As a leading Benzene, 2-Bromo-1-Chloro-3-Fluoro- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical name of this compound (Benzene, 2 - Bromo - 1 - Chloro - 3 - Fluoro -)
This compound is called 2-bromo-1-chloro-3-fluorobenzene. In the style of the ancient saying of Tiangong Kaiwu, it can be explained as follows: "Today there is a compound based on benzene. Above the benzene ring, there are different positions. The two positions are added with bromine atoms, one is chlorine atoms, and the three are attached with fluorine atoms, so the full name is 2-bromo-1-chloro-3-fluorobenzene. Benzene, the basic structure of organic, is cyclic and hexagonal, and is connected to carbon and carbon. Bromine, one of the halogen groups, is red-brown and volatile. Chlorine, also halogen group, is yellow-green and active. Fluorine, the first of the halogen group, is particularly strong. This compound combines the structure of benzene with the characteristics of bromine, chlorine, and fluorine, and is important in the fields of organic synthesis and chemical research. It may be involved in the exploration of reaction mechanisms, or it may be the basis for the creation of new materials. It is important for the chemical industry. "
What are its physical properties (Benzene, 2 - Bromo - 1 - Chloro - 3 - Fluoro -)
2-Bromo-1-chloro-3-fluorobenzene (Benzene, 2-Bromo-1-Chloro-3-Fluoro -) has many physical properties. Its appearance is usually colorless to light yellow liquid, which can emit a specific odor at room temperature and pressure. In terms of density, compared to water, it has a certain value. Due to the characteristics of the substance, it will exhibit a different density relationship with water. If the density is greater than water, it will sink in the water, and vice versa.
The melting point of this substance is also a key physical property. The melting point refers to the temperature at which a substance changes from a solid state to a liquid state, and the boiling point is the temperature at which it changes from a liquid state to a gas state. These values are specific and play a decisive role in their morphological changes under different temperature environments. For example, in an environment below the melting point, it exists in solid form; when the temperature is between the melting point and the boiling point, it presents a liquid state; and once the temperature is above the boiling point, it turns into a gaseous state.
The solubility is also not negligible, and its solubility in different solvents varies. In organic solvents, such as common ethanol, ether, etc., it may have good solubility, which is due to the principle of intermolecular forces. It is similar to miscibility, and its molecular structure is compatible with the organic solvent molecules, so it can be mixed with each other. However, in water, due to differences in molecular polarity, the solubility may be poor. In addition, the substance also has a certain degree of volatility, at room temperature, some molecules will break free from the liquid surface and enter the air, and its vapor pressure also has a specific value, which is closely related to the temperature. As the temperature increases, the vapor pressure increases, which has an important impact on its state and safety in storage and use environments.
What are its main uses (Benzene, 2 - Bromo - 1 - Chloro - 3 - Fluoro -)
This is about the main use of "2-Bromo-1-chloro-3-fluorobenzene (Benzene, 2-Bromo-1-Chloro-3-Fluoro-) ". 2-Bromo-1-chloro-3-fluorobenzene is a key raw material in the field of organic synthesis.
In the field of medicinal chemistry, it can be used as an intermediate to help create novel drug molecules. Due to its unique chemical structure, it can impart specific biological activity and pharmacological properties to drugs. Through a specific chemical reaction, it is combined with other functional groups to construct drugs with complex structures and curative effects.
It also has important uses in materials science. It can participate in the synthesis of materials with special properties, such as optoelectronic materials. With its structure containing halogen atoms, it may affect the electronic transmission properties and optical properties of materials, contributing to the research and development of new optoelectronic materials.
In addition, in the field of fine chemicals, it is often used as a starting material to prepare various fine chemicals. Due to the particularity of its structure, it can be derived from many products with high added value to meet the special needs of different industries. The multi-faceted uses of this compound promote scientific research and industrial production in many fields.
What are the methods for synthesizing this compound (Benzene, 2 - Bromo - 1 - Chloro - 3 - Fluoro -)
The methods for synthesizing the compound (2-bromo-1-chloro-3-fluorobenzene) can be as follows.
First, benzene is used as the starting material, and fluorine atoms are first introduced. An electrophilic substitution reaction can be used, and a suitable fluorinated reagent, such as a fluorinated Lewis acid complex, can be selected. Under specific conditions, benzene is fluorinated to obtain fluorobenzene. Then, fluorobenzene is brominated. In a suitable reaction system, such as in the presence of a catalyst (such as iron or its halide), bromine is used as a brominating reagent to undergo electrophilic substitution, and bromine atoms are introduced at suitable positions in the benzene ring to obtain 3-fluoro-1-bromobenzene. Finally, chlorination of 3-fluoro-1-bromobenzene is carried out, and similar electrophilic substitution reaction conditions are also used. Chlorination reagents (such as chlorine gas under the action of a catalyst) are used to introduce chlorine atoms at suitable positions in the remaining benzene ring to obtain the target compound 2-bromo-1-chloro-3-fluorobenzene.
Second, benzene can also be brominated first to obtain bromobenzene. Then under suitable conditions, chlorination reagents are selected to carry out chlorination reaction to obtain 1-bromo-3-chlorobenzene. Finally, fluorination reaction is carried out on 1-bromo-3-chlorobenzene, suitable fluorination reagents and conditions are selected, fluorine atoms are introduced, and then 2-bromo-1-chloro-3-fluorobenzene is synthesized.
Third, benzene can be chlorinated first to obtain chlorobenzene. Then bromine chlorobenzene to obtain 1-chloro-3-bromobenzene. Finally, the target product is synthesized by introducing fluorine atoms through a suitable fluorine substitution method. During the specific operation of each method, attention should be paid to the control of reaction conditions, such as temperature, catalyst selection and dosage, reaction solvent, etc., in order to improve the reaction yield and selectivity, and achieve the purpose of successful synthesis of the compound.
What are the risks of this compound (Benzene, 2 - Bromo - 1 - Chloro - 3 - Fluoro -)
This chemical (2-bromo-1-chloro-3-fluorobenzene) is an organohalogenated aromatic hydrocarbon. It has multiple potential hazards.
In terms of toxicity, halogenated aromatics are often toxic. Bromine, chlorine, and fluorine atoms in this compound may affect human health. Contact or ingestion through the respiratory tract, skin, or damage human organs. Such as halogenated aromatics or damage the liver and kidneys, interfering with normal metabolic processes in the body. And some halogenated aromatics may be neurotoxic, affecting the function of the nervous system, causing headaches, vertigo, fatigue, etc.
In terms of environmental hazards, they are difficult to degrade in the environment and can persist for a long time. Entering environmental media such as water bodies and soils, or enriching through the food chain. Toxic to aquatic organisms and soil microorganisms, destroying ecological balance. And it may evaporate into the atmosphere, participate in photochemical reactions, affect air quality, or generate harmful secondary pollutants.
In terms of flammability, although it is not a typical flammable substance, it may encounter hot topics, open flames, or due to the structure of benzene ring and the characteristics of halogen atoms, there is a risk of combustion and explosion. Heating or decomposition releases halogen-containing harmful gases, exacerbating the harm.
Therefore, when producing, using, and storing this compound, strict safety protection measures must be taken to prevent harm to human body and the environment.