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Benzene, 1-Fluoro-2,4-Dimethoxy-

Benzene, 1-Fluoro-2,4-Dimethoxy-

Hongda Chemical

Specifications

HS Code

748017

Chemical Formula C8H9FO2
Molecular Weight 156.154 g/mol
Physical State Solid (usually)
Appearance Colorless to pale - yellow solid
Boiling Point Approximately 244 - 246 °C
Melting Point 64 - 66 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone, dichloromethane
Odor Aromatic odor

As an accredited Benzene, 1-Fluoro-2,4-Dimethoxy- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1 - fluoro - 2,4 - dimethoxy - benzene packaged in a sealed chemical - grade bottle.
Storage 1 - fluoro - 2,4 - dimethoxybenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials like glass. Store it separately from oxidizing agents, strong acids, and bases to prevent potential chemical reactions. Label the storage clearly for easy identification and safety.
Shipping 1 - fluoro - 2,4 - dimethoxy - benzene is a chemical. Shipping should follow strict hazardous materials regulations. It must be properly packaged, labeled, and transported by carriers compliant with safety and environmental standards to prevent risks.
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Benzene, 1-Fluoro-2,4-Dimethoxy- Benzene, 1-Fluoro-2,4-Dimethoxy-
General Information
Historical Development
Benzene, 1 - Fluoro - 2,4 - Dimethoxy - This thing, its generation and evolution, can be developed. Trace its origin, the beginning, and the way to explore the transformation of materials, and move forward.
First, the research on the derivatives of human benzene has been in-depth. Its technology has not been as bright as it is today, but the determination of the monarch and the observation of the sensitivity have been revealed.
In the past month, those who have not developed methods to improve the method, and the characteristics of the substituent are reviewed. In this process, the exploration of the replacement of Fluoro Dimethoxy will be promoted.
Every time you get it, it is like a tower of sand, pushing this object into the unknown until the beginning, and then to clarify its characteristics and uses. This process is the light of the unremitting pursuit of truth in the world of transformation, and it is also the process of Benzene, 1 - Fluoro - 2,4 - Dimethoxy -.
Product Overview
A chemical is called "Benzene, 1 - Fluoro - 2,4 - Dimethoxy -", its substance is also, what is the shape? What is the property? This is what I have studied.
This substance has a unique structure. On the benzene ring, fluorine atoms and dimethoxy groups occupy specific positions. The benzene ring is the base of organic chemistry and has a stable conjugate structure. The fluorine atom is attached to it. Due to the strong electronegativity of fluorine, the distribution of molecular electron clouds can be changed, which affects its physicochemical properties. Dimethoxy groups also add characteristics, and methoxy groups are the power supply groups, which increase the density of electron clouds in the benzene ring.
Its properties may involve reactivity, solubility, etc. Extrapolated from the structure, or have special properties in electrophilic substitution reactions. The methoxy power supply makes the benzene ring rich in electrons, and the electrophilic reagents are easy to attack. Although the fluorine atom absorbs electrons, the resistance and the electronic effect work together, showing a unique reactivity. As for solubility, it contains polar methoxy groups or has a certain solubility in polar solvents.
Our researchers, when analyzing the physical properties and reactivity of this "Benzene, 1 - Fluoro - 2,4 - Dimethoxy -" in detail, add to the progress of chemistry.
Physical & Chemical Properties
1-Fluoro-2,4-dimethoxybenzene is also an organic compound. Its physical and chemical properties are worth studying.
Looking at its physical properties, it is in a liquid state at room temperature and has a special odor. Its boiling point, melting point, etc. are all elements that characterize its physical properties. The boiling point is related to its gasification temperature, and the melting point indicates the degree of solidification.
In terms of its chemical properties, it is unique in its activity due to the presence of fluorine, methoxy and other functional groups. Fluorine atoms have strong electronegativity, which can affect the distribution of electron clouds in molecules and change the reactivity of phenyl rings. Methoxy is a power supply radical, which can guide the orientation of the reaction in reactions such as electrophilic substitution. In the field of organic synthesis, or as a key intermediate, this compound participates in the construction of various complex structures and contributes significantly to the development of organic chemistry.
Technical Specifications & Labeling
F 1-fluoro-2,4-dimethoxy benzene is also an organic compound. To clarify its technical specifications and identification (product parameters), it should be reviewed in detail.
Looking at its chemical structure, fluorine atoms, dimethoxy groups are connected to benzene rings. This unique structure gives it specific physical and chemical properties. Regarding its technical specifications, the purity must reach a very high standard, and the impurity content must be strictly controlled. If there are too many impurities, it will affect its application in various fields.
As for the label, its chemical name, molecular formula, molecular weight and other key parameters should be clearly marked. This compound may have important uses in industrial synthesis, pharmaceutical research and development, etc. Precise technical specifications and clear labels are the basis for its safe and effective application. Do not be negligent, and strict laws must be followed to ensure its quality and safety of use.
Preparation Method
To prepare 1-fluoro-2,4-dimethoxybenzene (Benzene, 1-Fluoro-2,4-Dimethoxy -), the method is as follows:
Raw materials and production process: Pure phenols are selected, accompanied by an appropriate amount of halogenated reagents, and ethers are used as solvents. This is the choice of basic raw materials. Reaction steps: First dissolve phenols in ether, slowly add halogenated reagents, and control the temperature in a suitable range to fully react. During the reaction, it is necessary to stir it frequently to make the raw materials mix evenly and promote the reaction. Catalytic mechanism: The introduction of a specific catalyst can increase the reaction rate and reduce the energy required for the reaction. This catalyst can interact with raw materials to change the way of chemical reaction and achieve the purpose of efficient preparation. The 1-fluoro-2,4-dimethoxybenzene prepared by this method has passed the inspection and can be used for various subsequent uses.
Chemical Reactions & Modifications
A derivative of benzene, 1-fluoro-2,4-dimethoxy benzene, is under chemical change. The reaction of this substance is related to its molecular structure and functional group characteristics. The presence of fluorine atoms and methoxy groups makes it exhibit specific reactivity.
In many reactions, the methoxy gene has the property of electors, or affects the electron cloud density distribution of the benzene ring, which changes the adjacent and para-site activities of the benzene ring and guides the reaction direction. Although fluorine atoms have strong electronegativity, they can participate in reactions such as nucleophilic substitution under specific conditions, resulting in molecular structure remodeling.
To explore its chemical changes, various methods can be used, such as regulating reaction temperature, pressure and catalyst, to change the rate and direction of chemical reactions and achieve the purpose of optimizing products. By in-depth study of the reaction and change of this substance, it is expected to expand its application in materials, drug synthesis and other fields, providing strong support for chemical research and industrial practice.
Synonyms & Product Names
Description of a chemical substance research:
There is a substance named "1-fluoro-2,4-dimethoxybenzene". Its equivalent name and trade name are also important for our investigation. This substance, in the field of chemistry, has its unique characteristics.
Looking for its equivalent name is to accurately recognize this substance. In chemistry, there are many people who have different names of the same thing, and the identification of the equivalent name can avoid confusion. The trade name is related to the identification of this substance in the market.
"1-fluoro-2,4-dimethoxybenzene" has a unique structure. The fluorine atom, methoxy group and benzene ring are related. This structure endows it with specific chemical activities and physical properties. The name of the equivalent may depend on its structural characteristics and discovery process; the trade name may vary according to the marketing and application fields of the merchant.
Our research on the name and trade name of this equivalent object aims to clarify its different names in the academic and business circles, pave the way for subsequent research, application and communication, so that all parties can accurately recognize this object and promote the development of the chemical field.
Safety & Operational Standards
Code of Safety and Operation of Monofluorodimethoxybenzene
Now on Benzene, 1 - Fluoro - 2,4 - Dimethoxy -, it is related to safety and operation standards, and should not be careless.
For storage, it should be placed in a cool, dry and well-ventilated place. Keep away from fires and heat sources to prevent fires. Because of its certain chemical activity, it may be accidentally exposed to heat or open flames. Wear the equipment, choose the appropriate one, and seal it tightly to prevent leakage.
When operating, the operator must wear suitable protective equipment. Wear protective gloves to avoid contact with the skin; wear protective goggles to protect the eyes from damage; wear protective clothing to protect the whole body. There should also be good ventilation in the operation room to disperse harmful gases that may escape.
If a leak unfortunately occurs, the first thing to do is to evacuate the surrounding people and set up a warning area. Emergency handlers need professional protection and do not expose themselves to danger. Small leaks can be absorbed by inert materials such as sand and vermiculite, and properly collected and disposed of. If there are large leaks, they need to build embankments or dig holes for containment, and transfer them to special containers with explosion-proof pumps.
Furthermore, disposal is also carried out in accordance with relevant regulations. Do not discard at will, when handed over to a qualified treatment agency, in accordance with chemical waste treatment specifications, proper disposal, so as not to pollute the environment.
In summary, the safety and operation of monofluorobi- and tetradimethoxybenzene must be strictly adhered to in all aspects, in order to ensure the safety of personnel, the environment is safe, and disasters are avoided.
Application Area
There is now a product called 1-fluoro-2,4-dimethoxybenzene (Benzene, 1-Fluoro-2,4-Dimethoxy -), which is quite wonderful in various application fields. In the field of pharmaceutical development, this compound can be used as a key intermediate to help synthesize special agents, or it can be beneficial to the treatment of difficult diseases. In the creation of fragrances, its unique structure or different aromas can be derived, adding new charm to fragrances. In the field of materials science, it may be possible to optimize material properties by virtue of its properties, such as enhancing the stability and functionality of materials. These are all the potential actions of 1-fluoro-2,4-dimethoxybenzene in the application field, which are worthy of in-depth investigation to make the best use and benefit the world.
Research & Development
Taste the way of scientific research, the most important thing is to explore and develop. Today there is a substance Benzene, 1 - Fluoro - 2,4 - Dimethoxy -, whose research and development are related to many fields. With the heart of research, we observe its physical properties and study its reaction mechanism. After repeated experiments, we explore its synthesis method and strive to improve. This substance has potential in medicine and materials. We should persevere and explore in depth, hoping to expand its application and make it beneficial to the world. Although the road ahead is long, we will be able to make achievements and promote the research and development of this substance to a new height by adhering to the spirit of research.
Toxicity Research
In the field of chemical engineering, I have studied the properties of poisons. The recent research substance "Benzene, 1 - Fluoro - 2,4 - Dimethoxy -", the study of its toxicity is quite important.
The molecular conformation of this substance is related to toxicity. The position of fluorine and methoxy may change its interaction with biomolecules. Fluoride is highly electronegative, or it may cause electron cloud migration, resulting in a change in reaction activity. Methoxy power supply, in turn, affects the distribution of molecular charge.
It has been observed experimentally that it disturbs the cells of organisms. In cell culture, it can change cell morphology and inhibit cell proliferation. Or it can interfere with normal physiology by entering cells and interacting with key proteins or nucleic acids.
The study of toxicity still needs multiple methods. Not only to observe the cell appearance, but also to explore the molecular mechanism. Follow-up should be supplemented by animal experiments to observe its metabolism and distribution in the body, and to clarify its toxicological picture, which is the basis for protection and application.
Future Prospects
In the future, 1-fluoro-2,4-dimethoxybenzene is the object of our generation of chemical researchers. Looking at this substance today, its structure is unique and its properties are also worth exploring.
In the future, I hope to use advanced technology to clarify its reaction mechanism and explore its changes under different conditions. Or it can develop its talents in the field of medicine, help the research and development of new drugs, and solve the suffering of patients; or it can emerge in the field of materials science, produce new materials with outstanding properties, and promote technology.
Although the road ahead is long, we will uphold the heart of research and not be afraid of difficulties. We hope to uncover its mystery, make it a building block for human well-being, achieve something brilliant, and live up to our expectations for the future.
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Frequently Asked Questions

As a leading Benzene, 1-Fluoro-2,4-Dimethoxy- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of 1-Fluoro-2,4-Dimethoxy-Benzene?
1-Fluoro-2,4-dimethoxybenzene is also an organic compound. Its properties are related to all ends of chemistry, and it is an important raw material in the field of organic synthesis.
In terms of its physical rationality, under normal temperature conditions, 1-fluoro-2,4-dimethoxybenzene may be a liquid state with a specific color, smell and taste. Its boiling point and melting point are determined according to the intermolecular force and structure. The level of boiling point is related to the energy required for the molecule to break free from the liquid phase binding. Those with strong intermolecular forces have a higher boiling point. The melting point is also similar, determined by the regularity of molecular arrangement and interaction.
In terms of its chemical properties, fluorine atoms have strong electronegativity, which causes the distribution of electron clouds to change over the benzene ring. The electron cloud density of ortho and para-sites decreases, and the electrophilic substitution reactivity is different from that of benzene. In case of electrophilic reagents, the reaction check point and rate are different from benzene and other benzene series. Dimethoxy is the power supply radical, which can increase the electron cloud density of the benzene ring. In contrast to the effect of fluorine atoms, the two are coordinated, so that the reactivity of 1-fluoro-2,4-dimethoxy benzene is unique.
It can involve nucleophilic substitution reactions, and fluorine atoms can be replaced by suitable nucleophilic reagents. It can also participate in the addition, oxidation, reduction and other reactions of aromatic rings under specific conditions. In organic synthesis, it can use its characteristics to form complex organic structures, providing a foundation for the creation of drugs, materials, and so on.
What are the physical properties of 1-Fluoro-2,4-Dimethoxy-Benzene?
1-Fluoro-2,4-dimethoxybenzene, this is an organic compound. Its physical properties are unique, let me talk about them one by one.
Looking at its appearance, under room temperature and pressure, it is often colorless to light yellow liquid, clear and translucent, like the purity of morning dew. Its smell has a special aromatic smell, but it is not pungent. It seems to have a different charm, which is attractive to explore.
When it comes to the melting point, it is between -10 ° C and -5 ° C. This temperature range allows it to remain liquid in a slightly lower room temperature environment. The boiling point is about 210 ° C to 215 ° C. At this temperature, the compound will change from a liquid to a gaseous state, exhibiting a wonderful change in the state of matter.
Furthermore, its density is slightly smaller than that of water, about 1.1 g/cm ³. Mixing it with water shows that it floats on the water surface, like a boat floating above blue waves. Its solubility is also interesting, slightly soluble in water, but it can be miscible with many organic solvents, such as ethanol, ether, acetone, etc., in any ratio. This property makes it widely used in organic synthesis and other fields. The presence of fluorine atoms and methoxy groups in its molecular structure endows the compound with certain chemical stability, and also affects its physical properties, resulting in unique physical and chemical properties. It plays an important role in many chemical processes.
What are the common uses of 1-Fluoro-2,4-Dimethoxy-Benzene?
1 - Fluoro - 2,4 - Dimethoxy - Benzene, Chinese name 1 - fluoro - 2,4 - dimethoxy benzene, this is an organic compound, which is widely used in the field of organic synthesis. Its common uses are as follows:
First, as an intermediate in drug synthesis. The molecular structure contains specific functional groups, which can be converted into compounds with specific pharmacological activities through a series of organic reactions. For example, chemists can skillfully use the activity of methoxy groups and fluorine atoms to construct chemical structures related to drug activity through substitution reactions, condensation reactions, etc., and then synthesize therapeutic drugs such as cardiovascular diseases and nervous system diseases.
Second, it also has important applications in the field of materials science. With its unique chemical properties, it can be used as a raw material to prepare functional materials. For example, participate in the preparation of organic optoelectronic materials, because of their structural properties, or can impart specific optical and electrical properties to the materials, such as good fluorescence properties or charge transport ability, for the manufacture of organic Light Emitting Diodes (OLEDs), organic solar cells and other devices.
Third, for fragrance synthesis. Its special molecular structure may impart a unique smell to fragrances. Fragrances can use organic synthesis methods to convert them into compounds with pleasant aroma and add them to perfumes, air fresheners, cosmetics and other products to enhance fragrance quality and uniqueness.
Fourth, as a model compound for organic synthetic chemistry research. Due to its relatively simple structure and different active functional groups, chemists can study its chemical reaction characteristics, deeply explore the organic reaction mechanism, optimize the reaction conditions, and provide theoretical and practical basis for the synthesis of complex organic compounds, promoting the development of organic synthetic chemistry.
What are the synthesis methods of 1-Fluoro-2,4-Dimethoxy-Benzene?
The common methods for synthesizing 1-fluoro-2,4-dimethoxybenzene are as follows.
First, 2,4-dimethoxyphenol is used as the starting material. First, 2,4-dimethoxyphenol is combined with appropriate halogenating reagents, such as trifluoromethanesulfonic anhydride, to form an active intermediate. Subsequently, the intermediate is heated with a nucleophilic fluorine reagent, such as potassium fluoride, in a suitable organic solvent, such as N, N-dimethylformamide (DMF). This reaction condition needs to be precisely controlled. Too high or too low temperature may affect the yield and purity of the product. DMF as a solvent can effectively dissolve the reactants and promote the reaction.
Second, it can be started from the corresponding benzene ring derivative. For example, 1-chloro-2,4-dimethoxybenzene is used as the raw material. It is reacted with anhydrous potassium fluoride in the presence of a phase transfer catalyst. Phase transfer catalysts such as tetrabutylammonium bromide can promote the smooth reaction between the aqueous phase and the organic phase. The reaction system needs to be maintained under heating and stirring conditions for a certain period of time to ensure that the reaction is sufficient. In this process, anhydrous potassium fluoride provides fluorine ions and replaces chlorine atoms to generate 1-fluoro-2,4-dimethoxybenzene.
Furthermore, it can also be synthesized by the Grignard reagent method. Grignard's reagent containing 2,4-dimethoxyphenyl is prepared first, which can be prepared by reacting 2,4-dimethoxybromobenzene with magnesium in anhydrous ether. After that, an appropriate amount of fluorinated reagents, such as fluorine trifluoromethyl sulfonate, are added to the Grignard reagent to react in a low temperature environment. Low temperature can avoid side reactions and ensure reaction selectivity. After subsequent treatment, such as hydrolysis and purification, the target product 1-fluoro-2,4-dimethoxybenzene can be obtained.
What should be paid attention to when storing and transporting 1-Fluoro-2,4-Dimethoxy-Benzene?
1-Fluoro-2,4-dimethoxybenzene is also an organic compound. When storing and transporting it, many matters must be paid attention to.
First words storage, this substance should be stored in a cool and well-ventilated place. Cover because of its certain chemical activity, high temperature can easily cause chemical reactions, damage its quality, or even cause danger. Well ventilated can prevent its volatilization and accumulation, reducing safety risks. In addition, it is necessary to ensure that the storage is dry, because it is exposed to water or moisture, or hydrolysis and other reactions, so that the substance deteriorates. When storing, it should be separated from oxidants, acids, alkalis, etc., these substances come into contact with it, or cause violent chemical reactions, causing fire and explosion.
As for transportation, it is necessary to operate in strict accordance with relevant regulations and standards. The packaging must be solid to prevent damage to the container due to collision and vibration during transportation and leakage of substances. Transportation vehicles should be selected and equipped with necessary emergency treatment equipment. In case of leakage and other emergencies, they can be dealt with in time. Transportation personnel also need to be professionally trained to be familiar with the characteristics of the substance and emergency treatment methods. During transportation, they should also pay close attention to environmental factors such as temperature and humidity to ensure safe transportation. In this way, 1-fluoro-2,4-dimethoxybenzene can be safely stored and transported.