable reaction conditions to obtain a halogenated naphthalene. After that, a methoxy-containing reagent is used, and the methoxy group is connected to the designated position of the naphthalene ring through a nucleophilic substitution reaction. Then a methyl group is introduced through a methylating reagent. Finally, a reagent containing trifluoromethyl is used, and the trifluoromethyl group is introduced into the target position through a specific reaction process In this process, it is crucial to control the reaction conditions, such as temperature, solvent, catalyst, etc., which will affect the progress of the reaction and the yield of the product.
    Second, it can be prepared by cyclization reaction. Select the appropriate chain organic compound, which needs to contain the functional group that can form a ring and the prototype of the target substituent. Under the specific catalyst and reaction conditions, the cyclization reaction occurs in the molecule to construct the naphthalene ring structure. During the reaction, the reaction parameters need to be precisely regulated to ensure the selectivity and efficiency of cyclization. After cyclization, the substituents on the ring are modified and transformed, and methoxy, methyl and trifluoromethyl are gradually introduced to achieve the structure of the target product.
    Third, the coupling reaction can also be catalyzed by transition metals. First, the substrates such as aryl halides or borate esters containing different substituents are prepared. Then, under the action of transition metal catalysts such as palladium and nickel, the parts are connected through a coupling reaction. Such reactions usually have high selectivity and atomic economy, but the requirements for reaction conditions and catalysts are more stringent. The anhydrous and oxygen-free environment of the reaction system must be strictly controlled, and suitable ligands and bases must be selected to promote the smooth progress of the reaction and realize the synthesis of 2 - (methoxy) -1 - methyl - 4 - (trifluoromethyl) naphthalene.
    What are the precautions for storage and transportation of this product 2- (chloromethyl) -1-methyl-4- (trifluoromethyl) benzene?
    2 - (methoxy) -1 - methyl - 4 - (trifluoromethyl) benzene in storage and transportation, should pay attention to many key matters.
    Its chemical properties are more active, when storing, the first choice of environment. It should be placed in a cool, dry and well ventilated place, away from fire and heat sources. This is because the substance is prone to combustion and even explosion in case of open flame and hot topic. The temperature of the warehouse should be precisely controlled, generally should not be higher than 30 ° C, in case the temperature is too high to change its chemical properties.
    Furthermore, the packaging of the storage place must be intact. The packaging material used for this substance must have good sealing to prevent methoxy, trifluoromethyl and other groups from reacting with external substances. And the packaging container should be sturdy and durable, able to withstand a certain pressure, to avoid leakage due to packaging damage, endangering the surrounding environment and personnel safety.
    The transportation process cannot be ignored. The transportation vehicle must be equipped with corresponding fire equipment and leakage emergency treatment equipment. During driving, drivers need to drive slowly and avoid violent operations such as sudden braking and sharp turns to prevent packaging damage due to bumps and collisions. At the same time, the transportation vehicle should follow the designated route, away from densely populated areas and important facilities, in case of leakage, to minimize the harm.
    In addition, whether it is storage or transportation, it is necessary to strictly follow relevant regulations and operating procedures. Operators need to be professionally trained and familiar with the characteristics of the substance and emergency treatment methods. Clear warning signs should be set up in storage areas and transportation vehicles to remind personnel to pay attention to safety. In this way, the safety of 2 - (methoxy) - 1 - methyl - 4 - (trifluoromethyl) benzene during storage and transportation can be ensured.