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Benzene, 1-Fluoro-3-Nitro-

Benzene, 1-Fluoro-3-Nitro-

Hongda Chemical

Specifications

HS Code

887468

Chemical Formula C6H4FNO2
Molar Mass 141.1 g/mol
Appearance Yellow - solid
Melting Point 52 - 54 °C
Boiling Point 232 - 234 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Flash Point 105.6 °C

As an accredited Benzene, 1-Fluoro-3-Nitro- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1 - fluoro - 3 - nitro - benzene packaged in a sealed, chemical - resistant bottle.
Storage 1 - fluoro - 3 - nitrobenzene should be stored in a cool, well - ventilated area away from heat, sparks, and open flames. It should be kept in a tightly sealed container, preferably made of corrosion - resistant materials like glass or certain plastics. Store it separately from oxidizing agents and reducing agents to prevent potential chemical reactions. Ensure proper labeling for easy identification and handling.
Shipping 1 - fluoro - 3 - nitro - benzene is shipped in tightly sealed, corrosion - resistant containers. Compliance with hazardous chemical regulations is crucial. Shipment often involves proper labeling, and transport by carriers trained in handling such chemicals.
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Benzene, 1-Fluoro-3-Nitro- Benzene, 1-Fluoro-3-Nitro-
General Information
Historical Development
1-Fluoro-3-nitrobenzene is also an organic compound. At the beginning, chemists gradually gained insight into the characteristics of this compound in the process of exploring organic structures and reactions. At first, it was limited to technology and cognition, and its understanding was still shallow.
However, with the passage of time and the advancement of science and technology, researchers analyzed its structure in an exquisite way, and it was clear that it was derived from a benzene ring, and fluorine and nitro groups replaced hydrogen atoms at a specific position. This structure gives it a unique chemical activity.
With the advancement of chemical synthesis technology, the preparation of 1-fluoro-3-nitrobenzene became more and more mature. Chemists use various reaction pathways to synthesize this compound under control, and explore its application potential in the fields of medicine, materials, etc. The hazy cognition of the past is gradually replaced by clear cognition and diverse applications. Its historical evolution has also witnessed the vigorous development of chemistry.
Product Overview
"Overview of 1-Fluoro-3-nitrobenzene Products"
Fu 1-fluoro-3-nitrobenzene is a member of organic compounds. It has a unique structure, with fluorine atoms and nitro groups in interposition above the benzene ring.
Looking at its physical properties, at room temperature, it may be a colorless to light yellow liquid with a special odor. Its boiling point, melting point and other physical constants are the keys to characterize its characteristics. In terms of chemical properties, due to the introduction of fluorine atoms and nitro groups, the electron cloud density of the benzene ring changes, and its activity is also different from that of benzene. Nitro has strong electron-absorbing properties, which makes this compound prone to nucleophilic substitution reactions; although fluorine atoms also have electron-absorbing effects, their special atomic radius and electronegativity also affect the reaction path.
In the industrial field, 1-fluoro-3-nitrobenzene is often an important intermediate in organic synthesis. It can be prepared by a variety of ways, such as using benzene as the starting material and through a series of reactions such as nitrification and halogenation. It is widely used in medicine, pesticides, dyes and other industries, or is a key building block for the synthesis of new drugs, or plays an important role in the creation of pesticides, making great contributions to the development of the chemical industry.
Physical & Chemical Properties
1-Fluoro-3-nitrobenzene is also an organic compound. Its physical and chemical properties are worth studying.
Looking at its physical properties, at room temperature, 1-fluoro-3-nitrobenzene is in a liquid state, colored or light yellow, with a special odor. Its boiling point and melting point are both characteristics. The boiling point is related to the temperature of gasification, and the melting point is related to the transformation of solid and liquid states. Density is also its physical characterization, which is related to the floating and sinking properties of substances.
On its chemical properties, the substitution of fluorine atoms and nitro groups on the benzene ring makes its chemical activity unique. Nitro groups have strong electron-absorbing properties, and fluorine atoms also have unique electronic effects. The synergy between the two makes this compound have different reactivity and selectivity in electrophilic substitution, nucleophilic substitution and other reactions. In many organic synthesis paths, 1-fluoro-3-nitrobenzene can lead to the preparation of various organic products due to its physicochemical properties, or as a key intermediate, and its role is obvious in the field of organic chemistry.
Technical Specifications & Labeling
Today's study of Benzene, 1 - Fluoro - 3 - Nitro - this product, the process specifications and identification (commodity parameters) are the key. The process specifications are related to the production method, and must follow the precise process, from the selection of raw materials to the control of reaction conditions, such as temperature and pressure. The identification (commodity parameters) indicates its characteristics, such as the chemical structure must be accurate, and the physical properties such as color, taste and state must also be detailed.
To make this product, the proportion of raw materials must be accurate, and the reaction time should also be appropriate. And the detection method should be reliable to determine its purity and impurity content. In terms of identification, its chemical name is standardized, and the molecular formula is accurate, which is the right way. In this way, the quality of Benzene, 1 - Fluoro - 3 - Nitro - products can be guaranteed to meet the requirements of the required process specifications and identification (product parameters).
Preparation Method
To prepare 1-fluoro-3-nitrobenzene, it is necessary to clarify the method of its preparation. The first is the choice of raw materials, when using benzene as a group, supplemented by fluoride and nitrobenzene. The key to the process is to use the method of nitrogenation to introduce nitro into the benzene ring to obtain m-nitrobenzene. The method is to mix sulfuric acid and nitric acid, so that benzene can respond to it, and the temperature is controlled and controlled, so that the reaction is better.
Then the step of fluorination is carried out. In this step, a suitable fluorinating agent, such as potassium fluoride, etc., should be used to react with m-nitrobenzene, and a phase transfer catalyst must be used to help it react. The reaction conditions are also strict, such as temperature and solvent are fixed.
To control the process of the reaction, each step should be completed, and the pure product must be obtained by separation and purification methods, such as extraction, distillation, recrystallization, etc. And in the whole process, it is appropriate to set up a monitoring mechanism to ensure that the reaction is as expected, and the quality and quantity of the product are as desired. This is the approximate process for making 1-fluoro-3-nitrobenzene.
Chemical Reactions & Modifications
The reaction and denaturation of 1-fluoro-3-nitrobenzene are of great importance to chemical researchers. The reaction of fluorine and nitro groups can lead to various changes. The activity of fluorine can be easily connected to the benzene ring, and the strong absorption of nitro groups changes the electron cloud of the benzene ring.
In electrophilic substitution, the absorption of nitro groups causes the electron cloud of the benzene ring to drop tightly, which makes the attack of electrophilic reagents different. Although fluorine also has the effect of absorbing electricity, its p-π conjugate can increase the adjacent electron cloud, so the check point should be studied in detail.
If you want to improve its properties, you can change the conditions, such as temperature regulation, pressure regulation, and catalyst selection. In this way, it can promote the reaction to the desired product, increase the yield and selectivity. And studying its reaction mechanism can clarify the intermolecular interaction, which is of great significance to the chemical industry.
Synonyms & Product Names
1-Fluoro-3-nitrobenzene (Benzene, 1-Fluoro-3-Nitro -) is the same trade name as our chemical research note.
1-fluoro-3-nitrobenzene, also known as fluoro-nitrobenzene. It is used in the field of chemical synthesis. Due to its unique chemical properties, it is often used as an important raw material or medium in many synthetic reactions.
As for the trade name, it may vary depending on the market. However, it does not refer to this specific chemical. We researchers need to identify the same trade names in order to operate in research and production, and to promote the progress of chemical science for the benefit of the world.
Safety & Operational Standards
Safety and operating regulations of monofluorotrinitrobenzene
For the use of monofluorotrinitrobenzene, it is also a chemical research object. At the time of experimental research, its safety and operating regulations are of paramount importance and must not be ignored.
The most important thing for safety is protection. Those involved in this object should be equipped with complete protective equipment. For eye protection, you need to wear special goggles to prevent this object from splashing in and damaging your eyes. For body protection, you need protective clothing, which is dense and strong, and can prevent it from seeping. You also need to wear protective gloves on your hands. The material is resistant to corrosion and should not touch the skin.
Furthermore, there are strict regulations where it is stored. It should be placed in a cool, dry and well-ventilated place. Keep away from sources of fire and heat to avoid the danger of deflagration. And it needs to be separated from other things, especially avoid coexisting with reduced things to prevent them from causing violent reactions.
When operating, the regulations are also complex. First, the experimental device must be clean and dry, free from impurities. When measuring this thing, use a precise device and measure it according to the regulations, and do not exceed it. When mixing, the action should be slow, and stir while mixing, so that it should be uniform and stable.
The process of reaction, closely observe. Changes in temperature and pressure, always pay attention. If the temperature rises sharply and the pressure is high, quickly adopt control strategies to prevent accidents. Waste gas and waste liquid should not be discharged indiscriminately, and they should be properly disposed of in accordance with environmental protection regulations.
In addition, the operator must understand emergency measures. If there is a splash, quickly rinse with water, followed by special medicine. If a fire starts, use suitable extinguishing materials and extinguish according to its nature.
In short, the safety and operation regulations of monofluorotrinitrobenzene are must be followed by chemical researchers. Only by observing these regulations can we ensure the safety of research and promote the progress of the industry.
Application Area
1-Fluoro-3-nitrobenzene (Benzene, 1 - Fluoro - 3 - Nitro -) is an organic compound. Its application field is quite wide. In the field of pharmaceutical synthesis, it can be used as a key intermediate to help create new drugs and cure various diseases. Due to its special chemical structure, it can cleverly react with other substances to generate ingredients with specific pharmacological activities.
In the field of materials science, it also has important functions. It can participate in the preparation of high-performance materials, such as special engineering plastics. After chemical modification, it can give materials unique properties, such as higher heat resistance and corrosion resistance, making it suitable for extreme environments.
And it also plays an important role in dye synthesis. Through specific chemical reactions, colorful and high-performance dyes can be derived, which can be used in fabric printing and dyeing and other industries to add color to life. From this perspective, 1-fluoro-3-nitrobenzene has shown extraordinary value in many fields, promoting the progress and development of related industries.
Research & Development
I am committed to the study of 1-fluoro-3-nitrobenzene. This substance has a unique structure and unique properties, and has great potential in the field of organic synthesis.
At first, explore the method of its synthesis. After various attempts, a certain method can be obtained, but the yield is not ideal. Then he dedicated himself to studying, improving the process, optimizing the conditions, and finally increasing the yield.
Then study its reaction characteristics. Examine its reaction with various reagents, analyze the mechanism in detail, and clarify its activity check point, laying the foundation for subsequent derivatization.
The stability of 1-fluoro-3-nitrobenzene is also tested, and its changes are observed in different environments, and it is known that it is affected by temperature, light, humidity, etc.
Today, although 1-fluoro-3-nitrobenzene has made progress, there are still challenges. In the future, we should continue to improve and expand its application, hoping that it will shine in the fields of materials, medicine, etc., so as to achieve new frontiers of research and development.
Toxicity Research
Today, there is a substance called "1-fluoro-3-nitrobenzene", which is very important in the field of chemical research. The structure of this substance is unique, fluorine and nitro are connected to the benzene ring. Fluorine is active, nitro is highly oxidizing, and the two are combined in the benzene ring, or cause its special toxicity.
According to experimental observations, it may damage the cells of organisms. In animal experiments, after the test organisms are contaminated with this substance, the physiological functions are occasionally abnormal. Organ lesions may be seen, or the nervous system may be affected. However, the exact mechanism of its toxicity still needs to be further explored. We should carefully investigate each reaction link to understand its metabolic pathway in the body of organisms and identify which is toxic. Ji Neng fully understands the toxicity of this "1-fluoro-3-nitrobenzene", provides evidence for protection and application, and uses it to avoid its harm.
Future Prospects
Prospects for the future, in the field of 1-fluoro-3-nitrobenzene, it is the most important research trend. Its properties are unique, or there are new developments in many fields.
This compound, its delicate, fluoro-nitro, and its properties. The basis for research and development, or it can be made for special effects, with its special reaction, specific diseases, new methods.
In the field of materials, 1-fluoro-3-nitrobenzene may be able to produce new functional materials, increase the properties of materials, and use it in the fields of electronics, aerospace, etc., to promote its progress.
Furthermore, the catalytic field is also expected to improve its characteristics and become a high-efficiency catalyst, reducing energy consumption, improving efficiency, and promoting innovation in chemical engineering. In addition, the scene of 1-fluoro-3-nitrobenzene, and we are doing our best to explore its capabilities.
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Frequently Asked Questions

As a leading Benzene, 1-Fluoro-3-Nitro- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of this product 1-fluoro-3-nitrobenzene
"Tiangong Kaiwu" was written by Song Yingxing in the Ming Dynasty. If "the chemical properties of this product 1-jiang-3-choline" are discussed, it should be described in the style of ancient words.
Choline is mild in nature and often has a unique state in various chemical changes. It is an organic base that can combine with acids to form a genus of salts. Looking at its structure, the nitrogen-containing group is connected to the hydroxyl group, which gives it special chemical activity.
When encountering a strong acid, choline can react quickly with it, and the nitrogen atom accepts protons by virtue of its lone pair of electrons, thus forming a stable cationic structure. This salt compound has good solubility in water and can be uniformly dispersed in the liquid phase in an ionic state.
In the oxidation reaction, choline also shows. Its hydroxyl part can be oxidized to an aldehyde group or even a carboxyl group under suitable conditions, such as strong oxidizing agents. However, this process requires specific temperature, catalyst and other conditions to cooperate, and it can occur non-arbitrarily.
Furthermore, between choline molecules, due to the action of hydrogen bonds, a certain aggregation state can be formed. In the solid state, the intermolecular force maintains the stability of the structure, and when heated to a certain extent, after overcoming this force, it can be converted into a liquid state, exhibiting the characteristics of thermally induced phase transition.
And choline can act as a supporting role for catalysts or reactants in some specific organic reaction systems, affecting the rate and path of the reaction. Its chemical properties are diverse, and it is manifested in various chemical processes.
What are the main uses of 1-fluoro-3-nitrobenzene?
3-Aminopyridine, its main uses are as follows:
First, in the field of drug synthesis, 3-aminopyridine is a key intermediate. Because of its unique chemical structure and activity, it can participate in the construction of many drug molecules. For example, in the preparation of many anti-infective drugs, 3-aminopyridine can be introduced into the drug molecular structure through specific chemical reactions, giving the drug unique pharmacological activity, helping the drug to inhibit or kill pathogens, and then exert the effect of treating infectious diseases.
Second, in the field of materials science, 3-aminopyridine also plays an important role. It can be used to synthesize polymer materials with special properties. By polymerizing with other monomers, polymers with specific electrical, optical or mechanical properties can be prepared. For example, the synthesized polymers may have good electrical conductivity and can be used in organic electronic devices, such as organic Light Emitting Diodes (OLEDs), organic solar cells, etc., to provide new material options for the development of these fields.
Third, in the field of pesticide creation, 3-aminopyridine can be used as a starting material to synthesize new pesticides. Using its chemical properties, compounds with efficient pest control effects can be synthesized. Such compounds may control the population of pests and protect crops from insect attacks by interfering with the physiological and metabolic processes of pests, nervous systems, etc., providing protection for the harvest of agricultural production. Fourth, in the field of organic synthetic chemistry, 3-aminopyridine, as an important nitrogen-containing building block, is widely used in the construction of various complex organic molecules. It can be combined with other organic reagents through a variety of chemical reactions, such as nucleophilic substitution, cyclization, etc., to construct organic compounds with different structures and functions, providing organic synthetic chemists with rich synthesis strategies and diverse molecular structure design possibilities.
What is the production method of 1-fluoro-3-nitrobenzene?
"Tiangong Kaiwu" is a scientific and technological masterpiece written by Song Yingxing in the Ming Dynasty. It does not contain the "production method of 1 + - + Jiang-3-aminobenzene" in detail. However, although the ancients did not have the method of modern fine chemical synthesis, they had the idea of transformation based on natural raw materials and simple processes. Today, the method is tried in ancient Chinese.
If you want to make this thing, you should start with natural benzene-containing minerals or plants. Find the stone containing benzene and calcine it with fire. Choose a stainless steel kettle, place the stone in it, and seal it with clay, so as not to let air vent. When burning the charcoal, the fire should be fierce and even. When the stone melts and the gas comes out, use a copper tube to guide the gas into the cold water urn, so that the gas can be condensed into a liquid, which may contain benzene.
Then take the water from the river, after repeated precipitation and filtration, remove its sediment and debris, and take the clean one. Mix the liquid and water in a bamboo utensil in a certain proportion and put it into the crock. Then take plant ash, leach it to obtain lye, slowly inject it into the tank, stir it evenly, and boil it slowly over warm heat. During this period, pay close attention to changes in the heat and state of matter, and adjust it in a timely manner.
Wait for changes in the contents of the tank, or precipitation, or color change, and let it stand. After it cools, filter it with a fine silk cloth and leave the filtrate. Place the filtrate in an open container and dry it in the sun to allow the water to gradually steam, or you can get a crude product containing 3-aminobenzene.
However, the crude product is not pure and needs to be refined again. Dissolve the crude product with an alcohol liquid, such as the alcohol of rice wine, and heat it with a light fire to keep the impurities in the bottom. Pour out the clear liquid while it is hot. When the clear liquid cools, or crystals precipitate, this may be a purer 3-aminobenzene.
Although this is based on the ancient idea, it is different from the modern chemical precision method, but it also follows the path of the ancient people's use of natural things and simple processes for transformation for discussion.
What are the precautions for storing and transporting 1-fluoro-3-nitrobenzene?
In the process of storage, oxygen, and aminobenzene should be paid attention to.

If it is not flammable and explosive, it can be ignited to a low level, and it can be mixed in air to form an explosive mixture. Therefore, if it is not stored, it must be well-connected, and the source of ignition and the source of ignition must be good. The container should also be firmly sealed to prevent leakage. On the way, it is also necessary to follow the relevant methods, and it is suitable for use, and it should be sent by people to ensure safety.
Oxygen is not a flammable material, but it is a combustion aid. If it is stored, it should not be stored in a room with flammable and combustible materials to prevent open flames or high-temperature fires. Containers should also be properly inspected regularly for leakage. It is also necessary to pay attention to isolation, avoid the mixing of flammable and explosive materials, and ensure the safety of its environment.
Aminobenzene is a toxic and harmful chemical substance. It should be stored in the room where it is used, and the source of fire. And it should be stored in equal parts of oxidation and acid, and should not be mixed. Because of its toxicity, it is necessary to store all confidential preventive measures to avoid human contact or inhalation. If it is not necessary, it is necessary to abide by the seal of hazardous chemicals. The package must comply with the relevant standards to prevent leakage and pollution of the environment. It is also necessary to ensure the safety of people and avoid the occurrence of accidents such as poisoning.
The three properties are different, and the existence or damage are all based on their characteristics. Prevention and control must not be slack a little to ensure the safety of the process.
What are the effects of 1-fluoro-3-nitrobenzene on the environment and human health?
"Tiangong Kaiwu" states: "Grain is called
in the south, and
in the north, it is called millet, which is the length of the five grains. Its species are different, there are japonica and waxy, there are early crops and late crops. The soil of rice is suitable, if you get water, you will live, and if you don't have water, you will die. Where the veins of rice are scorched and withered, the ears will be desolate." The growth of rice is closely related to the environment. Water is also the lifeblood of rice. The amount and turbidity of water are all related to the rise and fall of rice.
As for glutamine, it is an extremely important amino acid in the human body. It has a wide range of functions in the human body. Under normal physiological conditions, glutamine participates in many metabolic processes, such as the synthesis of proteins and nucleic acids, providing
In terms of the immune system, glutamine is very powerful. When the human body encounters stress such as disease and trauma, the immune system load increases. At this time, glutamine can help the proliferation and function of immune cells, enhance the body's ability to resist external evil, fill the defense qi, and prevent evil from drying.
Furthermore, glutamine also has an important impact on intestinal health. The growth and repair of intestinal mucosal cells rely on glutamine as an energy substance. If glutamine is deficient, the intestinal mucosal barrier function is damaged, just like the collapse of the city wall, and external evil is easy to invade, causing intestinal diseases to multiply. Therefore, glutamine is of great significance in maintaining the integrity of the intestinal mucosa and preventing the translocation of intestinal bacteria, which is an important safeguard for human health.