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Benzene, 1-Bromo-4-Methoxy-2-(Trifluoromethyl)-

Benzene, 1-Bromo-4-Methoxy-2-(Trifluoromethyl)-

Hongda Chemical

Specifications

HS Code

798866

Chemical Formula C8H6BrF3O
Molecular Weight 255.03
Appearance Typically a colorless to pale - yellow liquid or solid (depending on conditions)
Boiling Point Data may vary, but generally in the range where aromatic - halide - substituted compounds boil, likely around 200 - 250°C
Melting Point Specific value would need experimental determination, but for similar aromatic compounds can be in the range of 30 - 80°C
Density Approximate density around 1.6 - 1.8 g/cm³ (estimation based on similar halogen - and fluorine - containing aromatic compounds)
Solubility In Water Insoluble in water due to non - polar aromatic and fluorinated groups
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform, toluene
Vapor Pressure Low vapor pressure at room temperature, as it is a relatively high - molecular - weight and non - volatile compound
Flash Point Requires experimental determination, but likely above 100°C considering its molecular structure and volatility

As an accredited Benzene, 1-Bromo-4-Methoxy-2-(Trifluoromethyl)- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 1 - bromo - 4 - methoxy - 2 - (trifluoromethyl)benzene in a sealed chemical - grade bottle.
Storage Store "Benzene, 1 - bromo - 4 - methoxy - 2 - (trifluoromethyl)-" in a cool, dry, well - ventilated area away from heat, sparks, and open flames. Keep it in a tightly - sealed container, preferably made of corrosion - resistant materials. Isolate from oxidizing agents and incompatible substances to prevent chemical reactions. Label the storage clearly for easy identification and safety.
Shipping Ship "1 - bromo - 4 - methoxy - 2 - (trifluoromethyl)benzene" in well - sealed, corrosion - resistant containers. Ensure compliance with hazardous chemical shipping regulations, with proper labeling and documentation for safe transportation.
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Benzene, 1-Bromo-4-Methoxy-2-(Trifluoromethyl)- Benzene, 1-Bromo-4-Methoxy-2-(Trifluoromethyl)-
General Information
Historical Development
In the field of chemistry, there is a thing called "Benzene, 1 - Bromo - 4 - Methoxy - 2 - (Trifluoromethyl) -". The origin of its object was initially hidden in a mystery. In the past, all the sages searched in the world of chemistry. At the beginning, the knowledge of this object was still shallow, and only a glimpse of it was a corner.
However, the masters were not discouraged, and they worked tirelessly. After repeated experiments and analysis, its characteristics gradually became clear. From ignorance to clarity, from the end of observation, the foundation of knowledge is exhausted. Everyone searched between bottles and cans, and with wisdom and perseverance, drew a picture of the evolution of this object.
With the passage of time, the cognition of "Benzene, 1 - Bromo - 4 - Methoxy - 2 - (Trifluoromethyl) -" has deepened, and its use in various fields has gradually shown, just like a pearl, opening a new journey of chemical exploration.
Product Overview
"On the tasting of 1-bromo-4-methoxy-2 - (trifluoromethyl) benzene"
There is now a product called 1-bromo-4-methoxy-2 - (trifluoromethyl) benzene. Its shape and color, at room temperature, or in a liquid state, are clear and slightly shiny. The taste and smell of it have a specific smell, so you should not rashly smell it to prevent damage to the body.
The properties of this product are unique in the field of chemistry. In its structure, the arrangement of bromine atoms, methoxy groups and trifluoromethyl groups makes its chemical activity unique. Bromine atoms can lead to changes in nucleophilic substitution, methoxy groups can affect the distribution of electron clouds, and the strong electron-absorbing properties of trifluoromethyl groups add variables to the reaction path of this substance.
In the process of synthesis, it is often a key raw material. Cleverly designed reactions may give rise to many useful compounds, which are potentially useful in medicine, materials and other industries.
However, this substance also has risks. When handling, it must comply with chemical regulations and heavy protection to ensure safety.
Physical & Chemical Properties
There is now a substance named 1-bromo-4-methoxy-2 - (trifluoromethyl) benzene, whose physicochemical properties are quite important. The color state of this substance may be a specific shape or a special smell at room temperature. Its melting point and boiling point are the keys to characterizing its physical properties. As for chemical properties, it is active because its structure contains bromine atoms, methoxy groups and trifluoromethyl groups. Bromine atoms can participate in substitution reactions. Methoxy groups have an effect on the distribution of electron clouds in the benzene ring, and trifluoromethyl groups give it unique chemical activity. Under specific conditions, it can react with a variety of reagents to form different products. The study of the physical and chemical properties of this substance is of great significance in the fields of chemical synthesis, materials science, etc., which can help researchers expand their understanding and explore new application directions.
Technical Specifications & Labeling
Today there is a product called "Benzene, 1 - Bromo - 4 - Methoxy - 2 - (Trifluoromethyl) -". In the field of my chemical research, its technical specifications and identification (commodity parameters) are the key. Looking at this substance, its structure is unique, containing bromine, methoxy and trifluoromethyl based on the benzene ring.
In order to understand its technical specifications, it is necessary to study the synthesis method in detail. The purity of the raw material, the temperature of the reaction, and the control of time are all important. The reaction device is also exquisite, and the material, volume, etc. are all related to the result. In terms of identification, the name should be accurate, the molecular formula and structural formula should be clear, the physical properties such as color, taste, melting point, and chemical properties such as stability and reactivity should be clearly marked. In this way, the substance can be used in research and application, and it can be followed without error.
Preparation Method
1-Bromo-4-methoxy-2 - (trifluoromethyl) benzene is prepared in this way. The first raw materials are p-methoxyacetophenone, bromine, trifluoroacetic anhydride, etc. The method of preparation is to react p-methoxyacetophenone and bromine in an appropriate solvent under temperature control to obtain bromide. This step requires strict observation of the reaction process and timely regulation.
Next, the bromide is co-placed in a reactor with trifluoroacetic anhydride and an appropriate amount of catalyst. After specific conditions, the bromide group is converted and trifluoromethyl is introduced. The key to this reaction is to accurately control the temperature and control, and to ensure that the material ratio is appropriate.
In addition, the reaction device needs to be properly designed, with good condensation and mixing mechanisms to promote the reaction to be sufficient and uniform. In this way, through a series of steps, 1-bromo-4-methoxy-2 - (trifluoromethyl) benzene can be prepared. The whole preparation process, all links are interlocked, and all need to be carefully controlled to obtain satisfactory products.
Chemical Reactions & Modifications
The wonder of Guanfu chemistry is that the reaction and modification of 1-bromo-4-methoxy-2 - (trifluoromethyl) benzene is the key to chemical investigation. The reaction of this compound often involves many chemical mechanisms. The method of the past may have complicated disadvantages, and the product may be impure.
Today's chemists strive to change. After repeated research, the reaction conditions are improved, such as temperature control and catalyst selection, to optimize the reaction path. This move can also increase the reaction rate and increase the selectivity of the product.
The modification of this compound aims to expand its use. By chemical means, new groups are introduced and their physical and chemical properties are changed, making them suitable for a variety of fields, such as medicine and materials. Chemists have worked tirelessly to explore the secrets of chemistry and benefit everyone, so that this compound can be reborn in the reaction and modification, and bloom in the chemical way.
Synonyms & Product Names
There is a substance today called 1-bromo-4-methoxy-2 - (trifluoromethyl) benzene. This substance is of great research value in the field of chemistry. Its aliases also exist, or are called differently due to differences in exploration perspectives and uses.
There are many names for chemical substances, and there are many names for the same thing and different names. This 1-bromo-4-methoxy-2 - (trifluoromethyl) benzene, or in the process of synthesis, has unique capabilities. Chemists give different names because of its characteristics and structure, which is convenient for discussion and communication.
Looking at its name, one or two of its structures can be seen. Bromine, methoxy, and trifluoromethyl groups are attached to the benzene ring, each of which exhibits its own properties and interacts, resulting in its unique chemical properties. When chemists explore, they call it by different names according to its reaction and use. This is the origin of the synonym and trade name of the same thing.
Safety & Operational Standards
1-Bromo-4-methoxy-2 - (trifluoromethyl) benzene safety and operating specifications
Fu 1-bromo-4-methoxy-2 - (trifluoromethyl) benzene, the product of the chemical. Its nature is special, related to safety and operating standards, must not be ignored.
#1. Storage essentials
This thing should be stored in a cool, dry and well ventilated place. Keep away from fire and heat sources to prevent accidents. It should be stored separately with oxidants and edible chemicals, and must not be mixed to avoid disasters. At the time of storage, the corresponding variety and quantity of fire-fighting equipment and leakage emergency treatment equipment should be prepared. The packaging should be sealed and not exposed to the air to prevent deterioration.
#2. Rules of Operation
When operating, it must be carried out in a fume hood, and the operator must wear appropriate protective equipment. Wear chemical safety glasses to prevent splashing into the eyes; wear anti-toxic substances to penetrate the work clothes to prevent them from infringing the skin; wear rubber gloves to keep the hands safe. During operation, try to handle it with care to avoid damage to its containers. It is strictly forbidden to eat, drink and smoke in the workplace to prevent accidental ingestion and inhalation.
#3. Emergency disposal
If accidental leakage occurs, personnel in the contaminated area should be quickly evacuated to a safe area, and quarantined, and access should be strictly restricted. Emergency personnel must wear self-contained positive pressure breathing apparatus and anti-virus clothing. Do not let leaks come into contact with combustible substances. In the event of a small amount of leakage, it can be absorbed by sand, vermiculite or other inert materials. Large leaks need to be built embankments or dug for containment, covered with foam to reduce vapor disasters. Then, transfer to a tanker or a special collector with a pump, recycled or transported to a waste treatment site for disposal.
#4. Disposal
When discarded, relevant regulations should be followed. It cannot be discarded at will and needs to be handed over to a qualified unit for disposal. According to its chemical properties, suitable methods are used to degrade or transform it to make it harmless and ensure the safety of the environment.
In short, in the use and storage of 1-bromo-4-methoxy-2 - (trifluoromethyl) benzene, strictly abide by safety and operating standards, in order to obtain the stability of chemical research and avoid the danger of accidents.
Application Area
Today there is a product called 1-bromo-4-methoxy-2 - (trifluoromethyl) benzene. This product has wonderful uses in many fields. In the field of medicine, it can be used as a key raw material for synthesizing special drugs, helping doctors relieve people's pain. In the field of materials, it can participate in the creation of novel functional materials, or have unique optical and electrical properties, which are widely used in electronic equipment, etc., to improve their performance. In the field of fine chemicals, a variety of high-value-added products can be derived through exquisite processes, such as high-end fragrances, special additives, etc., adding luster to the chemical industry. The application field of this compound has broad prospects, like a star, illuminating many fields of technology and life, which is an indispensable treasure in chemical research and industrial production.
Research & Development
At present, 1-bromo-4-methoxy-2 - (trifluoromethyl) benzene is studied, which is quite useful in various fields of chemical industry. At first, to obtain this product, various methods were complicated and the yield was not good. We have dedicated ourselves to studying the reaction conditions in detail, such as temperature, ratio of reagents, catalyst, etc.
After repeated tests, when the temperature is moderate and the proportion of reagents is appropriate, with a specific catalyst, the effect is obtained, and the yield is significantly improved. And the product is also of high purity. This achievement may reduce its cost and increase its efficiency in industrial production.
Thinking about its future development, it may be used in fields such as pharmaceutical synthesis and material research and development. We should make unremitting efforts to tap the potential of this product, contribute to the development of the chemical industry, and promote its rapid change to benefit everyone.
Toxicity Research
The chemical industry is related to people's livelihood, but the study of poisons should not be careless. Today there is a name "Benzene, 1 - Bromo - 4 - Methoxy - 2 - (Trifluoromethyl) -". For our chemical researchers, the study of its toxicity is crucial.
This compound has a unique structure and contains bromine, methoxy group and trifluoromethyl based on the benzene ring. Its toxicity may involve multiple ends, or damage human organs, or disrupt the order of physiology. When studying, when following the ancient method, be careful to observe its nature. Observe its response to other things, measure its changes in different environments, and record its situation in detail to explain its toxicity.
Our generation of chemical researchers, shouldering a heavy responsibility, will devote all their efforts to the study of the toxicity of "Benzene, 1 - Bromo - 4 - Methoxy - 2 - (Trifluoromethyl) -" to ensure the well-being of the world and not to make the harm of poisons invisible.
Future Prospects
Looking at the research of chemistry today, I have endless expectations for 1-bromo-4-methoxy-2 - (trifluoromethyl) benzene. This material is unique in nature and exquisite in structure, and it seems to have extraordinary potential in the field of organic synthesis.
Looking to the future, it may be used to create new drugs and open up a path for the treatment of sinking diseases. Its special structure may accurately fit the target of the disease, making the drug more effective. Or it may emerge in material science and lay the foundation for new functional materials. With its stability and activity, it may be able to prepare materials with good weather resistance and excellent performance, which can be used in aerospace, electronics and other fields.
Although the road ahead is long, the road of scientific exploration is full of unknowns and surprises. Our chemical researchers, with sincerity and unremitting research, hope to explore the potential of 1-bromo-4-methoxy-2 - (trifluoromethyl) benzene in the future and contribute to human well-being.
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Frequently Asked Questions

As a leading Benzene, 1-Bromo-4-Methoxy-2-(Trifluoromethyl)- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of this product 1-bromo-4-methoxy-2 - (trifluoromethyl) benzene
This is an organic compound named 1-bromo-4-methoxy-2 - (trifluoromethyl) benzene. Its chemical properties are particularly important and are related to reactions and applications in many chemical and related fields.
In this compound, the bromine atom has high electronegativity, which increases the polarity of the molecule. In nucleophilic substitution reactions, the bromine atom is a good leaving group, which is easily attacked by nucleophiles, which in turn triggers a substitution reaction to generate new organic compounds. For example, when encountering nucleophiles such as hydroxyl anions, the bromine atom may be replaced by a hydroxyl group to produce corresponding phenolic derivatives.
Methoxy (-OCH 🥰) is the electron donor group, which can give electricity to the benzene ring through the conjugation effect, so that the electron cloud density of the benzene ring increases. In the electrophilic substitution reaction on the benzene ring, the methoxy group is an ortho-and para-localization group, which can guide the electrophilic reagent to attack the ortho-and para-localization of the benzene ring, so that the reaction is more likely to occur at this position.
Trifluoromethyl (-CF 🥰) is a strong electron-absorbing group, because of its extremely high electronegativity, it can significantly reduce the electron cloud density of the benzene ring. This effect not only affects the electrophilic substitution activity of the benzene ring, but For example, the presence of trifluoromethyl groups often enhances the fat solubility of compounds, which may be of great significance in the field of medicinal chemistry, or may affect the ability of drug molecules to penetrate biofilms.
In addition, the stability of the compound is also affected by the interaction of various groups. The opposite effect of methoxy groups and trifluoromethyl groups on the electron cloud density of the benzene ring, or the uneven distribution of electron clouds on the benzene ring, has a subtle effect on molecular stability. Under different reaction conditions, or due to the interaction between groups, it presents unique chemical behaviors, providing a variety of reaction paths and potential applications for organic synthetic chemistry.
What are the main uses of 1-bromo-4-methoxy-2- (trifluoromethyl) benzene?
1 + -Elm-4-methoxy-2- (triethoxy) benzene, this substance has a wide range of uses.
One of them is in the field of medicine, which has certain medicinal value. Elm, known as "Summer Moon Ephedra", has a lukewarm nature and a refreshing taste. It can sweat and dissolve the surface, dehumidify and reduce swelling. Combining it with the part containing methoxy and triethoxy benzene structures, or it can borrow the properties of Elm, so that the compound can play a unique role in the treatment of certain diseases. For example, in the symptoms of exogenous summer and dampness, aversion to cold and fever, heavy head and body sleepiness, chest tightness, or it can be used to dissolve the surface, dehumidify and neutralize, and improve symptoms.
Second, in the fragrance industry, because it contains a specific chemical structure, it may emit a unique aroma. Methoxy and triethoxy benzene parts may give their aroma a unique level and tone, while Elm itself also has a certain aroma. The combination of the two may become a key ingredient in the formulation of new fragrances. It is used in perfumes, air fresheners, aromatherapy and other products to add a unique fragrance.
Third, in the field of organic synthesis, as an organic compound, the structure of various functional groups, such as methoxy, triethoxy, etc., provides a rich reaction check point for organic synthesis. Chemists can use these functional groups to perform various organic reactions, such as substitution reactions, addition reactions, etc., to synthesize more complex and functionally specific organic compounds, providing important intermediates for the development of organic synthetic chemistry.
What is the preparation method of 1-bromo-4-methoxy-2 - (trifluoromethyl) benzene?
To prepare 1-bromo-4-methoxy-2- (trifluoromethyl) benzene, you can follow the following method:
First take an appropriate amount of p-methoxybenzaldehyde and place it in a clean reaction vessel. Slowly add a solution containing a brominating agent dropwise to it, and carry out a bromination reaction under suitable temperature and stirring conditions. This step aims to introduce bromine atoms into the benzene ring, with p-methoxy groups as positioning groups, so that bromine atoms mainly replace their ortho-sites, so as to obtain bromine-containing benzaldehyde intermediates.
After the bromination reaction is completed, cool down the reaction system, and carefully add a specific reducing agent to convert the aldehyde group into a hydroxyl group to obtain the corresponding alcohol intermediate. When operating, pay attention to the amount of reducing agent and reaction conditions to prevent excessive reduction.
Subsequently, halogenate the intermediate containing hydroxyl groups. Select a suitable halogenation reagent, and under appropriate solvent and reaction conditions, convert the hydroxyl group into a halogen atom. The halogen atom and the trifluoromethyl group to be introduced should be in a suitable relative position to facilitate subsequent reactions.
Then mix the intermediate after the halogenation reaction with the trifluoromethylation reagent. Under the action of the catalyst, the trifluoromethyl group is substituted for the position of the halogen atom to obtain the target product 1-bromo-4-methoxy-2 - (trifluoromethyl) benzene. During the reaction process, the reaction temperature, pressure and reaction time need to be strictly controlled to ensure the smooth progress of the reaction and the purity of the product.
Finally, the reaction products are separated and purified. Methods such as distillation, extraction, column chromatography, etc. can be used to remove residual impurities in the reaction system, unreacted raw materials and by-products, so as to obtain high-purity 1-bromo-4-methoxy-2 - (trifluoromethyl) benzene.
What are the precautions for storing and transporting 1-bromo-4-methoxy-2- (trifluoromethyl) benzene?
1 + - + ether + - + 4 + - + methoxy + - + 2 + - + (triethoxy) silicon must pay attention to the following matters during storage and transportation:
First, when storing, choose a cool, dry and well-ventilated place. This is because of its active chemical properties, and it is easy to cause deterioration in case of high temperature and humidity, resulting in damage to its performance. If placed in a humid place, moisture is prone to react with the ethoxy group on the silicon atom, resulting in hydrolysis, which in turn destroys the molecular structure and reduces its application efficiency.
Second, it should be kept away from fire and heat sources. Ether substances are flammable, and ether groups in this compound are no exception. Once it is close to a fire or heat source and reaches its ignition point, it is very easy to catch fire, or even cause an explosion, resulting in a major disaster.
Third, the storage container must be tightly sealed. If the seal is not good, oxygen, moisture and other impurities in the air are easy to invade and chemically react with the compound. For example, oxygen may oxidize some of the groups, change its chemical properties, and affect product quality.
Fourth, during transportation, ensure that the container is stable and avoid collisions and vibrations. The structure of this compound is relatively delicate, and violent collisions or vibrations may cause chemical bonds within the molecule to break, triggering decomposition reactions. And if the vibration causes the container to be damaged and the compound to leak, it will also bring many safety hazards.
Fifth, the transportation and storage places should be equipped with appropriate fire protection and leakage emergency treatment equipment. In the event of a fire, fire extinguishing equipment can be used in time to put it out; if there is a leak, effective measures can be taken immediately to collect and deal with the leak to prevent pollution of the environment and other hazards.
Sixth, the operator and the person in contact should take protective measures. This compound may be irritating and harmful to the human body, and may cause damage if it comes into contact with the skin, eyes or inhalation. Therefore, appropriate protective gloves, goggles and gas masks should be worn.
What are the market prospects for 1-bromo-4-methoxy-2 - (trifluoromethyl) benzene?
The market prospects of 1 + -hydroxyl-4-methoxy-2- (triethoxy) silicon are actually related to various factors and are complex.
Nowadays, this compound is increasingly used in various industrial fields. At the end of material preparation, due to its special chemical structure, it can be used as a key raw material to synthesize materials with outstanding properties. For example, the preparation of some high-end coatings and sealants, the addition of this material can greatly improve the weathering resistance and adhesion of products, so the demand for construction, automobile manufacturing and other industries is growing. The construction industry pursues long-lasting and durable materials, and the automobile manufacturing wants better protection and stability of components, which are all opportunities for its market expansion.
However, although the market prospect is bright, there are also challenges. Its synthesis process may be complicated, and cost control is the key. If the process can be optimized, the cost can be reduced and the efficiency can be increased, it can take the lead in the market competition. And similar alternative products in the market also pose a threat to it. Substitutes with similar performance and lower cost may cause their market share to be eroded.
Furthermore, the impact of policies and regulations cannot be ignored. If the environmental protection policy is stricter, if the production and use of this compound do not meet the relevant environmental protection standards, it will be hindered. On the contrary, if it can conform to the trend of green development and the development environment-friendly production path, it will be able to win more market favor.
In summary, the market prospect of 1 + -hydroxyl-4-methoxy-2- (triethoxy) silicon, opportunities and challenges coexist. Only by understanding market demand, improving technology, and responding to policies can we ride the waves in the market and seek development.