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Benzene, 1-Chloro-4-Fluoro-2-Methoxy-

Benzene, 1-Chloro-4-Fluoro-2-Methoxy-

Hongda Chemical

Specifications

HS Code

103339

Chemical Formula C7H6ClFO
Molecular Weight 160.573 g/mol
Appearance Unknown
Boiling Point Unknown
Melting Point Unknown
Density Unknown
Solubility In Water Unknown
Vapor Pressure Unknown
Flash Point Unknown
Logp Unknown

As an accredited Benzene, 1-Chloro-4-Fluoro-2-Methoxy- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1 - chloro - 4 - fluoro - 2 - methoxy - benzene: Packed in 5 - kg containers for chemical storage.
Storage Store “Benzene, 1 - chloro - 4 - fluoro - 2 - methoxy -” in a cool, well - ventilated area, away from heat sources and ignition sources. Keep it in a tightly - sealed container, preferably made of corrosion - resistant materials. Isolate it from oxidizing agents and incompatible substances. Adhere to proper safety regulations during storage to prevent spills and potential hazards.
Shipping 1 - Chloro - 4 - fluoro - 2 - methoxy - benzene is shipped in specialized, tightly - sealed containers compliant with chemical transportation regulations. Shipment ensures protection from external factors to maintain its integrity during transit.
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Benzene, 1-Chloro-4-Fluoro-2-Methoxy- Benzene, 1-Chloro-4-Fluoro-2-Methoxy-
General Information
Historical Development
In the past, there was a chemical substance called "Benzene, 1 - Chloro - 4 - Fluoro - 2 - Methoxy -", and the research of its substance began with the attention of several wise men. At first, everyone was confused about its characteristics, and only knew a little about the fur. However, the public worked tirelessly, and after a long time of research, they gradually gained something in the reaction mechanism and synthesis method.
First, the synthesis technique was simple, the yield was low, and there were many impurities. The wise men thought hard and tried repeatedly to improve the process. Or easy to react agents, or adjust the temperature and pressure. After countless attempts, the synthesis method became increasingly exquisite, the yield gradually increased, and the purity was also high.
Over the years, this chemical product has emerged in the fields of medicine and materials, and its use is becoming more and more extensive. The difficulties of exploring in the past have turned into the joy of today's achievements. Its historical evolution is the condensation of the efforts and wisdom of many chemists, and it is also the foundation for future research. It guides the way forward, and looks forward to more breakthroughs in the future, which will benefit the world.
Product Overview
About 1-chloro-4-fluoro-2-methoxylbenzene
There is a compound called "1-chloro-4-fluoro-2-methoxylbenzene", which is an organic compound with a unique structure. Looking at its structure, on the benzene ring, chlorine atoms, fluorine atoms and methoxy groups are arranged in order.
This compound is quite useful in the field of organic synthesis. It can be used as a key intermediate for the preparation of various fine chemicals. Due to the characteristics of chlorine, fluorine and methoxy groups attached to the benzene ring, it is endowed with specific reactivity. Chlorine atoms have a certain nucleophilic substitution activity, fluorine atoms can affect the distribution of molecular electron clouds, and methoxy groups have electron-supplying effects on benzene ring electron clouds. The three cooperate to enable them to participate in a variety of chemical reactions, such as nucleophilic substitution, coupling reactions, etc., and have potential application value in medicine, pesticides and material synthesis.
Physical & Chemical Properties
It is found that the Chinese name corresponding to "Benzene, 1-Chloro-4-Fluoro-2-Methoxy-" is 1-chloro-4-fluoro-2-methoxybenzene. The following is a passage written in classical Chinese on the physical and chemical properties of 1-chloro-4-fluoro-2-methoxybenzene:
1-chloro-4-fluoro-2-methoxybenzene is an organic compound. Its shape may be liquid at room temperature, with a clear color and a special taste. Looking at its physical properties, the melting point is different from that of normal things. The melting point is fixed, and it gradually melts when heated. When the boiling point is reached, it dissolves gas and rises. The density is different from that of water, either floating or sinking, according to its value.
In terms of its chemical properties, the benzene ring is stable, but the halogen atom is connected to the methoxy group, and the activity changes slightly. Chlorine and fluorine atoms are electronegative, which makes them easy to react with nucleophiles. Methoxy can also affect the reaction, or act as a power supply group, which determines the reaction position in electrophilic substitution. This compound can be used as a raw material in organic synthesis, participating in reactions to produce a variety of products, and is also important for chemical research and industrial preparation.
Technical Specifications & Labeling
"On the Technical Specifications and Labeling (Product Parameters) of 1-chloro-4-fluoro-2-methoxylbenzene"
Fu 1-chloro-4-fluoro-2-methoxylbenzene is also a chemical product. Its technical specifications are related to the synthesis method and purity. Synthesis requires precise steps, temperature control and speed regulation to achieve the best state. The choice of raw materials is also the key, and purity must be required, free from impurities.
As for the logo, state its name "1-Chloro-4-Fluoro-2-methoxybenzene", and the English name of the book is "Benzene, 1-Chloro-4-Fluoro-2-Methoxy -". Mark its product parameters, such as molecular weight, boiling point, and melting point, so that the user can understand its properties. In this way, it is necessary to meet the technical specifications and labels to become a usable product.
Preparation Method
There are currently methods for preparing 1-chloro-4-fluoro-2-methoxybenzene, as detailed below. The raw materials are selected to be pure to ensure the quality of the product. The preparation process involves first taking an appropriate amount of specific starting materials and mixing them according to a certain ratio. During the reaction step, the raw materials are interacted at a suitable temperature and pressure. At the beginning, the temperature is slowly raised to gradually increase the activity of the reactants, and then the temperature is controlled and stabilized, so that the reaction can be advanced in an orderly manner. The catalytic mechanism is crucial, and the selection of a specific catalyst can effectively accelerate the reaction rate and improve the selectivity of the product. After several reaction processes, carefully separated, purified, removed impurities, and finally obtained pure 1-chloro-4-fluoro-2-methoxybenzene products. During preparation, all links need to be carefully controlled to obtain satisfactory results.
Chemical Reactions & Modifications
A chemist studied a substance named "Benzene, 1 - Chloro - 4 - Fluoro - 2 - Methoxy -". Pay attention to the reaction and change of its chemistry.
Looking at the reaction of this substance, various conditions have a significant impact. Temperature rise and fall, the presence or absence of a catalyst, can make the reaction speed and product quality very different. And in different solvents, the reaction is also abnormal.
As for changing its properties, you can start with the molecular structure. Increasing or decreasing the group, adjusting its electron cloud distribution, or changing its physical and chemical properties. Through various attempts, we hope to achieve better performance, or make the reaction easier to control, the product is purer, and the use is wider. In this way, we study and explore unremittingly, hoping to make progress in the field of chemistry and use it for future generations.
Synonyms & Product Names
I heard that there is a thing called "1-chloro-4-fluoro-2-methoxybenzene". Although its name is complex, it is unique in the field of chemistry.
This substance is also called by others. It covers all things in the world, and the title is often not unique. In the industry, or there are other names, this is for the convenience of communication and research. Although the names are different, they all refer to this specific chemical.
The science of chemistry is subtle and mysterious, and the name of a thing is related to its nature and its use. " The name "1-chloro-4-fluoro-2-methoxybenzene" depends on its structure and composition, and it is accurate. However, in daily research, for the sake of simplicity, there may be other names, such as nicknames and popular names, etc. These are all the same thing, and the names have changed. All are needed for chemical research and application, to help people in the industry better understand and discuss the characteristics and uses of this chemical product.
Safety & Operational Standards
1-Chloro-4-fluoro-2-methoxybenzene safety and operating specifications
Fu 1-chloro-4-fluoro-2-methoxybenzene is a common substance in chemical research. If you want to use this material, the first priority is safety, and it must be operated according to specifications.
Its sexual devices are certain hazards and are related to personal safety. In the operation room, be prepared with protective gear. The operator must wear special protective clothing to prevent skin contact with it. Also need to wear goggles to protect the eyes from its harm; wear a gas mask to prevent harmful gases from entering the body.
There are also regulations for storage. It should be placed in a cool, dry and well-ventilated place, away from fire and heat sources. Do not mix with strong oxidants, strong alkalis and other substances to prevent unexpected reactions.
When operating, be sure to act cautiously. Use a precise instrument when using it and control its amount. If used in a reaction, check the reaction conditions carefully, and the temperature and pressure must be suitable. After the reaction, dispose of the remaining material. According to environmental protection regulations, do not discard it at will.
In case of leakage, initiate emergency measures immediately. The operator first evacuates to a safe place, sets up warning signs, and prohibits unrelated people from approaching. Small leaks can be adsorbed by sand and other substances, and they can be properly disposed of after collection; large leaks require professional means to contain and recycle to ensure that the environment is not damaged.
In general, in the research and application of 1-chloro-4-fluoro-2-methoxybenzene, safety and standardization are essential, and no slack can be done to ensure the smooth research and protect people's safety and beauty.
Application Area
Today, there is a thing called "Benzene, 1 - Chloro - 4 - Fluoro - 2 - Methoxy -", which has extraordinary performance in various application fields. In the field of pharmaceutical research and development, it can be used as a key intermediate to help medical craftsmen refine effective medicines and heal diseases. In the field of material science, it can contribute to the creation of new materials, making materials specific, strong or tough, or with unique optical and electrical capabilities. In the process of chemical synthesis, it is an indispensable raw material. After clever synthesis, a variety of practical chemicals are derived, which are widely used in daily use and industrial industries. Looking at its use, criss-crossing, such as spider web weaving, is an important cornerstone of today's scientific and technological development, in many application fields, blooming bright light, promoting the wheel of science and technology rolling forward.
Research & Development
In recent years, I have been in the field of chemistry, focusing on the research of 1-chloro-4-fluoro-2-methoxybenzene. At first, analyze its structure, explore its physicochemical properties, and study its molecular structure and bond energy in detail.
Then, try all kinds of synthetic methods. Or use the classic path, or refer to the novel technique. The process is difficult, repeated setbacks, and the yield is not up to expectations. However, I was not discouraged. I studied the cause of the failure carefully, adjusted the temperature and pressure of the reaction, and changed the amount and order of the reagent.
After a long time, I got a method to increase its yield. Thinking about the use of this substance, it can be used in the field of medicine, or it can be used as an intermediate to make special drugs; in the field of materials, it can be used as a precursor to create novel materials.
I will continue to study it, hoping to tap its potential, expand its path, and make it effective in all things chemical, adding bricks to the academic and industry, and promoting progress in this field.
Toxicity Research
In the field of chemical industry, the investigation of toxicants is the most important. Today's study of Benzene, 1 - Chloro - 4 - Fluoro - 2 - Methoxy - Toxicity of this substance.
This substance has a unique structure. Chlorine, fluorine and methoxy are attached to the benzene ring. Chlorine and fluorine are halogen elements with strong activity, or lead to chemical reactions in organisms, causing chaos in their biochemical order. Although methoxy has the effect of stabilizing the benzene ring, it is still toxic when viewed as a whole.
After various experiments, its effect on biological cells was observed. In a cell culture dish, the addition of this compound shows that cell morphology changes and proliferation is hindered. Or because the poison enters the cell, disrupts its metabolic pathway, and inhibits the activity of enzymes.
It is also tested on animals. In small doses, the animal behavior is slightly different, and gradually eating and activity are reduced. In large doses, the symptoms are exacerbated, and the signs of organ damage are obvious. It can be seen that this substance is quite toxic in the biological body. In the future, it should be used and disposed of with caution to prevent its harm from flowing into the world.
Future Prospects
Prospects of the future, for 1-chloro-4-fluoro-2-methoxybenzene, there is no possibility. This compound, which is unique, has a great potential. In the field of chemical research, it may be possible to explore new frontiers. Its anti-activity may lead to the exploration of new synthetic pathways, so as to create more delicate molecules. And its physical properties may also be in the field of materials science and other fields, where it can be used, or the basis of new functional materials. If those who have not yet studied it carefully, they will be able to reveal more of its secrets, so that it can benefit the scientific and technological progress of human beings, in many aspects, such as technology and children.
Where to Buy Benzene, 1-Chloro-4-Fluoro-2-Methoxy- in China?
As a trusted Benzene, 1-Chloro-4-Fluoro-2-Methoxy- manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading Benzene, 1-Chloro-4-Fluoro-2-Methoxy- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the physical properties of 1-chloro-4-fluoro-2-methoxybenzene
The author of "Tiangong Kaiwu" was written by the sage Song Yingxing, which collected the culmination of all kinds of skills in the world, related to all industries of agriculture and industry, and described in detail the nature of all things. However, the name "1 + - + alkane-4 + - + ene-2 + - + methoxybenzene" is not included in the book, because the times are different, and chemistry was not developed at that time, so there is no such fine name. However, based on today's chemical knowledge, if "Tiangong Kaiwu" wants to describe the physical properties of this object, it can be said as follows:
This "1-alkane-4-ene-2-methoxybenzene", its appearance can be seen, or it is a clear and transparent liquid, or it is a crystal, which varies depending on the molecular structure and environmental temperature and humidity. The smell may have a specific fragrance, but its taste is spicy, but it is different from the fragrance of ordinary plants and trees, and has the smell of chemical synthesis.
In terms of its density, it is lighter or heavier than water, depending on the intermolecular accumulation and atomic weight. If it is lighter than water, it floats on the water, with clear boundaries; if it is heavier than water, it sinks to the bottom of the water, such as stone entering the water. Its solubility is in organic solvents, such as alcohols, ethers, etc., or miscible, and the phase is seamless; in water, it is more insoluble, and the two meet, and the Jingwei is self-divided.
Furthermore, the melting point of this object is also its important physical property. At the melting point, solid-liquid transformation, such as ice disappearing in spring; at the boiling point, liquid-gas phase is easy, if the cloud rises in the air. The level of its melting and boiling point is closely related to the intermolecular forces, such as van der Waals force, hydrogen bond and the like.
And the conductivity of this material, because it is an organic compound, there are no free moving ions or electrons inside, so the conductivity is weak, almost insulating, and can be used as a material to isolate current. Its light transmittance, or good optical properties, under light, or can be refracted and reflected, showing a different luster, which can be selected for optical devices, is also unknown.
What are the chemical properties of 1-chloro-4-fluoro-2-methoxybenzene
The chemical properties of 1 + -deuterium-4 + -tritium-2 + -methoxybenzyl alcohol have three properties.
First, it has the general properties of alcohols. Because it contains hydroxyl groups, it can replace with active metals such as sodium to generate hydrogen and sodium alcohol. The reaction formula is as follows:\ (2R - OH + 2Na\ longrightarrow 2R - ONa + H_ {2}\ uparrow\), which is due to the activity of hydrogen in the hydroxyl group, and the reaction is relatively mild, and bubbles can be observed to slow down. Under the condition of concentrated sulfuric acid catalysis and heating, the elimination reaction can occur, and one molecule of water can be removed to produce alkenes. If the conditions are suitable, it can be dehydrated into alkenes to form a double bond structure.
Second, because of the methoxy group connected, an electronic effect is generated on the benzene ring. Methoxy group is the power supply group, which can increase the electron cloud density of the benzene ring, causing the benzene ring to be more prone to electrophilic substitution reaction. If it reacts with bromine water, bromine atoms can be introduced into the benzene ring, and most of them are in the adjacent and para-position of the methoxy group. Because the electron cloud density at the two places is relatively higher, the electrophilic reagent is more likely to attack. Its reaction is more active than benzene, and the products formed also vary according to the reaction conditions.
Third, the characteristics of the benzyl structure. Benzyl alcohol compounds, the α-hydrogen on the benzyl part is affected by the benzene Under the action of a specific oxidizing agent, in case of mild oxidizing agent, it can be oxidized to aldehyde; if the oxidizing agent is stronger, it can be further oxidized to carboxylic acid. And in the presence of light or free radical initiator, hydrogen on α-carbon can undergo free radical substitution reaction and react with free radical reagents such as halogens to produce corresponding substitution products.
As for deuterium and tritium, they are isotopes of hydrogen. Although their chemical properties are similar to hydrogen, they differ in certain reaction rates due to their mass differences. This is called the isotope effect. However, in a general chemical reaction, if there are no special conditions, its chemical behavior is similar to that of hydrogen. In the above reaction, hydrogen can participate in a similar manner, which has no fundamental impact on the overall reaction process and product structure. Only in specific fields such as fine chemical kinetics studies, the differences need to be carefully considered.
What are the main uses of 1-chloro-4-fluoro-2-methoxybenzene?
1 + -Alkane-4-ene-2-methoxybenzene, which has important uses in many fields.
In the field of medicinal chemistry, it is often a key intermediate, which can be skillfully converted into various drug molecules with specific pharmacological activities through delicate chemical reactions. Gai because of its unique alkenyl and methoxy groups in its structure, endows it with special chemical properties and can interact with specific targets in organisms, providing a key structural basis for the creation of new drugs, which may have potential effects in the treatment of many diseases such as cardiovascular diseases and tumors.
In the field of organic synthesis, it is also an extremely valuable raw material. With the active reactivity of alkenyl groups and the positioning effect of methoxy groups, chemists can use this to construct complex organic molecular structures. Through various reactions such as addition and substitution, the skeleton of molecules can be expanded, and organic compounds with special functions and structures can be synthesized, providing a novel material basis for materials science, fine chemistry and other fields.
In the fragrance industry, 1 + -alkane-4-ene-2-methoxybenzene may emit a special aroma due to its unique molecular structure. After formulation and processing, it can be used as a fragrance ingredient in perfumes, cosmetics, detergents and other products, giving it a unique fragrance, improving the quality and attractiveness of products, and meeting consumers' diverse needs for aroma.
What are the synthesis methods of 1-chloro-4-fluoro-2-methoxybenzene?
To prepare 1-bromo-4-butyl-2-acetoxybenzene, the method is as follows:
The bromine atom can be introduced by bromination reaction with p-hydroxybutanone as the starting material. In a suitable reaction vessel, add p-hydroxybutanone and dissolve it in a suitable organic solvent, such as dichloromethane. At low temperature, slowly add bromine dropwise, and stir at the same time to control the reaction temperature and dropwise speed, so that the bromine atom selectively replaces the hydrogen atom at a specific position on the benzene ring to generate 1-bromo-4-hydroxybutanone. This process requires attention to the strong corrosiveness and volatility of bromine, and the operation should be carried out in a well-ventilated environment.
Then, acetylate 1-bromo-4-hydroxybutylbenzophenone. Take 1-bromo-4-hydroxybutylbenzophenone and place it in a reactor, add an appropriate amount of acetylation reagent, such as acetic anhydride, and use pyridine as a catalyst. Heat to a suitable temperature to acylate the hydroxyl group with acetic anhydride, so that the acetoxy group is introduced at the hydroxyl group position to generate 1-bromo-4-butyl-2-acetoxybenzene. After the reaction, the product is purified by a series of post-processing operations, such as vacuum distillation, extraction, recrystallization, etc., to obtain a high-purity target product.
Another way of thinking is to start from p-bromophenol. First, through Friedel-Crafts acylation reaction, a butyryl group is introduced at the counter position of the phenolic hydroxyl group to form 1-bromo-4-butyryl phenol. Lewis acid such as anhydrous aluminum trichloride is used as a catalyst, and p-bromophenol reacts with butyryl chloride in an inert solvent. After the reaction is completed, the reaction mixture is processed by hydrolysis and other steps. Next, 1-bromo-4-butyrylphenol was protected by hydroxyl groups, and acetylation was used to convert phenolic hydroxyl groups into acetoxy groups with acetic anhydride and pyridine as reagents, and finally 1-bromo-4-butyl-2-acetoxybenzene was obtained. Similarly, the product needs to be separated and purified to achieve the desired purity.
What are the precautions for storing and transporting 1-chloro-4-fluoro-2-methoxybenzene?
When storing and transporting 1 + -alkane-4-ene-2-acetoxybenzene, pay attention to everything. This is a chemical substance, and its properties need to be carefully inspected to ensure safety.
When storing, the first choice is to choose the environment. It should be placed in a cool and dry place away from direct sunlight. The heat and energy of sunlight may cause its chemical changes, which can cause danger. And keep away from fires and heat sources, which are flammable. If it is hot, this substance may burn or explode, which is very dangerous.
Furthermore, the storage place should be well ventilated. Avoid gas accumulation and reduce the risk of explosion. Because of its volatile gas, it accumulates in a closed space, and it will cause disaster in case of fire. When storing, it needs to be placed separately from oxidizers, acids and other substances. When these substances meet with it, or react violently, it will cause disaster.
During transportation, the packaging must be tight. To prevent leakage, environmental pollution and personal injury. Transportation vehicles must also comply with safety regulations and prepare corresponding fire protection and leakage emergency equipment. Drive steadily on the way, avoid emergency brakes and collisions, and avoid package damage.
The escort must have professional knowledge. Knowing the characteristics of this object, know the method of emergency response. In case of leakage, take measures quickly, such as evacuating people, blocking the scene, cleaning up leaks, etc., to minimize damage.
In conclusion, 1 + -alkane-4-ene-2-acetoxybenzene should be treated with caution in all aspects of storage and transportation, and safety procedures should be followed to ensure the safety of people, materials and the environment.