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Benzene, 1-Bromo-4-Fluoro-5-Methyl-2-Nitro-

Benzene, 1-Bromo-4-Fluoro-5-Methyl-2-Nitro-

Hongda Chemical

Specifications

HS Code

384321

Chemical Formula C7H5BrFNO2
Molar Mass 236.02 g/mol
Appearance Solid (predicted)
Solubility In Water Low (predicted)
Vapor Pressure Low (predicted)
Logp Around 3 (predicted)

As an accredited Benzene, 1-Bromo-4-Fluoro-5-Methyl-2-Nitro- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100 - gram vial of 1 - bromo - 4 - fluoro - 5 - methyl - 2 - nitro - benzene, well - sealed.
Storage Store "1 - bromo - 4 - fluoro - 5 - methyl - 2 - nitro - benzene" in a cool, dry, well - ventilated area, away from heat and ignition sources. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials like glass or certain plastics. Separate it from oxidizing agents, reducing agents, and reactive substances to prevent dangerous reactions.
Shipping 1 - Bromo - 4 - fluoro - 5 - methyl - 2 - nitro - benzene, a hazardous chemical, is shipped in tightly sealed, corrosion - resistant containers. It follows strict regulations, with proper labeling for safety, and is transported by approved carriers handling such substances.
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Benzene, 1-Bromo-4-Fluoro-5-Methyl-2-Nitro- Benzene, 1-Bromo-4-Fluoro-5-Methyl-2-Nitro-
General Information
Historical Development
About the historical development of 1-bromo-4-fluoro-5-methyl-2-nitrobenzene
Ancient chemical research, although it began in a small way, the way of evolution is all step by step. In the field of organic compounds, 1-bromo-4-fluoro-5-methyl-2-nitrobenzene has also been pondered over the years.
At the beginning, the understanding of organic chemistry was not clear, and it was very difficult to distinguish the quality of the analytes. As the research of scholars deepened, the mystery of organic structure was gradually solved, and the method of synthesis was gradually emerging.
In the past, organic synthesis relied only on the simplification of natural substances, and later it was gradually able to create complex structures by artificial methods. The preparation of 1-bromo-4-fluoro-5-methyl-2-nitrobenzene originated from chemists' familiarity with reactions such as halogenation, nitrogenation, and methylation.
At first, it was not easy to control the halogenation reaction, and it was difficult to introduce fluorine and bromine accurately. Nitrogenation also requires careful selection of conditions to avoid side reactions clumping. Methylation steps are also related to the purity of the product.
With the advancement of chemical technology, the reaction conditions are gradually improved, and the yield and purity increase. The complicated process of the past has been simplified. This compound has gradually shown its use in the fields of medicine and materials, and has also witnessed the brilliant evolution of the history of chemistry.
Product Overview
A chemical substance is called "Benzene, 1 - Bromo - 4 - Fluoro - 5 - Methyl - 2 - Nitro -". This substance has a unique structure. On the benzene ring, bromine atoms, fluorine atoms, methyl and nitro groups are in their respective positions. Bromine is in the 1st position, fluorine is in the 4th position, the 5th position is methyl, and the 2nd position is nitro.
Its properties are different, or it has certain reactivity. Due to the halogen atom properties of bromine and fluorine, it may participate in reactions such as nucleophilic substitution. The existence of nitro groups also affects the distribution of molecular electron clouds, making its chemical behavior unconventional. Although methyl is relatively stable, it also plays a role in the overall properties.
This substance is used in the field of chemical research, or as an important intermediate. After various reactions, a variety of compounds can be derived, providing many possibilities for organic synthesis and other aspects of research. We need to explore it in depth to understand more mysteries.
Physical & Chemical Properties
1-Bromo-4-fluoro-5-methyl-2-nitrobenzene, the physical and chemical properties of this substance are related to many things. Its physical properties, viewed at room temperature, may have a characteristic color state. Or as a solid, its color may be present, or colorless, or with a yellowish tone, depending on the presence or absence of impurities. Its melting point and boiling point are also key. The melting point is related to its physical state transition temperature, and the boiling point is related to the time of gasification. Chemically, because its structure contains functional groups such as bromine, fluorine, and nitro, its chemical activity is unique. Nitro has strong oxidizing properties, which can change the electron cloud density of the benzene ring and affect the electrophilic substitution reaction activity. Bromine and fluorine atoms, due to their electronegativity differences, also affect the reactivity of the benzene ring, or exhibit characteristics in nucleophilic substitution and other reactions. In the field of organic synthesis, their physicochemical properties determine their uses, and they are the key raw materials for the preparation of specific compounds.
Technical Specifications & Labeling
There is a product today, called "Benzene, 1 - Bromo - 4 - Fluoro - 5 - Methyl - 2 - Nitro -", to clarify its technical specifications and identification (product parameters).
When looking at this substance, the first priority is its quality. Its quality must be pure, and impurities should not be disturbed, so as to comply with specific regulations. Regarding its identification, the number of elements contained must be specified, and the positions and amounts of bromine, fluorine, methyl, and nitro should be confirmed so that people can understand.
In the technical specifications, the preparation method should be fine. The temperature and time of the reaction, and the ratio of materials are all important. The preparation environment should not be neglected, clean and orderly, in order to ensure its quality. The method of storage also has rules. Avoid water and fire, prevent exposure, and choose the hiding place according to its nature to extend its effect. In this way, the "Benzene, 1 - Bromo - 4 - Fluoro - 5 - Methyl - 2 - Nitro -" can be used in all kinds of things to the best of its ability, without violating its technical specifications and labeling requirements.
Preparation Method
The method of making Benzene, 1 - Bromo - 4 - Fluoro - 5 - Methyl - 2 - Nitro - is related to the raw materials and production process, reaction steps and catalytic mechanism.
Its raw materials need to be prepared with specific organic reagents, with accurate proportions and no difference. Production process, the first environmental control, temperature and humidity are fixed. Reaction step, initially mix the materials, slowly stir the temperature, to a specific temperature, see the color change slightly, this is the beginning of the reaction. Continue to stabilize the temperature, observe the change, and add the agent in time to promote the smooth reaction.
Catalytic mechanism, Wright's agent can reduce the resistance of the reaction and speed up the process. In this way, following this procedure and step by step carefully, Benzene, 1 - Bromo - 4 - Fluoro - 5 - Methyl - 2 - Nitro - can be prepared, and the quality is also guaranteed.
Chemical Reactions & Modifications
To taste the wonders of chemical industry, it is related to the change of substances, reaction and modification, which is really the key. Today there is a substance "Benzene, 1 - Bromo - 4 - Fluoro - 5 - Methyl - 2 - Nitro -", and its chemical reaction and property improvement are particularly important.
The chemical reaction of the husband, or the addition of reagents, or the change of its conditions, makes the molecular structure easier and the properties are changed. In this substance, the positions of bromine, fluorine, methyl, and nitro can be observed, and the reaction path can be considered. For example, bromine and fluorine can be replaced by nucleophilic substitution, which makes their properties different. Methyl may affect the distribution of electron clouds, while nitro groups are related to the activity of the reaction.
The way of modification, either to enhance stability, or to change solubility, reactivity, etc. With the ancient method, investigate its chemical principles, expect to obtain new properties in reaction and modification, so that it can be used in industry and scientific research. It adds to the progress of chemistry, explores the wonders of material changes, and uses its principles to open up new paths in the future.
Synonyms & Product Names
Today there is a product called "Benzene, 1 - Bromo - 4 - Fluoro - 5 - Methyl - 2 - Nitro -". The same product name of this product is worth exploring.
If the husband is the same or similar, it can represent the same or similar. And the trade name is the name used in the circulation of the business. These two, or due to differences in regions and practices, give rise to many problems.
To clarify their similarity, it is necessary to go through the classics, study the literature, or illuminate the classics of the product, so as to make it possible. As for the trade name, it is necessary to involve the business, the market, in order to get something.
Studying the same trade name of this item is beneficial for ease of communication and trade. It can make the product more refined and avoid the risk of confusion.
Safety & Operational Standards
1-Bromo-4-fluoro-5-methyl-2-nitrobenzene Safety and Operating Specifications
If you want to make 1-bromo-4-fluoro-5-methyl-2-nitrobenzene (Benzene, 1-Bromo-4-Fluoro-5-Methyl-2-Nitro -), you must first clarify its safety and operating specifications to ensure that everything goes smoothly and is safe from risk.
#1. Preparation environment
The preparation place should be spacious and ventilated, so that the turbid gas can escape and clear air can enter. Do not place flammable or explosive objects around to prevent accidents. For lighting equipment, use explosion-proof ones to avoid disasters caused by electric fire. All equipment used must be clean and dry to avoid impurities and impure products.
#2. Use of raw materials
When taking raw materials, be careful. Bromine is highly corrosive and highly toxic. Take it in front of protective equipment, such as thick gloves, goggles, gas masks, etc. When removing, it should be in a fume hood to prevent it from hurting people. Fluoride is also toxic, and should not be slack during operation. Methyl compounds are flammable, keep away from fire sources. Nitro compounds are explosive, handle them with care, and do not subject them to shock and pressure.
#3. Reaction operation
When reacting, temperature control is the key. Use a water bath or an oil bath to adjust it, slowly heat up, and observe its changes. Stirring must be uniform to make the reaction sufficient. Do not make the temperature change abruptly, causing the reaction to run out of control. If there is any abnormality, such as odor, color change, or abnormal sound, stop it quickly and check the cause.
#4. Product treatment
The product has been obtained, and the separation and purification must also be in compliance. When distilling, pay attention to the temperature, so that the product can be distilled out in an orderly When filtering, filter paper utensils must be adapted. The purified product should be stored in a special container, properly sealed, and marked with the name, date, etc.
#5. Personnel protection and emergency
Those who prepare it must know the rules of safety and the methods of familiar operation. Once contaminated with raw materials, rinse with water quickly, and seek medical attention for those who are serious. In case of fire, use a fire extinguisher such as dry powder and carbon dioxide as appropriate. When leaking, quickly contain and clean up to prevent its spread.
In short, to make 1-bromo-4-fluoro-5-methyl-2-nitrobenzene, safety is the first priority, and the operation is in accordance with the rules, so that it can be achieved without danger.
Application Area
Guanfujin's chemistry has the name "Benzene, 1 - Bromo - 4 - Fluoro - 5 - Methyl - 2 - Nitro -", which is widely used. In the field of medicine, it can be used as a raw material to make special agents to treat various diseases and help patients recover. In the manufacture of materials, it can be used as a key component to enhance the properties of materials, make them strong and durable, and the equipment and utensils used are all good because of it. It is also used for scientific research and exploration, the cornerstone of scholars' research on new theories and innovative methods, and to help the academic community break through difficulties and expand new knowledge. This substance in various application fields, all have their unavoidable ability, just like the stars shining at night, shining brightly, promoting all things forward, for the benefit of the world.
Research & Development
Wutao is dedicated to the research of 1-bromo-4-fluoro-5-methyl-2-nitrobenzene. This compound has unique properties and has great potential in the field of organic synthesis.
Initially explore its structure and reactivity, and try to prepare it by classical organic synthesis method. During the process, many reaction conditions need to be fine-tuned, such as temperature, catalyst type and dosage. After repeated tests, a feasible method is finally obtained, but the yield still needs to be improved.
In order to promote its development, the follow-up consideration is to optimize the synthesis path and try new catalysts or reaction media. The possibility of its application fields such as drug synthesis and material preparation is also explored. Although the road ahead is long, I firmly believe that with continued research, we will be able to unearth more value for this compound and contribute to the development of the chemical field.
Toxicity Research
The study of physical properties is related to the safety of people. Today there is a compound called Benzene, 1 - Bromo - 4 - Fluoro - 5 - Methyl - 2 - Nitro -, and the study of its toxicity is quite important.
Those who are toxic may hurt the organs or damage the meridians and collaterals, which cannot be ignored. This compound contains bromine, fluorine, nitro and other groups, and its chemical activity is quite high. Bromine and halogens are also easy to react with other substances; nitro has strong oxidizing properties, and both may increase its toxicity. Although fluorine often changes physical properties in organic matter, in this substance, it may also cooperate with other groups to produce toxic effects.
In experimental research, observe its impact on living things. Take mice as a test, and give this substance to observe changes in their behavior and physiology. Or see mice with mental weakness, loss of diet, or signs of pathology in their organs. This shows that the compound is toxic and should be handled with caution to prevent its harm from spreading to the world and endangering sentient beings.
Future Prospects
Looking forward to the future, 1-bromo-4-fluoro-5-methyl-2-nitrobenzene has a remarkable period. Looking at this compound, its structure is unique, containing bromine, fluorine, methyl, and nitro groups, intertwined with each other, and it seems to hold infinite possibilities.
In the process of scientific research, it may be able to use it as a basis to expand the boundaries of organic synthesis. With its characteristics, develop novel reaction paths, create other novel compounds, and add to the treasure house of organic chemistry.
On top of industry, it may become a key intermediate, helping the development of medicine, materials and other industries. In the development of medicine, or it can be ingeniously modified to obtain special drugs to relieve pain; in the field of materials, it can endow materials with unique properties, such as excellent electrical conductivity and optical characteristics, and create a world of new material applications.
Therefore, 1-bromo-4-fluoro-5-methyl-2-nitrobenzene, although it is now in the present, its future prospects are just like the stars are beginning to appear, and the light is waiting to bloom. It will attract scientific research and industry personnel to explore with all their heart, so as to achieve extraordinary success.
Where to Buy Benzene, 1-Bromo-4-Fluoro-5-Methyl-2-Nitro- in China?
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Frequently Asked Questions

As a leading Benzene, 1-Bromo-4-Fluoro-5-Methyl-2-Nitro- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of 1-bromo-4-fluoro-5-methyl-2-nitrobenzene?
1-Hydroxy-4-ene-5-methyl-2-carbonylpyridine, this is an organic compound. Its chemical properties are unique and have the following numbers:
- ** Nucleophilic Substitution Reaction **: The carbonyl group of this compound is a group with strong electronegativity, which causes carbonyl carbons to be positively charged and is prone to attack by nucleophiles, resulting in nucleophilic substitution reactions. In case of alcohol nucleophiles, or ester derivatives; in case of amine nucleophiles, or amide compounds. This reaction is often used in organic synthesis to construct new carbon-heteroatom bonds to prepare diverse functional organic molecules.
- ** Addition reaction **: The carbon-carbon double bond in the molecule can undergo an addition reaction. For example, with the addition of halogen elementals (such as bromine) to form dihalogenated products; with hydrogen halides, following the Markov rule, hydrogen atoms are added to double-bonded carbon atoms with more hydrogen, and halogen atoms are added to double-bonded carbon atoms with less hydrogen. This reaction can introduce halogen atoms into the molecule, increase the reactivity and diversity of the molecule, and lay the foundation for the subsequent synthesis of complex organic compounds.
- ** Redox reaction **: Hydroxyl groups can be oxidized, depending on the oxidation conditions, or oxidized to aldehyde groups and carboxyl groups. If a mild oxidizing agent is used, the hydroxyl group may be oxidized to an aldehyde group; if a strong oxidizing agent is used, it may be further oxidized to a carboxyl group. At the same time, the carbonyl group can also be reduced. For example, reducing agents such as lithium aluminum hydride can reduce the carbonyl group to an alcohol hydroxyl group. Such redox reactions can realize the conversion and modification of functional groups in organic synthesis.
- * Reaction of pyridine rings **: Pyridine rings have certain aromatic properties, but the presence of nitrogen atoms makes the density distribution of cyclic electrons uneven. Pyridine rings can undergo electrophilic substitution reactions, but the reaction activity is lower than that of benzene rings, and more substituents enter the β-position of pyridine rings. In addition, the lone pair electrons of the pyridine ring nitrogen atom can form coordination bonds with metal ions for the preparation of metal complexes, which has potential applications in catalysis, materials science and other fields.
What are the physical properties of 1-bromo-4-fluoro-5-methyl-2-nitrobenzene?
This is an investigation on the physical properties of 1-hydroxy-4-ene-5-methyl-2-furanylnaphthalene. This compound has unique physical properties, is in a crystalline state, is a solid at room temperature, and has a melting point within a certain range. However, the specific value varies depending on the purity and measurement conditions.
In terms of solubility, it shows a certain solubility in organic solvents such as ethanol and acetone. Due to the similar phase dissolution principle, such organic solvents can form an appropriate force between the molecules of the compound to help it disperse and dissolve. However, the solubility in water is very small, because the hydrophobic groups account for a large proportion of the molecular structure, and the force between water molecules is weak.
The compound is volatile to a certain extent, but relatively weak. Its vapor pressure is low at room temperature, causing it to evaporate slowly in the air.
When it comes to density, it is slightly larger than that of common organic solvents. Due to the relatively complex molecular structure, the number and mass of atoms accumulate, resulting in an increase in the mass per unit volume.
In addition, the compound has specific requirements for photothermal stability. Excessive light exposure or high temperature may cause changes in the molecular structure and cause changes in its physical properties. When storing and using, pay attention to the ambient photothermal conditions, and try to store it in a cool and dark place to maintain its physical properties and ensure relevant application effects.
What are the main uses of 1-bromo-4-fluoro-5-methyl-2-nitrobenzene?
1-H-4-H-5-methyl-2-carbonyl indole has important uses in many fields such as medicine and chemical industry.
In the field of medicine, it is a key intermediate in drug synthesis. It is used as the starting material for the preparation of many drugs, and a specific chemical structure is constructed through a series of chemical reactions, thereby endowing the drug with specific pharmacological activity. For example, in the development of anti-tumor drugs, scientists have used their unique chemical structure to modify and develop new drugs that have specific inhibitory effects on tumor cells, or can interfere with the metabolic process of tumor cells, block their growth and proliferation, and provide new avenues for tumor treatment. In terms of neurological drugs, compounds synthesized on this basis may regulate the transmission of neurotransmitters, which has potential value for the treatment of neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease.
In the chemical industry, it is often used to synthesize functional materials. For example, in the preparation of organic photoelectric materials, it can be introduced into the material structure to improve the photoelectric properties of the material, such as improving the fluorescence efficiency and charge transport ability of the material, etc., for the manufacture of better photoelectric devices such as Light Emitting Diode and solar cells; in the coating industry, compounds containing such structures can be used as additives to improve the adhesion, corrosion resistance and other properties of the coating, and prolong the service life of the coated object.
It can be seen that 1-4-Jiang-5-methyl-2-carbonyl indole plays a key role in the pharmaceutical and chemical industries, and is of great significance to promoting the development of related fields.
What are the synthesis methods of 1-bromo-4-fluoro-5-methyl-2-nitrobenzene?
To prepare 1-bromo-4-pentene-5-methyl-2-hydroxybenzene, the following ancient method can be used.
First, use 4-pentene-5-methyl-2-hydroxybenzene as the starting material. First, the raw material is reacted with an appropriate amount of brominating agent in a suitable solvent. If liquid bromine is used as the brominating agent, in an inert solvent such as carbon tetrachloride, under low temperature and dark conditions, slowly add liquid bromine dropwise and stir at the same time. Because the hydroxyl group and the methyl group are ortho-para-sites, the bromine atom will mainly replace the hydroxyl group to form the target product 1-bromo-4-pentene-5-methyl-2-hydroxybenzene. However, this process needs to pay attention to the amount of bromine, and excessive bromide is easy to cause the formation of polybrominated by-products.
Second, 4-pentene-5-methyl-2-hydroxybenzene can also be used to protect the hydroxyl group. Appropriate protective groups can be selected, such as treating the raw material with acetyl chloride and pyridine, so that the hydroxyl group is converted into acetoxy group to obtain the protected product. Subsequently, N-bromosuccinimide (NBS) is used as a brominating agent, and the reflux reaction is heated in a carbon tetrachloride solvent in the presence of an initiator such as benzoyl peroxide. NBS can selectively bromine the allyl position to form allyl bromide. After the bromination reaction is completed, it is treated with a basic reagent such as sodium hydroxide aqueous solution to remove the acetyl protection and regenerate the hydroxyl group to obtain 1-bromo-4-pentene-5-methyl-2-hydroxybenzene. Although this approach is slightly complicated, it can effectively avoid the interference of hydroxyl groups on the bromination reaction and improve the purity and yield of the product.
Third, the Grignard reagent method can also be used. First, the corresponding Grignard reagent is prepared by reacting 4-pentene-5-methyl-2-iodobenzene with magnesium chips in anhydrous ether. After that, the Grignard reagent is slowly added dropwise to the system containing brominated reagents. If reacted with copper bromide, after a series of conversions, 1-bromo-4-pentene-5-methyl-2-hydroxybenzene can also be obtained. This method requires strict anhydrous and anaerobic operation to ensure the activity and stability of the Grignard reagent.
What are the environmental effects of 1-bromo-4-fluoro-5-methyl-2-nitrobenzene?
The environmental impact of 1 + -mercury-4 + -river-5 + -methyl-2 + -hydroxybenzoic acid needs to be carefully reviewed. Mercury, a highly toxic metal, can undergo multiple transformations in the natural environment. In water bodies, mercury is easily enriched in aquatic organisms, progressing through the food chain layer by layer, eventually causing high-level organisms and even humans to suffer from it, damaging the nervous and immune systems.
Rivers are important to natural water systems. If they are attacked by pollutants such as mercury and methyl, the water quality will deteriorate, and the aquatic ecological balance will be greatly disrupted. The reproduction and survival of aquatic organisms are facing crisis, and biodiversity will decrease sharply. The addition of
methyl group may exacerbate the chemical activity and toxicity of mercury, and change the characteristics of migration and transformation in the environment. It is more likely to penetrate into soil and sediments, and will remain for a long time, causing far-reaching harm.
Although 2-hydroxybenzoic acid has different properties from mercury and methyl group, it cannot be ignored in the environment. It may participate in the chemical processes of water bodies and soils, interfering with the normal metabolism of ecosystems. In soil, it may affect the structure and function of soil microbial communities, causing changes in soil fertility and self-purification capacity. In water bodies, or change the chemical composition of water bodies, affecting the growth of aquatic plants such as algae, and then affecting the entire aquatic food chain.
Mercury, river, methyl and 2-hydroxybenzoic acid interact with the environment, and their effects are complex. Either synergistically exacerbate pollution hazards, or interfere with each other's transformation process, making it increasingly difficult to analyze and deal with environmental problems. Only by understanding its mechanism can we implement precise measures to protect the environment and ecology.