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Benzene, 1-Fluoro-3-Methyl-5-Nitro-

Benzene, 1-Fluoro-3-Methyl-5-Nitro-

Hongda Chemical

Specifications

HS Code

142128

Chemical Formula C7H6FNO2
Molecular Weight 155.13
Appearance Solid (predicted)
Boiling Point Estimated around 240 - 260 °C
Melting Point Estimated range: 50 - 70 °C
Density Approx. 1.3 - 1.4 g/cm³ (estimated)
Solubility In Water Low solubility, likely sparingly soluble
Vapor Pressure Low vapor pressure at room temperature
Flash Point Estimated around 100 - 120 °C
Odor May have a characteristic, possibly pungent odor

As an accredited Benzene, 1-Fluoro-3-Methyl-5-Nitro- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100 - gram vial packaging for 1 - fluoro - 3 - methyl - 5 - nitro - benzene chemical.
Storage 1 - fluoro - 3 - methyl - 5 - nitro - benzene should be stored in a cool, well - ventilated area, away from heat, sparks, and open flames as it is likely flammable. Keep it in a tightly sealed container to prevent vapor release. Store it separately from oxidizing agents, reducing agents, and reactive chemicals to avoid potential hazardous reactions. Ensure proper labeling for easy identification and handling.
Shipping 1 - fluoro - 3 - methyl - 5 - nitro - benzene, a chemical, is shipped in specialized containers. These are designed to prevent leakage, meet safety regulations, and ensure secure transport due to its potentially hazardous nature.
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Benzene, 1-Fluoro-3-Methyl-5-Nitro- Benzene, 1-Fluoro-3-Methyl-5-Nitro-
General Information
Historical Development
Guanfu Benzene, 1 - Fluoro - 3 - Methyl - 5 - Nitro - The historical evolution of this object is quite instructive. In the past, the Fang family began to explore the secrets of chemistry and continued to study all kinds of substances. At the beginning, the details of this object were not obtained. After years of study, the technology gradually refined, and then it was obtained. At that time, the instrument was not refined, and the road to exploration was difficult. However, scholars were unswerving, and after countless tests, their structural characteristics were finally clarified. With the passage of time, technological innovation and preparation methods have also become more perfect. From the initial difficult search to today's precise control, the progress during this period depends on the efforts of scholars of all dynasties. The historical development of this compound is like a long river rushing forward, witnessing the prosperity of chemistry.
Product Overview
Product Overview
Today there is a product named "1-fluoro-3-methyl-5-nitrobenzene". This is an organic compound with an extraordinary status in the chemical industry.
Looking at its structure, on the benzene ring, fluorine atoms, methyl groups and nitro groups are on each side, giving it unique chemical properties. It has certain reactivity, or participates in nucleophilic substitution, nitrification and other reactions, and is a key raw material for organic synthesis.
From the perspective of use, it can be used as a pharmaceutical, pesticide and dye intermediate. In pharmaceutical research and development, it helps to create new drugs; in pesticide production, it contributes to the synthesis of high-efficiency and low-toxicity pesticides; in dye manufacturing, it can give dyes unique color and performance.
However, this substance also has latent risk, because it contains nitro groups, or has certain toxicity and explosiveness. When operating, strict regulations must be followed to ensure safety. In summary, although "1-fluoro-3-methyl-5-nitrobenzene" is dangerous, rational use can contribute a lot to the development of chemical industry.
Physical & Chemical Properties
A chemical researcher studies the physicochemical properties of 1-fluoro-3-methyl-5-nitrobenzene. This compound may appear as a colorless to light yellow liquid with a special odor. Its boiling point is about a certain range, and its melting point also has a specific value, which is related to the intermolecular force and structure.
When it comes to solubility, it may have a certain solubility in organic solvents. Due to the similar principle of miscibility, its molecular structure is partially compatible with that of organic solvents. And its density is higher or smaller than that of water, which affects its sinking and floating in water.
And because it contains fluorine, methyl, nitro and other groups, it is chemically active. Nitro groups have strong oxidizing properties, methyl groups affect the distribution of electron clouds, and fluorine atoms have high electronegativity, which makes this compound exhibit unique properties in chemical reactions, or can participate in many reactions such as substitution and addition, which is of great research value in the field of organic synthesis.
Technical Specifications & Labeling
Today there is a product named "Benzene, 1 - Fluoro - 3 - Methyl - 5 - Nitro -". The study of process specifications and identification (product parameters) is the priority of our chemical researchers.
Looking at this substance, its molecular structure is unique, and fluorine, methyl, and nitro are arranged in specific positions in the benzene ring. This structure is related to its physical and chemical properties. In the process specifications, the synthesis method needs to be precisely controlled, and the ratio of raw materials and reaction conditions are all key. The choice of temperature, pressure, and catalyst has a slight difference, and the product is impure or the yield is low.
On the label, its characteristics, hazards and protection are clearly stated. This substance may be toxic and corrosive, and the label should be clearly warned. Product parameters should be detailed in purity, impurity content, etc., to help users understand its quality. In this way, only in production and application can this substance be safely and efficiently controlled, and live up to the mission of chemical research.
Preparation Method
Benzene, 1 - Fluoro - 3 - Methyl - 5 - Nitro - is prepared in this product. Fluoride, methylating agent, nitrifying agent, etc. are taken as raw materials. The process of its preparation is first to make benzene and methylating agent co-react, according to appropriate temperature and pressure, and control its reaction to obtain 3 - methylbenzene. Then, under the conditions that 3 - methylbenzene and fluoride meet and adjust, 1 - fluoro - 3 - methylbenzene is produced. Finally, let 1-fluoro-3-methylbenzene and nitrifying agent meet, observe the reaction process, prevent its overreaction, and obtain Benzene, 1-Fluoro-3-Methyl-5-Nitro -. In this whole process, the rate of reaction is controlled, depending on the catalytic mechanism, the appropriate catalyst is selected to increase its efficiency, so that the yield is increased and the purity of the product is guaranteed. In this way, the preparation of this substance can be achieved.
Chemical Reactions & Modifications
The chemical substance, the change of thousands, reaction and modification, is the gist of research. Today there is "Benzene, 1 - Fluoro - 3 - Methyl - 5 - Nitro -", and the study of its chemical reaction is crucial.
In the reaction, fluorine, methyl, nitro and other groups interact to affect the properties of molecules. The introduction of fluorine can change the polarity and reactivity of molecules; methyl may affect the spatial resistance and electron cloud distribution; nitro is often a strong electron-absorbing group, which changes the density of benzene ring electron clouds and causes reactivity to be different.
To clarify its modification, when studying the reaction conditions, such as temperature, catalyst, etc. Temperature change, can speed or slow reaction; catalyst can reduce the activation energy, promote the initiation of the reaction. After various explorations, the phase can control its reaction law, resulting in the optimization of the performance of this material, in the chemical industry, medicine and other fields, it is widely used and beneficial.
Synonyms & Product Names
Today there is a thing called 1-fluoro-3-methyl-5-nitrobenzene, which is also known as another name. This chemical thing is quite important in our research.
The names of all things in the world are often not unique. 1-fluoro-3-methyl-5-nitrobenzene, or has other names to meet different situations and different uses. Just like the ancients called things, they changed their names from time to time and place to place.
This chemical product, in various fields of chemical industry, or due to the convenience of operation and the different uses, has different names, just like the names of ancient things, with proper names and common names. Those of us who are learners, when we know its many titles, can study it without confusion, use it freely, and navigate freely in the mysterious realm of chemistry, exploring its subtleties and achieving its wonders.
Safety & Operational Standards
"About 1-fluoro-3-methyl-5-nitrobenzene product safety and operating specifications"
Fu 1-fluoro-3-methyl-5-nitrobenzene, chemical substances are also. In the experiment and production, safety and operating standards are of paramount importance.
The first word is safety. This substance is dangerous to a certain extent, or there is a risk of ignition and explosion, or it may hurt the human body. Therefore, when storing, it is necessary to choose a cool, dry and well-ventilated place, away from fire and heat sources. Packaging must be tight to prevent leakage. When taking it, be prepared with protective equipment, such as gloves, goggles, gas masks, etc., to ensure your own safety.
The second discussion on the operating specifications. Experimenters must first familiarize themselves with its properties and understand the rationale of their reactions. In the operation room, the instruments must be clean and intact, and they must be done in sequence without disorder. When mixing materials, add them slowly to check their reaction state. If there is any abnormality, take countermeasures quickly. After the reaction is completed, the products and wastes should be treated in accordance with the regulations and should not be discarded at will to avoid polluting the environment.
In short, the safety and operating standards of 1-fluoro-3-methyl-5-nitrobenzene are related to human life and the environment. All practitioners should observe them carefully and not slack off, so as to ensure that everything goes smoothly and is safe.
Application Area
1-Fluoro-3-methyl-5-nitrobenzene (Benzene, 1-Fluoro-3-Methyl-5-Nitro -) This compound is widely used in many fields. In the development of medicine, its unique chemical structure may participate in the construction of specific drug molecules to help develop specific drugs for certain diseases. In the field of materials science, it can be chemically modified to give materials unique electrical and optical properties, such as for the manufacture of new optoelectronic materials to improve device performance. In the field of agriculture, it may be used as a raw material to synthesize new pesticides. With its chemical activity, it can achieve high-efficiency insect control and disease resistance, and ensure the harvest of crops. From this point of view, 1-fluoro-3-methyl-5-nitrobenzene has broad application prospects in many fields, and it is worth further investigation to explore its potential value.
Research & Development
About the research and development of 1-fluoro-3-methyl-5-nitrobenzene
Wutao is committed to the research of 1-fluoro-3-methyl-5-nitrobenzene. This compound has a unique structure and unique properties, and has great potential in various fields of chemical industry.
The first time involved in its field, the synthesis method was studied in detail. After several attempts, refer to the classics, improve the existing method, and strive for efficient and pure synthesis. The reaction conditions, such as temperature, pressure, and catalyst dosage, are carefully investigated to ensure a smooth reaction and excellent yield.
Then its physicochemical properties are observed. Measure its melting point and solubility, and clarify its stability in different mediums. Also explore its chemical activity, and know that it can interact with a variety of reagents to lay the foundation for the derivation of new compounds.
As for the development trend, look forward to its application in medicine and materials. It is expected that after modification and transformation, it may become a special drug; in the material industry, or give new properties to materials. I will make unremitting research, hoping to expand its use, and do my best for the prosperity of the chemical industry.
Toxicity Research
The industry of chemical industry is related to people's livelihood, but the investigation of toxicants in it cannot be ignored. Today there is a product name "Benzene, 1 - Fluoro - 3 - Methyl - 5 - Nitro -", and the study of its toxicity is quite important.
This product also has fluorine, methyl, and nitro groups. Nitro groups are often highly oxidizing, or cause chemical changes, damaging biological tissues. Fluorine atoms are active, change the properties of molecules, and are toxic and bioactive. Although methyl is relatively stable, it also affects the overall physical properties.
To understand its toxicity, you should look at the way it enters the body, or through breathing, or through the skin, or through diet. After entering the body, it follows the bloodline and reaches the viscera, disturbing the order of biochemistry. It may hinder cell metabolism, or damage the gene structure, causing disease and change, which must be prevented. Therefore, in the context of its production and use, strict regulations must be set up to protect people in the future and maintain the peace of the environment. This is the heavy responsibility of our chemical researchers.
Future Prospects
In the field of Wuguan Chemical Industry, new products are emerging one after another. In the compound "Benzene, 1 - Fluoro - 3 - Methyl - 5 - Nitro -", its future prospects are quite profound. The properties of this material can be explored in the reaction mechanism, and if it is well studied, it may open up new paths for synthesis. In the creation of materials, it can be made into unique materials, which can be used in electronics and medicine. In medicine, it may be a targeted medicine for precise treatment; in electronics, it may be a key component to improve efficiency. In addition, if its mass production process is refined, the cost will be reduced, so that more fields can enjoy its benefits. Although the road ahead may encounter difficulties, researchers should have a determined heart and strive for the end, expecting to shine in the future, seek well-being for the world, and expand the New Territories of chemical industry.
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Frequently Asked Questions

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What are the chemical properties of 1-fluoro-3-methyl-5-nitrobenzene
This is an organic compound with complex properties. The compound contains 1-alkyne-3-methyl-5-chlorobenzene structure. The presence of alkynyl groups endows it with certain reactivity. The electron cloud density of carbon-carbon triple bonds in the alkyne bond is high, and it is prone to addition reactions. It can be added with many electrophilic reagents such as halogens and hydrogen halides to form various derivatives. As an alkyl group,
methyl has a electron-inducing effect, which can increase the electron cloud density of the benzene ring, making the benzene ring more prone to electrophilic substitution reactions. In reactions such as halogenation, nitrification, sulfonation, etc., the reactivity may increase slightly due to the presence of methyl groups, and the steric resistance of methyl groups also affects the selection of the reaction check point.
The chlorine group is connected to the benzene ring, which has an electron-sucking induction effect and a electron-donating conjugation effect. Under the interaction of the two, the electron cloud distribution of the benzene ring is affected. In the electrophilic substitution reaction, the chloro group is an ortho-and para-localization group, which makes the electrophilic reagent more inclined to At the same time, chlorine atoms can participate in the formation of hydrogen bonds and other intermolecular interactions, which affect the physical properties of compounds such as melting point, boiling point, solubility, etc.
This compound exhibits unique chemical properties due to the synergistic effect of alkynyl, methyl and chlorine groups, and may have important potential applications in organic synthesis, medicinal chemistry and other fields. It can be used as a key intermediate for the synthesis of more complex and functional organic molecules.
What are the main uses of 1-fluoro-3-methyl-5-nitrobenzene?
1 + -Jiang-3-methyl-5-nitrobenzene This substance is called 1-methyl-3-nitro-5-ethylbenzene, and its main uses are as follows:
First, in the field of organic synthesis, it is a key intermediate. For example, when preparing complex drug molecules, other functional groups can be introduced into its benzene ring through specific reactions to construct compounds with specific physiological activities. In the process of synthesizing some antibacterial drugs, 1-methyl-3-nitro-5-ethylbenzene is used as the starting material, and the nitro group is reduced to amino group, and then condensed with other compounds containing active groups, so as to obtain drugs with antibacterial effect.
Second, as an important raw material for dye synthesis. Because the methyl, nitro and ethyl groups on the benzene ring can participate in various coupling reactions, diazotization reactions, etc., giving the dye unique color and stability. For example, in the synthesis of yellow series disperse dyes, the use of 1-methyl-3-nitro-5-ethylbenzene for structural modification can make the dyes exhibit good dyeing properties and color fastness on different fiber materials.
Third, it also has applications in materials science. After functional modification, it can be used to prepare polymer materials with special properties. For example, copolymerization with monomers with conjugated structures can improve the electrical properties of materials and be used to make organic semiconductor materials, which play a role in devices such as organic Light Emitting Diodes (OLEDs) and organic field effect transistors (OFETs).
What are the synthesis methods of 1-fluoro-3-methyl-5-nitrobenzene
To prepare 1-alkyne-3-methyl-5-carbonylhexene, the following method can be used:
First, a suitable alkyne is used as the starting material. If acetylene is selected, it is first reacted with a strong base, such as sodium amide ($NaNH_2 $), to form sodium acetylene. This reaction is due to the strong alkalinity of sodium amide, which captures the hydrogen acetylene from the acetylene and makes the alkyne into a negative alkyne ion, which has strong nucleophilicity.
Then, the sodium acetylene is reacted with a halogenated hydrocarbon containing a suitable substituent. If 1-chloro-2-methyl-4-carbonyl butane is selected, the alkyne anion nucleophilic attacks the α-carbon of the halogenated hydrocarbon, the halogen ion leaves, and a carbon-carbon bond is formed to obtain the precursor of 1-alkyne-3-methyl-5-carbonylhexene. This is the nucleophilic substitution reaction mechanism, and the α-carbon of the halogenated hydrocarbon is partially positive and vulnerable to attack by nucleophilic reagents.
Another way is to first construct the carbon chain where the carbonyl group and the methyl group are located. For example, using ethyl acetoacetate as a raw material, using its active methylene, first interacts with a base to generate carbonegative ions. This anion is reacted with a suitable halogenated olefin, such as 3-chloro-1-butene, through nucleophilic substitution, the alkenyl group is introduced. Subsequently, a series of reactions such as decarboxylation of the ethyl acetoacetate part are carried out to adjust the position of the carbonyl group and related structures, and the final product is 1-alkynyl-3-methyl-5-carbonylhexene. The decarboxylation reaction usually requires heating and other conditions to rearrange the ethyl acetoacetate structure, lose carbon dioxide, and form one part of the target structure.
Or, using diethyl malonate as the starting material, using the carbon anion formed by the reaction with the base, and reacting with the halogenated hydrocarbon containing alkynyl groups and suitable substituents, the carbon chain is gradually constructed. Subsequent steps such as hydrolysis and decarboxylation are also expected to obtain the target product. The hydrolysis step can convert the ester group to a carboxyl group, and the decarboxylation step further adjusts the structure to achieve the synthesis of 1-alkynyl-3-methyl-5-carbonylhexene.
What are the precautions for 1-fluoro-3-methyl-5-nitrobenzene during storage and transportation?
1 + -Jiang-3-methyl-5-chlorobenzene must pay attention to many matters during storage and transportation.
This compound contains chlorine groups, which are toxic and corrosive to a certain extent. When storing, be sure to choose a dry, cool and well-ventilated place to prevent moisture and high temperature from causing it to deteriorate or cause dangerous reactions. It should be placed separately from flammable, explosive and oxidizing substances to avoid safety accidents caused by improper mixing.
When transporting, it is necessary to strictly comply with relevant regulations and standards, and use special packaging materials to ensure that the packaging is tight and there is no risk of leakage. The means of transportation also need to be clean, dry, and have corresponding protective measures to prevent external factors from affecting the stability of the compound. Transportation personnel should be familiar with the characteristics of the compound and emergency treatment methods, and can respond quickly and properly in the event of leakage and other situations.
Furthermore, whether it is storage or transportation, detailed records need to be established, covering the source, quantity, storage and transportation conditions, warehousing and other information for traceability and management. Personnel operating this compound need to be professionally trained, proficient in correct operation procedures and safety precautions, and equipped with appropriate protective equipment, such as protective clothing, gloves, goggles, etc., to ensure their own safety.
What are the effects of 1-fluoro-3-methyl-5-nitrobenzene on the environment and human health?
Fu 3-methyl-5-carboxylpyridine has an impact on the environment and human health, which cannot be ignored.
First of all, discuss its impact on the environment. If this substance is released in nature, it may cause water pollution. When it enters the water body, it may react with various substances in the water to change its chemical properties. And this substance may be difficult to degrade, accumulate in the water body for a long time, endangering aquatic organisms. Such as plankton, sensitive to environmental changes, the existence of 3-methyl-5-carboxylpyridine may disrupt its normal metabolism, causing population changes, and then disturbing the balance of aquatic ecological chains. And in the soil, if it penetrates, or changes the soil pH and nutrient structure, it will hinder the absorption of nutrients by plant roots, causing plant growth to be inhibited, or it may be stunted.
As for the impact on human health, it should not be underestimated. If people ingest it through breathing, diet or skin contact, it may endanger their health. In the respiratory system, or irritate the mucosa of the respiratory tract, causing cough, asthma, breathing difficulties, especially in people with asthma or sensitive respiratory tract, it is even more harmful. Enter the digestive system, or damage the gastrointestinal mucosa, causing nausea, vomiting, abdominal pain and other discomfort. And this substance may be potentially carcinogenic, long-term exposure may increase the risk of cancer. Due to its special chemical structure, or interfering with the human endocrine system, disrupting the balance of hormones, causing abnormalities such as reproduction and development.
Therefore, the use and discharge of 3-methyl-5-carboxypyridine should be handled with caution, and proper management and handling methods must be taken to reduce its harm to the environment and human health.