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Benzene,1-Fluoro-4-Methoxy

Benzene,1-Fluoro-4-Methoxy

Hongda Chemical

Specifications

HS Code

232675

Chemical Formula C7H7FO
Molar Mass 126.13 g/mol
Appearance Liquid (predicted)
Boiling Point 174 - 176 °C at 760 mmHg (estimated)
Density 1.107 g/cm³ (estimated)
Vapor Pressure Low (due to relatively high boiling point)
Water Solubility Insoluble (hydrophobic aromatic compound)
Logp 2.24 (estimated, indicates lipophilicity)
Flash Point 60.7 °C (estimated)

As an accredited Benzene,1-Fluoro-4-Methoxy factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1 - fluoro - 4 - methoxybenzene packaged in a sealed, chemical - resistant bottle.
Storage Store “Benzene, 1 - fluoro - 4 - methoxy” in a cool, well - ventilated area, away from heat, sparks, and open flames as it may be flammable. Keep it in a tightly sealed container to prevent leakage and vapor release. Store separately from oxidizing agents and incompatible substances to avoid potential chemical reactions.
Shipping 1 - fluoro - 4 - methoxybenzene is shipped in accordance with strict chemical regulations. It's typically packed in corrosion - resistant containers, secured to prevent leakage during transit, and transported by carriers trained in handling hazardous chemicals.
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Benzene,1-Fluoro-4-Methoxy Benzene,1-Fluoro-4-Methoxy
General Information
Historical Development
Wenfu Benzene, 1 - Fluoro - 4 - Methoxy, the origin of its exploration, is really an important sign of chemical evolution. In the past, all the sages worked diligently in the field of organic matter, hoping to understand the mysteries of matter.
At first, everyone's understanding of aromatic compounds was still shallow, and only a little bit of their basic properties were known. After many experiments, analyzing its structure and exploring its reaction, the properties of such substances were gradually clarified.
As for Benzene, 1 - Fluoro - 4 - Methoxy, early or hidden in complex chemical reaction products, has not been carefully studied. However, with the advancement of analytical technology, chemists were able to accurately identify, purify, and clarify its chemical composition and structure. The discovery of this substance is just like the entry of new streams in the long river of chemistry, enriching the organic chemical system, paving a new way for subsequent research and application, and also expanding the field of chemistry.
Product Overview
"Description"
Today there is a thing named "Benzene, 1-Fluoro-4-oxMethy". Its color, under the constant pressure, or in the liquid, is clear and transparent, as if it were clear water. Its color, the color and the shimmer, just like the morning dew reflects the sun.
To study its properties, this is a chemical compound. Its chemical structure is composed of a phenyl group, a fluorine atom, and a methoxy group. The two are related to each other, which makes this substance special. In the chemical reaction, due to the determination of benzene, and the activity of the fluorine methoxy group, it can often be synthesized in many ways, or as a raw material, or as a medium, use.
It has a slightly aromatic aroma, but it is not a pleasant fragrance, but there is a risk of slight toxicity. If you inhale it carelessly, or if you are exposed to the skin, you may be afraid of burning your body. It is necessary to handle this thing, so as to follow the rules, to prevent danger.
Physical & Chemical Properties
1-Fluoro-4-methoxybenzene, the physical and chemical properties of this substance are related to many aspects. Its appearance may be colorless and transparent, with a special odor. In terms of physical properties, the melting point and boiling point have fixed numbers, and there are different solubilities in different solvents. In terms of chemical properties, because of its fluorine and methoxy groups, fluorine atoms have strong electronegativity, which changes the electron cloud density of the benzene ring and affects the electrophilic substitution reaction activity; methoxy groups are the power supply groups, which also affect the reactivity. This compound is widely used in the field of organic synthesis and can be prepared by various paths. The study of its physical and chemical properties is of great significance for optimizing the synthesis process and expanding the application range.
Technical Specifications & Labeling
"Technical Specifications and Labeling of 1-Fluoro-4-Methoxylbenzene (Commodity Parameters) "
The technical specifications of 1-fluoro-4-methoxylbenzene are related to many. This substance has a specific chemical composition and a well-established molecular structure. In production and preparation, precise processes are required, raw materials must be selected pure, reaction conditions are strictly controlled, parameters such as temperature, pressure, time, etc., with no tolerance in the millimeter.
In terms of identification, the commodity parameters are clear. Its name is "1-fluoro-4-methoxylbenzene", and the chemical symbol is also accurately defined. On the packaging, labels should be displayed, including names, ingredients, warnings, etc., to inform users of risks and precautions, and to ensure safe operation and correct quality.
Preparation Method
To prepare 1-fluoro-4-methoxy benzene (Benzene, 1-Fluoro-4-Methoxy), the raw materials, production process, reaction steps and catalytic mechanism are the key.
First take p-methoxy phenol as raw material, and react with an appropriate amount of inorganic bases such as sodium hydroxide to form phenols. This step is to activate the phenolic hydroxyl group to facilitate subsequent reactions. Then, fluorinated reagents, such as potassium fluoride, are introduced into a specific organic solvent such as dimethyl sulfoxide (DMSO), heated and stirred. In this environment, fluoride ions are nucleophilic substitution reaction, replacing the oxygen atoms connected to the hydroxyl groups in the phenolic salt, and then the target product is obtained.
The reaction step requires strict control of temperature and reaction time. If the temperature is too low, the reaction will be slow; if the temperature is too high, or side reactions will occur. If the time is insufficient, the raw material will not be fully converted; if the time is too long, the energy consumption will increase and the product may be decomposed.
In terms of catalytic mechanism, the organic solvent DMSO can effectively dissolve the reactants, enhance the ionic activity and promote the reaction. At the same time, the selection and dosage of inorganic bases also have a significant impact on the reaction rate and product purity. Through these controls, 1-fluoro-4-methoxylbenzene can be efficiently prepared.
Chemical Reactions & Modifications
Nowadays, there is a chemical substance called "Benzene, 1 - Fluoro - 4 - Methoxy". The reaction and modification of chemistry are often studied by our chemistry researchers.
The chemical reaction of this "Benzene, 1 - Fluoro - 4 - Methoxy" is related to the structure and bond energy of the molecule. The position of fluorine and methoxy groups in the benzene ring causes the distribution of electron clouds to be different, which affects the reactivity.
The way of modification may introduce other groups to change its chemistry. For example, select the appropriate reagent, through nucleophilic substitution or electrophilic substitution reaction, change its substituent group, and then adjust its physical and chemical properties. All this depends on fine experiments and profound theory, so that this chemical can be used in various fields, such as materials and medicine. It is expected to become a new quality and open up new avenues for scientific research.
Synonyms & Product Names
1-Fluoro-4-methoxybenzene, also known as p-fluoroanisole. Its alias and trade name are commonly used in the field of chemistry. P-fluoroanisole is quite useful in chemical synthesis. It can be used as a raw material to participate in various organic synthesis reactions; or as a solvent to help the smooth progress of the reaction. It has also been involved in the preparation of fragrances and the manufacture of medicines. Ancient scholars discussed various chemical substances, although they did not have the accurate understanding of modern times, they did not lack the spirit of inquiry. Today we are exploring the aliases and trade names of 1-fluoro-4-methoxybenzene, with the aim of clarifying its many titles in the chemical industry, so as to facilitate communication and application. In this way, it allows the industry to know its name and its products, and to move freely on the road of production and research and development, thus promoting the progress of the chemical industry.
Safety & Operational Standards
About "1-fluoro-4-methoxybenzene" product safety and operating specifications
"1-fluoro-4-methoxybenzene" is a common substance in chemical research. In its experimental and production process, safety and operating standards are of paramount importance.
The first word is safe. This substance has a certain chemical activity and can be dangerous in case of open flames, hot topics or. Therefore, when storing, it should be placed in a cool and well-ventilated place, away from fire and heat sources. And it should be stored separately from oxidants, acids, etc., and should not be mixed to prevent violent chemical reactions. When taking it, the experimenter must wear appropriate protective equipment, such as protective clothing, gloves and goggles, to prevent it from contacting the skin and eyes, causing burns and other injuries. In case of inadvertent contact, rinse immediately with plenty of water and seek medical attention in time.
The following operating specifications. During the experimental operation, it needs to be carried out in a fume hood to ensure that harmful gases are discharged in time and will not endanger the health of the experimenter. When operating, the action should be steady and accurate to avoid spilling and leakage. If there is a leakage, the unrelated personnel should be quickly evacuated to a safe area and isolated. Small leaks can be absorbed by inert materials such as sand and vermiculite; if there are large leaks, they need to be built with embankments or dug for containment, and transferred to a special container with an explosion-proof pump for proper disposal.
Furthermore, the equipment and equipment using this substance must be checked and maintained regularly to ensure that its performance is good and there are no safety hazards such as leakage. Operators should also be professionally trained and familiar with its characteristics, safety precautions and emergency handling methods before they can operate.
In short, when dealing with "1-fluoro-4-methoxybenzene", only by strictly observing safety and operating standards can the experiment be smooth, the production is safe, and the safety of the experimenter and the surrounding environment can be protected.
Application Area
"On the application field of 1-fluoro-4-methoxybenzene"
1-fluoro-4-methoxybenzene is very useful in various application fields. In the field of pharmaceutical synthesis, this compound is often a key raw material. With its unique structure, it can participate in the construction of a variety of drug molecules, providing assistance for the development of new drugs and the treatment of various diseases. For example, in the development of therapeutic drugs for certain neurological diseases, 1-fluoro-4-methoxybenzene is integrated into the molecular structure of the drug through delicate chemical reactions, so that the drug can act more accurately on the target and improve the efficacy.
Furthermore, in the field of materials science, it also has outstanding performance. It can be a basic component for the preparation of materials with special properties. After specific processing, the material can have excellent optical properties or electrical properties, such as excellent optical properties, which can make a name for itself in the field of optoelectronic materials, and help the progress and innovation of related technologies. Therefore, 1-fluoro-4-methoxybenzene is of great value in the application fields of medicine and materials, opening up new avenues for many research and practice.
Research & Development
There is a substance today called "Benzene, 1 - Fluoro - 4 - Methoxy". I am a chemical researcher, observing the characteristics of this substance and studying the reasons for its changes.
In the laboratory, I investigated its structure in detail and observed its reaction under different conditions. The properties of this substance are unique, and the position of fluorine and methoxy groups has a great impact on its activity. After repeated experiments, we have obtained a lot of data to clarify its reaction law.
We hope that through research, this substance will be widely used in industry, medicine and other fields. If its characteristics can be accurately grasped, better products may be produced, which will promote the development of related industries. Over time, we will be able to borrow the research results of "Benzene, 1 - Fluoro - 4 - Methoxy" to add to the field of chemistry and open up new frontiers.
Toxicity Research
The chemical industry is related to people's livelihood, and the study of toxicants is particularly important. Today, when it comes to Benzene, 1-Fluoro-4-Methoxy, its toxicity research should not be ignored.
Observing the test of all kinds of poisons in the past, we have carefully observed their nature, behavior between things, and various effects. In terms of Benzene, 1-Fluoro-4-Methoxy, one should study it. First, the way into the body, either through the mouth and nose, or through the skin. Second, the changes in the body, biochemical reactions, and the influence of the viscera. Third, long-term exposure can cause chronic diseases, and even the possibility of future generations.
Toxicity research is related to human life and the safety of the environment. Only by conducting in-depth research and understanding the details of its toxicity can we determine preventive measures to ensure the well-being of everyone and protect the peace of the world.
Future Prospects
Guanfu Benzene, 1 - Fluoro - 4 - Methoxy Although the current knowledge is limited, it has great expectations for future development. At present, chemical research is changing with each passing day, and new technologies are emerging one after another.
In time, our generation may be able to gain insight into its wonders in the field of medicine, and with its unique structure, it may help to develop effective medicines and cure all kinds of diseases. On the industrial level, it may be possible to optimize the process, increase output, reduce costs and increase efficiency, and contribute to the development of the industry.
Furthermore, in materials science, it may also give birth to new materials with specific properties and be applied to high-tech. Although the road ahead is long, the heart of scientific research is endless, and the pace of exploration is endless. We firmly believe that the future will be able to unveil its mysteries, bloom its brilliant brilliance, and create unparalleled achievements for the well-being of mankind.
Where to Buy Benzene,1-Fluoro-4-Methoxy in China?
As a trusted Benzene,1-Fluoro-4-Methoxy manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading Benzene,1-Fluoro-4-Methoxy supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of 1-fluoro-4-methoxybenzene?
What are the chemical properties of 1 + -jiang-4-acetoxybenzene?
1 + -jiang-4-acetoxybenzene, this expression may not be accurate. It is speculated that what you want to say may be p-acetoxybenzene related substances. The following is an example of p-acetoxybenzene to briefly describe its chemical properties:
p-acetoxybenzene, often refers to p-acetoxystyrene. Its molecules contain phenyl rings, carbon-carbon double bonds, and ester groups. Because of its carbon-carbon double bonds, addition reactions can occur. For example, under suitable catalyst and reaction conditions, it can undergo an addition reaction with hydrogen to convert carbon-carbon double bonds into single bonds and generate corresponding saturated compounds; it can also be added with halogen elementals (such as bromine water), and bromine atoms are added to the carbon atoms at both ends of the double bond to fade bromine water. This reaction can be used to identify the existence of carbon-carbon double bonds in molecules.
Due to the presence of ester groups, p-acetoxybenzene can undergo hydrolysis. Under acidic conditions, hydrolysis generates p-hydroxystyrene and acetic acid; under alkaline conditions, hydrolysis is more thorough, generating salts of p-hydroxystyrene and acetate.
In addition, due to the electronic effect of the benzene ring and the carbon-carbon double bond, the hydrogen atom on the benzene ring has a certain activity and can undergo a substitution reaction. For example, under the action of a suitable catalyst, it can undergo a halogenation reaction with a halogenating agent, and the halogen atom replaces the hydrogen atom on the benzene ring. The benzene ring in the molecule of p-acetoxybenzene can also undergo a nitration reaction, and react with concentrated nitric acid under the catalysis of concentrated sulfuric acid to generate the corresponding nitro substitution product. Due to the coexistence of multiple unsaturated bonds in its structure, p-acetoxybenzene can also participate in the polymerization reaction. Under the action of the initiator, the carbon-carbon double bond is opened and connected to each other to form a polymer. These chemical properties make p-acetoxybenzene widely used in many fields such as organic synthesis and polymer material preparation.
What are the physical properties of 1-fluoro-4-methoxybenzene?
"Tiangong Kaiwu" says: "What are the physical properties of 1 + -jiang-4-methoxybenzene?"
This thing is also, the color state is often colorless to light yellow liquid, and it is quite stable under normal temperature and pressure. Looking at its smell, it often has a faint aromatic smell, and it feels fresh when smelled. Its boiling point is within a certain temperature range, which varies slightly depending on the specific structure and environment, roughly around a few degrees Celsius. This temperature makes it gradually change from liquid to gaseous when heated.
Furthermore, its density is also one of the important physical properties. Compared with water, it has a specific value, which makes its sinking and floating state in water different. And the solubility also has characteristics, in some organic solvents such as ethanol and ether, it can be better dissolved, but in water the solubility is not good, only slightly soluble or insoluble.
In addition, the refractive index of this substance also has a certain value. When light passes through, the propagation direction of light changes according to this value. This property may be considered in optical related research and applications.
In summary, 1 + -jiang-4-methoxy benzene has so many physical properties, and its application in many fields such as chemical industry and medicine also depends on its unique physical properties to perform different functions.
In what fields is 1-fluoro-4-methoxybenzene used?
1+-+%E6%B0%9F+-+4+-+%E7%94%B2%E6%B0%A7%E5%9F%BA%E8%8B%AF, that is, 1-butene-4-methoxybenzene, which has applications in many fields.
In the field of pharmaceutical synthesis, it is a key organic synthesis intermediate. Because of its unique chemical structure and activity, it can participate in many complex chemical reactions and help build a diverse drug molecular skeleton. Taking the synthesis of some cardiovascular disease therapeutic drugs as an example, 1-butene-4-methoxybenzene can introduce key functional groups through specific reaction steps, and then shape the drug structure with precise pharmacological activity, which plays an important role in improving cardiovascular function, regulating blood pressure and blood lipids.
In the field of materials science, it also shows important value. It can be used as a monomer to participate in the synthesis of polymer. Through polymerization, 1-butene-4-methoxybenzene can be combined with other monomers to form polymer materials with special properties. For example, the synthesized polymer may have good thermal stability, mechanical properties or optical properties, etc., and can be used to make high-performance engineering plastics, optical fibers and other materials, which are widely used in high-end technology industries such as electronics and aerospace.
In the fragrance industry, 1-butene-4-methoxybenzene can be used as a fragrance component due to its special smell. Its unique aroma provides the possibility to formulate complex and unique fragrance formulations, imparting a unique fragrance to perfumes, air fresheners, detergents and other products, enhancing the olfactory experience and market competitiveness of products.
In the field of organic synthetic chemistry, it is an important starting material or intermediate, participating in a series of organic reactions. Through addition, substitution, oxidation and other reactions with different reagents, a wide variety of organic compounds can be constructed, providing a rich material basis for the development and innovation of organic synthetic chemistry, and promoting the development and exploration of new compounds.
What are the synthesis methods of 1-fluoro-4-methoxybenzene?
The synthesis methods of 1 + -jiang-4-acetoxybenzene are as follows:
First, benzene is used as the starting material. First, the benzene is acetylated, and the acetyl group is introduced on the benzene ring. The commonly used acetylation reagent is acetyl chloride or acetic anhydride. Under the catalytic action of Lewis acid such as aluminum trichloride, benzene reacts with the acetylation reagent to form acetylbenzene. Subsequently, under certain conditions, the hydroxylation reaction of acetylbenzene is carried out. By using a suitable peroxide under the action of a suitable oxidizing agent, such as in a specific solvent system, hydroxylation occurs at the position of the acetyl group on the benzene ring, thereby obtaining 4-acetoxybenzene.
Second, phenol is used as the starting material. Phenol is first esterified with acetic anhydride in the presence of basic catalysts such as pyridine. The acetyl group of acetic anhydride replaces the hydrogen atom on the phenol hydroxyl group to directly generate 4-acetoxybenzene. This method is relatively simple, and the reaction conditions are relatively mild, which requires relatively little equipment.
Third, it can also be started from p-hydroxyacetophenone. P-hydroxyacetophenone reacts with suitable acylating reagents under suitable reaction conditions. For example, in a mild alkaline environment and a suitable solvent, the hydroxyl group of p-hydroxyacetophenone can be acetylated by reacting with acylating reagents such as acetyl chloride, and finally 4-acetoxybenzene can be obtained.
The above synthesis methods have their own advantages and disadvantages. In practical applications, it is necessary to comprehensively weigh various factors such as specific production requirements, raw material availability, cost considerations, and controllability of reaction conditions to choose the most suitable synthesis path.
What are the environmental effects of 1-fluoro-4-methoxybenzene?
The impact of methylhydroxybenzene on the environment is a topic worthy of investigation.
If methylhydroxybenzene exists in the environment, its impact is quite complex. In aquatic ecosystems, it may have toxic effects on aquatic organisms. Because of the chemical structure of methylhydroxybenzene, it may interfere with the physiological metabolic process of aquatic organisms. For example, it may affect the respiration of fish, causing fish to encounter obstacles when absorbing oxygen, which in turn affects their survival and reproduction. And for aquatic plants, it may also interfere with their photosynthesis, making plants unable to synthesize nutrients normally, and ultimately affecting the balance of aquatic ecosystems.
In the soil environment, methyl hydroxybenzene may affect the soil microbial community. Soil microorganisms play a key role in the material cycle and nutrient transformation of the soil. The presence of methyl hydroxybenzene may change the type and quantity of microorganisms. Some microorganisms that are sensitive to it may decrease, while some microorganisms that are tolerant may increase. This change will further affect the fertility and structure of the soil, such as affecting the soil's ability to maintain and release nutrients, and changing the physical properties of the soil.
In the atmospheric environment, if methyl hydroxybenzene volatilizes into the atmosphere, it may participate in photochemical reactions. It interacts with other substances in the atmosphere and may generate secondary pollutants, such as ozone. The increase in ozone concentration not only causes damage to the human respiratory system, causing symptoms such as cough and asthma, but also causes damage to plant leaves and inhibits plant growth.
In addition, the degradation process of methyl hydroxybenzene cannot be ignored. In the natural environment, its degradation rate may be restricted by many factors, such as temperature, humidity, microbial species, etc. If the degradation is slow, it will continue to accumulate in the environment, which will cause more serious long-term effects on the environment.
From this perspective, 1 + -jiang-4-methyl hydroxybenzene has a significant impact on the environment at multiple levels, and it needs to be paid close attention and in-depth research to explore countermeasures and maintain the stability of the ecological environment.