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Benzene, 1-Fluoro-2-(Methylsulfonyl)-

Benzene, 1-Fluoro-2-(Methylsulfonyl)-

Hongda Chemical

Specifications

HS Code

350105

Chemical Formula C7H7FO2S
Molecular Weight 174.192 g/mol

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Packing & Storage
Packing 100 - gram vial for 1 - fluoro - 2 - (methylsulfonyl) benzene chemical packaging.
Storage Store “Benzene, 1 - fluoro - 2 - (methylsulfonyl)-” in a cool, dry, well - ventilated area, away from heat sources and open flames due to its potential flammability. Keep it in a tightly closed container, preferably made of corrosion - resistant materials, to prevent leakage and exposure to air or moisture which could trigger unwanted reactions. Segregate from incompatible substances like oxidizing agents.
Shipping Benzene, 1 - fluoro - 2 - (methylsulfonyl)- is a chemical. Shipping should follow strict hazardous materials regulations. It must be properly packaged, labeled, and transported by carriers licensed for such chemicals to ensure safety.
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Benzene, 1-Fluoro-2-(Methylsulfonyl)- Benzene, 1-Fluoro-2-(Methylsulfonyl)-
General Information
Historical Development
Taste the industry of chemical industry, study the changes of substances, and change with each passing day. Today there is a thing called "Benzene, 1 - Fluoro - 2 - (Methylsulfonyl) -", and the research of its things can also be followed.
At the beginning, the craftsmen did not know its nature, and they were lost in exploration. Over the years, the wise men have devoted themselves to thinking, analyzing its structure, exploring its reaction. Or in the secret room, the lamp is burning at night; or on the paperwork, thinking hard about it.
Gradually understand how it can be obtained and where it is stable. What was unknown in the past has now been seen. Its journey, if you go against the current, you can move forward with perseverance. From ignorance and clarity, the research and development of this substance has witnessed the wisdom of all the sages, and has also added a chapter to the history of chemical industry. Future generations should follow their ambitions and explore the unknown.
Product Overview
A chemical substance, called 1-fluoro-2- (methylsulfonyl) benzene. Its form or colorless liquid, with a special odor. This substance is widely used in the field of organic synthesis.
Structurally, on the benzene ring, fluorine atoms and methyl sulfonyl groups each have one position, which affects each other, resulting in its unique properties. Because of its fluorine content, it has a certain electronegativity and can change molecular polarity; the presence of methyl sulfonyl groups adds reactivity.
In the reaction, it is often used as a key intermediate. It can be prepared by multiple methods, such as starting with a specific halogenated benzene and obtaining it through several steps of reaction. Its stability is also affected by the surrounding environment, temperature, humidity, light, etc., can cause its changes. Therefore, when storing and using, follow the rules to prevent its deterioration to ensure efficacy and safety.
Physical & Chemical Properties
1-Fluoro-2 - (methylsulfonyl) benzene, the physical and chemical properties of this compound are related to the gist of our chemical research. Its appearance or specific color and shape are related to the intuitive characteristics of the substance. Thermodynamic parameters such as boiling point and melting point reflect the strength of intermolecular forces and are crucial in the separation and purification process. In terms of solubility, the performance of various solvents determines its dispersion and participation in the reaction system. Its chemical activity is unique due to the existence of fluorine atoms and methylsulfonyl groups. Fluorine atoms have strong electronegativity, which can affect the distribution of electron clouds in the benzene ring. Methylsulfonyl groups also have electronic effects and spatial effects. The synergy of the two makes the compound exhibit specific activities in nucleophilic and electrophilic reactions. The study of its physical and chemical properties is the cornerstone of in-depth understanding of the reaction mechanism and optimization of the synthesis path, and is indispensable for the development of the chemical field.
Technical Specifications & Labeling
There is now a process for making 1-fluoro-2- (methylsulfonyl) benzene, and its process specifications and identification (product parameters) are the key. To make this product, the amount of various materials should be known in advance, and the formula should be precise. In the reaction device, control it to a suitable temperature and keep it at an appropriate time to ensure a smooth reaction.
After the reaction is completed, the properties of the product should be carefully reviewed. Looking at its color, it should be pure and free of impurities; measuring its quality, it must meet the established standards. On the label, the chemical properties, uses, and attentions of this product are recorded in detail, so that the user can see it at a glance, and there is no risk of misuse. The process specification is rigorous, and the identification is clear and correct, so that high-quality 1-fluoro-2- (methyl sulfonyl) benzene can be obtained to meet all requirements.
Preparation Method
To prepare 1-fluoro-2 - (methylsulfonyl) benzene, the method is as follows:
The raw material needs to be prepared with benzene-containing compounds, fluorinated reagents, methylsulfonylation reagents, etc.
At the beginning of the reaction, the benzene-containing compound is interacted with the fluorinated reagent under suitable conditions. In this step, the temperature and time need to be controlled to make the fluorine atom just fit into the specific position of the benzene ring.
Then, the methyl sulfonyl group is introduced, and the fluorinated product is reacted with the methylsulfonylation reagent in a specific environment. Pay attention to the choice of reaction solvent and catalyst.
During the reaction process, monitoring means are often used to check the progress. If there is any deviation, adjust it After the reaction is completed, the impurities are removed by separation and purification to obtain pure 1-fluoro-2 - (methylsulfonyl) benzene. This process, the control of the reaction conditions at each step, and the quality and quantity of the product, all need to be done with caution.
Chemical Reactions & Modifications
There is now a chemical substance, named "Benzene, 1 - Fluoro - 2 - (Methylsulfonyl) -". In chemical research, its reaction and modification are worth exploring.
Looking at the reaction, under different conditions, it should be different. In the event of a reagent, the change of nucleophilic substitution occurs, and the fluorine atom is replaced by another group. This change is related to the temperature, pressure and medium of the reaction. If the temperature is high, the pressure is suitable and the medium is suitable, the reaction is fast and effective.
As for modification, new groups can be introduced to adjust its physicochemical properties. Such as adding a nitrogen-containing group, or changing its polarity and solubility to suit different needs. It can also be changed by the change of structure to change its stable state and make it more secure in a specific environment. This is the way for chemists to seek innovation and change, hoping to explore more possibilities of this thing with exquisite methods and contribute to the progress of chemistry.
Synonyms & Product Names
"Benzene, 1 - Fluoro - 2 - (Methylsulfonyl) -" This product, its synonym and trade name, is the key to chemical research. The name of a chemical substance often has many titles due to its use and discovery process. For this compound, in academia or industry, synonyms can help researchers communicate accurately, and trade names are convenient for market circulation.
The subtlety of chemistry lies in the precise naming of substances. Synonyms such as aliases describe their properties from different angles. Trade names are designed to meet commercial needs, giving them easy-to-remember and representative names. Studying this "Benzene, 1 - Fluoro - 2 - (Methylsulfonyl) -" will clarify its synonyms and trade names, which will help to gain a deeper understanding of its applications in different fields, and provide convenience for scientific research and industrial production, so as to achieve accurate cognition and efficient application.
Safety & Operational Standards
1-Fluoro-2 - (methylsulfonyl) benzene is an important substance in chemical research. Safety and operating standards are of paramount importance during its research and use.
The first word is safety. This substance has certain chemical activity or potential harm to the human body and the environment. Therefore, researchers need to prepare comprehensive protective measures. In the experimental site, it is necessary to ensure good ventilation to prevent the accumulation of harmful gases. Operators should wear appropriate protective clothing, such as laboratory clothes, gloves, and protective glasses to avoid direct contact with the skin and eyes. In case of inadvertent contact, rinse with plenty of water immediately and seek medical treatment according to the specific situation.
Second discussion on operating specifications. When taking 1-fluoro-2 - (methylsulfonyl) benzene, it is necessary to follow accurate measuring procedures. The measuring equipment should be clean and accurate to ensure the reliability of the experimental data. During the reaction process, the reaction conditions such as temperature and pressure must be strictly controlled. Because the reactivity of the substance is quite sensitive to environmental factors, it is slightly poor, or the reaction may be out of control and cause danger. And the waste after the reaction should not be discarded at will. It should be properly disposed of in accordance with relevant environmental regulations to prevent pollution to the environment.
Furthermore, storage should also be cautious. 1-Fluoro-2- (methylsulfonyl) benzene should be stored in a cool, dry and ventilated place, away from sources of ignition and oxidants. Storage containers must be well sealed to prevent leakage. Periodically check the storage environment and containers to ensure safety.
In short, the whole process of research and operation of 1-fluoro-2- (methylsulfonyl) benzene should strictly observe safety and operating practices, so as to ensure the safety of researchers, promote the smooth progress of research, and protect the tranquility of the environment.
Application Area
Today, there is a product called 1-fluoro-2 - (methylsulfonyl) benzene. In the course of my chemical research, this product has a wide range of uses.
It can be used as a key intermediate in the field of pharmaceutical synthesis. With its unique structure, it can skillfully introduce specific groups to help create novel and efficient drugs, which is expected to cure diseases and benefit the common people.
In the field of materials science, it also has extraordinary performance. It can optimize material properties, or increase its stability, or add its functionality through specific reactions, making the material suitable for a variety of scenarios, such as advanced electronic devices, high-performance composites, etc., to promote the development of related fields.
This 1 -fluoro-2 - (methylsulfonyl) benzene has potential in many application fields, waiting for us to study further and explore more functions for the world.
Research & Development
The current research on this substance is called "Benzene, 1 - Fluoro - 2 - (Methylsulfonyl) -". I dedicated myself to exploring its properties. The structure of this substance is unique or has specific chemical properties.
I have tried different methods to understand its reaction mechanism. After many experiments, I know that it can react with a reagent under specific conditions to generate new substances. This reaction may be beneficial for its application expansion.
Although the research process encountered many obstacles, such as difficult to control the reaction conditions and impure products, etc. However, I was not discouraged and continued to adjust the plan. Looking to the future, if we can deeply understand its properties and reaction laws, we will be able to promote the application of this chemical in the fields of medicine, materials, etc., realize its leap from research to practical application, and contribute to the development of science.
Toxicity Research
Study on the toxicity of 1-fluoro-2 - (methylsulfonyl) benzene
If you want to study the toxicity of 1-fluoro-2 - (methylsulfonyl) benzene (Benzene, 1-Fluoro-2 - (Methylsulfonyl) -), it is necessary to investigate its physicochemical properties in detail, and conduct experiments to understand its impact on life and all things.
First look at its structure, fluorine and methylsulfonyl are attached to the benzene ring, or cause it to have special reactivity. Take animals as models and feed them with food containing this substance to observe its physiological changes. It may disturb the metabolism of animals and damage their liver and kidney. At the cellular level, this substance may break the stability of the cell membrane and disrupt the signal transduction in the cell.
It also examines its behavior in the environment. If this substance enters the water or soil, it may be harmful to the ecology. Or it accumulates in the organism through the food chain, harming the higher-level organisms. Therefore, in the aspects of its production and use, strict prevention and control should be carried out, and toxicity should be studied in detail to ensure the safety of all living beings and the balance of ecology.
Future Prospects
Looking at the world, science and technology are improving day by day, and in the field of chemistry, there are also many achievements. Today, I am talking about 1-fluoro-2- (methylsulfonyl) benzene. Its potential in the chemical industry is extraordinary.
The future prospect lies in the application and innovation. In pharmaceutical research and development, it may be the basis for new agents, and with its unique structure, it can find a wonderful way to cure diseases and save people. In materials science, it may help the birth of new materials, increase their performance, and expand their uses.
Furthermore, the method of synthesis also needs to be refined. We should seek a simpler, more efficient, and more environmentally friendly way to reduce energy consumption and pollution, which is suitable for sustainable development. Over time, 1-fluoro-2 - (methylsulfonyl) benzene will shine in various fields, contribute to human well-being, and become an important cornerstone of future chemical development.
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Frequently Asked Questions

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What are the chemical properties of 1-fluoro-2- (methylsulfonyl) benzene?
(Mono-methylaminoformyl) hydrazine, also known as (methylaminoformyl) hydrazine, has the following chemical properties:
This substance has a certain activity. From a structural point of view, the carbonyl group is connected to the amino group, and the carbonyl group has a certain electron-withdrawing property, while the nitrogen atom in the hydrazide group contains lone pairs of electrons, which makes the substance can participate in the reaction as a nucleophile in chemical reactions.
In the field of organic synthesis, due to its unique structure, it can participate in a variety of reactions to construct more complex organic compounds. For example, its hydrazine moiety can undergo condensation reactions with formaldehyde, ketone and other carbonyl compounds to form hydrazone derivatives. This kind of reaction is often used in organic synthesis to grow carbon chains, introduce specific functional groups, and construct nitrogen-containing heterocyclic compounds.
From the perspective of stability, this substance is relatively unstable. The presence of hydrazine groups makes it more sensitive to acid-base environments. Under acidic conditions, both the nitrogen atom of the aminoformyl group and the nitrogen atom of the hydrazine group may undergo protonation, which may affect the molecular structure and stability, and even trigger decomposition reactions. Under basic conditions, some nucleophilic substitutions or elimination of the hydrazine basic body may also occur, resulting in changes in the molecular structure.
At the same time, since the substance contains multiple nitrogen atoms, under appropriate conditions, oxidation reactions may occur, and the oxidation state of the nitrogen atoms will change, thereby changing the properties and structure of the entire compound. Moreover, this oxidation process may occur more easily in the presence of some oxidizing agents, so care should be taken to avoid contact with strong oxidizing agents during storage and use.
What are the physical properties of 1-fluoro-2 - (methylsulfonyl) benzene?
(Ethyl methanesulfonate) of B, its physical properties are as follows:
Under normal conditions, it is usually transparent in color and has a weak ether aroma. Its melting temperature is low, at -75 ° C, so it can also maintain liquid temperature in low temperature environments. And its boiling phase is high, 118-119 ° C, which makes it difficult to disperse under normal addition conditions.
The density of B is slightly larger than that of water, 1.104-1.110 g/cm ³, if mixed with its water, it will sink underwater. Its solubility is also special, and it can be miscible in ethanol, ether, acetone, etc., indicating that it has good miscibility in the soluble system; however, its solubility in water is limited, and it is slightly soluble in water.
In addition, the solubility of B is small, and it is placed in regular open areas, and the speed is slow. Its quality is acceptable under normal conditions, but in case of open fire, high temperature or oxidation, it is dangerous to cause combustion and explosion. And this material has certain toxicity, and it has irritating effects on human skin, eyes and respiratory tract. Special attention should be paid to safety precautions when using it. In addition, it is very important to understand the physical properties of B, which is essential for its proper use and prevention.
What are the common synthesis methods for 1-fluoro-2 - (methylsulfonyl) benzene?
The common synthesis of (methyl orange) hydrazine is obtained by the reaction of sodium nitrite and hydrazine sulfate at low temperature. In this reaction, hydrazine sulfate first interacts with sodium nitrite and undergoes a series of chemical changes to form (methyl orange) hydrazine.
To perform this synthesis, prepare an appropriate amount of hydrazine sulfate and sodium nitrite, and dissolve the hydrazine sulfate into a suitable solvent, usually water, to form a uniform solution. Sodium nitrite is also dissolved in the same way. Then, in a low temperature environment, usually at 0-5 degrees Celsius, slowly drop the sodium nitrite solution into the hydrazine sulfate solution, and stir at the same time to allow the two to fully contact the reaction. After adding the drops, keep stirring at low temperature for a while to make the reaction complete. At the end of the reaction, the pure (methyl orange-based) hydrazine product can be obtained by separation and purification methods, such as filtration, crystallization, recrystallization, etc.
This synthesis method requires low temperature operation. Due to high temperature, the reaction may go out of control, causing side reactions to produce, reducing the purity and yield of the product. And the drip rate also needs to be paid attention to. If it is too fast, the local reaction will be violent, which will be detrimental to the formation of the product. If it is too slow, it will take a long time and affect the efficiency. In addition, the purity of the reagent used and the cleanliness of the reaction vessel will all affect the synthesis results. When the experiment is carefully controlled, satisfactory results can be obtained.
In which fields is 1-fluoro-2 - (methylsulfonyl) benzene used?
(Methylaminoacetonitrile) (methylcyanomethylamine) is used in many fields. In the field of medicine, it is a key intermediate for the synthesis of many drugs. For example, in the preparation of some nervous system drugs, it plays an indispensable role. It can build the core structure of drug molecules through specific chemical reactions, laying the foundation for the development of drugs for the treatment of nervous system diseases such as anxiety and depression.
In the field of pesticides, it can be used as an important raw material for the synthesis of high-efficiency and low-toxicity pesticides. Through chemical transformation, compounds with unique insecticidal, bactericidal or herbicidal activities are generated, which can help develop green and environmentally friendly pesticides, which can not only effectively control crop diseases and insect pests, but also reduce environmental pollution and harm to non-target organisms.
In the field of organic synthesis, due to its special chemical structure, rich in reactive groups, it can participate in diverse organic reactions. For example, nucleophilic substitution reactions, addition reactions, etc., thereby constructing complex organic molecular structures, providing the possibility for the synthesis of organic materials with specific functions, such as photoelectric materials, etc., showing great potential in materials science research. In chemical production, it is also an important starting material for the preparation of a variety of fine chemicals, promoting the diversified development of the chemical industry.
What is the market outlook for 1-fluoro-2 - (methylsulfonyl) benzene?
The market prospect of Guanfu "1 + - + Jiang-2 - (methyl-hydroxymethyl) benzene" is really a matter of importance to many parties. This substance may have unique applications in the chemical industry.
The group of methyl-hydroxymethyl gives this benzene compound different chemical properties. In the field of organic synthesis, it may be a key intermediate. Due to the characteristics of methyl and hydroxymethyl, the reaction paths can be more diverse.
When it comes to market demand, first, in the process of pharmaceutical research and development, the synthesis of some special drugs may require this as a raw material. Today's pharmaceutical industry is booming, and there is a growing demand for novel and efficient synthetic raw materials. If this "1 + - + Jiang-2 - (methyl-hydroxymethyl) benzene" can meet the specific needs of drug synthesis, it will be able to occupy a place in the pharmaceutical raw material market.
Second, in the field of materials science, with the continuous emergence of new materials, the demand for organic compounds with special structures is also increasing. The unique structure of benzene substances may be used to prepare polymer materials and electronic materials with excellent performance. For example, in electronic packaging materials, its special chemical properties may enhance the stability and functionality of the material.
However, there are also many factors that need to be considered that affect its market prospects. The first one is the difficulty and cost of the synthesis process. If the synthesis of this substance requires cumbersome steps, high raw materials and harsh reaction conditions, it will inevitably push up its production costs and weaken market competitiveness.
Furthermore, regulations and policies restrict and regulate chemical products. Environmental protection requirements are increasingly stringent. If the production process of this substance has a greater impact on the environment and it is difficult to meet regulatory standards, its market expansion will also be full of thorns.
Overall, if "1 + - + Jiang-2 - (methyl hydroxymethyl) benzene" can overcome the problems of synthesis cost and environmental compliance, with its unique chemical structure in medicine and materials and other fields of potential applications, its market prospects may be quite promising; otherwise, it may face many challenges and the road to development will be bumpy.