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Benzene, 1-Methyl-4-Nitro-2-(Trifluoromethyl)-

Benzene, 1-Methyl-4-Nitro-2-(Trifluoromethyl)-

Hongda Chemical

Specifications

HS Code

517084

Chemical Formula C8H6F3NO2
Molar Mass 205.13 g/mol
Appearance Solid (Typically)
Odor May have a characteristic odor
Melting Point Data needed
Boiling Point Data needed
Density Data needed
Solubility In Water Low solubility (Expected, being an organic nitro - trifluoromethyl compound)
Vapor Pressure Data needed
Flash Point Data needed
Logp Octanol Water Partition Coefficient Data needed
Pka Data needed
Packing & Storage
Packing 500g of 1 - methyl - 4 - nitro - 2 - (trifluoromethyl)benzene in a sealed chemical - grade bottle.
Storage **Storage of 1 - methyl - 4 - nitro - 2 - (trifluoromethyl)benzene**: Store this chemical in a cool, well - ventilated area, away from heat sources and ignition points due to its potential flammability. Keep it in a tightly sealed container to prevent vapors from escaping. As it may be toxic, store it separately from foodstuffs and incompatible substances, and ensure proper labeling for easy identification and safety.
Shipping 1 - methyl - 4 - nitro - 2 - (trifluoromethyl) benzene is a hazardous chemical. Shipping requires proper classification, use of approved containers, compliance with regulations, and clear labeling for safe transportation.
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Benzene, 1-Methyl-4-Nitro-2-(Trifluoromethyl)- Benzene, 1-Methyl-4-Nitro-2-(Trifluoromethyl)-
General Information
Historical Development
In the long years of Huaxia, the exploration of chemical substances has also undergone many changes. In this case, Benzene, 1 - Methyl - 4 - Nitro - 2 - (Trifluoromethyl) - this compound, its birth and development, there are indeed traces to follow.
In the past, the chemical skills were not as exquisite as they are today, and the understanding of such complex compounds was still shallow. However, the Fangs of successive dynasties made unremitting research, from the beginning to the gradual clarification of its structural characteristics. First to identify its elemental composition, and then to explore its reaction mechanism. After countless tests, thinking and summarization, the mystery of this compound was gradually revealed. The development process of this compound is like a long journey, each step is condensed with the hearts and blood of the ancestors, laying the foundation for future chemical research, and also promoting the continuous progress of chemistry towards a more profound level.
Product Overview
Product Overview
There is currently a product named "1-methyl-4-nitro-2 - (trifluoromethyl) benzene". It is a colorless to light yellow liquid with a special odor. This substance has a wide range of uses in the chemical industry and is often used as a key intermediate in organic synthesis.
From the perspective of chemical properties, its molecular structure contains methyl, nitro and trifluoromethyl, giving it unique chemical activity. The presence of nitro groups changes the electron cloud density of the benzene ring and enhances the activity of electrophilic substitution; trifluoromethyl has strong electron absorption, which affects molecular polarity and stability.
The production of this product involves multiple chemical reactions. The selection of raw materials and the control of reaction conditions are the key. However, this material poses certain toxicity and environmental risks, and it must be used and disposed of in accordance with strict safety regulations and environmental protection requirements to ensure the safety of personnel and the environment.
Physical & Chemical Properties
1-Methyl-4-nitro-2- (trifluoromethyl) benzene is also an organic compound. Its physical and chemical properties are worth studying.
Looking at its physical properties, it is a colorless to light yellow liquid under normal conditions, with a special odor. Its boiling point and melting point depend on the characteristics of the molecular structure. The boiling point is related to the intermolecular force and the difficulty of volatilization; the melting point indicates the critical temperature for the transformation of solid and liquid states of a substance.
In terms of its chemical properties, it has unique reactivity due to the existence of benzene ring and nitro and trifluoromethyl groups. Nitro has strong electron absorption, which reduces the electron cloud density of the benzene ring and changes the activity of electrophilic substitution. The introduction of trifluoromethyl enhances the stability and fat solubility of the compound. In the field of organic synthesis, this compound can be used as a key intermediate to participate in many reactions, such as nucleophilic substitution, reduction, etc., providing a possible way for the creation of novel functional materials and drugs.
Technical Specifications & Labeling
"On the technical specification and identification (product parameters) of 1-methyl-4-nitro-2 - (trifluoromethyl) benzene"
Fu 1-methyl-4-nitro-2 - (trifluoromethyl) benzene is an important product of the chemical industry. Its technical specifications are related to the preparation method. The raw materials must be pure, the proportion should be appropriate, and the temperature, pressure and time of the reaction are all fixed. If it is prepared by a certain method, the feeding sequence is orderly, and the stirring rate is moderate, the quality can be obtained.
As for the identification, the product parameters should be detailed. Its color, taste and state should be accurate and correct. The standard of purity is related to the quality, and the impurity content must be clearly observed and strictly controlled. And the packaging label also needs compliance, product name, content, warnings, etc., are indispensable, so that the user can understand its nature and know its risks, so as to ensure safety and promote application.
Preparation Method
In order to prepare 1-methyl-4-nitro-2 - (trifluoromethyl) benzene, the preparation method should be investigated in detail. The selection of raw materials is the key, and toluene can be used as the starting material, supplemented by fluorine-containing reagents, nitrifying reagents, etc.
Preparation process is as follows: First, toluene and fluorine-containing reagents are introduced through a substitution reaction in an appropriate ratio, at a suitable temperature and under the action of a catalyst. Then, nitrifying reagents are used. After nitrification, nitro groups are introduced at specific positions. The reaction steps are strictly controlled, and the temperature, time and reagent dosage need to be accurately measured.
In order to ensure the high efficiency of the reaction and the purity of the product, a reasonable catalytic mechanism needs to be constructed. A specific catalyst can be selected to speed up the reaction rate and improve the selectivity of the product. After each step of the reaction, it should be properly separated and purified to remove impurities and obtain high-purity 1-methyl-4-nitro-2 - (trifluoromethyl) benzene. In this way, a good method for preparing this substance can be obtained.
Chemical Reactions & Modifications
"Benzene, 1 - Methyl - 4 - Nitro - 2 - (Trifluoromethyl) -" is a chemical compound. Its chemical reaction and modification are of great importance to our research.
Look at the reaction of this compound, and it may change wonderfully under specific conditions. To obtain a good modification, it is necessary to study the elements of the reaction, such as temperature and the genus of catalysts. Temperature is slightly different, the rate of the reaction and the properties of the product are changed.
The catalyst is also critical, and the appropriate catalyst can promote the reaction to go faster and make the product have better performance. We are dedicated to our research and strive to find the optimal reaction path, so that this compound can be modified to have excellent applications in various fields, contributing to the progress of chemistry.
Synonyms & Product Names
Benzene, 1 - Methyl - 4 - Nitro - 2 - (Trifluoromethyl) - This chemical substance, its alias and trade name, are quite important in our chemical research.
Viewing this substance, its structure is unique, and its properties can also be investigated. Aliases are commonly used in academic or daily research, for simple or historical reasons. Trade names are related to their circulation and application in the market.
In the course of our investigation, we know its alias or have been named according to its structural characteristics to help researchers easily call it. And trade names often consider marketing activities, uses and other factors.
Today's detailed study of Benzene, 1 - Methyl - 4 - Nitro - 2 - (Trifluoromethyl) -, to clarify its alias and trade name, can be used in practical research and production applications, accurate and accurate, without confusion, and then promote the development of the chemical field. It is also of great help to many related industries.
Safety & Operational Standards
1-Methyl-4-nitro-2 - (trifluoromethyl) benzene safety and operating specifications
1-methyl-4-nitro-2 - (trifluoromethyl) benzene, this material is strong in nature, and it is related to safety. The rules of handling should not be careless.
Its flammable nature, the ignition point is quite low, in case of open fire, hot topic, instant explosion, the tongue of fire rages, and the destruction hurts people. Therefore, where it exists, it is far away from fire and heat sources, fireworks are strictly prohibited, and fire protection is complete.
It is also toxic and harmful to the body. Oral, inhalation or skin contact can be a disaster. Damage to respiratory and nervous systems, and even life-threatening. When operating, be well protected, wear protective clothing, protective gloves, and a gas mask on your face to ensure safety.
Ventilation is crucial. In a confined space, its gas accumulates, the concentration gradually increases, and the risk increases sharply. Therefore, where the operation is carried out, the ventilation is smooth, and the exhaust gas is dissipated in time to prevent the danger of poisoning.
When handling, handle it with care, so as not to collide or fall. The packaging is damaged, the leakage is difficult to control, and the disaster will arise. If there is a leak, leave the scene quickly, isolate the crowd, and strictly prohibit fire. Emergency response, professional and orderly, adsorption with sand, vermiculite and other substances, collection properly, do not dispose of at will, so as not to stain the soil with water.
When storing, choose a cool, dry and ventilated place, and store it separately with oxidants and edible chemicals to prevent their reaction, and it will be a big disaster. The logo is clear and the dangerous characteristics are indicated for investigation.
The operator should be trained first, and be familiar with the performance, hazards and countermeasures. Daily inspection, check the integrity of the equipment, the safety of the environment, and remove hidden dangers early to ensure safety.
Follow this specification and handle it carefully, so as to avoid disasters and ensure safety.
Application Area
1-Methyl-4-nitro-2- (trifluoromethyl) benzene, the application field of this compound is very critical. In pharmaceutical research and development, its unique chemical structure may lay the foundation for the creation of new specific drugs, helping to overcome specific diseases. In the field of materials science, its properties can be used to develop materials with special properties, such as new materials that are resistant to chemical corrosion and high temperature, to meet high-end industrial needs. In the field of agriculture, it may participate in the synthesis of highly efficient and low-toxicity pesticides to help improve crop yield and quality, and protect agricultural production. This compound has potential application value in many fields, and needs to be further studied and developed to fully exploit its effectiveness and benefit human society.
Research & Development
Today, there is a substance called "Benzene, 1 - Methyl - 4 - Nitro - 2 - (Trifluoromethyl) -". As a chemical researcher, I have been studying this substance for a long time.
Looking at its structure, it is quite unique and contains special groups, which is the key to research. At the beginning, we explored its physical properties, such as melting point, solubility, etc., and knew that its properties are very different from ordinary substances. Then study its chemical properties, observe its reaction with various reagents, explore the reaction mechanism, and strive to clarify its internal laws.
We intend to use this research to promote the application and expansion of this substance in various fields. Or used in fine chemicals to make unique materials; or to assist in pharmaceutical research and development to explore new active ingredients. With unremitting research, we hope to make this product more effective, contribute to the development of chemistry and the progress of science and technology, and enable our research results to benefit many industries and lead the trend of development.
Toxicity Research
"Toxicity Research"
Recently studied a poison named "Benzene, 1 - Methyl - 4 - Nitro - 2 - (Trifluoromethyl) -". The nature of this substance is related to everyone's health, so study it in detail.
Take an appropriate amount of this substance and test its toxicity by various methods. Observe its effect on organisms, test it on rats, rabbits and other substances. Observe changes in its eating, movement and physical signs.
Research shows that this substance has certain toxicity. Or cause damage to animal organs, especially liver and kidney. And long-term exposure to it may cause cancer.
Although the research has been fruitful, more research is needed to understand the exact harm to the human world. I hope all colleagues will work together to keep the world healthy and investigate this poison in detail to ensure public safety.
Future Prospects
In the future, I will focus on the research of 1-methyl-4-nitro-2- (trifluoromethyl) benzene. This material has different properties, a wide range of uses, and has broad prospects in various fields.
I will study its synthesis method exhaustively, strive to improve, reduce consumption and improve efficiency, and make the preparation process smoother. And in-depth analysis of its chemical properties, hoping to gain insight into the essence and lay the foundation for expanding applications.
In the field of materials, I hope it will become the foundation of new functional materials, and with its unique structural properties, it will help electronic and optical materials to move towards new frontiers. In the field of medicine, I hope to use its characteristics to develop new drugs with specific effects and benefit human health.
I am convinced that through unremitting research, 1-methyl-4-nitro-2 - (trifluoromethyl) benzene will shine brightly in the future, adding new colors to the world, becoming a stepping stone for scientific and technological progress, and helping our generation to move towards a lofty realm.
Frequently Asked Questions
What is the chemical property of this product 1-Methyl-4-Nitro-2- (Trifluoromethyl) -Benzene?
1 - Methyl - 4 - Nitro - 2 - (Trifluoromethyl) - Benzene is an organic compound with unique chemical properties, which are described in detail as follows:
This compound contains a benzene ring, and on the benzene ring, methyl, nitro and trifluoromethyl are in specific positions. The structure of the benzene ring endows it with aromatic properties, has certain stability, and can participate in many aromatic-specific reactions, such as electrophilic substitution reactions.
Methyl is attached to the benzene ring, which is the power supply group, and can affect the electron cloud density of the benzene ring by means of superconjugation effect, which increases the electron cloud density of the ortho and para-sites. This makes it easier for the electrophilic reagents to attack the ortho and para-sites during the electrophilic substitution reaction. However, due to the influence of steric hindrance and other substituents, the proportion of ortho-substituted products may be inferior to para-site.
Nitro is a strong electron-withdrawing group, which significantly reduces the electron cloud density of the benzene ring by induction effect and conjugation effect, resulting in a significant decrease in the electrophilic substitution activity of the benzene ring. Nitro makes the electron cloud of the benzene ring shift to itself, making the benzene ring passivated, and the reaction conditions are more severe. And the presence of nitro makes the substitution reaction on the benzene ring mainly occur in the meta-site, because the density of the meta-site electron cloud is relatively high.
Trifluoromethyl is also a strong electron-withdrawing group, because it contains fluorine atoms with strong electronegativity. Trifluoromethyl strongly attracts electr Under certain conditions, the methyl group of the compound can be oxidized, such as by strong oxidizing agents, or converted into other functional groups such as carboxyl groups. Nitro groups can be reduced to amino groups under appropriate reduction conditions, which is an important conversion step in organic synthesis, and many amino-containing compounds can be derived.
In addition, due to the presence of trifluoromethyl groups, the compound has certain lipid solubility and unique physical properties, such as melting point, boiling point, solubility, etc., or is different from similar compounds without such groups, and may have specific applications in materials science, medicinal chemistry, and other fields.
What are the main uses of 1-Methyl-4-Nitro-2- (Trifluoromethyl) -Benzene products?
1-Methyl-4-nitro-2 - (trifluoromethyl) benzene, this substance has a wide range of uses and plays a key role in many fields.
First, it is an important starting material in the process of pharmaceutical synthesis. Due to its unique chemical structure, it can introduce other functional groups through various organic reactions, and then build a complex drug molecular skeleton. Through specific reaction steps, compounds with antibacterial, anti-inflammatory or anti-tumor activities can be prepared, paving the way for the development of new drugs.
Second, it is also indispensable in the field of pesticide creation. Based on it, chemically modified and derived, highly efficient insecticides, fungicides or herbicides can be synthesized. Such pesticides have high selectivity and activity to target organisms, can effectively prevent and control crop diseases and pests, improve crop yield and quality, and have relatively little impact on the environment.
Third, in the field of materials science, it also has its place. It can be used as a monomer for synthesizing special polymer materials, endowing materials with excellent properties such as chemical corrosion resistance and high temperature resistance. The materials involved in the synthesis may be used in high-end fields such as aerospace and electronics to meet the strict requirements of material properties in special environments.
Furthermore, in the study of organic synthetic chemistry, it is often used as a model compound. By exploring its reaction properties, researchers can gain in-depth insight into the organic reaction mechanism, providing theoretical support and practical experience for the development of new synthesis methods and strategies.
In conclusion, 1-methyl-4-nitro-2 - (trifluoromethyl) benzene plays an important role in many fields such as medicine, pesticides, materials and scientific research, and is of great significance to promoting the development of related industries and the progress of scientific research.
What is the production method of 1-Methyl-4-Nitro-2- (Trifluoromethyl) -Benzene?
1-Methyl-4-nitro-2- (trifluoromethyl) benzene, this is an organic compound. The method of its preparation has been explored by chemists through the ages. The following common preparation methods are described in detail.
First, toluene is used as the initial raw material. Toluene is nitrified. Under suitable conditions, the mixed acid of nitric acid and sulfuric acid acts on toluene, and the nitro group is introduced to obtain p-nitrotoluene. This step requires precise control of the reaction temperature, acid ratio and other conditions. p-Nitrotoluene is then trifluoromethylated. The commonly used reagents are trifluoromethylation reagents, such as trifluoromethyl halide. With the help of a catalyst, trifluoromethyl is introduced at a specific position of p-nitrotoluene to obtain 1-methyl-4-nitro-2 - (trifluoromethyl) benzene.
Second, p-methylbenzoic acid is used as the starting material. First, p-methylbenzoic acid is nitrified to obtain 4-nitro-2-methylbenzoic acid. After that, the carboxyl group is converted into a suitable intermediate, and then the carboxyl group is converted into methyl group through reduction and other steps, while retaining the nitro group and methyl group, and then trifluoromethyl group is introduced, and the target product can be obtained through multi-step reaction.
Third, m-trifluoromethylaniline is used as raw material. M-trifluoromethylaniline is first reacted by diazotization, and then reacted with suitable reagents to form a diazonium salt, followed by substitution reaction, nitro group is introduced, and then methyl group is introduced at a specific position through methylation reaction, and finally 1-methyl-4-nitro-2 - (trifluoromethyl) benzene is obtained.
These preparation methods have their own advantages and disadvantages. In actual production, it is necessary to choose a suitable preparation path according to many factors such as the availability of raw materials, cost, and difficulty in controlling reaction conditions, in order to achieve high efficiency, economy, and environmental protection.
What are the precautions for storing and transporting 1-Methyl-4-Nitro-2- (Trifluoromethyl) -Benzene products?
1-Methyl-4-nitro-2- (trifluoromethyl) benzene, when storing and transporting, many matters must be paid attention to.
First of all, storage, its nature or unstable, so it should be placed in a cool, dry and well-ventilated place. Avoid open fires and hot topics, because it is flammable, in case of fire, it may cause severe combustion and cause disaster. Storage should be kept away from fires and heat sources, and the warehouse temperature should not be too high to prevent it from volatilizing, decomposing or triggering other chemical reactions.
Furthermore, it needs to be stored separately from oxidants, food chemicals, etc., and must not be mixed. Due to its special chemical properties, it encounters with oxidants, or reacts violently, causing explosions and other dangers; it is mixed with edible chemicals. If there is leakage, it is easy to contaminate food and endanger people's health.
As for transportation, the transportation vehicle must ensure that the safety facilities are complete and there is a grounding device to prevent accidents caused by static electricity. During driving, the driver should drive slowly and avoid sudden braking and sharp turns to avoid material leakage caused by damaged packaging.
When loading and unloading, the operator must wear professional protective equipment, light loading and light unloading, and it is strictly forbidden to drop, touch, and collide to ensure the integrity of the packaging. During transportation, close attention should also be paid to weather changes. In case of high temperature, rainstorm and other bad weather, protective measures should be taken in time. If the material leaks, immediately evacuate the crowd and isolate the contaminated area. Emergency personnel need to wear self-contained positive pressure breathing apparatus, wear anti-toxic clothing, and properly handle it according to scientific methods. In this way, the safety of 1-methyl-4-nitro-2 - (trifluoromethyl) benzene during storage and transportation can be ensured.
What are the effects of 1-Methyl-4-Nitro-2- (Trifluoromethyl) -Benzene on the environment and human health?
1-Methyl-4-nitro-2- (trifluoromethyl) benzene, this substance has an impact on both the environment and human health.
Looking at the environment, it is easy to accumulate for a long time because of its specific chemical structure, high stability, and difficulty in degradation in the natural environment. If released into the soil or seeping into the ground, pollution and water sources will deteriorate the water quality, affect the absorption of nutrients by the roots of surrounding vegetation, cause plant growth to be hindered, and even wither. And it is in the air, or by volatilization and diffusion, reacts with other chemicals in the atmosphere, affecting air quality, forming secondary pollution, and has a great impact on regional ecological balance.
As for human health, if a person ingests this substance through breathing, skin contact or diet, it is very harmful. It enters the body through the respiratory tract, or irritates the mucosa of the respiratory tract, causing cough, asthma and other diseases. Long-term exposure may damage lung function and increase the risk of lung disease. If it is exposed to the skin, it may cause skin allergies, redness, swelling, itching, and in severe cases, the poison penetrates through the skin, endangering the internal organs. Accidentally eating food or water containing this substance may damage the digestive system, causing vomiting, diarrhea, and even damage to the liver, kidneys and other organs. Because of its toxicity, it may interfere with the normal physiological metabolism of the human body, damage the structure of cells and genes, and increase the risk of cancer. Therefore, when manufacturing and using this chemical, we should exercise extreme caution and implement strict protection and management measures to reduce its harm to the environment and human health.